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The map label for this gene is deoC

Identifier: 28377388

GI number: 28377388

Start: 444089

End: 444736

Strand: Direct

Name: deoC

Synonym: lp_0497

Alternate gene names: 28377388

Gene position: 444089-444736 (Clockwise)

Preceding gene: 28377387

Following gene: 28377389

Centisome position: 13.42

GC content: 46.14

Gene sequence:

>648_bases
ATGAAATTGAATCGTTATTTAGATCACACGTTATTAAAACCGGAAGCGACTGAGCAACAAATTGATCAGGTAGTACGGGA
GGCACTCGAAAATCACTTTTATTCAGTTATGGTCAATCCATACTGGGTCAAGCACGTCCATGCGCAACTTGCTGGTTCGG
ATGTTGCGACTGCATGCGTGATTGGTTTCCCTCTGGGCGCGAATACAACCGCCATTAAAGTTGCGGAAGCCAAACAGGCA
ATTGCTGACGGTGTGGATGAGCTGGATATGGTCATTAATATCGGCGAATTGAAAGGCGACCACTATGATGCAGTTCAACA
AGACATTGAAAGTGTGGTAACAGTTGGACATACGGCTGATAAGGTCGTCAAAGTGATTATTGAAACGGCGCTGTTGACGG
ATGGGGAAATCGTTAAGGCTAGTGAAATTGTTGCCGATGCACACGCTGATTTTGTGAAGACATCGACTGGATTTTCAACC
CGTGGTGCTTCGGTTCATGATATTAGTTTGATGAAGGGTGCCGTTCAGGATCGAATCGGGGTCAAAGCATCTGGGGGAAT
CCATACACGCGATGAAGCATTAGCGATGATTGATGCTGGAGCAACGCGCCTCGGTGTATCAGCAAGTATGGCAATTATTG
GTAAGTAG

Upstream 100 bases:

>100_bases
AGCATAAACGCCGAAATGAACAAAATTTCAAATGTAGTATTTACAAATGTTCAGTTCGTGATATACTGAAGTTGTTAAAA
AGAAAGGGGTTTCATTAATC

Downstream 100 bases:

>100_bases
TGATGGCTGAATGATTGCGCACCATTCCAGTTTAAAAAAAGAAAGCGCTAACATCAAGGAGGGGAACCATGCAAAAGTTA
TTTCGGGGTGTGATTAAGCT

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKLNRYLDHTLLKPEATEQQIDQVVREALENHFYSVMVNPYWVKHVHAQLAGSDVATACVIGFPLGANTTAIKVAEAKQA
IADGVDELDMVINIGELKGDHYDAVQQDIESVVTVGHTADKVVKVIIETALLTDGEIVKASEIVADAHADFVKTSTGFST
RGASVHDISLMKGAVQDRIGVKASGGIHTRDEALAMIDAGATRLGVSASMAIIGK

Sequences:

>Translated_215_residues
MKLNRYLDHTLLKPEATEQQIDQVVREALENHFYSVMVNPYWVKHVHAQLAGSDVATACVIGFPLGANTTAIKVAEAKQA
IADGVDELDMVINIGELKGDHYDAVQQDIESVVTVGHTADKVVKVIIETALLTDGEIVKASEIVADAHADFVKTSTGFST
RGASVHDISLMKGAVQDRIGVKASGGIHTRDEALAMIDAGATRLGVSASMAIIGK
>Mature_215_residues
MKLNRYLDHTLLKPEATEQQIDQVVREALENHFYSVMVNPYWVKHVHAQLAGSDVATACVIGFPLGANTTAIKVAEAKQA
IADGVDELDMVINIGELKGDHYDAVQQDIESVVTVGHTADKVVKVIIETALLTDGEIVKASEIVADAHADFVKTSTGFST
RGASVHDISLMKGAVQDRIGVKASGGIHTRDEALAMIDAGATRLGVSASMAIIGK

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=164, Percent_Identity=31.7073170731707, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1790841, Length=200, Percent_Identity=28, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17533015, Length=214, Percent_Identity=28.5046728971963, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_LACPL (Q88Z64)

Other databases:

- EMBL:   AL935253
- RefSeq:   NP_784280.1
- ProteinModelPortal:   Q88Z64
- SMR:   Q88Z64
- GeneID:   1061480
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_0497
- NMPDR:   fig|220668.1.peg.414
- HOGENOM:   HBG636421
- OMA:   GANTPEV
- ProtClustDB:   PRK00507
- BioCyc:   LPLA220668:LP_0497-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 22886; Mature: 22886

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: ACT_SITE 153-153 ACT_SITE 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNRYLDHTLLKPEATEQQIDQVVREALENHFYSVMVNPYWVKHVHAQLAGSDVATACV
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCHHHHHHH
IGFPLGANTTAIKVAEAKQAIADGVDELDMVINIGELKGDHYDAVQQDIESVVTVGHTAD
EECCCCCCCEEEEHHHHHHHHHCCHHHHHHEEEHHHHCCCHHHHHHHHHHHHHHCCCCHH
KVVKVIIETALLTDGEIVKASEIVADAHADFVKTSTGFSTRGASVHDISLMKGAVQDRIG
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
VKASGGIHTRDEALAMIDAGATRLGVSASMAIIGK
CCCCCCCCCHHHHHEEECCCCHHHCCCCCEEEECC
>Mature Secondary Structure
MKLNRYLDHTLLKPEATEQQIDQVVREALENHFYSVMVNPYWVKHVHAQLAGSDVATACV
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCHHHHHHH
IGFPLGANTTAIKVAEAKQAIADGVDELDMVINIGELKGDHYDAVQQDIESVVTVGHTAD
EECCCCCCCEEEEHHHHHHHHHCCHHHHHHEEEHHHHCCCHHHHHHHHHHHHHHCCCCHH
KVVKVIIETALLTDGEIVKASEIVADAHADFVKTSTGFSTRGASVHDISLMKGAVQDRIG
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
VKASGGIHTRDEALAMIDAGATRLGVSASMAIIGK
CCCCCCCCCHHHHHEEECCCCHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566