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The map label for this gene is yydK [H]

Identifier: 28377338

GI number: 28377338

Start: 389246

End: 389956

Strand: Direct

Name: yydK [H]

Synonym: lp_0435

Alternate gene names: 28377338

Gene position: 389246-389956 (Clockwise)

Preceding gene: 28377337

Following gene: 28377339

Centisome position: 11.77

GC content: 46.41

Gene sequence:

>711_bases
ATGTATCAGGCAATTGCGCAGGCAATCATTAAATCGATAATGGCGGATGAATATCCGACTAAGTTACCAACCGAAAAAGT
GTTAATGGCGCAGTACAACGCCAGTCGCAATACGATTCGTAAAGCGATTGATGTGGTCTTCCGGCATGGGTTGTTACGTC
GCGTGCAGGGGAGCGGCAATTTTATTATCAAACAACCGCAGAACACGAAGAAAGTGCTCAACTTATCGATTGGATTTGAC
CAGTCCGCCATGGTTGACGGTGGACCATTAGTATCAAAAGTTGTCACGTTTGATAAAGTGACAGCGGATGAAACTTTAGC
ACAACAGGGGAACATTGCGCTTGGTGACGAGGTTTATCGGGTGGTGCGATTACGTTATTTGAATGACATCTTGTATGACC
TGGAAGAGTCTTATTTTCCGCGAACGGTCGTCCCGTTCTTATCGAGTGAGAGCGTGCAGCATTCAATCTTCGCCTTCTTG
CGAGAGGCATATGGTATTACGGGGAGCACCACGGAAAACTACGTCCATCAAGTGCGGGTGGACGCGCAACGGGCGGAGTT
GATCGGTTGCCCAGATGGTGACAAAACGTTGTGCTTGGAAGCAATCAATTACTTGGCTAATGGGACGGTCTTTAACTTCT
CCAGGACGTTCTTCGTCTATCCAGATTTGGAACTCTATTACCATACCGAAAATATTGATTTACAAAACTAG

Upstream 100 bases:

>100_bases
AATTACGAAAAATAAAGCGTTTTCATATATTCTGTGATAATATAATTTGTGGGCACAAGTTTTACAAGCACCTACTAATT
TATCGAAAGGAGGTTTAGTC

Downstream 100 bases:

>100_bases
TACGGGGGTGACGCAACAGTTGTGTTGGGTCACTAACTAGCGAAAACCTACATTAGGAGTGAGGGGTATATTATGAATTC
ATTTATCGAATGGCTTAACA

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MYQAIAQAIIKSIMADEYPTKLPTEKVLMAQYNASRNTIRKAIDVVFRHGLLRRVQGSGNFIIKQPQNTKKVLNLSIGFD
QSAMVDGGPLVSKVVTFDKVTADETLAQQGNIALGDEVYRVVRLRYLNDILYDLEESYFPRTVVPFLSSESVQHSIFAFL
REAYGITGSTTENYVHQVRVDAQRAELIGCPDGDKTLCLEAINYLANGTVFNFSRTFFVYPDLELYYHTENIDLQN

Sequences:

>Translated_236_residues
MYQAIAQAIIKSIMADEYPTKLPTEKVLMAQYNASRNTIRKAIDVVFRHGLLRRVQGSGNFIIKQPQNTKKVLNLSIGFD
QSAMVDGGPLVSKVVTFDKVTADETLAQQGNIALGDEVYRVVRLRYLNDILYDLEESYFPRTVVPFLSSESVQHSIFAFL
REAYGITGSTTENYVHQVRVDAQRAELIGCPDGDKTLCLEAINYLANGTVFNFSRTFFVYPDLELYYHTENIDLQN
>Mature_236_residues
MYQAIAQAIIKSIMADEYPTKLPTEKVLMAQYNASRNTIRKAIDVVFRHGLLRRVQGSGNFIIKQPQNTKKVLNLSIGFD
QSAMVDGGPLVSKVVTFDKVTADETLAQQGNIALGDEVYRVVRLRYLNDILYDLEESYFPRTVVPFLSSESVQHSIFAFL
REAYGITGSTTENYVHQVRVDAQRAELIGCPDGDKTLCLEAINYLANGTVFNFSRTFFVYPDLELYYHTENIDLQN

Specific function: Possible Transcriptional Regulator Of The Succinyl-CoA- Synthetase Operon. Binds Specifically To The Farr Promoter And Exhibits Weak Binding To The Citrate Synthase And Lipoamide Dehydrogenase Promoters. Binding At The Farr Promoter Is Abolished By Long-

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=220, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790118, Length=237, Percent_Identity=25.3164556962025, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI87082252, Length=220, Percent_Identity=25.4545454545455, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1790540, Length=185, Percent_Identity=27.5675675675676, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26694; Mature: 26694

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQAIAQAIIKSIMADEYPTKLPTEKVLMAQYNASRNTIRKAIDVVFRHGLLRRVQGSGN
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
FIIKQPQNTKKVLNLSIGFDQSAMVDGGPLVSKVVTFDKVTADETLAQQGNIALGDEVYR
EEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHH
VVRLRYLNDILYDLEESYFPRTVVPFLSSESVQHSIFAFLREAYGITGSTTENYVHQVRV
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
DAQRAELIGCPDGDKTLCLEAINYLANGTVFNFSRTFFVYPDLELYYHTENIDLQN
CHHHHHEEECCCCCHHHHHHHHHHHHCCCEEEECEEEEEECCEEEEEEECCCCCCC
>Mature Secondary Structure
MYQAIAQAIIKSIMADEYPTKLPTEKVLMAQYNASRNTIRKAIDVVFRHGLLRRVQGSGN
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
FIIKQPQNTKKVLNLSIGFDQSAMVDGGPLVSKVVTFDKVTADETLAQQGNIALGDEVYR
EEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHH
VVRLRYLNDILYDLEESYFPRTVVPFLSSESVQHSIFAFLREAYGITGSTTENYVHQVRV
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
DAQRAELIGCPDGDKTLCLEAINYLANGTVFNFSRTFFVYPDLELYYHTENIDLQN
CHHHHHEEECCCCCHHHHHHHHHHHHCCCEEEECEEEEEECCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]