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The map label for this gene is pts7C [H]

Identifier: 28377339

GI number: 28377339

Start: 390029

End: 391390

Strand: Direct

Name: pts7C [H]

Synonym: lp_0436

Alternate gene names: 28377339

Gene position: 390029-391390 (Clockwise)

Preceding gene: 28377338

Following gene: 28377340

Centisome position: 11.79

GC content: 46.11

Gene sequence:

>1362_bases
ATGAATTCATTTATCGAATGGCTTAACAAACACTTAGTGCCAGTTGCGGCCAAGATTGGTGCAGTTCGGTGGTTGATCGC
ATTACGTGACGCGTTTATAGCAATTATGCCGGCAATGATGGCCGGGTCGATCGCCACGGTTCTGAACGCTTTAGTTCGAG
ATATTCCAACGAAGTTCGGTTGGATGGGCATTGTTAATTCGATGCAGTGGTTGATTGGAATTAATGCGATGGTTTGGACG
GGGACGTTAGCCATCTTAGGTCTGATTTTCTCATTTACATTCGGGTATCAATTGGCAATCCAGTACAAAGTTGAACCAGT
TACTGGTGGGATCGTGACACTTGGAACTTTCATCATGAGTTTGCCACAAAACTTTACCGGCACGTTGACGAGTACGTTGA
GCAAGGGCGCTACTAAGATTTTGACGGACTCTGGCATGGCGGTTGCTGGCAAAAAAGTGACGGCTTGGGGTTACTTCAAC
TTCAACACGTACTTTGGTTCGTATGGTTTCTTTACGGTCATGATTTTAGGGGCCATTGCGAGTGCCGTTTACATTGCTTT
GATGAAGAAACACATTACAATCAAGATGCCAGATTCTGTGCCACCGGCAGTTGCAAACGCCTTCACTGGGGTTATCCCAG
CCGCCGCTGCATTTTATGTCGTTGGGATTATTAACTGGATCTTCAGTAAATTCAACACCACGGTGATTGAATGGATCGCG
AAGATTATTCAAGAACCACTATTGAATATGAGTCAAGGGTACGGCGCCGTCCTCTTAATGACGCTGTTAGTTCAAGTTTT
CTGGTTCTTCGGGATTCATGGTTCCAATGTCCTGGCACCAATCTTGGACGGAATCTGGTTGACGGCTCAGCTTGCTAATG
TTAACGCTTACCAAGCTGGCAAAGCCTTGCCATACGTTTGGACGCGGAACTGTTTTGACTTATATGCATGGATTGGTGGG
GCCGGCTCGACCTTACTATTATTAGTAGCGATTTTAGTATTTAGTAAACGAGACGACCAACGTTCAGTGGCTAAGTTGGC
GATTGGCCCCGGATTCTTTAATATTAACGAACCCGTGATGTTCGGGATGCCAATTGTACTTGACCCAATCTACTTTATTC
CGTTCGTTTTAGCACCAGTTGTGACTGTTTCGATCGCCTACGCTGCTTTATCAGCTGGGTGGGTCGCACCGATTACGAAC
AATATCGTTTGGTCAATGCCACCGATTATGAACGCCTTAGTTGCCACAATGGACTGGCGGTCAGTGGTCTTACAATTATT
TAATGCCGCCGTTGCCTTTGCGATTTACGTGCCATTCGTTAAGGCTGCCAACAAGATTAAACCAGCAGCGATTGGAGAAT
AG

Upstream 100 bases:

>100_bases
TACCGAAAATATTGATTTACAAAACTAGTACGGGGGTGACGCAACAGTTGTGTTGGGTCACTAACTAGCGAAAACCTACA
TTAGGAGTGAGGGGTATATT

Downstream 100 bases:

>100_bases
ATTGTCATGAAAAGCTTAAAGCAGTGTTTACTCATCGGGATGAACCTTGGATTATTAGCCGTTATCTTAAGTCCCCTGGC
CGGAACGACCGGTCAATGGG

Product: cellobiose PTS, EIIC

Products: protein histidine; sugar phosphate

Alternate protein names: Glucomannan utilization protein C; PTS system oligo-beta-mannoside-specific EIIC component [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MNSFIEWLNKHLVPVAAKIGAVRWLIALRDAFIAIMPAMMAGSIATVLNALVRDIPTKFGWMGIVNSMQWLIGINAMVWT
GTLAILGLIFSFTFGYQLAIQYKVEPVTGGIVTLGTFIMSLPQNFTGTLTSTLSKGATKILTDSGMAVAGKKVTAWGYFN
FNTYFGSYGFFTVMILGAIASAVYIALMKKHITIKMPDSVPPAVANAFTGVIPAAAAFYVVGIINWIFSKFNTTVIEWIA
KIIQEPLLNMSQGYGAVLLMTLLVQVFWFFGIHGSNVLAPILDGIWLTAQLANVNAYQAGKALPYVWTRNCFDLYAWIGG
AGSTLLLLVAILVFSKRDDQRSVAKLAIGPGFFNINEPVMFGMPIVLDPIYFIPFVLAPVVTVSIAYAALSAGWVAPITN
NIVWSMPPIMNALVATMDWRSVVLQLFNAAVAFAIYVPFVKAANKIKPAAIGE

Sequences:

>Translated_453_residues
MNSFIEWLNKHLVPVAAKIGAVRWLIALRDAFIAIMPAMMAGSIATVLNALVRDIPTKFGWMGIVNSMQWLIGINAMVWT
GTLAILGLIFSFTFGYQLAIQYKVEPVTGGIVTLGTFIMSLPQNFTGTLTSTLSKGATKILTDSGMAVAGKKVTAWGYFN
FNTYFGSYGFFTVMILGAIASAVYIALMKKHITIKMPDSVPPAVANAFTGVIPAAAAFYVVGIINWIFSKFNTTVIEWIA
KIIQEPLLNMSQGYGAVLLMTLLVQVFWFFGIHGSNVLAPILDGIWLTAQLANVNAYQAGKALPYVWTRNCFDLYAWIGG
AGSTLLLLVAILVFSKRDDQRSVAKLAIGPGFFNINEPVMFGMPIVLDPIYFIPFVLAPVVTVSIAYAALSAGWVAPITN
NIVWSMPPIMNALVATMDWRSVVLQLFNAAVAFAIYVPFVKAANKIKPAAIGE
>Mature_453_residues
MNSFIEWLNKHLVPVAAKIGAVRWLIALRDAFIAIMPAMMAGSIATVLNALVRDIPTKFGWMGIVNSMQWLIGINAMVWT
GTLAILGLIFSFTFGYQLAIQYKVEPVTGGIVTLGTFIMSLPQNFTGTLTSTLSKGATKILTDSGMAVAGKKVTAWGYFN
FNTYFGSYGFFTVMILGAIASAVYIALMKKHITIKMPDSVPPAVANAFTGVIPAAAAFYVVGIINWIFSKFNTTVIEWIA
KIIQEPLLNMSQGYGAVLLMTLLVQVFWFFGIHGSNVLAPILDGIWLTAQLANVNAYQAGKALPYVWTRNCFDLYAWIGG
AGSTLLLLVAILVFSKRDDQRSVAKLAIGPGFFNINEPVMFGMPIVLDPIYFIPFVLAPVVTVSIAYAALSAGWVAPITN
NIVWSMPPIMNALVATMDWRSVVLQLFNAAVAFAIYVPFVKAANKIKPAAIGE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=474, Percent_Identity=31.4345991561181, Blast_Score=210, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 49169; Mature: 49169

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS51105 PTS_EIIC_TYPE_3 ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFIEWLNKHLVPVAAKIGAVRWLIALRDAFIAIMPAMMAGSIATVLNALVRDIPTKFG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
WMGIVNSMQWLIGINAMVWTGTLAILGLIFSFTFGYQLAIQYKVEPVTGGIVTLGTFIMS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCHHHHHHHHHHH
LPQNFTGTLTSTLSKGATKILTDSGMAVAGKKVTAWGYFNFNTYFGSYGFFTVMILGAIA
CCCCCCHHHHHHHHCCCHHHEECCCCEEECCEEEEEEEEECHHHHCCHHHHHHHHHHHHH
SAVYIALMKKHITIKMPDSVPPAVANAFTGVIPAAAAFYVVGIINWIFSKFNTTVIEWIA
HHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIIQEPLLNMSQGYGAVLLMTLLVQVFWFFGIHGSNVLAPILDGIWLTAQLANVNAYQAG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHEECCCCHHHCC
KALPYVWTRNCFDLYAWIGGAGSTLLLLVAILVFSKRDDQRSVAKLAIGPGFFNINEPVM
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHEECCCCCCCCCCHH
FGMPIVLDPIYFIPFVLAPVVTVSIAYAALSAGWVAPITNNIVWSMPPIMNALVATMDWR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHH
SVVLQLFNAAVAFAIYVPFVKAANKIKPAAIGE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNSFIEWLNKHLVPVAAKIGAVRWLIALRDAFIAIMPAMMAGSIATVLNALVRDIPTKFG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
WMGIVNSMQWLIGINAMVWTGTLAILGLIFSFTFGYQLAIQYKVEPVTGGIVTLGTFIMS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCHHHHHHHHHHH
LPQNFTGTLTSTLSKGATKILTDSGMAVAGKKVTAWGYFNFNTYFGSYGFFTVMILGAIA
CCCCCCHHHHHHHHCCCHHHEECCCCEEECCEEEEEEEEECHHHHCCHHHHHHHHHHHHH
SAVYIALMKKHITIKMPDSVPPAVANAFTGVIPAAAAFYVVGIINWIFSKFNTTVIEWIA
HHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIIQEPLLNMSQGYGAVLLMTLLVQVFWFFGIHGSNVLAPILDGIWLTAQLANVNAYQAG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHEECCCCHHHCC
KALPYVWTRNCFDLYAWIGGAGSTLLLLVAILVFSKRDDQRSVAKLAIGPGFFNINEPVM
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHEECCCCCCCCCCHH
FGMPIVLDPIYFIPFVLAPVVTVSIAYAALSAGWVAPITNNIVWSMPPIMNALVATMDWR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHH
SVVLQLFNAAVAFAIYVPFVKAANKIKPAAIGE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]