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The map label for this gene is pts6C [H]

Identifier: 28377210

GI number: 28377210

Start: 259439

End: 260764

Strand: Direct

Name: pts6C [H]

Synonym: lp_0286

Alternate gene names: 28377210

Gene position: 259439-260764 (Clockwise)

Preceding gene: 28377209

Following gene: 28377212

Centisome position: 7.84

GC content: 45.02

Gene sequence:

>1326_bases
ATGAGCGAAAACAATAACAAGTCGAGCTTTGTTAATGACCGACTTGTCCCTTTCTTTGGCAAGATTGCTGGTTCTCGTCA
CTTAATTGCCTTACGTGATGGGATGACATTGGCAGTGCCAATGATTATTATCGGGTCGGTCTTCATGATCATTGCGCAAT
TCCCTATCAAGGGTTATCAGACCTTTATGGCCAATACCTTTGGTTCGAATTGGTCAACGATCGTCCAATATCCAACTAAC
GCCTCGTTCCATATCATGGGCTTGATTGCGGTTATTGGGATTTCTTATAACTTGGCAAAGAGTTATAAAGTCGATCCAAT
CTCTGCCTCAATTGTTTCGTTAGGCGCTTGGTTCTTAACGATTCCATTAAACACCGATAAGGCAGGAGCACTGTGGGTAC
CATTAACCCAACTTGATTCGGCGGGGTTATTCACGGCGCTACTGATTGGGTTGTTTATTACTGATTTTTACGTTTTCATG
GTGCATCGCAATTGGACGATTAAGATGCCTGATAGCGTGCCACCGGCAGTTAGCAACTCGTTTGCAGCCTTAGTACCCGG
TTTCGTCATCTTATTCTTGATGTGGTTACTGCGGTTGGCTGTTGAAGCATCACCAATGCAGAGTATTCCTAACGTGATTT
CATTCGTCTTAGCTAAACCATTAGGCTTGTTGAGTAACACGTTACCAGGGGCCTTGGTTGCTGAATTCGTTGTATGTATT
CTTTGGATTTTCGGGATTCACGGTGCCAACGTGGTTTCTGGGGTCATGCAACCAATCTGGTTAGCTGCGATGTCTCAAAA
CGCGGAAGCGCTTAAGGCTGGTAAGGCTTTACCAAACGTTGTGACACAACAATTCTTCGACAACTTTGTCCACATGGGTG
GTTCCGGTGCGACCTTGGGATTAGCTTTCATGATTGCCTTTGTTGCCAAGAGTGCCGAATTCAAGACATTAGGTAAGCTG
GTTATCGGACCCGCACTGTTCAATATCAATGAACCGATTGTCTTCGGGTTGCCAATCGTTATGAACTATCGGATTGCCGT
TCCGTTTATCTTGGCACCGTTAGTTAATGTTACGACGACTTACATTGCAATGTCGACGGGCTTAGTTGCAAAGACGGTTG
GGGTCATGGTTCCTTGGACGACGCCGCCAATTATCTCTGGTTACTTAGCAACGATGCACATCTCAGGTGCGGTATTACAA
ATTGTTAATATTGTGCTTGATGGTGCCATCTACTACTTCTTCTTCAAGGCCTTAGATCGTGATAAGGTTAAGGAAGAAAA
GACCTTTGCTGCTAAAGAAGCTGCTGGCGAAACGGTCGAAGCTTAA

Upstream 100 bases:

>100_bases
TTAACTATTGATTGACCGTTAGCTTACTTAAATTATTCTGATTGTTTGAGAATGTTCGTTAAATGAATATGCACAACAAA
TTATTTTAGGGGGTCACGAC

Downstream 100 bases:

>100_bases
GTTAAATCATTAATGTAGTAATCGTATAAATACCACCATTAGCGACTTGCTGAAAGTCTGTTGATGGTGGTATTTTAATA
TCGATTTTTGAGAAGCGCGT

Product: cellobiose PTS, EIIC

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSENNNKSSFVNDRLVPFFGKIAGSRHLIALRDGMTLAVPMIIIGSVFMIIAQFPIKGYQTFMANTFGSNWSTIVQYPTN
ASFHIMGLIAVIGISYNLAKSYKVDPISASIVSLGAWFLTIPLNTDKAGALWVPLTQLDSAGLFTALLIGLFITDFYVFM
VHRNWTIKMPDSVPPAVSNSFAALVPGFVILFLMWLLRLAVEASPMQSIPNVISFVLAKPLGLLSNTLPGALVAEFVVCI
LWIFGIHGANVVSGVMQPIWLAAMSQNAEALKAGKALPNVVTQQFFDNFVHMGGSGATLGLAFMIAFVAKSAEFKTLGKL
VIGPALFNINEPIVFGLPIVMNYRIAVPFILAPLVNVTTTYIAMSTGLVAKTVGVMVPWTTPPIISGYLATMHISGAVLQ
IVNIVLDGAIYYFFFKALDRDKVKEEKTFAAKEAAGETVEA

Sequences:

>Translated_441_residues
MSENNNKSSFVNDRLVPFFGKIAGSRHLIALRDGMTLAVPMIIIGSVFMIIAQFPIKGYQTFMANTFGSNWSTIVQYPTN
ASFHIMGLIAVIGISYNLAKSYKVDPISASIVSLGAWFLTIPLNTDKAGALWVPLTQLDSAGLFTALLIGLFITDFYVFM
VHRNWTIKMPDSVPPAVSNSFAALVPGFVILFLMWLLRLAVEASPMQSIPNVISFVLAKPLGLLSNTLPGALVAEFVVCI
LWIFGIHGANVVSGVMQPIWLAAMSQNAEALKAGKALPNVVTQQFFDNFVHMGGSGATLGLAFMIAFVAKSAEFKTLGKL
VIGPALFNINEPIVFGLPIVMNYRIAVPFILAPLVNVTTTYIAMSTGLVAKTVGVMVPWTTPPIISGYLATMHISGAVLQ
IVNIVLDGAIYYFFFKALDRDKVKEEKTFAAKEAAGETVEA
>Mature_440_residues
SENNNKSSFVNDRLVPFFGKIAGSRHLIALRDGMTLAVPMIIIGSVFMIIAQFPIKGYQTFMANTFGSNWSTIVQYPTNA
SFHIMGLIAVIGISYNLAKSYKVDPISASIVSLGAWFLTIPLNTDKAGALWVPLTQLDSAGLFTALLIGLFITDFYVFMV
HRNWTIKMPDSVPPAVSNSFAALVPGFVILFLMWLLRLAVEASPMQSIPNVISFVLAKPLGLLSNTLPGALVAEFVVCIL
WIFGIHGANVVSGVMQPIWLAAMSQNAEALKAGKALPNVVTQQFFDNFVHMGGSGATLGLAFMIAFVAKSAEFKTLGKLV
IGPALFNINEPIVFGLPIVMNYRIAVPFILAPLVNVTTTYIAMSTGLVAKTVGVMVPWTTPPIISGYLATMHISGAVLQI
VNIVLDGAIYYFFFKALDRDKVKEEKTFAAKEAAGETVEA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=454, Percent_Identity=30.3964757709251, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 47656; Mature: 47525

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENNNKSSFVNDRLVPFFGKIAGSRHLIALRDGMTLAVPMIIIGSVFMIIAQFPIKGYQ
CCCCCCCCHHHCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHH
TFMANTFGSNWSTIVQYPTNASFHIMGLIAVIGISYNLAKSYKVDPISASIVSLGAWFLT
HHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHCEEEEE
IPLNTDKAGALWVPLTQLDSAGLFTALLIGLFITDFYVFMVHRNWTIKMPDSVPPAVSNS
EECCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHEECCEEEECCCCCCCHHCCC
FAALVPGFVILFLMWLLRLAVEASPMQSIPNVISFVLAKPLGLLSNTLPGALVAEFVVCI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LWIFGIHGANVVSGVMQPIWLAAMSQNAEALKAGKALPNVVTQQFFDNFVHMGGSGATLG
HHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHH
LAFMIAFVAKSAEFKTLGKLVIGPALFNINEPIVFGLPIVMNYRIAVPFILAPLVNVTTT
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
YIAMSTGLVAKTVGVMVPWTTPPIISGYLATMHISGAVLQIVNIVLDGAIYYFFFKALDR
HHHHHCCHHHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKVKEEKTFAAKEAAGETVEA
HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SENNNKSSFVNDRLVPFFGKIAGSRHLIALRDGMTLAVPMIIIGSVFMIIAQFPIKGYQ
CCCCCCCHHHCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHH
TFMANTFGSNWSTIVQYPTNASFHIMGLIAVIGISYNLAKSYKVDPISASIVSLGAWFLT
HHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHCEEEEE
IPLNTDKAGALWVPLTQLDSAGLFTALLIGLFITDFYVFMVHRNWTIKMPDSVPPAVSNS
EECCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHEECCEEEECCCCCCCHHCCC
FAALVPGFVILFLMWLLRLAVEASPMQSIPNVISFVLAKPLGLLSNTLPGALVAEFVVCI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LWIFGIHGANVVSGVMQPIWLAAMSQNAEALKAGKALPNVVTQQFFDNFVHMGGSGATLG
HHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHH
LAFMIAFVAKSAEFKTLGKLVIGPALFNINEPIVFGLPIVMNYRIAVPFILAPLVNVTTT
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
YIAMSTGLVAKTVGVMVPWTTPPIISGYLATMHISGAVLQIVNIVLDGAIYYFFFKALDR
HHHHHCCHHHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKVKEEKTFAAKEAAGETVEA
HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]