| Definition | Lactobacillus plantarum WCFS1, complete genome. |
|---|---|
| Accession | NC_004567 |
| Length | 3,308,274 |
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The map label for this gene is mtlR [H]
Identifier: 28377161
GI number: 28377161
Start: 210788
End: 212863
Strand: Direct
Name: mtlR [H]
Synonym: lp_0231
Alternate gene names: 28377161
Gene position: 210788-212863 (Clockwise)
Preceding gene: 28377160
Following gene: 28377162
Centisome position: 6.37
GC content: 45.47
Gene sequence:
>2076_bases ATGGTTAAGTTTACACAACGTCAAGATGAGTTGCTACAGCTGCTACTAGCGAATCCCGCCGGCCTTTCAATGAGTCAGAT TGAAACCGGTCTCAATAGTAGTCGCCGAACAATTTATCGCGAGTTCAGTAATTTGGAATTGGTATTAGCCAATGCTGATT TGAAAATTGTTAATGAGAAGCATCACTTTCAACTAAGTGGATCGCAGACGGCCCTGGCCAAGTTTCAAAGCCAATTGACA GCAGAGCGGAAGATTGCACCGGCGTTTGACTCACAAACGCGGCAAAACGCCCTAGCTTGTCGGTTACTGATGACGGGCCA TTCCGTAAAATTAAAAGAACTTGCGCTTGACTTTGATGTGAGCGTTGCAACGATTTCAAACGATTTAACGGCATTAGCAA CGCCATTCGCCGACTACGACTTATCGATTGAACGGTTGAAGTCCCGGGGGATTCAGGTGGCGGGGACTGAGGGTAGTATT CGCAATCTGTTTGCCACCATTTTGAATAATGAAATCAACGACTACGAGTTTTTTAAAACAATCGGGAAGTTGAACCAAGG CTTAGCAATATCAGCAAGTGATGAGCAATCGTATTTTTTGAACTTACTGGACGCCCAAACGTTGATTATCTGTTATCAAG CAGTGCGAAGTTTAAAGAAAAAGTACTTTTCTTCGGTGCCGGATGGTCAGCTACAACAGTTGATCATCACGTTGACGACG GGAGTAATGCGGTTACAGCATGAGCGTCGGGTCACGTATTTGCGCGGGATCAATCGGGATGATTTCTTGAAATATCAACG GATTGCTCTGGCAATTATGACCCAACTACCCGCTGAGATTAAGACGGTGGTGACGGGAGCTGAAATTGATTTTCTCGCCC AGCAAATTAAGGGCTTGACGTTTCGAATCGATCAAGACGCGTCGCTATCGAATTATGATTTGCAACTAACGTATCGGGTC AAAAAGTTTATTGACGCGGTTGCGACTAACTTTAACTGGTCGTTTGGGACGGATGACCGCTTGTTGAATAACTTGACGGC ACATATGCAAATTGCCCTACAACGTAACGGTGTTAATGGTCCCGTGCCGCCAACCACTGAGTTACAAGAGGTCCGTGAAC AGTATCCTAAGCTGTATTCGGCGGTGGTGCGCGGCTTCGCAACGATTTTTAAAGACCAGGATTTTACAACTGATGAGTTG ACGTACTTGTTGATTCACTTTGCTAGTACGTATGAGCAACAGTTGAGTCACCAAGCACTCAAGGTTTTGGTCCTGTGCCC GAATGGGATGACGACGGCGCGAATTTTGAAAACGCGACTGATGCGGTTAGTACCTGAAATCACGGCTATCGAGGTTGCGC GGATTGGTAATTTAGGCCAAGTTAATTTACAAGACTTTGACATGATTTTATCCACGACAACGTTACCGGGATTTAAGTTG AATTACCGCGTTGTCAGCCCACTGTTACTAGAAAACGAAGTCACTGCCTTACGGGAATATATTCATCAGTATTTTCCAAG CACCAAAGTGATCGATTCACCGGTTGATGAGCCGACGAAAATCAACTTGGATTTTGACACCGTTTACCAACAAATGACGA TTGCTAAACAGATCTTAGACCGTTTCACTATCACGCCGATTCGCAACGATGATGAGACGGTGGCCGAGATGCTAGTTAAG ATCACGCGGCATATTGATTCGAACTTGATTCATGATCCGCTAGAAGTTGCGGGCCGGTTGTTACACCGCTTAGGACTGGC GCCGGTCGGTATTCCCAATACGAACTTGGCGTTGGTGCATACGTTAAGTCAGGAAGTCACCGCACCATATTGTGCGATTT TCGAACTTGACCAGCCATTACCATTTAAGAGTATGGACAACCAATCGATTCGGTTGCAGCGAATCGTCCTAATGCTCGGG CCCGCCAATATCAGCGATTTTGAAAATCGGTTGATGGGTAAGTTAAGCGCGCTAGTCATTGAAAGTCAGGCCAATACGCA GACGTTTATGACTGGCGATCGCCAGCAACTTTATCAATTAATTAGTAAAGCATTTTTGAACGAACTAACGAAATAG
Upstream 100 bases:
>100_bases ATTAATTACTGACGATCTATTGAGTTCACCTAAATATGATAAGATGGTATCAGAATTGAAATAAAATGATATTATTACCA TTATCGTATGAGGTGGCATC
Downstream 100 bases:
>100_bases CGTAGGTGAAAACAATGGAAGCTTTAGATAAGAAAATGATTGCGTTGAACCAGCAAGTGGCTACGCAAGAAGAAGGCATC CGCTTAGCCGGTCAACTATT
Product: transcription regulator, mannitol operon
Products: NA
Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]
Number of amino acids: Translated: 691; Mature: 691
Protein sequence:
>691_residues MVKFTQRQDELLQLLLANPAGLSMSQIETGLNSSRRTIYREFSNLELVLANADLKIVNEKHHFQLSGSQTALAKFQSQLT AERKIAPAFDSQTRQNALACRLLMTGHSVKLKELALDFDVSVATISNDLTALATPFADYDLSIERLKSRGIQVAGTEGSI RNLFATILNNEINDYEFFKTIGKLNQGLAISASDEQSYFLNLLDAQTLIICYQAVRSLKKKYFSSVPDGQLQQLIITLTT GVMRLQHERRVTYLRGINRDDFLKYQRIALAIMTQLPAEIKTVVTGAEIDFLAQQIKGLTFRIDQDASLSNYDLQLTYRV KKFIDAVATNFNWSFGTDDRLLNNLTAHMQIALQRNGVNGPVPPTTELQEVREQYPKLYSAVVRGFATIFKDQDFTTDEL TYLLIHFASTYEQQLSHQALKVLVLCPNGMTTARILKTRLMRLVPEITAIEVARIGNLGQVNLQDFDMILSTTTLPGFKL NYRVVSPLLLENEVTALREYIHQYFPSTKVIDSPVDEPTKINLDFDTVYQQMTIAKQILDRFTITPIRNDDETVAEMLVK ITRHIDSNLIHDPLEVAGRLLHRLGLAPVGIPNTNLALVHTLSQEVTAPYCAIFELDQPLPFKSMDNQSIRLQRIVLMLG PANISDFENRLMGKLSALVIESQANTQTFMTGDRQQLYQLISKAFLNELTK
Sequences:
>Translated_691_residues MVKFTQRQDELLQLLLANPAGLSMSQIETGLNSSRRTIYREFSNLELVLANADLKIVNEKHHFQLSGSQTALAKFQSQLT AERKIAPAFDSQTRQNALACRLLMTGHSVKLKELALDFDVSVATISNDLTALATPFADYDLSIERLKSRGIQVAGTEGSI RNLFATILNNEINDYEFFKTIGKLNQGLAISASDEQSYFLNLLDAQTLIICYQAVRSLKKKYFSSVPDGQLQQLIITLTT GVMRLQHERRVTYLRGINRDDFLKYQRIALAIMTQLPAEIKTVVTGAEIDFLAQQIKGLTFRIDQDASLSNYDLQLTYRV KKFIDAVATNFNWSFGTDDRLLNNLTAHMQIALQRNGVNGPVPPTTELQEVREQYPKLYSAVVRGFATIFKDQDFTTDEL TYLLIHFASTYEQQLSHQALKVLVLCPNGMTTARILKTRLMRLVPEITAIEVARIGNLGQVNLQDFDMILSTTTLPGFKL NYRVVSPLLLENEVTALREYIHQYFPSTKVIDSPVDEPTKINLDFDTVYQQMTIAKQILDRFTITPIRNDDETVAEMLVK ITRHIDSNLIHDPLEVAGRLLHRLGLAPVGIPNTNLALVHTLSQEVTAPYCAIFELDQPLPFKSMDNQSIRLQRIVLMLG PANISDFENRLMGKLSALVIESQANTQTFMTGDRQQLYQLISKAFLNELTK >Mature_691_residues MVKFTQRQDELLQLLLANPAGLSMSQIETGLNSSRRTIYREFSNLELVLANADLKIVNEKHHFQLSGSQTALAKFQSQLT AERKIAPAFDSQTRQNALACRLLMTGHSVKLKELALDFDVSVATISNDLTALATPFADYDLSIERLKSRGIQVAGTEGSI RNLFATILNNEINDYEFFKTIGKLNQGLAISASDEQSYFLNLLDAQTLIICYQAVRSLKKKYFSSVPDGQLQQLIITLTT GVMRLQHERRVTYLRGINRDDFLKYQRIALAIMTQLPAEIKTVVTGAEIDFLAQQIKGLTFRIDQDASLSNYDLQLTYRV KKFIDAVATNFNWSFGTDDRLLNNLTAHMQIALQRNGVNGPVPPTTELQEVREQYPKLYSAVVRGFATIFKDQDFTTDEL TYLLIHFASTYEQQLSHQALKVLVLCPNGMTTARILKTRLMRLVPEITAIEVARIGNLGQVNLQDFDMILSTTTLPGFKL NYRVVSPLLLENEVTALREYIHQYFPSTKVIDSPVDEPTKINLDFDTVYQQMTIAKQILDRFTITPIRNDDETVAEMLVK ITRHIDSNLIHDPLEVAGRLLHRLGLAPVGIPNTNLALVHTLSQEVTAPYCAIFELDQPLPFKSMDNQSIRLQRIVLMLG PANISDFENRLMGKLSALVIESQANTQTFMTGDRQQLYQLISKAFLNELTK
Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]
COG id: COG3711
COG function: function code K; Transcriptional antiterminator
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIB type-2 domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013196 - InterPro: IPR007737 - InterPro: IPR011608 - InterPro: IPR016152 - InterPro: IPR002178 - InterPro: IPR013011 - InterPro: IPR003501 - InterPro: IPR011991 [H]
Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 78022; Mature: 78022
Theoretical pI: Translated: 6.80; Mature: 6.80
Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVKFTQRQDELLQLLLANPAGLSMSQIETGLNSSRRTIYREFSNLELVLANADLKIVNEK CCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHCCCEEEEECCCEEEECCC HHFQLSGSQTALAKFQSQLTAERKIAPAFDSQTRQNALACRLLMTGHSVKLKELALDFDV CEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHEECCC SVATISNDLTALATPFADYDLSIERLKSRGIQVAGTEGSIRNLFATILNNEINDYEFFKT EEEEECCCHHHHCCCCCCCCCHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHH IGKLNQGLAISASDEQSYFLNLLDAQTLIICYQAVRSLKKKYFSSVPDGQLQQLIITLTT HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH GVMRLQHERRVTYLRGINRDDFLKYQRIALAIMTQLPAEIKTVVTGAEIDFLAQQIKGLT HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCE FRIDQDASLSNYDLQLTYRVKKFIDAVATNFNWSFGTDDRLLNNLTAHMQIALQRNGVNG EEECCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCC PVPPTTELQEVREQYPKLYSAVVRGFATIFKDQDFTTDELTYLLIHFASTYEQQLSHQAL CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHE KVLVLCPNGMTTARILKTRLMRLVPEITAIEVARIGNLGQVNLQDFDMILSTTTLPGFKL EEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEE NYRVVSPLLLENEVTALREYIHQYFPSTKVIDSPVDEPTKINLDFDTVYQQMTIAKQILD EHEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHH RFTITPIRNDDETVAEMLVKITRHIDSNLIHDPLEVAGRLLHRLGLAPVGIPNTNLALVH HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEE TLSQEVTAPYCAIFELDQPLPFKSMDNQSIRLQRIVLMLGPANISDFENRLMGKLSALVI EHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHEE ESQANTQTFMTGDRQQLYQLISKAFLNELTK ECCCCCCCEECCCHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MVKFTQRQDELLQLLLANPAGLSMSQIETGLNSSRRTIYREFSNLELVLANADLKIVNEK CCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHCCCEEEEECCCEEEECCC HHFQLSGSQTALAKFQSQLTAERKIAPAFDSQTRQNALACRLLMTGHSVKLKELALDFDV CEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHEECCC SVATISNDLTALATPFADYDLSIERLKSRGIQVAGTEGSIRNLFATILNNEINDYEFFKT EEEEECCCHHHHCCCCCCCCCHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHH IGKLNQGLAISASDEQSYFLNLLDAQTLIICYQAVRSLKKKYFSSVPDGQLQQLIITLTT HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH GVMRLQHERRVTYLRGINRDDFLKYQRIALAIMTQLPAEIKTVVTGAEIDFLAQQIKGLT HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCE FRIDQDASLSNYDLQLTYRVKKFIDAVATNFNWSFGTDDRLLNNLTAHMQIALQRNGVNG EEECCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCC PVPPTTELQEVREQYPKLYSAVVRGFATIFKDQDFTTDELTYLLIHFASTYEQQLSHQAL CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHE KVLVLCPNGMTTARILKTRLMRLVPEITAIEVARIGNLGQVNLQDFDMILSTTTLPGFKL EEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEE NYRVVSPLLLENEVTALREYIHQYFPSTKVIDSPVDEPTKINLDFDTVYQQMTIAKQILD EHEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHH RFTITPIRNDDETVAEMLVKITRHIDSNLIHDPLEVAGRLLHRLGLAPVGIPNTNLALVH HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEE TLSQEVTAPYCAIFELDQPLPFKSMDNQSIRLQRIVLMLGPANISDFENRLMGKLSALVI EHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHEE ESQANTQTFMTGDRQQLYQLISKAFLNELTK ECCCCCCCEECCCHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]