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The map label for this gene is agl3 [H]

Identifier: 28377131

GI number: 28377131

Start: 175091

End: 176764

Strand: Direct

Name: agl3 [H]

Synonym: lp_0193

Alternate gene names: 28377131

Gene position: 175091-176764 (Clockwise)

Preceding gene: 28377128

Following gene: 28377133

Centisome position: 5.29

GC content: 46.95

Gene sequence:

>1674_bases
ATGGCTAATCAATGGTGGCAATCAGCGGTTGTTTATCAGGTTTATCCACGGTCGTTTCAGGATTCAAATGGTGATGGAAT
CGGTGATTTGCCAGGAATTACACAACGGTTAGATTATATTAAACAGCTCGGCGCGGATGTGATTTGGCTCAACCCAATTT
ACCGTTCACCCGGTGTCGATAATGGCTATGATATTAGTGATTATTACGATATTAATCCAGAATTCGGGACGATGGCTGAT
TTTGATCAATTATTAACAACGGCCCATGCGAAAGGGTTAAAAATCATGATGGACATTGTTGTCAACCATTCATCTGATCA
AAATAAGTGGTTTACGACGAGTGCGCAAAGTAAGGATAATCCGTACGCGGACTATTATATTTGGCGTGATCCTGTTGATG
GGCATGAACCTAACAACTGGGGTGGCTTTTTCGGTGGCTCTGCTTGGAAATATGTTGCCAGCCGTGATCAGTATTACTTA
CATTCATTTGCGGTTGAACAGCCAGATTTGAACTGGGATAATCCGCAACTACGGCAAGCAGTCTATGACATGATGAATTT
CTGGGTCAATAAGGGCGTGGACGGTTTCCGCTTGGATGTCATTAACTTGATTTCCAAGCCTGATAGCTTTGCAGATGGGC
AGCCAGAAGCTGGGGAACCATACGCGGCAATCGGTGGAATTATTGCCAATGGTCCGCATCTCCATGAATACTTACAAGAA
ATGAATCAGCAAGTGTTTGCAGGCCATCAACTGATGACGGTCGGCGAAACGCCTGGGGCTACGGTTGCTGATGCTAAGCA
ACTGGCAAGCGGCCAAGGTCAGGAATTAAACATGGTGTTTGAATTTGAACACATGGGCCTGGATGGTAATCCAGATCCGG
CGCTAGGTAAGTGGAATGACCAGCCCGTCCGACTGGTTGACCTAAAGCAGAGCTTGTCTAAGTGGCAAATGGGCTTACAA
GGGACAGCCTGGAATAGTCTCTATTGGAATAATCATGACCAACCGCGAATTGTGTCACGATTCGGGGATGAACGGCCAGC
TTATCGGGAACGTTCAGCCAAAATGCTAGCGACCCTATTGCACTTTCTTCAAGGGACACCCTACATCTACGAAGGTGAGG
AGCTAGGCATGACGAATGCCCATTTTACCAAGTTAACCGACTATCAAGACTTGGAATCACTGAATGCGTATCATCACTTT
GTTGATGACGAACAGGTCGTTCAACCTGAACAGATGTTAGGTTATCTCGCCCATATGTCGCGGGATAATGCGCGTACACC
GATGCAGTGGGATGATAGTCAGAATGCTGGGTTTTCAACGGCAACACCGTGGCTAGCGGTTAATGCCAATTATCCGCGGA
TCAACGCGCAACTCGCGCAACGAACGCCCGGTTCAGTTCTGAGCTATTATCAGCGGCTGATTAAGCTCCGGCACCATTTA
CCAGTCATAACGACGGGAACTTATCACCTATTATCACCTGATGATGCGGCCGTTTATGCCTATGTGCGGCATATGGGGTC
GCAGCACCTGCTAGTAATTTGTAACTTTACTGCGGCAACCCAGACGCGACACTTTGCAGAATTACCCGCTGATGCGCATC
TGTTGATCAGTAACTACGATGAAGATCATCAAGACGTATTACGAGCGTACGAAGCGAAAGTTTACCAGTTTTAG

Upstream 100 bases:

>100_bases
TGACCGACAATGGTAGAATGGTTAGTGTTGTAAGCGGTACCTTTTATGGTTGACCGTGACAAGTTTTTTAAAGCAAACTT
TTTTAGGGGGATAATCATAT

Downstream 100 bases:

>100_bases
GTCACAATTAGCTTCGCTGCTGGAGTTGTGAATGTGATTTTTAACGGCGGTTGTGTGATTACGAGCACGAGTTGGTCGTG
TAAATTTAATCGTGATGACT

Product: alpha-glucosidase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MANQWWQSAVVYQVYPRSFQDSNGDGIGDLPGITQRLDYIKQLGADVIWLNPIYRSPGVDNGYDISDYYDINPEFGTMAD
FDQLLTTAHAKGLKIMMDIVVNHSSDQNKWFTTSAQSKDNPYADYYIWRDPVDGHEPNNWGGFFGGSAWKYVASRDQYYL
HSFAVEQPDLNWDNPQLRQAVYDMMNFWVNKGVDGFRLDVINLISKPDSFADGQPEAGEPYAAIGGIIANGPHLHEYLQE
MNQQVFAGHQLMTVGETPGATVADAKQLASGQGQELNMVFEFEHMGLDGNPDPALGKWNDQPVRLVDLKQSLSKWQMGLQ
GTAWNSLYWNNHDQPRIVSRFGDERPAYRERSAKMLATLLHFLQGTPYIYEGEELGMTNAHFTKLTDYQDLESLNAYHHF
VDDEQVVQPEQMLGYLAHMSRDNARTPMQWDDSQNAGFSTATPWLAVNANYPRINAQLAQRTPGSVLSYYQRLIKLRHHL
PVITTGTYHLLSPDDAAVYAYVRHMGSQHLLVICNFTAATQTRHFAELPADAHLLISNYDEDHQDVLRAYEAKVYQF

Sequences:

>Translated_557_residues
MANQWWQSAVVYQVYPRSFQDSNGDGIGDLPGITQRLDYIKQLGADVIWLNPIYRSPGVDNGYDISDYYDINPEFGTMAD
FDQLLTTAHAKGLKIMMDIVVNHSSDQNKWFTTSAQSKDNPYADYYIWRDPVDGHEPNNWGGFFGGSAWKYVASRDQYYL
HSFAVEQPDLNWDNPQLRQAVYDMMNFWVNKGVDGFRLDVINLISKPDSFADGQPEAGEPYAAIGGIIANGPHLHEYLQE
MNQQVFAGHQLMTVGETPGATVADAKQLASGQGQELNMVFEFEHMGLDGNPDPALGKWNDQPVRLVDLKQSLSKWQMGLQ
GTAWNSLYWNNHDQPRIVSRFGDERPAYRERSAKMLATLLHFLQGTPYIYEGEELGMTNAHFTKLTDYQDLESLNAYHHF
VDDEQVVQPEQMLGYLAHMSRDNARTPMQWDDSQNAGFSTATPWLAVNANYPRINAQLAQRTPGSVLSYYQRLIKLRHHL
PVITTGTYHLLSPDDAAVYAYVRHMGSQHLLVICNFTAATQTRHFAELPADAHLLISNYDEDHQDVLRAYEAKVYQF
>Mature_556_residues
ANQWWQSAVVYQVYPRSFQDSNGDGIGDLPGITQRLDYIKQLGADVIWLNPIYRSPGVDNGYDISDYYDINPEFGTMADF
DQLLTTAHAKGLKIMMDIVVNHSSDQNKWFTTSAQSKDNPYADYYIWRDPVDGHEPNNWGGFFGGSAWKYVASRDQYYLH
SFAVEQPDLNWDNPQLRQAVYDMMNFWVNKGVDGFRLDVINLISKPDSFADGQPEAGEPYAAIGGIIANGPHLHEYLQEM
NQQVFAGHQLMTVGETPGATVADAKQLASGQGQELNMVFEFEHMGLDGNPDPALGKWNDQPVRLVDLKQSLSKWQMGLQG
TAWNSLYWNNHDQPRIVSRFGDERPAYRERSAKMLATLLHFLQGTPYIYEGEELGMTNAHFTKLTDYQDLESLNAYHHFV
DDEQVVQPEQMLGYLAHMSRDNARTPMQWDDSQNAGFSTATPWLAVNANYPRINAQLAQRTPGSVLSYYQRLIKLRHHLP
VITTGTYHLLSPDDAAVYAYVRHMGSQHLLVICNFTAATQTRHFAELPADAHLLISNYDEDHQDVLRAYEAKVYQF

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=564, Percent_Identity=30.3191489361702, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI65506891, Length=112, Percent_Identity=33.0357142857143, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI61744475, Length=112, Percent_Identity=33.0357142857143, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI61744479, Length=112, Percent_Identity=33.0357142857143, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI61744477, Length=112, Percent_Identity=33.0357142857143, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI61744483, Length=112, Percent_Identity=33.0357142857143, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI61744481, Length=112, Percent_Identity=33.0357142857143, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1790687, Length=537, Percent_Identity=46.5549348230913, Blast_Score=507, Evalue=1e-145,
Organism=Escherichia coli, GI1786604, Length=374, Percent_Identity=24.331550802139, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789995, Length=244, Percent_Identity=23.3606557377049, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=492, Percent_Identity=27.0325203252033, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32565753, Length=382, Percent_Identity=23.8219895287958, Blast_Score=112, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6322245, Length=574, Percent_Identity=37.2822299651568, Blast_Score=396, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321726, Length=578, Percent_Identity=36.5051903114187, Blast_Score=378, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6324416, Length=578, Percent_Identity=36.3321799307958, Blast_Score=366, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6322241, Length=578, Percent_Identity=36.159169550173, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6322021, Length=578, Percent_Identity=36.159169550173, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6319776, Length=580, Percent_Identity=35.3448275862069, Blast_Score=351, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6321731, Length=580, Percent_Identity=35.1724137931034, Blast_Score=350, Evalue=5e-97,
Organism=Drosophila melanogaster, GI24583745, Length=572, Percent_Identity=37.4125874125874, Blast_Score=311, Evalue=6e-85,
Organism=Drosophila melanogaster, GI221330053, Length=499, Percent_Identity=37.0741482965932, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24583747, Length=568, Percent_Identity=35.387323943662, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24583749, Length=568, Percent_Identity=35.7394366197183, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI45549022, Length=575, Percent_Identity=33.3913043478261, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24586597, Length=555, Percent_Identity=34.5945945945946, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI24586593, Length=559, Percent_Identity=32.737030411449, Blast_Score=277, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24586599, Length=580, Percent_Identity=31.551724137931, Blast_Score=275, Evalue=5e-74,
Organism=Drosophila melanogaster, GI24586587, Length=499, Percent_Identity=32.8657314629259, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24586589, Length=500, Percent_Identity=33.2, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24586591, Length=542, Percent_Identity=32.4723247232472, Blast_Score=248, Evalue=7e-66,
Organism=Drosophila melanogaster, GI281360393, Length=503, Percent_Identity=29.8210735586481, Blast_Score=201, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 63343; Mature: 63212

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANQWWQSAVVYQVYPRSFQDSNGDGIGDLPGITQRLDYIKQLGADVIWLNPIYRSPGVD
CCCHHHHHCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCHHCCCCCC
NGYDISDYYDINPEFGTMADFDQLLTTAHAKGLKIMMDIVVNHSSDQNKWFTTSAQSKDN
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCHHEEEEHHHCCCCCCCCEEEECCCCCCC
PYADYYIWRDPVDGHEPNNWGGFFGGSAWKYVASRDQYYLHSFAVEQPDLNWDNPQLRQA
CCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEHHEEECCCCCCCCCHHHHHH
VYDMMNFWVNKGVDGFRLDVINLISKPDSFADGQPEAGEPYAAIGGIIANGPHLHEYLQE
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCHHCCCHHHHHHHHH
MNQQVFAGHQLMTVGETPGATVADAKQLASGQGQELNMVFEFEHMGLDGNPDPALGKWND
HHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCC
QPVRLVDLKQSLSKWQMGLQGTAWNSLYWNNHDQPRIVSRFGDERPAYRERSAKMLATLL
CCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
HFLQGTPYIYEGEELGMTNAHFTKLTDYQDLESLNAYHHFVDDEQVVQPEQMLGYLAHMS
HHHCCCCEEECCHHCCCCCCCCEECCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHC
RDNARTPMQWDDSQNAGFSTATPWLAVNANYPRINAQLAQRTPGSVLSYYQRLIKLRHHL
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCC
PVITTGTYHLLSPDDAAVYAYVRHMGSQHLLVICNFTAATQTRHFAELPADAHLLISNYD
CEEECCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHCCCCCEEEEECCC
EDHQDVLRAYEAKVYQF
CHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANQWWQSAVVYQVYPRSFQDSNGDGIGDLPGITQRLDYIKQLGADVIWLNPIYRSPGVD
CCHHHHHCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCHHCCCCCC
NGYDISDYYDINPEFGTMADFDQLLTTAHAKGLKIMMDIVVNHSSDQNKWFTTSAQSKDN
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCHHEEEEHHHCCCCCCCCEEEECCCCCCC
PYADYYIWRDPVDGHEPNNWGGFFGGSAWKYVASRDQYYLHSFAVEQPDLNWDNPQLRQA
CCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEHHEEECCCCCCCCCHHHHHH
VYDMMNFWVNKGVDGFRLDVINLISKPDSFADGQPEAGEPYAAIGGIIANGPHLHEYLQE
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCHHCCCHHHHHHHHH
MNQQVFAGHQLMTVGETPGATVADAKQLASGQGQELNMVFEFEHMGLDGNPDPALGKWND
HHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCC
QPVRLVDLKQSLSKWQMGLQGTAWNSLYWNNHDQPRIVSRFGDERPAYRERSAKMLATLL
CCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHH
HFLQGTPYIYEGEELGMTNAHFTKLTDYQDLESLNAYHHFVDDEQVVQPEQMLGYLAHMS
HHHCCCCEEECCHHCCCCCCCCEECCCHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHC
RDNARTPMQWDDSQNAGFSTATPWLAVNANYPRINAQLAQRTPGSVLSYYQRLIKLRHHL
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCC
PVITTGTYHLLSPDDAAVYAYVRHMGSQHLLVICNFTAATQTRHFAELPADAHLLISNYD
CEEECCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHCCCCCEEEEECCC
EDHQDVLRAYEAKVYQF
CHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]