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The map label for this gene is agl2 [H]

Identifier: 28377128

GI number: 28377128

Start: 170177

End: 171853

Strand: Direct

Name: agl2 [H]

Synonym: lp_0189

Alternate gene names: 28377128

Gene position: 170177-171853 (Clockwise)

Preceding gene: 28377127

Following gene: 28377131

Centisome position: 5.14

GC content: 47.7

Gene sequence:

>1677_bases
ATGGCAGCAACAATCAAGTGGTGGCAACAAGCCGTTGTCTATCAGGTCTATCCACGGAGTTTTCAAGATACCAATCATGA
TGGTATTGGTGACTTAAAGGGGATCACGGCCCACCTAGACTACTTAAAGCAATTAGGAATCGACGTCATTTGGCTCAATC
CCATTTATCGTTCACCCAACGATGATAATGGTTATGATATTAGTGATTATCAACAAATTGCGGCCGACTTTGGCACTATG
GCTGATTTTGATGAATTATTGCAAGCCGCCCATGACCGGGGCTTAAAGATCATCATGGACTTGGTTGTTAACCATACCTC
TGATGAGCATCCATGGTTCAAACGCAGTCGCCAGGACCGCACCAATCAATATCGTGATTTCTACTTTTGGCGCTCAGGTA
ACGGCAAAAAGGCGCCCAATAATTGGGATGCGGCTTTTGGTGGTTCAGCATGGCAATATGATGAGCAGACCCAGCAGTAT
TATTTACACACGTTTTCAACAAAACAACCTGATTTAAACTGGGAGAATCCGACCTTACGAGAGTCAGTTTATACGATGAT
GACCTGGTGGCTGAACAAGGGTGTTGACGGTTTTCGAATGGACGTCATTAACCAAATCTCTAAGTTACCCGGGTTACCAG
ATGGTCCACTGAAACCGCACAGTCAGTTTGGCGATGCTCGAGTAACGAACGGACCGCGAGTTCATGAATTCTTGCAAGAA
ATGAACCAAGAAGTGTTGTCACAGTTTGATATCATGACGGTTGGTGAGACCCACGGGGTGACACCAGCGGATGCGCTGAA
GTATGCGGGCGCTGATCGGCACGAATTAGATATGGTCTTTGAATTTCAACATCTGCGACTTGATAATAGTCAGCATGGTC
TTGGTAAGTGGAGTACGCGTAAGACACCGTTAGTGGCGCTAAAGAAAGTCATTAGTGACTGGCAAGTCGGACTTGAAGGG
CGGGCTTGGAACAGCCTGTTTTGGAACAATCATGATACGCCACGAGCGGTCTCACGTTTTGGTGATGACCGACCAGCATA
TCGGGTACGTTCGGCTAAAATGCTCGCAACGTGTTTACACATCTTGCAGGGAACCCCGTATATTTATCAAGGTGAAGAAC
TGGGGATGACTGACGCTCATTTTACTGAATTAACCAGTTACCGGGATATTGAATCGCTCAATGCCTATCGTGATTTAGTG
ACTGAGCGCCAACTACTATCACCGGCAGATATGATGGCCCGATTAGCGGCGCGTTCTCGGGACAACTCGCGAACGCCGAT
GCAATGGGACACGGAGGTTAACGCGGGTTTTAGTGACGCGGCGCCATGGCTCACGGTCAATCCCAACTATCGTCAAATCA
ATGCTGCCGCAGCTTTGGCTGATCCGGATTCAGTGTGGTACTATTACCAGCACTTGATTCAATTACGACATCAATACCCC
TTAGTGACGTTAGGTTCGTTTGAGCTCTTGTGGGCTGATGATCCGCAGGTATTCTTATATGCACGGCAATGGGAAGGGCG
AACCTGGCTAGTTTGTTGCAATTTCACAGCCGAGACACTGTCCCGACCACTGGATCAATATCTGACGCCCACGGCCAAAT
GCTTGATTAGTAATTATGGCGAGCAGCAGCCAAATAAATTACGGCCTTATGAGGCTTGGGTCTACCAACTCGCATAG

Upstream 100 bases:

>100_bases
AGCGGATTGAGGATGCGAATTGTACACTGGAATCAAAATATACGTTACCAGTTAAGCTCATCAAGGGCCTTACCGCGTAA
CTAAGGAGTTAATCGTAATT

Downstream 100 bases:

>100_bases
GTATCCAGGACTTGGCTAATTGAGGCGGTCTTTGAAATATACCCAATCGTTACGATTAGTGTGAATTGGGTTGCTTAAAA
TTCTGCGATGGTCTTAATAA

Product: alpha-glucosidase

Products: NA

Alternate protein names: Maltase [H]

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MAATIKWWQQAVVYQVYPRSFQDTNHDGIGDLKGITAHLDYLKQLGIDVIWLNPIYRSPNDDNGYDISDYQQIAADFGTM
ADFDELLQAAHDRGLKIIMDLVVNHTSDEHPWFKRSRQDRTNQYRDFYFWRSGNGKKAPNNWDAAFGGSAWQYDEQTQQY
YLHTFSTKQPDLNWENPTLRESVYTMMTWWLNKGVDGFRMDVINQISKLPGLPDGPLKPHSQFGDARVTNGPRVHEFLQE
MNQEVLSQFDIMTVGETHGVTPADALKYAGADRHELDMVFEFQHLRLDNSQHGLGKWSTRKTPLVALKKVISDWQVGLEG
RAWNSLFWNNHDTPRAVSRFGDDRPAYRVRSAKMLATCLHILQGTPYIYQGEELGMTDAHFTELTSYRDIESLNAYRDLV
TERQLLSPADMMARLAARSRDNSRTPMQWDTEVNAGFSDAAPWLTVNPNYRQINAAAALADPDSVWYYYQHLIQLRHQYP
LVTLGSFELLWADDPQVFLYARQWEGRTWLVCCNFTAETLSRPLDQYLTPTAKCLISNYGEQQPNKLRPYEAWVYQLA

Sequences:

>Translated_558_residues
MAATIKWWQQAVVYQVYPRSFQDTNHDGIGDLKGITAHLDYLKQLGIDVIWLNPIYRSPNDDNGYDISDYQQIAADFGTM
ADFDELLQAAHDRGLKIIMDLVVNHTSDEHPWFKRSRQDRTNQYRDFYFWRSGNGKKAPNNWDAAFGGSAWQYDEQTQQY
YLHTFSTKQPDLNWENPTLRESVYTMMTWWLNKGVDGFRMDVINQISKLPGLPDGPLKPHSQFGDARVTNGPRVHEFLQE
MNQEVLSQFDIMTVGETHGVTPADALKYAGADRHELDMVFEFQHLRLDNSQHGLGKWSTRKTPLVALKKVISDWQVGLEG
RAWNSLFWNNHDTPRAVSRFGDDRPAYRVRSAKMLATCLHILQGTPYIYQGEELGMTDAHFTELTSYRDIESLNAYRDLV
TERQLLSPADMMARLAARSRDNSRTPMQWDTEVNAGFSDAAPWLTVNPNYRQINAAAALADPDSVWYYYQHLIQLRHQYP
LVTLGSFELLWADDPQVFLYARQWEGRTWLVCCNFTAETLSRPLDQYLTPTAKCLISNYGEQQPNKLRPYEAWVYQLA
>Mature_557_residues
AATIKWWQQAVVYQVYPRSFQDTNHDGIGDLKGITAHLDYLKQLGIDVIWLNPIYRSPNDDNGYDISDYQQIAADFGTMA
DFDELLQAAHDRGLKIIMDLVVNHTSDEHPWFKRSRQDRTNQYRDFYFWRSGNGKKAPNNWDAAFGGSAWQYDEQTQQYY
LHTFSTKQPDLNWENPTLRESVYTMMTWWLNKGVDGFRMDVINQISKLPGLPDGPLKPHSQFGDARVTNGPRVHEFLQEM
NQEVLSQFDIMTVGETHGVTPADALKYAGADRHELDMVFEFQHLRLDNSQHGLGKWSTRKTPLVALKKVISDWQVGLEGR
AWNSLFWNNHDTPRAVSRFGDDRPAYRVRSAKMLATCLHILQGTPYIYQGEELGMTDAHFTELTSYRDIESLNAYRDLVT
ERQLLSPADMMARLAARSRDNSRTPMQWDTEVNAGFSDAAPWLTVNPNYRQINAAAALADPDSVWYYYQHLIQLRHQYPL
VTLGSFELLWADDPQVFLYARQWEGRTWLVCCNFTAETLSRPLDQYLTPTAKCLISNYGEQQPNKLRPYEAWVYQLA

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=531, Percent_Identity=31.8267419962335, Blast_Score=265, Evalue=1e-70,
Organism=Homo sapiens, GI65506891, Length=126, Percent_Identity=32.5396825396825, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI61744475, Length=126, Percent_Identity=32.5396825396825, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI61744479, Length=126, Percent_Identity=32.5396825396825, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI61744477, Length=126, Percent_Identity=32.5396825396825, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI61744481, Length=126, Percent_Identity=32.5396825396825, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744483, Length=126, Percent_Identity=32.5396825396825, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790687, Length=558, Percent_Identity=47.6702508960573, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1786604, Length=189, Percent_Identity=27.5132275132275, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1789995, Length=132, Percent_Identity=29.5454545454545, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081873, Length=235, Percent_Identity=23.8297872340426, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=590, Percent_Identity=24.406779661017, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI32565753, Length=203, Percent_Identity=29.064039408867, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321726, Length=589, Percent_Identity=38.7096774193548, Blast_Score=414, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6322241, Length=585, Percent_Identity=38.974358974359, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6322021, Length=585, Percent_Identity=38.974358974359, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6324416, Length=585, Percent_Identity=38.974358974359, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6322245, Length=580, Percent_Identity=38.7931034482759, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6319776, Length=576, Percent_Identity=38.3680555555556, Blast_Score=385, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6321731, Length=576, Percent_Identity=38.1944444444444, Blast_Score=384, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24583745, Length=541, Percent_Identity=36.5988909426987, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI221330053, Length=500, Percent_Identity=36.6, Blast_Score=296, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24583747, Length=566, Percent_Identity=35.3356890459364, Blast_Score=291, Evalue=7e-79,
Organism=Drosophila melanogaster, GI24583749, Length=566, Percent_Identity=35.3356890459364, Blast_Score=291, Evalue=7e-79,
Organism=Drosophila melanogaster, GI24586589, Length=560, Percent_Identity=34.4642857142857, Blast_Score=277, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24586593, Length=535, Percent_Identity=34.7663551401869, Blast_Score=276, Evalue=3e-74,
Organism=Drosophila melanogaster, GI45549022, Length=579, Percent_Identity=31.6062176165803, Blast_Score=268, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24586591, Length=516, Percent_Identity=34.1085271317829, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24586597, Length=573, Percent_Identity=33.1588132635253, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24586599, Length=559, Percent_Identity=32.9159212880143, Blast_Score=254, Evalue=8e-68,
Organism=Drosophila melanogaster, GI24586587, Length=514, Percent_Identity=33.852140077821, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI281360393, Length=475, Percent_Identity=31.7894736842105, Blast_Score=199, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 64584; Mature: 64453

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATIKWWQQAVVYQVYPRSFQDTNHDGIGDLKGITAHLDYLKQLGIDVIWLNPIYRSPN
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCEECCCC
DDNGYDISDYQQIAADFGTMADFDELLQAAHDRGLKIIMDLVVNHTSDEHPWFKRSRQDR
CCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHH
TNQYRDFYFWRSGNGKKAPNNWDAAFGGSAWQYDEQTQQYYLHTFSTKQPDLNWENPTLR
HHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCCCCCCCCCHHH
ESVYTMMTWWLNKGVDGFRMDVINQISKLPGLPDGPLKPHSQFGDARVTNGPRVHEFLQE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
MNQEVLSQFDIMTVGETHGVTPADALKYAGADRHELDMVFEFQHLRLDNSQHGLGKWSTR
HHHHHHHHCCEEEECCCCCCCHHHHHHHCCCCCHHHHHEEEHHHHCCCCCCCCCCCCCCC
KTPLVALKKVISDWQVGLEGRAWNSLFWNNHDTPRAVSRFGDDRPAYRVRSAKMLATCLH
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
ILQGTPYIYQGEELGMTDAHFTELTSYRDIESLNAYRDLVTERQLLSPADMMARLAARSR
HHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
DNSRTPMQWDTEVNAGFSDAAPWLTVNPNYRQINAAAALADPDSVWYYYQHLIQLRHQYP
CCCCCCCEECCCCCCCCCCCCCEEEECCCCEEEEHHHEECCCHHHHHHHHHHHHHHHCCC
LVTLGSFELLWADDPQVFLYARQWEGRTWLVCCNFTAETLSRPLDQYLTPTAKCLISNYG
EEEECCEEEEECCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHCC
EQQPNKLRPYEAWVYQLA
CCCCCCCCCHHHHHEECC
>Mature Secondary Structure 
AATIKWWQQAVVYQVYPRSFQDTNHDGIGDLKGITAHLDYLKQLGIDVIWLNPIYRSPN
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCEECCCC
DDNGYDISDYQQIAADFGTMADFDELLQAAHDRGLKIIMDLVVNHTSDEHPWFKRSRQDR
CCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHH
TNQYRDFYFWRSGNGKKAPNNWDAAFGGSAWQYDEQTQQYYLHTFSTKQPDLNWENPTLR
HHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCCCCCCCCCHHH
ESVYTMMTWWLNKGVDGFRMDVINQISKLPGLPDGPLKPHSQFGDARVTNGPRVHEFLQE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
MNQEVLSQFDIMTVGETHGVTPADALKYAGADRHELDMVFEFQHLRLDNSQHGLGKWSTR
HHHHHHHHCCEEEECCCCCCCHHHHHHHCCCCCHHHHHEEEHHHHCCCCCCCCCCCCCCC
KTPLVALKKVISDWQVGLEGRAWNSLFWNNHDTPRAVSRFGDDRPAYRVRSAKMLATCLH
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
ILQGTPYIYQGEELGMTDAHFTELTSYRDIESLNAYRDLVTERQLLSPADMMARLAARSR
HHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
DNSRTPMQWDTEVNAGFSDAAPWLTVNPNYRQINAAAALADPDSVWYYYQHLIQLRHQYP
CCCCCCCEECCCCCCCCCCCCCEEEECCCCEEEEHHHEECCCHHHHHHHHHHHHHHHCCC
LVTLGSFELLWADDPQVFLYARQWEGRTWLVCCNFTAETLSRPLDQYLTPTAKCLISNYG
EEEECCEEEEECCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHCC
EQQPNKLRPYEAWVYQLA
CCCCCCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA