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The map label for this gene is fixB [H]

Identifier: 28377104

GI number: 28377104

Start: 140318

End: 141859

Strand: Direct

Name: fixB [H]

Synonym: lp_0163

Alternate gene names: 28377104

Gene position: 140318-141859 (Clockwise)

Preceding gene: 28377103

Following gene: 28377106

Centisome position: 4.24

GC content: 52.27

Gene sequence:

>1542_bases
ATGGAATTACATTTAACGGCACGACAGACGGGATTGTGGCAACGGTTGATGGCACTGGCACGTGAGCAATTGATGGGACT
CGCCATGCAGATGGAGTCGACTGGGAAAGTCGATCGACCGACACTGACAACGCTTGCCCAGCAATTGGCTTTGGACGATC
CACTACCAGATGACCGCCTGAGCCAACGGGTTTTGAGTACATTAGCGCTGGCGCAAAGTTCAGCTGGGCTCGCTATGAGT
TTTGCCAGTAGTTGGCAAGTTGAGGATGCAATATTAACGTTTGGAACCCCGCAACAACGCCAACGGTATTGTGCACAATC
AGGTGTTTTTGGACTCGCGGCATTACCGGAACAAGTCATGGCTAGTAGTACCGTCAAAGCAACGCCGGTAACAGCTGGCT
GGCAACTGTCCGGTGCGGTTAAAACGGTATTGAATGTTACACAGGCAACTGAGTATTTAGTTCTCGCACAGACACCACCG
AATGCTACAGGGGCCTTTGTTATTAGTGCTGATCAGCCAGGCGTCACGGTCAGCCAACCAATAACCCCTTTAGGGTTACA
CGGATTGACCATCGCGGATGTTCAACTCACCGATGTCCCGGTTACGGCCGCTGATCAAATCGGTCAATTGGGACAAGGAC
AACGAGTGATGCAACGGGCGCAAAGCTTGGGGCAATTATTTGCCGGGGCGATTACAGCGGGAATATGGCAACATGCCACA
GACCAGGCACGACAGTTAGCGCTGACAGAACAGCCGCCGTTAACTGCCTTGGCGCCAGCAATGGCGATTACGGCCGCCTT
ACAGACTAGTGTCTACAATGCGGCCCAACAGGCCGATGATGAGCGCCCATTTACAGACGCAGCGCAATTGGCGGCAATGT
TTGCCAGCCAAAATGCCTTGGCGCCGTTTAAAATTTTGATGCCATTGATCGGTGATCTAGCCTATACGCAACACTCGCCG
TTAAGTGCCTTGCAAAATGACGTGGCGACACTACCGTTGATTGTTGGCACGGATACGCAATTGGCGTTGACTTTTGCCAC
GACGAGCCTGAATGACGAAGTGGCCGATGTCCCGACAACGGGACCCCACACAGCTCCTGAGCACCTAGTCGTGGCCGACC
TACATCGGGTCGTAAAACGCTTGAATTTGACTAGGGATGTGCCAGTCAATGTCGGCAGTATTGCTACGGCGAAACGCGTC
GTGGCATTAGGTCGAGGCGCGATGGAACCGGCAGTATTGCTTCAAGCCCAACAATTGGCCAAGTGGATTGGTGCAGCATT
GGCTGTTACCCAGCCGCTAACGGCTATGGAACAATTTAGCATTGAGCAACAAATTGGTGCCTCAGCAGTGACGGTTGCAC
CAGAAGTCTTGATCAACATTGGCGTCGCTGGTGATGATGATTACTTGGCTGGCATGGCTGGTGCGCAACACGTTCTTTCT
GTGAATACGGATGAACAAGCGCCAATCTTCAAGCATTCACAACAAATTTTCGTGGGCGGTGCCGCTGAATTTTTGGCCGG
AATGGTGGCAGCATTAAATTAA

Upstream 100 bases:

>100_bases
CAGCGTTTAATAGTGATAATGTTTATTCGCTTTTTTCGTTAGCAGGCTAAAAATGTGGTAAGTTAGACTTAATAGATGAC
GGATGAAGTGAGGGATCGGA

Downstream 100 bases:

>100_bases
TACGAAGTCGAGTTCGGCACTGTTGGTAGGTCTGACGGGGTCGTATGACAATCAATTGTTTGCACAAAAACTAAGGGTCA
CAGCAATGTACTGTGGCCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MELHLTARQTGLWQRLMALAREQLMGLAMQMESTGKVDRPTLTTLAQQLALDDPLPDDRLSQRVLSTLALAQSSAGLAMS
FASSWQVEDAILTFGTPQQRQRYCAQSGVFGLAALPEQVMASSTVKATPVTAGWQLSGAVKTVLNVTQATEYLVLAQTPP
NATGAFVISADQPGVTVSQPITPLGLHGLTIADVQLTDVPVTAADQIGQLGQGQRVMQRAQSLGQLFAGAITAGIWQHAT
DQARQLALTEQPPLTALAPAMAITAALQTSVYNAAQQADDERPFTDAAQLAAMFASQNALAPFKILMPLIGDLAYTQHSP
LSALQNDVATLPLIVGTDTQLALTFATTSLNDEVADVPTTGPHTAPEHLVVADLHRVVKRLNLTRDVPVNVGSIATAKRV
VALGRGAMEPAVLLQAQQLAKWIGAALAVTQPLTAMEQFSIEQQIGASAVTVAPEVLINIGVAGDDDYLAGMAGAQHVLS
VNTDEQAPIFKHSQQIFVGGAAEFLAGMVAALN

Sequences:

>Translated_513_residues
MELHLTARQTGLWQRLMALAREQLMGLAMQMESTGKVDRPTLTTLAQQLALDDPLPDDRLSQRVLSTLALAQSSAGLAMS
FASSWQVEDAILTFGTPQQRQRYCAQSGVFGLAALPEQVMASSTVKATPVTAGWQLSGAVKTVLNVTQATEYLVLAQTPP
NATGAFVISADQPGVTVSQPITPLGLHGLTIADVQLTDVPVTAADQIGQLGQGQRVMQRAQSLGQLFAGAITAGIWQHAT
DQARQLALTEQPPLTALAPAMAITAALQTSVYNAAQQADDERPFTDAAQLAAMFASQNALAPFKILMPLIGDLAYTQHSP
LSALQNDVATLPLIVGTDTQLALTFATTSLNDEVADVPTTGPHTAPEHLVVADLHRVVKRLNLTRDVPVNVGSIATAKRV
VALGRGAMEPAVLLQAQQLAKWIGAALAVTQPLTAMEQFSIEQQIGASAVTVAPEVLINIGVAGDDDYLAGMAGAQHVLS
VNTDEQAPIFKHSQQIFVGGAAEFLAGMVAALN
>Mature_513_residues
MELHLTARQTGLWQRLMALAREQLMGLAMQMESTGKVDRPTLTTLAQQLALDDPLPDDRLSQRVLSTLALAQSSAGLAMS
FASSWQVEDAILTFGTPQQRQRYCAQSGVFGLAALPEQVMASSTVKATPVTAGWQLSGAVKTVLNVTQATEYLVLAQTPP
NATGAFVISADQPGVTVSQPITPLGLHGLTIADVQLTDVPVTAADQIGQLGQGQRVMQRAQSLGQLFAGAITAGIWQHAT
DQARQLALTEQPPLTALAPAMAITAALQTSVYNAAQQADDERPFTDAAQLAAMFASQNALAPFKILMPLIGDLAYTQHSP
LSALQNDVATLPLIVGTDTQLALTFATTSLNDEVADVPTTGPHTAPEHLVVADLHRVVKRLNLTRDVPVNVGSIATAKRV
VALGRGAMEPAVLLQAQQLAKWIGAALAVTQPLTAMEQFSIEQQIGASAVTVAPEVLINIGVAGDDDYLAGMAGAQHVLS
VNTDEQAPIFKHSQQIFVGGAAEFLAGMVAALN

Specific function: Required for anaerobic carnitine reduction. May bring reductant to CaiA [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=271, Percent_Identity=22.8782287822878, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1786226, Length=117, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787990, Length=165, Percent_Identity=25.4545454545455, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=268, Percent_Identity=24.6268656716418, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 53926; Mature: 53926

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELHLTARQTGLWQRLMALAREQLMGLAMQMESTGKVDRPTLTTLAQQLALDDPLPDDRL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHH
SQRVLSTLALAQSSAGLAMSFASSWQVEDAILTFGTPQQRQRYCAQSGVFGLAALPEQVM
HHHHHHHHHHHHCCCCEEEEHHCCCCCCHHEEECCCHHHHHHHHHHCCCCCHHHCHHHHH
ASSTVKATPVTAGWQLSGAVKTVLNVTQATEYLVLAQTPPNATGAFVISADQPGVTVSQP
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEECCCCCCCCCCC
ITPLGLHGLTIADVQLTDVPVTAADQIGQLGQGQRVMQRAQSLGQLFAGAITAGIWQHAT
CCCCCCCCEEEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQARQLALTEQPPLTALAPAMAITAALQTSVYNAAQQADDERPFTDAAQLAAMFASQNAL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
APFKILMPLIGDLAYTQHSPLSALQNDVATLPLIVGTDTQLALTFATTSLNDEVADVPTT
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCCEEEEEEEECCCCCCCCCCCCC
GPHTAPEHLVVADLHRVVKRLNLTRDVPVNVGSIATAKRVVALGRGAMEPAVLLQAQQLA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
KWIGAALAVTQPLTAMEQFSIEQQIGASAVTVAPEVLINIGVAGDDDYLAGMAGAQHVLS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHEEECCCCCCHHHHHHHCCCCEEE
VNTDEQAPIFKHSQQIFVGGAAEFLAGMVAALN
ECCCCCCCHHHCCCEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MELHLTARQTGLWQRLMALAREQLMGLAMQMESTGKVDRPTLTTLAQQLALDDPLPDDRL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHH
SQRVLSTLALAQSSAGLAMSFASSWQVEDAILTFGTPQQRQRYCAQSGVFGLAALPEQVM
HHHHHHHHHHHHCCCCEEEEHHCCCCCCHHEEECCCHHHHHHHHHHCCCCCHHHCHHHHH
ASSTVKATPVTAGWQLSGAVKTVLNVTQATEYLVLAQTPPNATGAFVISADQPGVTVSQP
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEECCCCCCCCCCC
ITPLGLHGLTIADVQLTDVPVTAADQIGQLGQGQRVMQRAQSLGQLFAGAITAGIWQHAT
CCCCCCCCEEEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQARQLALTEQPPLTALAPAMAITAALQTSVYNAAQQADDERPFTDAAQLAAMFASQNAL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
APFKILMPLIGDLAYTQHSPLSALQNDVATLPLIVGTDTQLALTFATTSLNDEVADVPTT
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCCEEEEEEEECCCCCCCCCCCCC
GPHTAPEHLVVADLHRVVKRLNLTRDVPVNVGSIATAKRVVALGRGAMEPAVLLQAQQLA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
KWIGAALAVTQPLTAMEQFSIEQQIGASAVTVAPEVLINIGVAGDDDYLAGMAGAQHVLS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHEEECCCCCCHHHHHHHCCCCEEE
VNTDEQAPIFKHSQQIFVGGAAEFLAGMVAALN
ECCCCCCCHHHCCCEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA