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The map label for this gene is glgC

Identifier: 28376993

GI number: 28376993

Start: 22993

End: 24132

Strand: Direct

Name: glgC

Synonym: lp_0021

Alternate gene names: 28376993

Gene position: 22993-24132 (Clockwise)

Preceding gene: 28376992

Following gene: 28376994

Centisome position: 0.7

GC content: 45.0

Gene sequence:

>1140_bases
ATGCAAGATGAAATGTTAGGGATTATTTTAGCGGGCGGTCAGGGCACCCGGCTTGGTAAGTTGACAAAGGATACGGCTAA
GCCCGCCGTGCCATTCGGCGGTCGTTACCGAATTATTGATTTTACACTCAGCAACTGTGCTAACTCGGGTGTGAATACTG
TTGGGGTTATCACGCAATATCAACCCCTAGAACTGAATGCACATATTGGTAGCGGTGCGAGCTGGGGCTTTGATAGCTTA
AATGGTGGGGTGACGGTTTTACAACCATACTCGTCTAGTGAAGGTGAGAAGTTCTTTCAAGGGACGGCGCACGCCATTTA
TCAAAATATCGAATATATTGATCAACAAGACCCCAAGTACCTGCTCGTCTTATCTGGCGATCATATTTATAAGATGGATT
ATGACGCTATGCTGAAATATCATCAGGAGAAGAAGGCTTCGTTGACCGTTGGGGTGATCCACGTGACTAACGAAGAAGCC
AAACGCTTTGGCATGATGAATACGGATGCGACGGATCGAATCATTGAGTTTGAGGAAAAACCGGAACATCCTAAGAGTGA
TAAAGCCTCGATGGGTATTTATATCTTCAATTGGCCGACTTTGCGGGATTACTTAGTTAAGAGTTATGCTACCGATAAGT
CACTTGAAGACTTTGGTAAAAATGTCATTCCATCATACTTAGCCAATAATGAATCCGTTTACGCTTATGCTTTTAAGGGT
TACTGGCGAGATGTTGGAACGATTAAGAGTCTGTGGCAAGCCAATATGGAATTCCTATCGCCCCATAACCGGTTAAATAT
CGGCGATCGTTACTGGCGGATTTACTCTAAAGCAGAGGTGCTACCACCGATGTTTTTGACGGAAACGAGCCAGGTCAATA
ATGCCATGGTCGTTGATAGTTGTTACGTTGCGGGCGAAATTGATCATTCAATCTTATCGCAACGCGTGTCAGTTGGGATG
GGTAGTCGCGTGGTTGACAGTATGATTATGCCCGGTGCAACGATTGGAAAAAATGTGGTGATTGACCACGCATTGATTGG
CGAAGATGCAGTGATTGGTGATGATGCCCAGATTATTGGTACGACTGATAAGATTGCAGTTGTTGGGTATCACGAAACGA
TGGGGGTGGAACAACCATGA

Upstream 100 bases:

>100_bases
GATAAGCCGTATCGGGGGCAACCAGCTAGTTTTACCGTGACCTTGCCGGCGATGGGTGCATTGTTGATTCGACCAGTTAA
AGTGATAGGGGGAGTTAAGC

Downstream 100 bases:

>100_bases
GACGTGAACAAGTGAGTGCCATTATTAATTTACTGGAACCAAGTGACGCGTTACAACCATTGACTGCAGTTCGGCCAGTT
GGAATGTTACCCTTTGGTGG

Product: glucose-1-phosphate adenylyltransferase

Products: NA

Alternate protein names: ADP-glucose pyrophosphorylase; ADPGlc PPase; ADP-glucose synthase

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MQDEMLGIILAGGQGTRLGKLTKDTAKPAVPFGGRYRIIDFTLSNCANSGVNTVGVITQYQPLELNAHIGSGASWGFDSL
NGGVTVLQPYSSSEGEKFFQGTAHAIYQNIEYIDQQDPKYLLVLSGDHIYKMDYDAMLKYHQEKKASLTVGVIHVTNEEA
KRFGMMNTDATDRIIEFEEKPEHPKSDKASMGIYIFNWPTLRDYLVKSYATDKSLEDFGKNVIPSYLANNESVYAYAFKG
YWRDVGTIKSLWQANMEFLSPHNRLNIGDRYWRIYSKAEVLPPMFLTETSQVNNAMVVDSCYVAGEIDHSILSQRVSVGM
GSRVVDSMIMPGATIGKNVVIDHALIGEDAVIGDDAQIIGTTDKIAVVGYHETMGVEQP

Sequences:

>Translated_379_residues
MQDEMLGIILAGGQGTRLGKLTKDTAKPAVPFGGRYRIIDFTLSNCANSGVNTVGVITQYQPLELNAHIGSGASWGFDSL
NGGVTVLQPYSSSEGEKFFQGTAHAIYQNIEYIDQQDPKYLLVLSGDHIYKMDYDAMLKYHQEKKASLTVGVIHVTNEEA
KRFGMMNTDATDRIIEFEEKPEHPKSDKASMGIYIFNWPTLRDYLVKSYATDKSLEDFGKNVIPSYLANNESVYAYAFKG
YWRDVGTIKSLWQANMEFLSPHNRLNIGDRYWRIYSKAEVLPPMFLTETSQVNNAMVVDSCYVAGEIDHSILSQRVSVGM
GSRVVDSMIMPGATIGKNVVIDHALIGEDAVIGDDAQIIGTTDKIAVVGYHETMGVEQP
>Mature_379_residues
MQDEMLGIILAGGQGTRLGKLTKDTAKPAVPFGGRYRIIDFTLSNCANSGVNTVGVITQYQPLELNAHIGSGASWGFDSL
NGGVTVLQPYSSSEGEKFFQGTAHAIYQNIEYIDQQDPKYLLVLSGDHIYKMDYDAMLKYHQEKKASLTVGVIHVTNEEA
KRFGMMNTDATDRIIEFEEKPEHPKSDKASMGIYIFNWPTLRDYLVKSYATDKSLEDFGKNVIPSYLANNESVYAYAFKG
YWRDVGTIKSLWQANMEFLSPHNRLNIGDRYWRIYSKAEVLPPMFLTETSQVNNAMVVDSCYVAGEIDHSILSQRVSVGM
GSRVVDSMIMPGATIGKNVVIDHALIGEDAVIGDDAQIIGTTDKIAVVGYHETMGVEQP

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG0448

COG function: function code G; ADP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family

Homologues:

Organism=Homo sapiens, GI11761621, Length=393, Percent_Identity=25.4452926208651, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI31881779, Length=374, Percent_Identity=23.7967914438503, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI45447090, Length=374, Percent_Identity=23.7967914438503, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI11761619, Length=256, Percent_Identity=27.34375, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789837, Length=382, Percent_Identity=39.5287958115183, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1788351, Length=264, Percent_Identity=28.7878787878788, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI133931050, Length=367, Percent_Identity=25.6130790190736, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320148, Length=370, Percent_Identity=24.0540540540541, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21355443, Length=364, Percent_Identity=24.4505494505494, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24644084, Length=364, Percent_Identity=24.4505494505494, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24653912, Length=387, Percent_Identity=21.4470284237726, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLGC_LACPL (Q890J0)

Other databases:

- EMBL:   AL935252
- RefSeq:   NP_783885.1
- ProteinModelPortal:   Q890J0
- SMR:   Q890J0
- GeneID:   1061258
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_0021
- NMPDR:   fig|220668.1.peg.19
- HOGENOM:   HBG703946
- OMA:   SQMVDAH
- ProtClustDB:   PRK05293
- BioCyc:   LPLA220668:LP_0021-MONOMER
- BRENDA:   2.7.7.27
- HAMAP:   MF_00624
- InterPro:   IPR005836
- InterPro:   IPR011831
- InterPro:   IPR023049
- InterPro:   IPR005835
- InterPro:   IPR011004
- TIGRFAMs:   TIGR02091

Pfam domain/function: PF00483 NTP_transferase; SSF51161 Trimer_LpxA_like

EC number: =2.7.7.27

Molecular weight: Translated: 42044; Mature: 42044

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00808 ADP_GLC_PYROPHOSPH_1; PS00809 ADP_GLC_PYROPHOSPH_2; PS00810 ADP_GLC_PYROPHOSPH_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDEMLGIILAGGQGTRLGKLTKDTAKPAVPFGGRYRIIDFTLSNCANSGVNTVGVITQY
CCCCEEEEEEECCCCCCCCCCCHHCCCCCCCCCCEEEEEEEEEHHHCCCCCCEEEEEEEC
QPLELNAHIGSGASWGFDSLNGGVTVLQPYSSSEGEKFFQGTAHAIYQNIEYIDQQDPKY
CCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
LLVLSGDHIYKMDYDAMLKYHQEKKASLTVGVIHVTNEEAKRFGMMNTDATDRIIEFEEK
EEEEECCEEEEECHHHHHHHHHHCCCEEEEEEEEEECHHHHHCCCCCCCCCHHEEEECCC
PEHPKSDKASMGIYIFNWPTLRDYLVKSYATDKSLEDFGKNVIPSYLANNESVYAYAFKG
CCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHCHHHHCCCCCEEEEEECC
YWRDVGTIKSLWQANMEFLSPHNRLNIGDRYWRIYSKAEVLPPMFLTETSQVNNAMVVDS
HHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHEEEECHHHCCCCEEEECCCCCCCEEEEEE
CYVAGEIDHSILSQRVSVGMGSRVVDSMIMPGATIGKNVVIDHALIGEDAVIGDDAQIIG
EEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCEECCCCEEEE
TTDKIAVVGYHETMGVEQP
CCCCEEEEEEHHHCCCCCC
>Mature Secondary Structure
MQDEMLGIILAGGQGTRLGKLTKDTAKPAVPFGGRYRIIDFTLSNCANSGVNTVGVITQY
CCCCEEEEEEECCCCCCCCCCCHHCCCCCCCCCCEEEEEEEEEHHHCCCCCCEEEEEEEC
QPLELNAHIGSGASWGFDSLNGGVTVLQPYSSSEGEKFFQGTAHAIYQNIEYIDQQDPKY
CCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
LLVLSGDHIYKMDYDAMLKYHQEKKASLTVGVIHVTNEEAKRFGMMNTDATDRIIEFEEK
EEEEECCEEEEECHHHHHHHHHHCCCEEEEEEEEEECHHHHHCCCCCCCCCHHEEEECCC
PEHPKSDKASMGIYIFNWPTLRDYLVKSYATDKSLEDFGKNVIPSYLANNESVYAYAFKG
CCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHCHHHHCCCCCEEEEEECC
YWRDVGTIKSLWQANMEFLSPHNRLNIGDRYWRIYSKAEVLPPMFLTETSQVNNAMVVDS
HHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHEEEECHHHCCCCEEEECCCCCCCEEEEEE
CYVAGEIDHSILSQRVSVGMGSRVVDSMIMPGATIGKNVVIDHALIGEDAVIGDDAQIIG
EEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCEECCCCEEEE
TTDKIAVVGYHETMGVEQP
CCCCEEEEEEHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12566566