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The map label for this gene is czcD [H]

Identifier: 28212042

GI number: 28212042

Start: 2607073

End: 2608257

Strand: Direct

Name: czcD [H]

Synonym: CTC02458

Alternate gene names: 28212042

Gene position: 2607073-2608257 (Clockwise)

Preceding gene: 28212036

Following gene: 28212043

Centisome position: 93.13

GC content: 27.17

Gene sequence:

>1185_bases
ATGATGTCCAAATTCCTTGTTAAAACTTTTGTTAAAAATTATAAAAATATAGATGATACCAAAGTTAGAAATTCCTATGG
TTTCCTTGGAAGTATGGTGGGGATACTTTCTAACACTATTTTATTTATTGTGAAAATAGTAGTTGGGATACTTTCTAATA
GTATTTCTGTTACTGCGGATGCTTTTAATAATTTATCTGATGTTGCATCTTCTGTAATAACCTTAATAGGCTTTAAATTA
TCTTCAAAGCCTGCAGATAAAGAACACCCTTTTGGTCATGGAAGAATAGAATATATATCAGCATTGGTAGTTTCTTTTAT
GGTCATATTAGTAGGACTTGAATTTGTAAAAACATCTTACAACAGAATAGTTAATCCCGTAGATATTAACTTTCAAATAA
TCCCTTTTATTCTTATAGTATTGTCTATTTTTACAAAAGTATGGCTTAGTAGATTTAATAAATATATTGGAGATTCTATT
AATTCTTCTGCACTACAAGCTTCATCTTTTGATGCATTAAGTGATGTAATTACTTCAAGTTGTGTAGCTCTATCTTTAAT
TTTATCAATGTGGATTTCATTTCCTATAGATGGGTATATTGGAATAGTTGTTTCTTTATTTATAATGTATTCTGGTTACA
CTTTAATAAAAGAAACATTAAATCCTCTCTTAGGAGAAGCAGCAGATCCTCAATTAGTAAAAGATATAACAGAAGAAACA
CTAAACTATCCTTATATAGGTGGAGTTCATGATTTAATAGTTCATAATTATGGACCTGGAAGATGTCTTGCATCTATTCA
TGCAGAAGTCCCGGATAATATATCTATTGTTGATATACATGAAATAATAGATAAAGCCGAAAAAGAAATCTCTGAAAAAC
TAAATTTAGAATTAGTTATACACATGGATCCTATAAACACTGATAACAAAGAGATTAATAGCATACAAAAAGAAGTAGAA
GAAATTTTATTAAAATATCCAACTATAAAATCCTTTCATGATTTTAGAGTAGTGGGTTCTGGTGAATTTAAAAATTTAAT
ATTTGATATAGTTATAGATTATTCAGTACCTTTTACTGATGAATTGCATAAAAATTTAAAAGATAATATCTCTAAAGATA
TCAAAAAAATTCACCCTTCATATAATACTATAATAACGATAGATAGAGATTTTACCCATATATAA

Upstream 100 bases:

>100_bases
CCTCCTTACAGTTTTATATTTAAGCACTATCATAATTGATTTCCTTCATTAAATATATCATAATTAATCTATAAAATAAA
TTTTAAGTGAGGTTTTTATA

Downstream 100 bases:

>100_bases
TTTCTTCTTATACTACACATAATACATTTAAAACTTAAGGAGTGTGATTCAATGACTAATGAGAGGCATTTCTTCCCTGG
AAGTAACTCTGCTGATGGTT

Product: cobalt-zinc-cadmium resistance protein czcD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MMSKFLVKTFVKNYKNIDDTKVRNSYGFLGSMVGILSNTILFIVKIVVGILSNSISVTADAFNNLSDVASSVITLIGFKL
SSKPADKEHPFGHGRIEYISALVVSFMVILVGLEFVKTSYNRIVNPVDINFQIIPFILIVLSIFTKVWLSRFNKYIGDSI
NSSALQASSFDALSDVITSSCVALSLILSMWISFPIDGYIGIVVSLFIMYSGYTLIKETLNPLLGEAADPQLVKDITEET
LNYPYIGGVHDLIVHNYGPGRCLASIHAEVPDNISIVDIHEIIDKAEKEISEKLNLELVIHMDPINTDNKEINSIQKEVE
EILLKYPTIKSFHDFRVVGSGEFKNLIFDIVIDYSVPFTDELHKNLKDNISKDIKKIHPSYNTIITIDRDFTHI

Sequences:

>Translated_394_residues
MMSKFLVKTFVKNYKNIDDTKVRNSYGFLGSMVGILSNTILFIVKIVVGILSNSISVTADAFNNLSDVASSVITLIGFKL
SSKPADKEHPFGHGRIEYISALVVSFMVILVGLEFVKTSYNRIVNPVDINFQIIPFILIVLSIFTKVWLSRFNKYIGDSI
NSSALQASSFDALSDVITSSCVALSLILSMWISFPIDGYIGIVVSLFIMYSGYTLIKETLNPLLGEAADPQLVKDITEET
LNYPYIGGVHDLIVHNYGPGRCLASIHAEVPDNISIVDIHEIIDKAEKEISEKLNLELVIHMDPINTDNKEINSIQKEVE
EILLKYPTIKSFHDFRVVGSGEFKNLIFDIVIDYSVPFTDELHKNLKDNISKDIKKIHPSYNTIITIDRDFTHI
>Mature_394_residues
MMSKFLVKTFVKNYKNIDDTKVRNSYGFLGSMVGILSNTILFIVKIVVGILSNSISVTADAFNNLSDVASSVITLIGFKL
SSKPADKEHPFGHGRIEYISALVVSFMVILVGLEFVKTSYNRIVNPVDINFQIIPFILIVLSIFTKVWLSRFNKYIGDSI
NSSALQASSFDALSDVITSSCVALSLILSMWISFPIDGYIGIVVSLFIMYSGYTLIKETLNPLLGEAADPQLVKDITEET
LNYPYIGGVHDLIVHNYGPGRCLASIHAEVPDNISIVDIHEIIDKAEKEISEKLNLELVIHMDPINTDNKEINSIQKEVE
EILLKYPTIKSFHDFRVVGSGEFKNLIFDIVIDYSVPFTDELHKNLKDNISKDIKKIHPSYNTIITIDRDFTHI

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790349, Length=274, Percent_Identity=25.5474452554745, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6325032, Length=237, Percent_Identity=26.1603375527426, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323831, Length=355, Percent_Identity=25.0704225352113, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 44120; Mature: 44120

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSKFLVKTFVKNYKNIDDTKVRNSYGFLGSMVGILSNTILFIVKIVVGILSNSISVTAD
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
AFNNLSDVASSVITLIGFKLSSKPADKEHPFGHGRIEYISALVVSFMVILVGLEFVKTSY
HHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NRIVNPVDINFQIIPFILIVLSIFTKVWLSRFNKYIGDSINSSALQASSFDALSDVITSS
HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
CVALSLILSMWISFPIDGYIGIVVSLFIMYSGYTLIKETLNPLLGEAADPQLVKDITEET
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LNYPYIGGVHDLIVHNYGPGRCLASIHAEVPDNISIVDIHEIIDKAEKEISEKLNLELVI
CCCCCCCCHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCEEEEE
HMDPINTDNKEINSIQKEVEEILLKYPTIKSFHDFRVVGSGEFKNLIFDIVIDYSVPFTD
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCHH
ELHKNLKDNISKDIKKIHPSYNTIITIDRDFTHI
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MMSKFLVKTFVKNYKNIDDTKVRNSYGFLGSMVGILSNTILFIVKIVVGILSNSISVTAD
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
AFNNLSDVASSVITLIGFKLSSKPADKEHPFGHGRIEYISALVVSFMVILVGLEFVKTSY
HHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NRIVNPVDINFQIIPFILIVLSIFTKVWLSRFNKYIGDSINSSALQASSFDALSDVITSS
HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
CVALSLILSMWISFPIDGYIGIVVSLFIMYSGYTLIKETLNPLLGEAADPQLVKDITEET
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LNYPYIGGVHDLIVHNYGPGRCLASIHAEVPDNISIVDIHEIIDKAEKEISEKLNLELVI
CCCCCCCCHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCEEEEE
HMDPINTDNKEINSIQKEVEEILLKYPTIKSFHDFRVVGSGEFKNLIFDIVIDYSVPFTD
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCHH
ELHKNLKDNISKDIKKIHPSYNTIITIDRDFTHI
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA