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The map label for this gene is gltS [H]

Identifier: 28211919

GI number: 28211919

Start: 2459088

End: 2460311

Strand: Direct

Name: gltS [H]

Synonym: CTC02324

Alternate gene names: 28211919

Gene position: 2459088-2460311 (Clockwise)

Preceding gene: 28211910

Following gene: 28211930

Centisome position: 87.85

GC content: 36.27

Gene sequence:

>1224_bases
GTGGTATTATTTATGGAAATTAAATTGGACATGATGCAAACAGCAGCTTTGGCAGTAGTAATATACTACTTTGGAGCCTG
GATTAAAACTAAAGCTCAAATTTTAGAAAAATTCTGTATACCTGCTCCTGTTGTTGGCGGACTTATTTTTGCTTTTGTAA
ACCTTATCTTAAAACAATCTGGGGCTCTTTCCCTAGAACTCGACACTACATTACAAAAACCATTCATGATGGTATTCTTT
ACTTCCATAGGTATGGGTGCTAGTATCAAACTTATCAAAAAAGGTGGAATTCAGGTTCTTATTTTCTGGCTTGTTGCATC
TTTACTATGTGTATTCCAAAATGCTATTGGTATAGGTCTTGCTAAAGTGCTTAATCAAAGCCCATTACTTGGAATGATTT
GTGGTTCAGTAACCATGACAGGTGGACATGGTACAGGCGGTGCCTTTGGACCTTCCTTTGAAAAGGACTACGGTGTGGTT
GGTGCTACTGCTACTGCTATGGCATCAGCAACTTTTGGACTAGTTATGGGTTCATTAATCGGAGGACCTATTGGTAAAAA
ACTTATTGAGTCTAGAAATTTAAAACCTAATGTAGACGCATATGAATCAGCTGATACAGAAGCAGCTATAACTGCTAAAG
AAGAAGCTATAAGCTATGATGAAGTATTTAAAGCCTTAGCTTTAATACTTATTTCCATAGGTATTGGTGCCGTTTTAGAA
AAATTCTTTGTAAGTATTGGAGTTACTCTTCCATCCTATGTTAACTCTATGATTATAGCAGCAATCATACTTAATGTTGG
GGAATCAACTGGTAAATGGCATGTTAATAGCAAATGTATGGACATCCTTGGTAATATAGGACTTAATGTATTTTTATCCA
TGGCTTTAGTTGGATTAAAATTATGGGAACTTGCAGCTGTTGCAGGACCAATGTTAATCATATTAGTAGCTCAAACTATA
TTTATGGCTCTATTTGCTTATTTTGTAACATTCAATCTTCTTGGTAGAGACTTTGATGCAGCTGTACTTGCTGCAGGTAA
CTGTGGATTTGGTATGGGAGCCACTCCTAACGGAATTGCAAATATGACCGCAGTTGTTGAAAGATATGGACCTGCTCCTA
GGGCTTTCTTCGTATTGCCTATAGTTGGTGCATTCCTCATAGACTTCTCCAACTCCATAATAATAGCTGGATTTTTAAAC
TTTGTAACTAAATATTTATTATAA

Upstream 100 bases:

>100_bases
ATTAATATTTCATTTATTAAAATTTTCTCATTGATTTTTATCCCATCTTTATTTATAATGAAGTTGTAATGAAAATCTTT
TCATTCATTATTATAGAAAG

Downstream 100 bases:

>100_bases
AATAGAAATGCTAGCATTTTTGCTAGCATTTCTATTTTATATATTTGTCCCAATAGTTCCTTTATAATCTTTTATTATCC
TTTCCTCTTTATACATATAC

Product: sodium/glutamate symport carrier protein

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MVLFMEIKLDMMQTAALAVVIYYFGAWIKTKAQILEKFCIPAPVVGGLIFAFVNLILKQSGALSLELDTTLQKPFMMVFF
TSIGMGASIKLIKKGGIQVLIFWLVASLLCVFQNAIGIGLAKVLNQSPLLGMICGSVTMTGGHGTGGAFGPSFEKDYGVV
GATATAMASATFGLVMGSLIGGPIGKKLIESRNLKPNVDAYESADTEAAITAKEEAISYDEVFKALALILISIGIGAVLE
KFFVSIGVTLPSYVNSMIIAAIILNVGESTGKWHVNSKCMDILGNIGLNVFLSMALVGLKLWELAAVAGPMLIILVAQTI
FMALFAYFVTFNLLGRDFDAAVLAAGNCGFGMGATPNGIANMTAVVERYGPAPRAFFVLPIVGAFLIDFSNSIIIAGFLN
FVTKYLL

Sequences:

>Translated_407_residues
MVLFMEIKLDMMQTAALAVVIYYFGAWIKTKAQILEKFCIPAPVVGGLIFAFVNLILKQSGALSLELDTTLQKPFMMVFF
TSIGMGASIKLIKKGGIQVLIFWLVASLLCVFQNAIGIGLAKVLNQSPLLGMICGSVTMTGGHGTGGAFGPSFEKDYGVV
GATATAMASATFGLVMGSLIGGPIGKKLIESRNLKPNVDAYESADTEAAITAKEEAISYDEVFKALALILISIGIGAVLE
KFFVSIGVTLPSYVNSMIIAAIILNVGESTGKWHVNSKCMDILGNIGLNVFLSMALVGLKLWELAAVAGPMLIILVAQTI
FMALFAYFVTFNLLGRDFDAAVLAAGNCGFGMGATPNGIANMTAVVERYGPAPRAFFVLPIVGAFLIDFSNSIIIAGFLN
FVTKYLL
>Mature_407_residues
MVLFMEIKLDMMQTAALAVVIYYFGAWIKTKAQILEKFCIPAPVVGGLIFAFVNLILKQSGALSLELDTTLQKPFMMVFF
TSIGMGASIKLIKKGGIQVLIFWLVASLLCVFQNAIGIGLAKVLNQSPLLGMICGSVTMTGGHGTGGAFGPSFEKDYGVV
GATATAMASATFGLVMGSLIGGPIGKKLIESRNLKPNVDAYESADTEAAITAKEEAISYDEVFKALALILISIGIGAVLE
KFFVSIGVTLPSYVNSMIIAAIILNVGESTGKWHVNSKCMDILGNIGLNVFLSMALVGLKLWELAAVAGPMLIILVAQTI
FMALFAYFVTFNLLGRDFDAAVLAAGNCGFGMGATPNGIANMTAVVERYGPAPRAFFVLPIVGAFLIDFSNSIIIAGFLN
FVTKYLL

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=365, Percent_Identity=44.6575342465753, Blast_Score=278, Evalue=6e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 43100; Mature: 43100

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLFMEIKLDMMQTAALAVVIYYFGAWIKTKAQILEKFCIPAPVVGGLIFAFVNLILKQS
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
GALSLELDTTLQKPFMMVFFTSIGMGASIKLIKKGGIQVLIFWLVASLLCVFQNAIGIGL
CCEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AKVLNQSPLLGMICGSVTMTGGHGTGGAFGPSFEKDYGVVGATATAMASATFGLVMGSLI
HHHHCCCCCHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GGPIGKKLIESRNLKPNVDAYESADTEAAITAKEEAISYDEVFKALALILISIGIGAVLE
CCHHHHHHHHHCCCCCCCCCCCCCCCCHHEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
KFFVSIGVTLPSYVNSMIIAAIILNVGESTGKWHVNSKCMDILGNIGLNVFLSMALVGLK
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHH
LWELAAVAGPMLIILVAQTIFMALFAYFVTFNLLGRDFDAAVLAAGNCGFGMGATPNGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHH
NMTAVVERYGPAPRAFFVLPIVGAFLIDFSNSIIIAGFLNFVTKYLL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
>Mature Secondary Structure
MVLFMEIKLDMMQTAALAVVIYYFGAWIKTKAQILEKFCIPAPVVGGLIFAFVNLILKQS
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
GALSLELDTTLQKPFMMVFFTSIGMGASIKLIKKGGIQVLIFWLVASLLCVFQNAIGIGL
CCEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AKVLNQSPLLGMICGSVTMTGGHGTGGAFGPSFEKDYGVVGATATAMASATFGLVMGSLI
HHHHCCCCCHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GGPIGKKLIESRNLKPNVDAYESADTEAAITAKEEAISYDEVFKALALILISIGIGAVLE
CCHHHHHHHHHCCCCCCCCCCCCCCCCHHEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
KFFVSIGVTLPSYVNSMIIAAIILNVGESTGKWHVNSKCMDILGNIGLNVFLSMALVGLK
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHH
LWELAAVAGPMLIILVAQTIFMALFAYFVTFNLLGRDFDAAVLAAGNCGFGMGATPNGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHH
NMTAVVERYGPAPRAFFVLPIVGAFLIDFSNSIIIAGFLNFVTKYLL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]