Click here to switch to the map view.

The map label for this gene is dppF [H]

Identifier: 28211538

GI number: 28211538

Start: 2025541

End: 2026143

Strand: Direct

Name: dppF [H]

Synonym: CTC01904

Alternate gene names: 28211538

Gene position: 2025541-2026143 (Clockwise)

Preceding gene: 28211537

Following gene: 28211543

Centisome position: 72.36

GC content: 35.99

Gene sequence:

>603_bases
ATGCATTTAATTGGTAAAAACCTTGGTTACTATTATCAAGAAGAGCAATGGCTCTTTAAAGATGTTAATCTTTCTGTGTC
ACCTGGAGAAGTATTAGGTTTATCCGGTTATAGTGGATGTGGAAAAACTACTCTAGCCAAAATCTTAGCTGGATATATCC
AACCTCGTAAAGGAATGGTGATGTTGGATCAAAAACCCATAGAACAACGAGTTTTTCGTCCGGTACAATTAATTTATCAG
CATCCAGAAAAAGCTATTAATCCTAAATGGCGAATGCGAGAAGTTTTAGCAGAATCCTACAAACCATCGCAGGATATTCT
TGATGCTTTTGGAATAAAGGATGAATGGATGGATCGTTGGCCTATTGAACTTTCTGGCGGAGAATTACAGCGATTTTGTA
TTGTTCGTGCATTGAATCCCGCTACTAAATATATAATTGCTGATGAAATGACCACTATGTTGGATGCAATTACACAGGCA
AAAATATGGCACAGTCTTCTTTCAATATGTGAAAGTAGAAGAATCGGACTCATTGTAGTAAGTCATGAAAAAAGCTTAAT
CAATAGAATATGTAATCGAGTATACAACGTTGGGCAAAATTAA

Upstream 100 bases:

>100_bases
AAGGCGATCGTCTGAAAACTGAATATGCCAAAAGATTATGGAGAGCTTTGCCACAAAATGATTTTCATTTGGAATTTCAA
ATAAATGGAGGAGGTATATA

Downstream 100 bases:

>100_bases
ACTAATCTAGAAATAAAATCAGTCATGTAGATACAATATTTAAGAACGCTTATTTCTGCATAGAAATAAGCGTTCTTTTT
TCTTATAAAATAGGAAATAT

Product: dipeptide transport ATP-binding protein dppF

Products: Ni2; [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MHLIGKNLGYYYQEEQWLFKDVNLSVSPGEVLGLSGYSGCGKTTLAKILAGYIQPRKGMVMLDQKPIEQRVFRPVQLIYQ
HPEKAINPKWRMREVLAESYKPSQDILDAFGIKDEWMDRWPIELSGGELQRFCIVRALNPATKYIIADEMTTMLDAITQA
KIWHSLLSICESRRIGLIVVSHEKSLINRICNRVYNVGQN

Sequences:

>Translated_200_residues
MHLIGKNLGYYYQEEQWLFKDVNLSVSPGEVLGLSGYSGCGKTTLAKILAGYIQPRKGMVMLDQKPIEQRVFRPVQLIYQ
HPEKAINPKWRMREVLAESYKPSQDILDAFGIKDEWMDRWPIELSGGELQRFCIVRALNPATKYIIADEMTTMLDAITQA
KIWHSLLSICESRRIGLIVVSHEKSLINRICNRVYNVGQN
>Mature_200_residues
MHLIGKNLGYYYQEEQWLFKDVNLSVSPGEVLGLSGYSGCGKTTLAKILAGYIQPRKGMVMLDQKPIEQRVFRPVQLIYQ
HPEKAINPKWRMREVLAESYKPSQDILDAFGIKDEWMDRWPIELSGGELQRFCIVRALNPATKYIIADEMTTMLDAITQA
KIWHSLLSICESRRIGLIVVSHEKSLINRICNRVYNVGQN

Specific function: Part of a transport system that may be involved in oligopeptide uptake. Probably responsible for energy coupling to the transport system. Important for S.aureus growth and survival during the infection process [H]

COG id: COG1124

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9665248, Length=201, Percent_Identity=24.8756218905473, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789891, Length=201, Percent_Identity=32.3383084577114, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787758, Length=185, Percent_Identity=32.972972972973, Blast_Score=106, Evalue=8e-25,
Organism=Escherichia coli, GI1787500, Length=193, Percent_Identity=32.6424870466321, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1789890, Length=200, Percent_Identity=34, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1788506, Length=201, Percent_Identity=28.8557213930348, Blast_Score=97, Evalue=5e-22,
Organism=Escherichia coli, GI145693107, Length=194, Percent_Identity=30.4123711340206, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787547, Length=207, Percent_Identity=26.5700483091787, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789962, Length=192, Percent_Identity=26.5625, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87081791, Length=201, Percent_Identity=29.3532338308458, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787759, Length=204, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI48994883, Length=200, Percent_Identity=29.5, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1789963, Length=217, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786703, Length=210, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786398, Length=201, Percent_Identity=29.8507462686567, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786698, Length=200, Percent_Identity=29, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87081834, Length=208, Percent_Identity=29.3269230769231, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI48994997, Length=209, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1787548, Length=204, Percent_Identity=25.4901960784314, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1786253, Length=197, Percent_Identity=27.9187817258883, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788225, Length=206, Percent_Identity=25.2427184466019, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1787112, Length=196, Percent_Identity=28.0612244897959, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI87081709, Length=184, Percent_Identity=25.5434782608696, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786345, Length=191, Percent_Identity=26.7015706806283, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789032, Length=192, Percent_Identity=26.0416666666667, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787370, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787029, Length=205, Percent_Identity=25.8536585365854, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788165, Length=179, Percent_Identity=26.8156424581006, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1787164, Length=199, Percent_Identity=23.1155778894472, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788540, Length=197, Percent_Identity=27.4111675126904, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789593, Length=220, Percent_Identity=26.3636363636364, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790739, Length=213, Percent_Identity=26.2910798122066, Blast_Score=60, Evalue=8e-11,
Organism=Escherichia coli, GI1789751, Length=181, Percent_Identity=28.1767955801105, Blast_Score=60, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=204, Percent_Identity=25.9803921568627, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17558664, Length=187, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI115533608, Length=206, Percent_Identity=28.1553398058252, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17569143, Length=203, Percent_Identity=28.0788177339901, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24659289, Length=211, Percent_Identity=27.9620853080569, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221500365, Length=199, Percent_Identity=25.6281407035176, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007184, Length=199, Percent_Identity=25.6281407035176, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 22986; Mature: 22986

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLIGKNLGYYYQEEQWLFKDVNLSVSPGEVLGLSGYSGCGKTTLAKILAGYIQPRKGMV
CCCCCCCCCCEECCCCCEEHHCCCEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCEE
MLDQKPIEQRVFRPVQLIYQHPEKAINPKWRMREVLAESYKPSQDILDAFGIKDEWMDRW
EECCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHCCC
PIELSGGELQRFCIVRALNPATKYIIADEMTTMLDAITQAKIWHSLLSICESRRIGLIVV
CEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
SHEKSLINRICNRVYNVGQN
ECCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHLIGKNLGYYYQEEQWLFKDVNLSVSPGEVLGLSGYSGCGKTTLAKILAGYIQPRKGMV
CCCCCCCCCCEECCCCCEEHHCCCEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCEE
MLDQKPIEQRVFRPVQLIYQHPEKAINPKWRMREVLAESYKPSQDILDAFGIKDEWMDRW
EECCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHCCC
PIELSGGELQRFCIVRALNPATKYIIADEMTTMLDAITQAKIWHSLLSICESRRIGLIVV
CEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
SHEKSLINRICNRVYNVGQN
ECCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; ATP; H2O [C]

Specific reaction: Ni2+ [Periplasm] + ATP + H2O = Ni2+ [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA