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The map label for this gene is dppD [H]

Identifier: 28211537

GI number: 28211537

Start: 2024720

End: 2025541

Strand: Direct

Name: dppD [H]

Synonym: CTC01903

Alternate gene names: 28211537

Gene position: 2024720-2025541 (Clockwise)

Preceding gene: 28211536

Following gene: 28211538

Centisome position: 72.33

GC content: 38.93

Gene sequence:

>822_bases
ATGAATACCACACAAAAAGAATTATTACTCCAGGTAAAAAACCTAAAAATTAGTTTTTCTCAATACTTTAAAGGAACACA
GAAACGTATAATTCAACCTATATCGGATTTACATGTAGATATTAATCAAGGAGAAATTGTGGCCGTAGTAGGAGCTAGTG
GTTCAGGGAAAAGCCTCTTGGCACATGCTGTATTAGGAATACTACCTAGCAATGCTATTTGTCAAGGGCAAATACTTTAC
CGTGGAGAATCCCTGACAGAAGAACGAAAAGCACAGTTGCGAGGGCGAGAAATCTCTTTTATCCCTCAATCAGTAAATTA
TTTAGATCCGTTAATGAGGGTTGGAAAACAGGTTCAGATTGGTCTAGAAAAAAGTATAGCAAGGAAATCGCAACAAGAGC
TGTTCCAACAATATGACCTAAAGGAAAGTGACGGTAGCTTATTTCCCTACGAGCTTTCTGGAGGTATGCTCCGTCGAGTT
TTATTTGCCACCAGTGTCCGTAAAGGGGTTCAATTGGTAATTGCTGATGAACCAACACCTGGGATCCATCCCCAAGCCCT
TTCTGAAATTTTAAGGCAAATCAAGCGATTTGCAAAAGAAGGTGCTGGTGTCATGCTAATTACTCACGATATTATGTCAG
CTTTGGAGATTGCAGATCGGGTGGCAGTAATCAAAGATGGTCAAACAATAGAAATTTCTGAAGCATCAGCTTTTGAAGGC
AAAGGCGATCGTCTGAAAACTGAATATGCCAAAAGATTATGGAGAGCTTTGCCACAAAATGATTTTCATTTGGAATTTCA
AATAAATGGAGGAGGTATATAA

Upstream 100 bases:

>100_bases
GTTACTTTTAGTTATAGTAATTAAGAGCTTTGACAATATTGGGGAGCAACTACGTATTTTAATGGAACCTGTTAGTTCCA
ATGAATAAGGAGGAACTATA

Downstream 100 bases:

>100_bases
TGCATTTAATTGGTAAAAACCTTGGTTACTATTATCAAGAAGAGCAATGGCTCTTTAAAGATGTTAATCTTTCTGTGTCA
CCTGGAGAAGTATTAGGTTT

Product: dipeptide transport ATP-binding protein dppD

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: Stage 0 sporulation protein KD [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MNTTQKELLLQVKNLKISFSQYFKGTQKRIIQPISDLHVDINQGEIVAVVGASGSGKSLLAHAVLGILPSNAICQGQILY
RGESLTEERKAQLRGREISFIPQSVNYLDPLMRVGKQVQIGLEKSIARKSQQELFQQYDLKESDGSLFPYELSGGMLRRV
LFATSVRKGVQLVIADEPTPGIHPQALSEILRQIKRFAKEGAGVMLITHDIMSALEIADRVAVIKDGQTIEISEASAFEG
KGDRLKTEYAKRLWRALPQNDFHLEFQINGGGI

Sequences:

>Translated_273_residues
MNTTQKELLLQVKNLKISFSQYFKGTQKRIIQPISDLHVDINQGEIVAVVGASGSGKSLLAHAVLGILPSNAICQGQILY
RGESLTEERKAQLRGREISFIPQSVNYLDPLMRVGKQVQIGLEKSIARKSQQELFQQYDLKESDGSLFPYELSGGMLRRV
LFATSVRKGVQLVIADEPTPGIHPQALSEILRQIKRFAKEGAGVMLITHDIMSALEIADRVAVIKDGQTIEISEASAFEG
KGDRLKTEYAKRLWRALPQNDFHLEFQINGGGI
>Mature_273_residues
MNTTQKELLLQVKNLKISFSQYFKGTQKRIIQPISDLHVDINQGEIVAVVGASGSGKSLLAHAVLGILPSNAICQGQILY
RGESLTEERKAQLRGREISFIPQSVNYLDPLMRVGKQVQIGLEKSIARKSQQELFQQYDLKESDGSLFPYELSGGMLRRV
LFATSVRKGVQLVIADEPTPGIHPQALSEILRQIKRFAKEGAGVMLITHDIMSALEIADRVAVIKDGQTIEISEASAFEG
KGDRLKTEYAKRLWRALPQNDFHLEFQINGGGI

Specific function: Part of the binding protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Required for sporulation and competence [H]

COG id: COG0444

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI150417984, Length=216, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI27262624, Length=195, Percent_Identity=27.1794871794872, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI27262626, Length=195, Percent_Identity=27.1794871794872, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI27436953, Length=195, Percent_Identity=27.1794871794872, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI31657092, Length=219, Percent_Identity=25.1141552511416, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI48994883, Length=244, Percent_Identity=31.5573770491803, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787759, Length=238, Percent_Identity=33.1932773109244, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI145693107, Length=271, Percent_Identity=32.1033210332103, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1789963, Length=267, Percent_Identity=30.3370786516854, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1788506, Length=268, Percent_Identity=29.4776119402985, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787548, Length=275, Percent_Identity=29.4545454545455, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789890, Length=209, Percent_Identity=32.5358851674641, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787105, Length=230, Percent_Identity=32.6086956521739, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789891, Length=227, Percent_Identity=29.5154185022026, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1787500, Length=279, Percent_Identity=24.7311827956989, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786872, Length=213, Percent_Identity=30.9859154929577, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786398, Length=232, Percent_Identity=31.0344827586207, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789593, Length=251, Percent_Identity=26.2948207171315, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787029, Length=230, Percent_Identity=28.2608695652174, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789991, Length=262, Percent_Identity=26.7175572519084, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788225, Length=222, Percent_Identity=28.3783783783784, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87081834, Length=241, Percent_Identity=29.8755186721992, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787089, Length=217, Percent_Identity=28.110599078341, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789032, Length=247, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081791, Length=255, Percent_Identity=27.843137254902, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48995001, Length=207, Percent_Identity=28.5024154589372, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788761, Length=270, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI48994997, Length=210, Percent_Identity=29.0476190476191, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789672, Length=238, Percent_Identity=25.2100840336134, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789962, Length=242, Percent_Identity=26.4462809917355, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788897, Length=206, Percent_Identity=24.2718446601942, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787758, Length=241, Percent_Identity=25.7261410788382, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787792, Length=241, Percent_Identity=24.896265560166, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082268, Length=211, Percent_Identity=24.1706161137441, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786703, Length=236, Percent_Identity=28.3898305084746, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788450, Length=225, Percent_Identity=28.4444444444444, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790190, Length=244, Percent_Identity=25, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787370, Length=200, Percent_Identity=26.5, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1786319, Length=236, Percent_Identity=25.8474576271186, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788472, Length=208, Percent_Identity=22.1153846153846, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789873, Length=208, Percent_Identity=28.3653846153846, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787112, Length=206, Percent_Identity=27.6699029126214, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790467, Length=202, Percent_Identity=28.2178217821782, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI87081709, Length=206, Percent_Identity=27.6699029126214, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1788210, Length=219, Percent_Identity=23.7442922374429, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1790525, Length=238, Percent_Identity=22.6890756302521, Blast_Score=61, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24666092, Length=204, Percent_Identity=30.8823529411765, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 30298; Mature: 30298

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTQKELLLQVKNLKISFSQYFKGTQKRIIQPISDLHVDINQGEIVAVVGASGSGKSLL
CCCHHHHHHHHHHHCEEEHHHHHCHHHHHHHCCHHHCEEECCCCCEEEEEECCCCCHHHH
AHAVLGILPSNAICQGQILYRGESLTEERKAQLRGREISFIPQSVNYLDPLMRVGKQVQI
HHHHHHHCCCCCEECCEEEECCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEE
GLEKSIARKSQQELFQQYDLKESDGSLFPYELSGGMLRRVLFATSVRKGVQLVIADEPTP
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCC
GIHPQALSEILRQIKRFAKEGAGVMLITHDIMSALEIADRVAVIKDGQTIEISEASAFEG
CCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHEEEECCCEEEECCCCCCCC
KGDRLKTEYAKRLWRALPQNDFHLEFQINGGGI
CCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MNTTQKELLLQVKNLKISFSQYFKGTQKRIIQPISDLHVDINQGEIVAVVGASGSGKSLL
CCCHHHHHHHHHHHCEEEHHHHHCHHHHHHHCCHHHCEEECCCCCEEEEEECCCCCHHHH
AHAVLGILPSNAICQGQILYRGESLTEERKAQLRGREISFIPQSVNYLDPLMRVGKQVQI
HHHHHHHCCCCCEECCEEEECCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEE
GLEKSIARKSQQELFQQYDLKESDGSLFPYELSGGMLRRVLFATSVRKGVQLVIADEPTP
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCC
GIHPQALSEILRQIKRFAKEGAGVMLITHDIMSALEIADRVAVIKDGQTIEISEASAFEG
CCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHEEEECCCEEEECCCCCCCC
KGDRLKTEYAKRLWRALPQNDFHLEFQINGGGI
CCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1901616; 1899858; 9384377 [H]