Click here to switch to the map view.

The map label for this gene is rocF [H]

Identifier: 28211413

GI number: 28211413

Start: 1874307

End: 1875203

Strand: Direct

Name: rocF [H]

Synonym: CTC01763

Alternate gene names: 28211413

Gene position: 1874307-1875203 (Clockwise)

Preceding gene: 28211407

Following gene: 28211421

Centisome position: 66.96

GC content: 31.22

Gene sequence:

>897_bases
ATGAATATTAATTTAATTGGTGTTCCATTATTCTATGGTTCCGATATTGAAGGAGTAGAATTTGGTCCTAAAAAATTAAG
AGAAAAAAATATAGTAGAGGTTTTAAGTAAATATCATAGGGTATACGATTTTGGTGATTTATATGTTCCGGAGGAAAACT
CACTAAATAAATATTCCTATCATCCAAAAATGAAATATTTAAAACCAATAATTCAGGTAAATACCAATTTAGCTCAGGAG
GTATATGCTTCTCTTAGTTCTAAAAGTTTCCCTCTTATATTAGGCGGAGATCATTCATTAGCCCTTGGAAGTATTTCTGG
TGTTAGTAAATACTATAAAAATTTTGCAGTAATATGGGTAGATGCTCATGGAGATATAAACTCTTACTTAACTACTCATA
CTGGAAATGTGCATGGTATGCCTCTTGCAGCTGCCATGGGTGTTGGATATAATGACCTAACAAATCTTTATTTCCACGGT
ACCAAAGTTAAACCAGAAAATGTATTTATAATAGGTGCTAGAGATTTAGATGAGGGTGAATGTGAACTAATAGAAGAGAA
AAATTTAAATGTATATTCCACTGAGGACATTAAATATAAAGGTATCTCCTATGTACTGGAAGATATTCTTTCTAAATTGG
ATGCTCAGGGGATTGATGCTATACATTTAAGTTTTGATATAGATTGTATAGATCCAGACTTTGTTCCTGGTACAGGTACA
CCTGTAAAAGATGGACTTTCTACAGGTGAGGCTAAAACCTTATTAAAATCCTTATGTGAAAGTAGATTAATTAAATCTAT
GGATTTTGTTGAATTAAATCCTAGATTGGATAAAGATGATAGTACATCTAATCTATGTATTGAACTGCTAGACTGGTGTT
TTAAGTATATCAAATAA

Upstream 100 bases:

>100_bases
ACCTTATATATTTTCTTAATTTGTTATATAATCTTTTATCGTACTAAAAAAATAATTATATTAGAAAAACCTTGTTAATA
TGGCGAGAGGGGGTACTTAA

Downstream 100 bases:

>100_bases
AAATTTTGTAAAGGAAAACTTTTATTTAATGAATAACTAACAATGAATAATTATGGATAACTTTTCTCCATAATTGTTCA
TTGTTAATTAAATACTAATA

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNINLIGVPLFYGSDIEGVEFGPKKLREKNIVEVLSKYHRVYDFGDLYVPEENSLNKYSYHPKMKYLKPIIQVNTNLAQE
VYASLSSKSFPLILGGDHSLALGSISGVSKYYKNFAVIWVDAHGDINSYLTTHTGNVHGMPLAAAMGVGYNDLTNLYFHG
TKVKPENVFIIGARDLDEGECELIEEKNLNVYSTEDIKYKGISYVLEDILSKLDAQGIDAIHLSFDIDCIDPDFVPGTGT
PVKDGLSTGEAKTLLKSLCESRLIKSMDFVELNPRLDKDDSTSNLCIELLDWCFKYIK

Sequences:

>Translated_298_residues
MNINLIGVPLFYGSDIEGVEFGPKKLREKNIVEVLSKYHRVYDFGDLYVPEENSLNKYSYHPKMKYLKPIIQVNTNLAQE
VYASLSSKSFPLILGGDHSLALGSISGVSKYYKNFAVIWVDAHGDINSYLTTHTGNVHGMPLAAAMGVGYNDLTNLYFHG
TKVKPENVFIIGARDLDEGECELIEEKNLNVYSTEDIKYKGISYVLEDILSKLDAQGIDAIHLSFDIDCIDPDFVPGTGT
PVKDGLSTGEAKTLLKSLCESRLIKSMDFVELNPRLDKDDSTSNLCIELLDWCFKYIK
>Mature_298_residues
MNINLIGVPLFYGSDIEGVEFGPKKLREKNIVEVLSKYHRVYDFGDLYVPEENSLNKYSYHPKMKYLKPIIQVNTNLAQE
VYASLSSKSFPLILGGDHSLALGSISGVSKYYKNFAVIWVDAHGDINSYLTTHTGNVHGMPLAAAMGVGYNDLTNLYFHG
TKVKPENVFIIGARDLDEGECELIEEKNLNVYSTEDIKYKGISYVLEDILSKLDAQGIDAIHLSFDIDCIDPDFVPGTGT
PVKDGLSTGEAKTLLKSLCESRLIKSMDFVELNPRLDKDDSTSNLCIELLDWCFKYIK

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=308, Percent_Identity=33.7662337662338, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI10947139, Length=301, Percent_Identity=34.5514950166113, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI37537722, Length=299, Percent_Identity=25.752508361204, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1789306, Length=201, Percent_Identity=27.8606965174129, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71996843, Length=233, Percent_Identity=31.7596566523605, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6325146, Length=209, Percent_Identity=35.4066985645933, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24638886, Length=312, Percent_Identity=29.8076923076923, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 33313; Mature: 33313

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINLIGVPLFYGSDIEGVEFGPKKLREKNIVEVLSKYHRVYDFGDLYVPEENSLNKYSY
CCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCEEC
HPKMKYLKPIIQVNTNLAQEVYASLSSKSFPLILGGDHSLALGSISGVSKYYKNFAVIWV
CCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCEEECCHHHHHHHHCCEEEEEE
DAHGDINSYLTTHTGNVHGMPLAAAMGVGYNDLTNLYFHGTKVKPENVFIIGARDLDEGE
ECCCCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHEEEECCEECCCCEEEEECCCCCCCC
CELIEEKNLNVYSTEDIKYKGISYVLEDILSKLDAQGIDAIHLSFDIDCIDPDFVPGTGT
CEEEECCCCCEEECCCCEECHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCC
PVKDGLSTGEAKTLLKSLCESRLIKSMDFVELNPRLDKDDSTSNLCIELLDWCFKYIK
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNINLIGVPLFYGSDIEGVEFGPKKLREKNIVEVLSKYHRVYDFGDLYVPEENSLNKYSY
CCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCEEC
HPKMKYLKPIIQVNTNLAQEVYASLSSKSFPLILGGDHSLALGSISGVSKYYKNFAVIWV
CCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCEEECCHHHHHHHHCCEEEEEE
DAHGDINSYLTTHTGNVHGMPLAAAMGVGYNDLTNLYFHGTKVKPENVFIIGARDLDEGE
ECCCCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHEEEECCEECCCCEEEEECCCCCCCC
CELIEEKNLNVYSTEDIKYKGISYVLEDILSKLDAQGIDAIHLSFDIDCIDPDFVPGTGT
CEEEECCCCCEEECCCCEECHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCC
PVKDGLSTGEAKTLLKSLCESRLIKSMDFVELNPRLDKDDSTSNLCIELLDWCFKYIK
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]