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The map label for this gene is hbpA [H]

Identifier: 28211078

GI number: 28211078

Start: 1512061

End: 1513647

Strand: Direct

Name: hbpA [H]

Synonym: CTC01400

Alternate gene names: 28211078

Gene position: 1512061-1513647 (Clockwise)

Preceding gene: 28211072

Following gene: 28211079

Centisome position: 54.02

GC content: 28.92

Gene sequence:

>1587_bases
ATGTTAAAGCGATCATTTAATAAAAAAAATATATTTAATAAATTATTAGCACTTGTAATGGTATCATCTATTGCCTTATC
AGGTTGTGGAACTAAATCTGAAAAAGATACTACAAAAACTGATAGTAACAAAGAAATAGTACTGGCATCTCCTAGAGATG
TAGCCCCAGGAAAAGAAAATGTACATTTTGCTAATGTTCTATCCTATGTTTGGGAGCCACTTGTTTCTATGAATAAAAAA
GGTGAGCCCACGCCTAAACTAGCTAAGTCCTGGGAAATGTCAAAGGATGCTAAAGAATGGACTTTTAAACTTCAAGAAGG
AGTAACTTTCCATAATGGTGAAAAATTCAATGCAGATATAGTAGTTGCTAACTTTGATAGGTATAAAAAGCTTAAGAATG
GTAAATCTAATTTCTATACTTTTAAAGTGGACAAGATATATCCAGGGTTAATAGATTGTGTAAAAACAGATGATTACACA
GTTAAATTAAACTTTAAAAAACCTATACCTACACTAGCTTACAATATGGTTAACTTTGGAAGCCCTATATTCCATCCAAA
TGACTTTGGAAAAGATGGAAACTTTATAGTCGATAAGCCTAATGCAACAGGTCCTTTTAAACTAATAGAATCTAAAAAAA
ATTCCTATTGTTTATTAGAAGCTTTTGATAATTATTGGGGTGAAAAAGCAAAATCTAAAAAGATAAGAATAAAAACAATT
CCTGAAGGACAAACAAGATACTCTGCTCTAAAAGCTGGAGAAGTTATGGGTGTTTTAGACTTAGGAGCAATAACTCCAAA
TTTAGCAGAGGAATTATTAAAGGATTCTAAATTTGAAAGTTCTATAGAAAAGTCCACTATTAATCATTTTCTTTCTCTTA
ATGGAACTAAATTTCCATTTAATGACCCTAAAATGAAAGAGGCTGTAAGTCTAGCTATAGACAGAAATTTAATAGTTGAT
AAATTCTATAAAGGATTTGGTAATCCTACACAAAATCTTTTAAACCATGTATCACCATTTTATAAGGAAATGAAACCTGA
ATATAATTTAGAAAAAGCAAAAAAATTAGCTTCAGAAGTATTAAAAGGTAAAAATACAAATGTTACTATGATTATTCCTT
CTGAATTTACTAAGAAATATCCTTATAAAGAAGAAGCTCAATACATACAATCTGTACTAAAAGAATTAGGACTAAATGTA
AATATAAACATATATGACTTTGCTACTTTCAATCAAATAAGAAACAAAGGAGACTTCAACTTACAAATGCATATTCAAGG
TCTACCAAATATGGAACCATACACTATGTTTGATAACTACATGAGAAGTAATGGTTCTACAAATAAAAATTATCATTTTG
GATATAAGAATGATAAAGTTGATAATCTTATGAATAAATTAGATGAAACTTTGGATATTGAAAAAAGAGCTGCTATATAT
GACGAACTTCAAAGTATATCAGCTAAAGATCCTTCTACAATACCTCTATTTAGTGAAATGAATTTAATTGTATCTAATAA
AGAAGTTACTGGACACAATGCATTTATATATGGAACCACTCTTCCAGAACTTCAATGGAGTAAATAA

Upstream 100 bases:

>100_bases
TCTATTTTTATTGATAAGTATAATGTTTATTAATCAGTAGAGCTATCTTCTCTTTATGGAGAAGATTTTTTTATTTTAAA
AATAAACTTGGAGGTTTTCT

Downstream 100 bases:

>100_bases
ATGAAAGAATCCTTAAAGTATTTATTTAAAAAATTAATTCATGCAATTCCTGTACTTATAGGTGTTTCACTTATATCCTT
TATGTTAGGAATATTAGCAC

Product: periplasmic dipeptide transport protein precursor

Products: Ni2; [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MLKRSFNKKNIFNKLLALVMVSSIALSGCGTKSEKDTTKTDSNKEIVLASPRDVAPGKENVHFANVLSYVWEPLVSMNKK
GEPTPKLAKSWEMSKDAKEWTFKLQEGVTFHNGEKFNADIVVANFDRYKKLKNGKSNFYTFKVDKIYPGLIDCVKTDDYT
VKLNFKKPIPTLAYNMVNFGSPIFHPNDFGKDGNFIVDKPNATGPFKLIESKKNSYCLLEAFDNYWGEKAKSKKIRIKTI
PEGQTRYSALKAGEVMGVLDLGAITPNLAEELLKDSKFESSIEKSTINHFLSLNGTKFPFNDPKMKEAVSLAIDRNLIVD
KFYKGFGNPTQNLLNHVSPFYKEMKPEYNLEKAKKLASEVLKGKNTNVTMIIPSEFTKKYPYKEEAQYIQSVLKELGLNV
NINIYDFATFNQIRNKGDFNLQMHIQGLPNMEPYTMFDNYMRSNGSTNKNYHFGYKNDKVDNLMNKLDETLDIEKRAAIY
DELQSISAKDPSTIPLFSEMNLIVSNKEVTGHNAFIYGTTLPELQWSK

Sequences:

>Translated_528_residues
MLKRSFNKKNIFNKLLALVMVSSIALSGCGTKSEKDTTKTDSNKEIVLASPRDVAPGKENVHFANVLSYVWEPLVSMNKK
GEPTPKLAKSWEMSKDAKEWTFKLQEGVTFHNGEKFNADIVVANFDRYKKLKNGKSNFYTFKVDKIYPGLIDCVKTDDYT
VKLNFKKPIPTLAYNMVNFGSPIFHPNDFGKDGNFIVDKPNATGPFKLIESKKNSYCLLEAFDNYWGEKAKSKKIRIKTI
PEGQTRYSALKAGEVMGVLDLGAITPNLAEELLKDSKFESSIEKSTINHFLSLNGTKFPFNDPKMKEAVSLAIDRNLIVD
KFYKGFGNPTQNLLNHVSPFYKEMKPEYNLEKAKKLASEVLKGKNTNVTMIIPSEFTKKYPYKEEAQYIQSVLKELGLNV
NINIYDFATFNQIRNKGDFNLQMHIQGLPNMEPYTMFDNYMRSNGSTNKNYHFGYKNDKVDNLMNKLDETLDIEKRAAIY
DELQSISAKDPSTIPLFSEMNLIVSNKEVTGHNAFIYGTTLPELQWSK
>Mature_528_residues
MLKRSFNKKNIFNKLLALVMVSSIALSGCGTKSEKDTTKTDSNKEIVLASPRDVAPGKENVHFANVLSYVWEPLVSMNKK
GEPTPKLAKSWEMSKDAKEWTFKLQEGVTFHNGEKFNADIVVANFDRYKKLKNGKSNFYTFKVDKIYPGLIDCVKTDDYT
VKLNFKKPIPTLAYNMVNFGSPIFHPNDFGKDGNFIVDKPNATGPFKLIESKKNSYCLLEAFDNYWGEKAKSKKIRIKTI
PEGQTRYSALKAGEVMGVLDLGAITPNLAEELLKDSKFESSIEKSTINHFLSLNGTKFPFNDPKMKEAVSLAIDRNLIVD
KFYKGFGNPTQNLLNHVSPFYKEMKPEYNLEKAKKLASEVLKGKNTNVTMIIPSEFTKKYPYKEEAQYIQSVLKELGLNV
NINIYDFATFNQIRNKGDFNLQMHIQGLPNMEPYTMFDNYMRSNGSTNKNYHFGYKNDKVDNLMNKLDETLDIEKRAAIY
DELQSISAKDPSTIPLFSEMNLIVSNKEVTGHNAFIYGTTLPELQWSK

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789887, Length=521, Percent_Identity=24.1842610364683, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787762, Length=446, Percent_Identity=24.6636771300448, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789966, Length=452, Percent_Identity=26.3274336283186, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787052, Length=438, Percent_Identity=23.972602739726, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1787495, Length=543, Percent_Identity=23.572744014733, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787551, Length=453, Percent_Identity=22.7373068432671, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87081878, Length=518, Percent_Identity=23.5521235521236, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60109; Mature: 60109

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRSFNKKNIFNKLLALVMVSSIALSGCGTKSEKDTTKTDSNKEIVLASPRDVAPGKEN
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
VHFANVLSYVWEPLVSMNKKGEPTPKLAKSWEMSKDAKEWTFKLQEGVTFHNGEKFNADI
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHEEHHCCCEEECCCEECCEE
VVANFDRYKKLKNGKSNFYTFKVDKIYPGLIDCVKTDDYTVKLNFKKPIPTLAYNMVNFG
EEECCHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCCCEEEEEEECCCCHHHHHHHHHCC
SPIFHPNDFGKDGNFIVDKPNATGPFKLIESKKNSYCLLEAFDNYWGEKAKSKKIRIKTI
CCCCCCCCCCCCCCEEEECCCCCCCHHHHCCCCCCEEEEEEHHHHHCCCCCCCEEEEEEC
PEGQTRYSALKAGEVMGVLDLGAITPNLAEELLKDSKFESSIEKSTINHFLSLNGTKFPF
CCCCHHHHHHHHCCEEEEHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
NDPKMKEAVSLAIDRNLIVDKFYKGFGNPTQNLLNHVSPFYKEMKPEYNLEKAKKLASEV
CCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LKGKNTNVTMIIPSEFTKKYPYKEEAQYIQSVLKELGLNVNINIYDFATFNQIRNKGDFN
HCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHCCCCCCE
LQMHIQGLPNMEPYTMFDNYMRSNGSTNKNYHFGYKNDKVDNLMNKLDETLDIEKRAAIY
EEEEECCCCCCCCHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHCHHHHHHHH
DELQSISAKDPSTIPLFSEMNLIVSNKEVTGHNAFIYGTTLPELQWSK
HHHHHCCCCCCCCCCCHHCCEEEEECCEECCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MLKRSFNKKNIFNKLLALVMVSSIALSGCGTKSEKDTTKTDSNKEIVLASPRDVAPGKEN
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
VHFANVLSYVWEPLVSMNKKGEPTPKLAKSWEMSKDAKEWTFKLQEGVTFHNGEKFNADI
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHEEHHCCCEEECCCEECCEE
VVANFDRYKKLKNGKSNFYTFKVDKIYPGLIDCVKTDDYTVKLNFKKPIPTLAYNMVNFG
EEECCHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCCCEEEEEEECCCCHHHHHHHHHCC
SPIFHPNDFGKDGNFIVDKPNATGPFKLIESKKNSYCLLEAFDNYWGEKAKSKKIRIKTI
CCCCCCCCCCCCCCEEEECCCCCCCHHHHCCCCCCEEEEEEHHHHHCCCCCCCEEEEEEC
PEGQTRYSALKAGEVMGVLDLGAITPNLAEELLKDSKFESSIEKSTINHFLSLNGTKFPF
CCCCHHHHHHHHCCEEEEHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
NDPKMKEAVSLAIDRNLIVDKFYKGFGNPTQNLLNHVSPFYKEMKPEYNLEKAKKLASEV
CCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LKGKNTNVTMIIPSEFTKKYPYKEEAQYIQSVLKELGLNVNINIYDFATFNQIRNKGDFN
HCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHCCCCCCE
LQMHIQGLPNMEPYTMFDNYMRSNGSTNKNYHFGYKNDKVDNLMNKLDETLDIEKRAAIY
EEEEECCCCCCCCHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHCHHHHHHHH
DELQSISAKDPSTIPLFSEMNLIVSNKEVTGHNAFIYGTTLPELQWSK
HHHHHCCCCCCCCCCCHHCCEEEEECCEECCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; ATP; H2O [C]

Specific reaction: Ni2+ [Periplasm] + ATP + H2O = Ni2+ [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]