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The map label for this gene is yfbQ [C]

Identifier: 28210979

GI number: 28210979

Start: 1389517

End: 1390710

Strand: Direct

Name: yfbQ [C]

Synonym: CTC01294

Alternate gene names: 28210979

Gene position: 1389517-1390710 (Clockwise)

Preceding gene: 28210978

Following gene: 28210980

Centisome position: 49.64

GC content: 30.32

Gene sequence:

>1194_bases
ATGTTATCTAAAAAAGGAAAGGAAATATCACCTTCTGTTACATTAGCAATAACTGCAAAAGCTAATGAAATGAAGAAGGA
TGGAATAGATGTAGTAGGTTTTGGGGCAGGGGAACCGGATTTTAATACACCTGAAAATATCCAAAATGCTGCAATTAAAG
CAATGAGAGAAGGATATACAAAGTACACACCAGTTTCTGGCGTAGTTGAATTAAAAGATGCTATAGTAAATAAATTCAAA
AAGGAAAATAATTTAATATATAAATCATCACAGATAATAGTATCCACTGGAGCAAAGCAATGTATAGCTAATTTGTTTAT
GGCTATTTTAAATCCAGGAGATGAGGTTTTAATATCTGCACCATATTGGGTTAGTTATCCAGAACTCGTTAAATTAGCAG
ATGGTGTGCCTGTATTTGTAGATTGTAAAAAAGAAAATGATTATAAATACTCTATAGATGAATTAGAAAAGAGGGTTTCT
AGTAAAACAAAGGCTATAATTATTAGTAGTCCGAACAATCCAACAGGAAGTATTTATTATGAAGAAGAGCTTAGAGATAT
AGCTGAATTTTGTAAAAAACATAATTTAATAATTTTATCCGATGAAATATATGAAAAACTTATTTATGGACATAATAAAC
ATATAAGTATAGCTAGCCTAAATGAAGATACTTATAATAGAACTGTTGTAATAAATGGAGTATCTAAGACTTATGCTATG
ACTGGTTGGAGAATAGGATATGCGGCAGGGCCAGGAAATGTAATTAAATTAATGAATAATATACAGAGTCATATGACTTC
AAATCCAAATTCAATCGCTCAATATGCTGCCCTAGAAGCTTTAACAGGAGAGCAGGAGTCTATAAATAGTATGGTGAGTG
AATTTGAAAAGAGAAGAAATTATATGGTGGAAAGAATAAATTCAATAAATGGAATAGAGTGTATAGAGCCTAAAGGAGCC
TTTTATATGTTTGCTGATATAAATAAAGTAATAGGTAAGAAAATCAATGGAGAAGAAATAAAAAACTCTGTGGATTTTTG
TGAAAAATTATTAGAATTATATAAAGTAGCTGTTGTTCCAGGAGCGGCTTTTGGTTTAGAAAATCACATAAGGCTTTCCT
ATGCTATATCTATGGAAAATATAGAAAAAGGATTGGACAGAATATCAAATTGTGTTAGCGAATTACAAAGTTAA

Upstream 100 bases:

>100_bases
TGAAAAAATCAAAAATAAAAATTGCATTTTTCACTTTTATTATGTATTATATTACTATGGCTTAAATTTATATGATATAC
AAAATAGGGGGTGTTTTTAG

Downstream 100 bases:

>100_bases
ATTCTTATATGTTTAAAACGCTTAAATTTAATGTTATAATAAATTTGGTTTATTAATTATTAATACAGAGGTGATACAAA
TGATTAAAAAGGAAGTTGTA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MLSKKGKEISPSVTLAITAKANEMKKDGIDVVGFGAGEPDFNTPENIQNAAIKAMREGYTKYTPVSGVVELKDAIVNKFK
KENNLIYKSSQIIVSTGAKQCIANLFMAILNPGDEVLISAPYWVSYPELVKLADGVPVFVDCKKENDYKYSIDELEKRVS
SKTKAIIISSPNNPTGSIYYEEELRDIAEFCKKHNLIILSDEIYEKLIYGHNKHISIASLNEDTYNRTVVINGVSKTYAM
TGWRIGYAAGPGNVIKLMNNIQSHMTSNPNSIAQYAALEALTGEQESINSMVSEFEKRRNYMVERINSINGIECIEPKGA
FYMFADINKVIGKKINGEEIKNSVDFCEKLLELYKVAVVPGAAFGLENHIRLSYAISMENIEKGLDRISNCVSELQS

Sequences:

>Translated_397_residues
MLSKKGKEISPSVTLAITAKANEMKKDGIDVVGFGAGEPDFNTPENIQNAAIKAMREGYTKYTPVSGVVELKDAIVNKFK
KENNLIYKSSQIIVSTGAKQCIANLFMAILNPGDEVLISAPYWVSYPELVKLADGVPVFVDCKKENDYKYSIDELEKRVS
SKTKAIIISSPNNPTGSIYYEEELRDIAEFCKKHNLIILSDEIYEKLIYGHNKHISIASLNEDTYNRTVVINGVSKTYAM
TGWRIGYAAGPGNVIKLMNNIQSHMTSNPNSIAQYAALEALTGEQESINSMVSEFEKRRNYMVERINSINGIECIEPKGA
FYMFADINKVIGKKINGEEIKNSVDFCEKLLELYKVAVVPGAAFGLENHIRLSYAISMENIEKGLDRISNCVSELQS
>Mature_397_residues
MLSKKGKEISPSVTLAITAKANEMKKDGIDVVGFGAGEPDFNTPENIQNAAIKAMREGYTKYTPVSGVVELKDAIVNKFK
KENNLIYKSSQIIVSTGAKQCIANLFMAILNPGDEVLISAPYWVSYPELVKLADGVPVFVDCKKENDYKYSIDELEKRVS
SKTKAIIISSPNNPTGSIYYEEELRDIAEFCKKHNLIILSDEIYEKLIYGHNKHISIASLNEDTYNRTVVINGVSKTYAM
TGWRIGYAAGPGNVIKLMNNIQSHMTSNPNSIAQYAALEALTGEQESINSMVSEFEKRRNYMVERINSINGIECIEPKGA
FYMFADINKVIGKKINGEEIKNSVDFCEKLLELYKVAVVPGAAFGLENHIRLSYAISMENIEKGLDRISNCVSELQS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=356, Percent_Identity=29.7752808988764, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI56713256, Length=356, Percent_Identity=29.7752808988764, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI95147551, Length=319, Percent_Identity=28.5266457680251, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI169881279, Length=319, Percent_Identity=28.5266457680251, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI169881281, Length=316, Percent_Identity=26.5822784810127, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4507369, Length=378, Percent_Identity=22.7513227513227, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI215599424, Length=351, Percent_Identity=21.6524216524217, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI19263340, Length=351, Percent_Identity=21.6524216524217, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI187936925, Length=361, Percent_Identity=21.0526315789474, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI14211921, Length=361, Percent_Identity=21.0526315789474, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI149944424, Length=172, Percent_Identity=26.7441860465116, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1788627, Length=393, Percent_Identity=31.0432569974555, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786816, Length=366, Percent_Identity=23.7704918032787, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=26.5151515151515, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787909, Length=384, Percent_Identity=19.7916666666667, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788332, Length=237, Percent_Identity=24.0506329113924, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=384, Percent_Identity=27.34375, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71994472, Length=384, Percent_Identity=27.34375, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17567663, Length=371, Percent_Identity=25.0673854447439, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17567369, Length=360, Percent_Identity=26.6666666666667, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI71981209, Length=366, Percent_Identity=22.4043715846995, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=323, Percent_Identity=28.1733746130031, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6323118, Length=371, Percent_Identity=23.7196765498652, Blast_Score=83, Evalue=9e-17,
Organism=Drosophila melanogaster, GI28573069, Length=422, Percent_Identity=28.6729857819905, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24646114, Length=422, Percent_Identity=28.6729857819905, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28573067, Length=422, Percent_Identity=28.6729857819905, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28573065, Length=422, Percent_Identity=28.6729857819905, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI18859735, Length=309, Percent_Identity=23.3009708737864, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45551451, Length=371, Percent_Identity=22.1024258760108, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641770, Length=371, Percent_Identity=22.1024258760108, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641760, Length=371, Percent_Identity=22.1024258760108, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641768, Length=371, Percent_Identity=22.1024258760108, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641766, Length=371, Percent_Identity=22.1024258760108, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641764, Length=371, Percent_Identity=22.1024258760108, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44135; Mature: 44135

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKKGKEISPSVTLAITAKANEMKKDGIDVVGFGAGEPDFNTPENIQNAAIKAMREGYT
CCCCCCCCCCCCEEEEEEECCHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCC
KYTPVSGVVELKDAIVNKFKKENNLIYKSSQIIVSTGAKQCIANLFMAILNPGDEVLISA
CCCCCCHHHHHHHHHHHHHHHCCCEEEECCEEEEECCHHHHHHHHHHHHHCCCCCEEEEC
PYWVSYPELVKLADGVPVFVDCKKENDYKYSIDELEKRVSSKTKAIIISSPNNPTGSIYY
CCCCCCHHHHHHHCCCEEEEEECCCCCCEECHHHHHHHHCCCCCEEEEECCCCCCCCEEE
EEELRDIAEFCKKHNLIILSDEIYEKLIYGHNKHISIASLNEDTYNRTVVINGVSKTYAM
HHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCHHHEE
TGWRIGYAAGPGNVIKLMNNIQSHMTSNPNSIAQYAALEALTGEQESINSMVSEFEKRRN
CCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YMVERINSINGIECIEPKGAFYMFADINKVIGKKINGEEIKNSVDFCEKLLELYKVAVVP
HHHHHHCCCCCEEEECCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GAAFGLENHIRLSYAISMENIEKGLDRISNCVSELQS
CHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSKKGKEISPSVTLAITAKANEMKKDGIDVVGFGAGEPDFNTPENIQNAAIKAMREGYT
CCCCCCCCCCCCEEEEEEECCHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCC
KYTPVSGVVELKDAIVNKFKKENNLIYKSSQIIVSTGAKQCIANLFMAILNPGDEVLISA
CCCCCCHHHHHHHHHHHHHHHCCCEEEECCEEEEECCHHHHHHHHHHHHHCCCCCEEEEC
PYWVSYPELVKLADGVPVFVDCKKENDYKYSIDELEKRVSSKTKAIIISSPNNPTGSIYY
CCCCCCHHHHHHHCCCEEEEEECCCCCCEECHHHHHHHHCCCCCEEEEECCCCCCCCEEE
EEELRDIAEFCKKHNLIILSDEIYEKLIYGHNKHISIASLNEDTYNRTVVINGVSKTYAM
HHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCHHHEE
TGWRIGYAAGPGNVIKLMNNIQSHMTSNPNSIAQYAALEALTGEQESINSMVSEFEKRRN
CCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YMVERINSINGIECIEPKGAFYMFADINKVIGKKINGEEIKNSVDFCEKLLELYKVAVVP
HHHHHHCCCCCEEEECCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GAAFGLENHIRLSYAISMENIEKGLDRISNCVSELQS
CHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1990006; 2155199 [H]