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The map label for this gene is pgsA [H]

Identifier: 28210973

GI number: 28210973

Start: 1382604

End: 1383176

Strand: Direct

Name: pgsA [H]

Synonym: CTC01288

Alternate gene names: 28210973

Gene position: 1382604-1383176 (Clockwise)

Preceding gene: 28210972

Following gene: 28210974

Centisome position: 49.39

GC content: 28.97

Gene sequence:

>573_bases
TTGTATGTGATGAATCTTGCAAATAAATTAACTATAATCAGAATATTTTTAGTACCTGTTTTTTTGATTTTTATAGCCAT
TAATGACATTCCATATGGAAAAACTATAGCTACAGCCATATTTATAATAGCAGCTCTTACAGATAAGTTAGATGGCTATA
TAGCAAGAAGTAGAAATCAAATAACACGATTTGGTAAATTTATGGATCCTTTGGCAGACAAACTGTTGGTTACAGCAGCT
TTAATATCATTAGTAGAATTACAGGTTATTTCTACATGGGTTGCAATGATTATTATAGCAAGGGAATTTGCCGTAACAGG
TCTTAGAGCAGTAGCAGCTTCTGAGGGTATAGTAATTGCTGCAAGTCCTTTGGGAAAAGCAAAAACTGTTACACAAATTA
TAGCTATTATAATAGCACTTATAAATTTAAATAATATTAACATATTATCTATTCCAAGTAACTATATTTCTAGTCTTACT
AATATAACCATGGGTGCTGCAGTTATTATAACTATCATTTCTGGAATAGATTATTTTGTGAAAAATAAAGAAGCTATAAA
AATAGATAAATAA

Upstream 100 bases:

>100_bases
ATAGATGGTGCAATTTATTTTAAATGTGATAAAATATTAAATATAGGTGAGATGGTATGTATCAAAATATTAGAGACCTT
AGAATATGATCTAATAGGAG

Downstream 100 bases:

>100_bases
TTATTTAGAGTTGTTTTAAAAAAATATATCTGTCAATAATACAAATAAAGTTCCCTATAGGGAACTTTATTTAATGAACA
ACGAACAGTGAATAATGAGT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MYVMNLANKLTIIRIFLVPVFLIFIAINDIPYGKTIATAIFIIAALTDKLDGYIARSRNQITRFGKFMDPLADKLLVTAA
LISLVELQVISTWVAMIIIAREFAVTGLRAVAASEGIVIAASPLGKAKTVTQIIAIIIALINLNNINILSIPSNYISSLT
NITMGAAVIITIISGIDYFVKNKEAIKIDK

Sequences:

>Translated_190_residues
MYVMNLANKLTIIRIFLVPVFLIFIAINDIPYGKTIATAIFIIAALTDKLDGYIARSRNQITRFGKFMDPLADKLLVTAA
LISLVELQVISTWVAMIIIAREFAVTGLRAVAASEGIVIAASPLGKAKTVTQIIAIIIALINLNNINILSIPSNYISSLT
NITMGAAVIITIISGIDYFVKNKEAIKIDK
>Mature_190_residues
MYVMNLANKLTIIRIFLVPVFLIFIAINDIPYGKTIATAIFIIAALTDKLDGYIARSRNQITRFGKFMDPLADKLLVTAA
LISLVELQVISTWVAMIIIAREFAVTGLRAVAASEGIVIAASPLGKAKTVTQIIAIIIALINLNNINILSIPSNYISSLT
NITMGAAVIITIISGIDYFVKNKEAIKIDK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=147, Percent_Identity=39.4557823129252, Blast_Score=94, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24650130, Length=106, Percent_Identity=35.8490566037736, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24650126, Length=106, Percent_Identity=35.8490566037736, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24650128, Length=106, Percent_Identity=35.8490566037736, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20621; Mature: 20621

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVMNLANKLTIIRIFLVPVFLIFIAINDIPYGKTIATAIFIIAALTDKLDGYIARSRNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITRFGKFMDPLADKLLVTAALISLVELQVISTWVAMIIIAREFAVTGLRAVAASEGIVIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ASPLGKAKTVTQIIAIIIALINLNNINILSIPSNYISSLTNITMGAAVIITIISGIDYFV
ECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNKEAIKIDK
CCCCEEECCC
>Mature Secondary Structure
MYVMNLANKLTIIRIFLVPVFLIFIAINDIPYGKTIATAIFIIAALTDKLDGYIARSRNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITRFGKFMDPLADKLLVTAALISLVELQVISTWVAMIIIAREFAVTGLRAVAASEGIVIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ASPLGKAKTVTQIIAIIIALINLNNINILSIPSNYISSLTNITMGAAVIITIISGIDYFV
ECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNKEAIKIDK
CCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]