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The map label for this gene is ftsK

Identifier: 28210971

GI number: 28210971

Start: 1379043

End: 1381274

Strand: Direct

Name: ftsK

Synonym: CTC01286

Alternate gene names: 28210971

Gene position: 1379043-1381274 (Clockwise)

Preceding gene: 28210969

Following gene: 28210972

Centisome position: 49.26

GC content: 29.84

Gene sequence:

>2232_bases
GTGGCAAAGAAAAAAAAGCAAAAAACTATTAAACTAGATGCTGAAATTAAAGGGATATTATTTATAACTATAGGTGTACT
TTCTCTTATAAGTATTATGTCCTCTTCAAATTCAGGAATTATTGGTAAAATGTCAAAGAAAATTCTTGTATTTATATTTG
GGTTAGGAGCTTTTATATTTCCATTCTTTATAATATTTGTAGGTGTATGTCTAATACTTAAAAAAGGTAAAGTAACATAT
AGTGGAAAGTTTTATGGAATAGTTTTATTTATTTTAAATACACTATTTTGTTTACATATAGGAGATATAGTTACAAAAGG
CTTGGATAGAAGTTTTTTTCAAGGAATTGTGGATATTTATAACTCGGAAACTTTTTTACATGGTGGGGTAATTTCATATA
TAGTGGATCTTCCCTTATATAAGCTTTTTGGCAAATGGGGAACTTTTGTAATATTTATTTCTATATATGTTATATGTTTT
ATATTAATAAGCCAAATATCTTTATACAGCATAATAAGTAAGTTTAAACTTAAAAAAGAAAAAAGGAGAAAAGAAAAAAA
TATAGAAATAAAAGAGGATGTTCAAGATGAAGTTAAATTTACAGAGATTAAAGATTCGGAGGAGATACCAGAAGAAAAAA
TAATTAATAGAATAAAAATAATAGATTTTATAAAAAATACCAATATAGAAGAAAATGATGATACAAAAGAAAATAAGCCT
ATACAAAAAGGAAAAGATAGCAATAATATTCAAGGAGAAAAAGATATAAATAAAGAGTTGGAAGAGGAAATGAGCAAAGC
GGCTTTAAAAACTATAGATTATGAATTTCCATCTATAGATTTATTAAATGATAATAAATCTATAAAACTAAAGAAAGAAG
ATAAAAAGGAGCTACTTAATAATGCCAATAAACTTGAAGAAACTCTAACAAGTTTTGGGGTGGAAGCTAAAGTAACTCAG
GTTACAAAAGGACCTTCAGTAACCAGATTTGAGCTTCAACCAAGTGTTGGGGTTAAAGTAAGTAAAATTGTACACTTAGC
AGATGATATAGCCTTAAATTTAGCCGCTCAAGATGTAAGAATTGAAGCACCAATACCAGGTAAGTCAGCTGTGGGAATAG
AGGTGCCTAATAGAGAATTAACACCAGTTTATTTAAAAGAGGTTTTAGACTCTAATGAATTTAAGAATTGTAATAAAAAT
TTAGCTTTTGCCATAGGAAAAGATATAGCGGGTAATTGTGTTGTTTCAGATTTAAGTAAAATGCCGCATTTATTAATAGC
AGGGGCTACAGGTTCTGGTAAAAGTGTTTGTATAAATACTTTAATAATAAGCTTAATATATAAGTATTCTCCTGAAGATG
TAAAACTGCTTATGGTAGATCCTAAAGTAGTAGAACTTAATATATACAATGATATACCACATCTACTTATTCCTGTAGTT
ACAGAACCTAAAAAAGCAGCAGGTGCCCTGTATTGGGCAGTAAATGAAATGACTAGAAGATATAAGTTATTTGCAGAAAC
CAATGTAAGAAACATTGAAAGTTATAATGAGCTACTTAAGAAAGGGAAGGGAGTAGAAAAACTTCCTTTAATAGTTATAG
TTATAGATGAATTAGCAGATTTAATGATGGTATGTCCTAATGATATAGAAGACTATATAGGAAGATTAGCTCAAATGGCA
AGAGCTGCAGGTATGCATTTAGTTATAGCCACTCAAAGACCTTCTGTAGATGTAATAACAGGAGTCATAAAAGCTAATAT
ACCTTCTAGAATTTCCTTTGCAGTTTCAAGTCAGATAGATTCAAGAACCATATTGGATATGGGAGGAGCAGAAAAACTAT
TAGGAAAAGGAGACATGCTTTTTTATCCCTCTGGAGAATCAAAACCTATGAGAGTACAAGGGGCATTCATATCTGAAGAA
GAAGTTGAAAAGGTAGTAGGTTTTATAAAAGAGAAGCAATGTGGGGAAGTAGAATATGAAGATAGCATAATAGATGAAAT
AAACACTTCAATTGAAATAAATAACGAGGATAGAGACGAACTTTTAGAAGAGGCCATAAAAATTGTAGTAGATGTAGATC
AAGCGTCAACTTCACTATTGCAAAGAAAGTTAAGAATAGGTTATAATAGGGCAGCTAGAATAATGGACCAAATGGAGGAG
AGGGGTATTATATCCCAAAAAGATGGAAGTAAGCCAAGACAGGTATTAATAAGCAAAGATGATATTGTCTAA

Upstream 100 bases:

>100_bases
TAGTTGTACTATGGAAAACCTGTTCAGCAAAGCTGAATATAAAGATTTTATACAATCAAAAAATTATTCATTATTCATTA
ACTAAAGGGGGAGGGATAAA

Downstream 100 bases:

>100_bases
GAAGTTTAAGGAGGAGTAAAATGACAAAAATAAAATATGGAGTAGTTAGTTTAGGTTGCGATAAAAATAGAATTGACTCT
GAGGTAATGATAAATGAGAT

Product: cell division protein ftsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 743; Mature: 742

Protein sequence:

>743_residues
MAKKKKQKTIKLDAEIKGILFITIGVLSLISIMSSSNSGIIGKMSKKILVFIFGLGAFIFPFFIIFVGVCLILKKGKVTY
SGKFYGIVLFILNTLFCLHIGDIVTKGLDRSFFQGIVDIYNSETFLHGGVISYIVDLPLYKLFGKWGTFVIFISIYVICF
ILISQISLYSIISKFKLKKEKRRKEKNIEIKEDVQDEVKFTEIKDSEEIPEEKIINRIKIIDFIKNTNIEENDDTKENKP
IQKGKDSNNIQGEKDINKELEEEMSKAALKTIDYEFPSIDLLNDNKSIKLKKEDKKELLNNANKLEETLTSFGVEAKVTQ
VTKGPSVTRFELQPSVGVKVSKIVHLADDIALNLAAQDVRIEAPIPGKSAVGIEVPNRELTPVYLKEVLDSNEFKNCNKN
LAFAIGKDIAGNCVVSDLSKMPHLLIAGATGSGKSVCINTLIISLIYKYSPEDVKLLMVDPKVVELNIYNDIPHLLIPVV
TEPKKAAGALYWAVNEMTRRYKLFAETNVRNIESYNELLKKGKGVEKLPLIVIVIDELADLMMVCPNDIEDYIGRLAQMA
RAAGMHLVIATQRPSVDVITGVIKANIPSRISFAVSSQIDSRTILDMGGAEKLLGKGDMLFYPSGESKPMRVQGAFISEE
EVEKVVGFIKEKQCGEVEYEDSIIDEINTSIEINNEDRDELLEEAIKIVVDVDQASTSLLQRKLRIGYNRAARIMDQMEE
RGIISQKDGSKPRQVLISKDDIV

Sequences:

>Translated_743_residues
MAKKKKQKTIKLDAEIKGILFITIGVLSLISIMSSSNSGIIGKMSKKILVFIFGLGAFIFPFFIIFVGVCLILKKGKVTY
SGKFYGIVLFILNTLFCLHIGDIVTKGLDRSFFQGIVDIYNSETFLHGGVISYIVDLPLYKLFGKWGTFVIFISIYVICF
ILISQISLYSIISKFKLKKEKRRKEKNIEIKEDVQDEVKFTEIKDSEEIPEEKIINRIKIIDFIKNTNIEENDDTKENKP
IQKGKDSNNIQGEKDINKELEEEMSKAALKTIDYEFPSIDLLNDNKSIKLKKEDKKELLNNANKLEETLTSFGVEAKVTQ
VTKGPSVTRFELQPSVGVKVSKIVHLADDIALNLAAQDVRIEAPIPGKSAVGIEVPNRELTPVYLKEVLDSNEFKNCNKN
LAFAIGKDIAGNCVVSDLSKMPHLLIAGATGSGKSVCINTLIISLIYKYSPEDVKLLMVDPKVVELNIYNDIPHLLIPVV
TEPKKAAGALYWAVNEMTRRYKLFAETNVRNIESYNELLKKGKGVEKLPLIVIVIDELADLMMVCPNDIEDYIGRLAQMA
RAAGMHLVIATQRPSVDVITGVIKANIPSRISFAVSSQIDSRTILDMGGAEKLLGKGDMLFYPSGESKPMRVQGAFISEE
EVEKVVGFIKEKQCGEVEYEDSIIDEINTSIEINNEDRDELLEEAIKIVVDVDQASTSLLQRKLRIGYNRAARIMDQMEE
RGIISQKDGSKPRQVLISKDDIV
>Mature_742_residues
AKKKKQKTIKLDAEIKGILFITIGVLSLISIMSSSNSGIIGKMSKKILVFIFGLGAFIFPFFIIFVGVCLILKKGKVTYS
GKFYGIVLFILNTLFCLHIGDIVTKGLDRSFFQGIVDIYNSETFLHGGVISYIVDLPLYKLFGKWGTFVIFISIYVICFI
LISQISLYSIISKFKLKKEKRRKEKNIEIKEDVQDEVKFTEIKDSEEIPEEKIINRIKIIDFIKNTNIEENDDTKENKPI
QKGKDSNNIQGEKDINKELEEEMSKAALKTIDYEFPSIDLLNDNKSIKLKKEDKKELLNNANKLEETLTSFGVEAKVTQV
TKGPSVTRFELQPSVGVKVSKIVHLADDIALNLAAQDVRIEAPIPGKSAVGIEVPNRELTPVYLKEVLDSNEFKNCNKNL
AFAIGKDIAGNCVVSDLSKMPHLLIAGATGSGKSVCINTLIISLIYKYSPEDVKLLMVDPKVVELNIYNDIPHLLIPVVT
EPKKAAGALYWAVNEMTRRYKLFAETNVRNIESYNELLKKGKGVEKLPLIVIVIDELADLMMVCPNDIEDYIGRLAQMAR
AAGMHLVIATQRPSVDVITGVIKANIPSRISFAVSSQIDSRTILDMGGAEKLLGKGDMLFYPSGESKPMRVQGAFISEEE
VEKVVGFIKEKQCGEVEYEDSIIDEINTSIEINNEDRDELLEEAIKIVVDVDQASTSLLQRKLRIGYNRAARIMDQMEER
GIISQKDGSKPRQVLISKDDIV

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=487, Percent_Identity=47.6386036960986, Blast_Score=430, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_CLOTE (Q895I8)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781915.1
- ProteinModelPortal:   Q895I8
- SMR:   Q895I8
- GeneID:   1059362
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC01286
- NMPDR:   fig|212717.1.peg.1137
- HOGENOM:   HBG662140
- OMA:   AAALNWA
- ProtClustDB:   CLSK882943
- BioCyc:   CTET212717:CTC_01286-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 83170; Mature: 83039

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcea35bc)-; HASH(0xe4b3898)-; HASH(0xd9bc850)-; HASH(0xb94cbdc)-; HASH(0xe3263c4)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKKKQKTIKLDAEIKGILFITIGVLSLISIMSSSNSGIIGKMSKKILVFIFGLGAFIF
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
PFFIIFVGVCLILKKGKVTYSGKFYGIVLFILNTLFCLHIGDIVTKGLDRSFFQGIVDIY
HHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
NSETFLHGGVISYIVDLPLYKLFGKWGTFVIFISIYVICFILISQISLYSIISKFKLKKE
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRRKEKNIEIKEDVQDEVKFTEIKDSEEIPEEKIINRIKIIDFIKNTNIEENDDTKENKP
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
IQKGKDSNNIQGEKDINKELEEEMSKAALKTIDYEFPSIDLLNDNKSIKLKKEDKKELLN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECHHHHHHHH
NANKLEETLTSFGVEAKVTQVTKGPSVTRFELQPSVGVKVSKIVHLADDIALNLAAQDVR
HHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEECCEE
IEAPIPGKSAVGIEVPNRELTPVYLKEVLDSNEFKNCNKNLAFAIGKDIAGNCVVSDLSK
EECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHC
MPHLLIAGATGSGKSVCINTLIISLIYKYSPEDVKLLMVDPKVVELNIYNDIPHLLIPVV
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCCEEECC
TEPKKAAGALYWAVNEMTRRYKLFAETNVRNIESYNELLKKGKGVEKLPLIVIVIDELAD
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHH
LMMVCPNDIEDYIGRLAQMARAAGMHLVIATQRPSVDVITGVIKANIPSRISFAVSSQID
HHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEHHHHCCCC
SRTILDMGGAEKLLGKGDMLFYPSGESKPMRVQGAFISEEEVEKVVGFIKEKQCGEVEYE
CCEEECCCCHHHHHCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCH
DSIIDEINTSIEINNEDRDELLEEAIKIVVDVDQASTSLLQRKLRIGYNRAARIMDQMEE
HHHHHHCCCEEEECCCCHHHHHHHHHHHEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHH
RGIISQKDGSKPRQVLISKDDIV
CCCCCCCCCCCCCEEEECCCCCH
>Mature Secondary Structure 
AKKKKQKTIKLDAEIKGILFITIGVLSLISIMSSSNSGIIGKMSKKILVFIFGLGAFIF
CCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
PFFIIFVGVCLILKKGKVTYSGKFYGIVLFILNTLFCLHIGDIVTKGLDRSFFQGIVDIY
HHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
NSETFLHGGVISYIVDLPLYKLFGKWGTFVIFISIYVICFILISQISLYSIISKFKLKKE
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRRKEKNIEIKEDVQDEVKFTEIKDSEEIPEEKIINRIKIIDFIKNTNIEENDDTKENKP
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
IQKGKDSNNIQGEKDINKELEEEMSKAALKTIDYEFPSIDLLNDNKSIKLKKEDKKELLN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECHHHHHHHH
NANKLEETLTSFGVEAKVTQVTKGPSVTRFELQPSVGVKVSKIVHLADDIALNLAAQDVR
HHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEECCEE
IEAPIPGKSAVGIEVPNRELTPVYLKEVLDSNEFKNCNKNLAFAIGKDIAGNCVVSDLSK
EECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHC
MPHLLIAGATGSGKSVCINTLIISLIYKYSPEDVKLLMVDPKVVELNIYNDIPHLLIPVV
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCCEEECC
TEPKKAAGALYWAVNEMTRRYKLFAETNVRNIESYNELLKKGKGVEKLPLIVIVIDELAD
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHH
LMMVCPNDIEDYIGRLAQMARAAGMHLVIATQRPSVDVITGVIKANIPSRISFAVSSQID
HHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEHHHHCCCC
SRTILDMGGAEKLLGKGDMLFYPSGESKPMRVQGAFISEEEVEKVVGFIKEKQCGEVEYE
CCEEECCCCHHHHHCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCH
DSIIDEINTSIEINNEDRDELLEEAIKIVVDVDQASTSLLQRKLRIGYNRAARIMDQMEE
HHHHHHCCCEEEECCCCHHHHHHHHHHHEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHH
RGIISQKDGSKPRQVLISKDDIV
CCCCCCCCCCCCCEEEECCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12552129