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The map label for this gene is yycF [H]

Identifier: 28210824

GI number: 28210824

Start: 1195145

End: 1195843

Strand: Direct

Name: yycF [H]

Synonym: CTC01130

Alternate gene names: 28210824

Gene position: 1195145-1195843 (Clockwise)

Preceding gene: 161486846

Following gene: 28210825

Centisome position: 42.7

GC content: 28.9

Gene sequence:

>699_bases
ATGTCACAAGATAAGATTTTAATAGTGGATGATGAAGAGCATATTAGAGAACTTCTTAGATATAATTTAGAAAAAGAAGG
CTATAAAATTTTTTGTGCTGAAAATGGAAAAGAAGCTTTAGAAATAGCTAAAGAAAAAAAACCTACACTAATTTTACTGG
ATGTCATGTTACCACAAATGGATGGGTATGACGTATGCAAAGAAATAAGAAAAGATAATTCTATATCCACTACACCCATT
ATAATGATAACTGCTAAAGGTGAAGAATTAGATAAGGTGTTAGGATTAGAACTTGGTGCAGATGATTATATAACAAAACC
CTTTTCCATTAGGGAATTGATTGCCAGAATAAAAGCTGTACTGAGAAGAACTTTATTAAAGAGTACAGAGGAACCTTTTA
AATTTGAAGGTTTAAAAATGGATTTTGAAAAACATGAAGTAATGAAAGACGGGGAAAAAGTTGATTTAACCCTTAAAGAA
TTTCAATTGTTAGAAATACTTATTAAAAATAAAGGAAGAGTATTAACTAGAGAATATTTATTAGATAAAATATGGGGATA
TGAATATATAGGAGAAACTAGGACAGTAGACGTACATATAAGACATTTAAGACAGAAGGTAGAGGATGATGATAAAAACC
CTAAGTATATAGAAACTATTAGAGGAGTGGGATATAGGTTCAATCTAAATATAAATTAA

Upstream 100 bases:

>100_bases
ATATGTTAGATATGTTAAATGTATTTTGAATATGTAAATTAATATATTTAAATATGTTAGAATTAAATTAGACAAAATAA
ATAGCCATGGAGGGTATAGT

Downstream 100 bases:

>100_bases
GGGTGGTAAAATGAAAAAAAGATTAATGAGGCATATGTTAGCTACATTAACTTTTAGCATGATTTTTGTTATTACTTTTT
TTGCAGTTATAACAAATTAT

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSQDKILIVDDEEHIRELLRYNLEKEGYKIFCAENGKEALEIAKEKKPTLILLDVMLPQMDGYDVCKEIRKDNSISTTPI
IMITAKGEELDKVLGLELGADDYITKPFSIRELIARIKAVLRRTLLKSTEEPFKFEGLKMDFEKHEVMKDGEKVDLTLKE
FQLLEILIKNKGRVLTREYLLDKIWGYEYIGETRTVDVHIRHLRQKVEDDDKNPKYIETIRGVGYRFNLNIN

Sequences:

>Translated_232_residues
MSQDKILIVDDEEHIRELLRYNLEKEGYKIFCAENGKEALEIAKEKKPTLILLDVMLPQMDGYDVCKEIRKDNSISTTPI
IMITAKGEELDKVLGLELGADDYITKPFSIRELIARIKAVLRRTLLKSTEEPFKFEGLKMDFEKHEVMKDGEKVDLTLKE
FQLLEILIKNKGRVLTREYLLDKIWGYEYIGETRTVDVHIRHLRQKVEDDDKNPKYIETIRGVGYRFNLNIN
>Mature_231_residues
SQDKILIVDDEEHIRELLRYNLEKEGYKIFCAENGKEALEIAKEKKPTLILLDVMLPQMDGYDVCKEIRKDNSISTTPII
MITAKGEELDKVLGLELGADDYITKPFSIRELIARIKAVLRRTLLKSTEEPFKFEGLKMDFEKHEVMKDGEKVDLTLKEF
QLLEILIKNKGRVLTREYLLDKIWGYEYIGETRTVDVHIRHLRQKVEDDDKNPKYIETIRGVGYRFNLNIN

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=44.1964285714286, Blast_Score=193, Evalue=8e-51,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=39.8230088495575, Blast_Score=176, Evalue=9e-46,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=40.174672489083, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=42.2222222222222, Blast_Score=170, Evalue=7e-44,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=38.9140271493213, Blast_Score=167, Evalue=4e-43,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=41.0714285714286, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=39.7379912663755, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=35.8407079646018, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=37.4468085106383, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=34.8017621145374, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=33.0357142857143, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=31.858407079646, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=34.5132743362832, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=31.063829787234, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788550, Length=110, Percent_Identity=39.0909090909091, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790299, Length=118, Percent_Identity=33.8983050847458, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788191, Length=110, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790437, Length=134, Percent_Identity=33.5820895522388, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=113, Percent_Identity=36.283185840708, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27179; Mature: 27048

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDKILIVDDEEHIRELLRYNLEKEGYKIFCAENGKEALEIAKEKKPTLILLDVMLPQM
CCCCCEEEECCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCC
DGYDVCKEIRKDNSISTTPIIMITAKGEELDKVLGLELGADDYITKPFSIRELIARIKAV
CCHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
LRRTLLKSTEEPFKFEGLKMDFEKHEVMKDGEKVDLTLKEFQLLEILIKNKGRVLTREYL
HHHHHHHCCCCCCEECCEEECHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHH
LDKIWGYEYIGETRTVDVHIRHLRQKVEDDDKNPKYIETIRGVGYRFNLNIN
HHHHCCHHHCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEECC
>Mature Secondary Structure 
SQDKILIVDDEEHIRELLRYNLEKEGYKIFCAENGKEALEIAKEKKPTLILLDVMLPQM
CCCCEEEECCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCC
DGYDVCKEIRKDNSISTTPIIMITAKGEELDKVLGLELGADDYITKPFSIRELIARIKAV
CCHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
LRRTLLKSTEEPFKFEGLKMDFEKHEVMKDGEKVDLTLKEFQLLEILIKNKGRVLTREYL
HHHHHHHCCCCCCEECCEEECHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHH
LDKIWGYEYIGETRTVDVHIRHLRQKVEDDDKNPKYIETIRGVGYRFNLNIN
HHHHCCHHHCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]