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The map label for this gene is phoR [H]

Identifier: 28210825

GI number: 28210825

Start: 1195854

End: 1197569

Strand: Direct

Name: phoR [H]

Synonym: CTC01131

Alternate gene names: 28210825

Gene position: 1195854-1197569 (Clockwise)

Preceding gene: 28210824

Following gene: 28210826

Centisome position: 42.72

GC content: 27.51

Gene sequence:

>1716_bases
ATGAAAAAAAGATTAATGAGGCATATGTTAGCTACATTAACTTTTAGCATGATTTTTGTTATTACTTTTTTTGCAGTTAT
AACAAATTATAAATACATGGAAAATAGTAAAGCTATGTTAAAAGTCAATAACGAAATTGTAGTGAAAATGTTGAAGTCCA
ATGATGTAAAAGATAAAAAGACTATTGTACCCTATATATTTAATGATAGTGATATAAGGATAAGTTGTGTAGATCAAAAT
GATAAATTAATATTTGATTCACATTTGAAAAATCATGATGGAGAGTTCTATGGTAAAAGAGAGGAGATAATAGAGGCTAG
GGAAAAGGGAGAAGGATTTAAAATTAGATACAGTCAAAGTGAAAATATGAATACTATGTATTTTGCCAAGCTATTAGAAA
ATGGATTCATAATTAGAACTTCCACAAGTCTTGGTGATGTTAGTATTTTACGAGGAAAATACTTTATATATTATTTAATT
ATAATCATACTTTCTACTCTAGGAGCTTTCATTTTTGCATCAAAATTATCTTCAAGCATTGTTAATCCTATAAAAAAATT
AGAATTTATAACTTCTAGAATAGCAGCAGGAGAATTAGATAGAAGAGTAAATATAAATTCTAAGGATGAAATAGGTCAGT
TAAGTAATACTTTTAACAATATGGCAGATAAACTTCAATACACAATAAATGATAGTATAGAAAAACAAAATAAACTAGAA
GCTATTTTAAAAAGTATGGATAATGGAGTAATTGCTGTAGATAAAGATTTTAAAATTATAATGATAAATCCCTATGCTAA
AGAAATCTTTAGCATAGAACAAGATATTATAGGAGAAAATCTACTAGATAAAATAAAAAGTTATGAATTAAAAGAGATAT
TTAAAGAAGATAATATAGAGGACTATAGAGAAGTAAAAATCCTTTCGCCAAAAGAAAAGAATTTGAGAGTAAAAACTACA
GACATAAAAATAGGAAAACAGTTAATAGGTACAGTAGCAGTAGTACAAGATGTTACAGAAATAAAAAAGCTAGAGAATAT
AAGATCTCAGTTTGTGGCAAATGTTACTCATGAATTAAAAACACCTCTAACATCTATAAGGGGTTTTGCTGAAACCTTAA
AATATGTAGAAGATAGGGAAACTAAGGATAAGTTTTTAAATATAATAAATGATGAATCAGATAGGCTTACAAGACTTATA
AATGATATACTAGCCCTTTCCCATATAGAAAATAGTAATAGTATGAAGCTAGAAAATATATCTATAAATGAAATGCTAGA
GGATATAGTATATTTAATGGAGAATTCAGCAAAGGACAAAAATATAGAACTATTTATTGTAGGAGACAAGATGCAGCCTA
TAAAAGGAGATAGAGATAGATTTAAACAAATGATGATAAACCTAGTGGATAATGGTATTAAATATACTGAAGAAGGCGGT
AAGGTTTATATAGGAGCCAAAAAAGAAGATAATAATTGTATTGTATGGGTAGAAGACACAGGAGTAGGAATTTCTAAAGA
ACATGTAGAAAGACTATTCGAAAGATTCTATAGGGTAGATAAAGCCAGAAGTAGAAGTCAAGGAGGTACGGGTTTAGGCT
TAGCCATAGTTAAACACATAGTTTTAGGCTTTGGCGGAACTATTAATATAGAAAGTGAAGAGGGAAAAGGAAGTAAATTT
ATTATAAGAATACCTATAAAATCAAATTTAGTTTAG

Upstream 100 bases:

>100_bases
AGACAGAAGGTAGAGGATGATGATAAAAACCCTAAGTATATAGAAACTATTAGAGGAGTGGGATATAGGTTCAATCTAAA
TATAAATTAAGGGTGGTAAA

Downstream 100 bases:

>100_bases
AGGTTGCAAAAAGCAGCCTCTTTTTAATTTGTAAAAATGGAGTTAATTTATTTTAACAGAGGAGTAATATGTATTTAACT
TAAGTTTATTATAATTTACG

Product: phosphate regulon sensor protein phoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MKKRLMRHMLATLTFSMIFVITFFAVITNYKYMENSKAMLKVNNEIVVKMLKSNDVKDKKTIVPYIFNDSDIRISCVDQN
DKLIFDSHLKNHDGEFYGKREEIIEAREKGEGFKIRYSQSENMNTMYFAKLLENGFIIRTSTSLGDVSILRGKYFIYYLI
IIILSTLGAFIFASKLSSSIVNPIKKLEFITSRIAAGELDRRVNINSKDEIGQLSNTFNNMADKLQYTINDSIEKQNKLE
AILKSMDNGVIAVDKDFKIIMINPYAKEIFSIEQDIIGENLLDKIKSYELKEIFKEDNIEDYREVKILSPKEKNLRVKTT
DIKIGKQLIGTVAVVQDVTEIKKLENIRSQFVANVTHELKTPLTSIRGFAETLKYVEDRETKDKFLNIINDESDRLTRLI
NDILALSHIENSNSMKLENISINEMLEDIVYLMENSAKDKNIELFIVGDKMQPIKGDRDRFKQMMINLVDNGIKYTEEGG
KVYIGAKKEDNNCIVWVEDTGVGISKEHVERLFERFYRVDKARSRSQGGTGLGLAIVKHIVLGFGGTINIESEEGKGSKF
IIRIPIKSNLV

Sequences:

>Translated_571_residues
MKKRLMRHMLATLTFSMIFVITFFAVITNYKYMENSKAMLKVNNEIVVKMLKSNDVKDKKTIVPYIFNDSDIRISCVDQN
DKLIFDSHLKNHDGEFYGKREEIIEAREKGEGFKIRYSQSENMNTMYFAKLLENGFIIRTSTSLGDVSILRGKYFIYYLI
IIILSTLGAFIFASKLSSSIVNPIKKLEFITSRIAAGELDRRVNINSKDEIGQLSNTFNNMADKLQYTINDSIEKQNKLE
AILKSMDNGVIAVDKDFKIIMINPYAKEIFSIEQDIIGENLLDKIKSYELKEIFKEDNIEDYREVKILSPKEKNLRVKTT
DIKIGKQLIGTVAVVQDVTEIKKLENIRSQFVANVTHELKTPLTSIRGFAETLKYVEDRETKDKFLNIINDESDRLTRLI
NDILALSHIENSNSMKLENISINEMLEDIVYLMENSAKDKNIELFIVGDKMQPIKGDRDRFKQMMINLVDNGIKYTEEGG
KVYIGAKKEDNNCIVWVEDTGVGISKEHVERLFERFYRVDKARSRSQGGTGLGLAIVKHIVLGFGGTINIESEEGKGSKF
IIRIPIKSNLV
>Mature_571_residues
MKKRLMRHMLATLTFSMIFVITFFAVITNYKYMENSKAMLKVNNEIVVKMLKSNDVKDKKTIVPYIFNDSDIRISCVDQN
DKLIFDSHLKNHDGEFYGKREEIIEAREKGEGFKIRYSQSENMNTMYFAKLLENGFIIRTSTSLGDVSILRGKYFIYYLI
IIILSTLGAFIFASKLSSSIVNPIKKLEFITSRIAAGELDRRVNINSKDEIGQLSNTFNNMADKLQYTINDSIEKQNKLE
AILKSMDNGVIAVDKDFKIIMINPYAKEIFSIEQDIIGENLLDKIKSYELKEIFKEDNIEDYREVKILSPKEKNLRVKTT
DIKIGKQLIGTVAVVQDVTEIKKLENIRSQFVANVTHELKTPLTSIRGFAETLKYVEDRETKDKFLNIINDESDRLTRLI
NDILALSHIENSNSMKLENISINEMLEDIVYLMENSAKDKNIELFIVGDKMQPIKGDRDRFKQMMINLVDNGIKYTEEGG
KVYIGAKKEDNNCIVWVEDTGVGISKEHVERLFERFYRVDKARSRSQGGTGLGLAIVKHIVLGFGGTINIESEEGKGSKF
IIRIPIKSNLV

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=325, Percent_Identity=32, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=37.1681415929204, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1786783, Length=275, Percent_Identity=28.3636363636364, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788549, Length=379, Percent_Identity=25.3298153034301, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=36.322869955157, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=30.8333333333333, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1788393, Length=244, Percent_Identity=29.5081967213115, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790346, Length=261, Percent_Identity=29.5019157088123, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=31.2236286919831, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI48994928, Length=259, Percent_Identity=27.7992277992278, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=29.9212598425197, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=29.4685990338164, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787894, Length=245, Percent_Identity=28.1632653061224, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=28.5087719298246, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1789808, Length=232, Percent_Identity=28.8793103448276, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=25.8474576271186, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788279, Length=205, Percent_Identity=30.2439024390244, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790567, Length=341, Percent_Identity=23.7536656891496, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789403, Length=212, Percent_Identity=27.3584905660377, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790300, Length=351, Percent_Identity=23.0769230769231, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790551, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787374, Length=201, Percent_Identity=25.3731343283582, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65482; Mature: 65482

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRLMRHMLATLTFSMIFVITFFAVITNYKYMENSKAMLKVNNEIVVKMLKSNDVKDKK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCHHHHHHHHCCCCCCCC
TIVPYIFNDSDIRISCVDQNDKLIFDSHLKNHDGEFYGKREEIIEAREKGEGFKIRYSQS
EEEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCC
ENMNTMYFAKLLENGFIIRTSTSLGDVSILRGKYFIYYLIIIILSTLGAFIFASKLSSSI
CCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNPIKKLEFITSRIAAGELDRRVNINSKDEIGQLSNTFNNMADKLQYTINDSIEKQNKLE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEHHCHHHHHHHHHH
AILKSMDNGVIAVDKDFKIIMINPYAKEIFSIEQDIIGENLLDKIKSYELKEIFKEDNIE
HHHHHCCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DYREVKILSPKEKNLRVKTTDIKIGKQLIGTVAVVQDVTEIKKLENIRSQFVANVTHELK
CHHHEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLTSIRGFAETLKYVEDRETKDKFLNIINDESDRLTRLINDILALSHIENSNSMKLENI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECC
SINEMLEDIVYLMENSAKDKNIELFIVGDKMQPIKGDRDRFKQMMINLVDNGIKYTEEGG
CHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCC
KVYIGAKKEDNNCIVWVEDTGVGISKEHVERLFERFYRVDKARSRSQGGTGLGLAIVKHI
EEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VLGFGGTINIESEEGKGSKFIIRIPIKSNLV
HHCCCCEEEEECCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKKRLMRHMLATLTFSMIFVITFFAVITNYKYMENSKAMLKVNNEIVVKMLKSNDVKDKK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCHHHHHHHHCCCCCCCC
TIVPYIFNDSDIRISCVDQNDKLIFDSHLKNHDGEFYGKREEIIEAREKGEGFKIRYSQS
EEEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCC
ENMNTMYFAKLLENGFIIRTSTSLGDVSILRGKYFIYYLIIIILSTLGAFIFASKLSSSI
CCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNPIKKLEFITSRIAAGELDRRVNINSKDEIGQLSNTFNNMADKLQYTINDSIEKQNKLE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEHHCHHHHHHHHHH
AILKSMDNGVIAVDKDFKIIMINPYAKEIFSIEQDIIGENLLDKIKSYELKEIFKEDNIE
HHHHHCCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DYREVKILSPKEKNLRVKTTDIKIGKQLIGTVAVVQDVTEIKKLENIRSQFVANVTHELK
CHHHEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLTSIRGFAETLKYVEDRETKDKFLNIINDESDRLTRLINDILALSHIENSNSMKLENI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECC
SINEMLEDIVYLMENSAKDKNIELFIVGDKMQPIKGDRDRFKQMMINLVDNGIKYTEEGG
CHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCC
KVYIGAKKEDNNCIVWVEDTGVGISKEHVERLFERFYRVDKARSRSQGGTGLGLAIVKHI
EEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VLGFGGTINIESEEGKGSKFIIRIPIKSNLV
HHCCCCEEEEECCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]