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The map label for this gene is hprK

Identifier: 28210715

GI number: 28210715

Start: 1079898

End: 1080815

Strand: Direct

Name: hprK

Synonym: CTC01010

Alternate gene names: 28210715

Gene position: 1079898-1080815 (Clockwise)

Preceding gene: 28210714

Following gene: 28210716

Centisome position: 38.58

GC content: 31.92

Gene sequence:

>918_bases
ATGGGAGTTTTGGTTAAAAATCTAGTAGAAGATTTAAAATTAGAAGTATTAAATAAAGGCAAAGATGATATAGAATTGAA
TATAAGCGATATAAATAGACCAGGTCTTCAATTTTCAGGATTCTATAATTATTTTGCAAATGAAAGGGTACAACTTATAG
GCAAAACTGAATGGAGTTTTTTAGATGTTATGAGTCCGGAACTTAGGAAGAAAAGAGTGGCTAAATTTTTTCAGTTTGAA
ACTCCCTGCGTAATAATTACAAGAAATTTGAAACCTCATAAAGAAGTATTAGAGAATTCAAGAAAATACAACAGATGGCT
GTTAAACACTAGTAATATATCAACGAGATTTACCAGTAAACTAATGAATTATTTAGATGAAAAATTAGCTCCGGAAACAA
GATTACACGGAGTTTTAGTGGACGTTTATGGCATAGGTATTCTTATTACTGGAGAAAGCGGTATAGGTAAAAGTGAAACG
GCTCTAGAACTTATAAAAAGAGGGCATAGATTAGTGGCAGATGATGCTGTGGATATAAAAGAAATTGAAGGAAAGCTTAT
AGGAAGTTCTCCTTATGTAACTTCTGGTATGTTAGAAGTTAGGGGGCTAGGTATTATAGATGTCCCCTCTTTATATGGTT
TAAGCTCTGTGTTAGATATAAAAACTATTGGAGTGATTATACACTTAGAACAATGGAAAAAGGATCAGGATTATGATAGA
TTAGGCATAGATGAAATTAATAGGGATATTTTAAATGTACCAGTAAGAAAAATAACTTTACCAATAAGACCTGGAAGAAA
TATTGCAGTAATAATAGAGGCAGCGGCCGCAAATTACAGATATAATCTAAATTCTAATAGTAGCCCAGTAGACACCATAG
GAGCTAGAATGAAAGAAGAGAATCTCAAGAATAAATAA

Upstream 100 bases:

>100_bases
TACTTAGATAAATATGCTAAAGCTATATCTAATGGAATACTTAAAACTATGGGTAAAATTTAAATTTTACCCTTTTCTTA
AATTATAAGGAGGAGCAATT

Downstream 100 bases:

>100_bases
AAGTTAGGATGAAGTAGCATGATTGATAAAAAAGAACTAAGGGAAAAGAGTATGGTAAAAAGAGATGGTTTATCTAAAGA
TAAAATAAATGAATATGATG

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MGVLVKNLVEDLKLEVLNKGKDDIELNISDINRPGLQFSGFYNYFANERVQLIGKTEWSFLDVMSPELRKKRVAKFFQFE
TPCVIITRNLKPHKEVLENSRKYNRWLLNTSNISTRFTSKLMNYLDEKLAPETRLHGVLVDVYGIGILITGESGIGKSET
ALELIKRGHRLVADDAVDIKEIEGKLIGSSPYVTSGMLEVRGLGIIDVPSLYGLSSVLDIKTIGVIIHLEQWKKDQDYDR
LGIDEINRDILNVPVRKITLPIRPGRNIAVIIEAAAANYRYNLNSNSSPVDTIGARMKEENLKNK

Sequences:

>Translated_305_residues
MGVLVKNLVEDLKLEVLNKGKDDIELNISDINRPGLQFSGFYNYFANERVQLIGKTEWSFLDVMSPELRKKRVAKFFQFE
TPCVIITRNLKPHKEVLENSRKYNRWLLNTSNISTRFTSKLMNYLDEKLAPETRLHGVLVDVYGIGILITGESGIGKSET
ALELIKRGHRLVADDAVDIKEIEGKLIGSSPYVTSGMLEVRGLGIIDVPSLYGLSSVLDIKTIGVIIHLEQWKKDQDYDR
LGIDEINRDILNVPVRKITLPIRPGRNIAVIIEAAAANYRYNLNSNSSPVDTIGARMKEENLKNK
>Mature_304_residues
GVLVKNLVEDLKLEVLNKGKDDIELNISDINRPGLQFSGFYNYFANERVQLIGKTEWSFLDVMSPELRKKRVAKFFQFET
PCVIITRNLKPHKEVLENSRKYNRWLLNTSNISTRFTSKLMNYLDEKLAPETRLHGVLVDVYGIGILITGESGIGKSETA
LELIKRGHRLVADDAVDIKEIEGKLIGSSPYVTSGMLEVRGLGIIDVPSLYGLSSVLDIKTIGVIIHLEQWKKDQDYDRL
GIDEINRDILNVPVRKITLPIRPGRNIAVIIEAAAANYRYNLNSNSSPVDTIGARMKEENLKNK

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_CLOTE (Q896J4)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781659.1
- ProteinModelPortal:   Q896J4
- SMR:   Q896J4
- GeneID:   1060752
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC01010
- NMPDR:   fig|212717.1.peg.881
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- BioCyc:   CTET212717:CTC_01010-MONOMER
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 34467; Mature: 34336

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: ACT_SITE 136-136 ACT_SITE 157-157 ACT_SITE 175-175 ACT_SITE 240-240

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVLVKNLVEDLKLEVLNKGKDDIELNISDINRPGLQFSGFYNYFANERVQLIGKTEWSF
CCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEECHHHHHHCCCEEEEEECCCCHH
LDVMSPELRKKRVAKFFQFETPCVIITRNLKPHKEVLENSRKYNRWLLNTSNISTRFTSK
HHHCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCHHHCEEEEECCCCHHHHHHH
LMNYLDEKLAPETRLHGVLVDVYGIGILITGESGIGKSETALELIKRGHRLVADDAVDIK
HHHHHHHHCCCCHHHHEEEEEEEEEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCHH
EIEGKLIGSSPYVTSGMLEVRGLGIIDVPSLYGLSSVLDIKTIGVIIHLEQWKKDQDYDR
HHCCEEECCCCCCCCCCEEECCCCEEECCHHHCHHHHHHHEEEEEEEEEHHCCCCCCCCC
LGIDEINRDILNVPVRKITLPIRPGRNIAVIIEAAAANYRYNLNSNSSPVDTIGARMKEE
CCHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEECCCEEEECCCCCCCHHHHHHHHHHH
NLKNK
HCCCC
>Mature Secondary Structure 
GVLVKNLVEDLKLEVLNKGKDDIELNISDINRPGLQFSGFYNYFANERVQLIGKTEWSF
CHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEECHHHHHHCCCEEEEEECCCCHH
LDVMSPELRKKRVAKFFQFETPCVIITRNLKPHKEVLENSRKYNRWLLNTSNISTRFTSK
HHHCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCHHHCEEEEECCCCHHHHHHH
LMNYLDEKLAPETRLHGVLVDVYGIGILITGESGIGKSETALELIKRGHRLVADDAVDIK
HHHHHHHHCCCCHHHHEEEEEEEEEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCHH
EIEGKLIGSSPYVTSGMLEVRGLGIIDVPSLYGLSSVLDIKTIGVIIHLEQWKKDQDYDR
HHCCEEECCCCCCCCCCEEECCCCEEECCHHHCHHHHHHHEEEEEEEEEHHCCCCCCCCC
LGIDEINRDILNVPVRKITLPIRPGRNIAVIIEAAAANYRYNLNSNSSPVDTIGARMKEE
CCHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEECCCEEEECCCCCCCHHHHHHHHHHH
NLKNK
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129