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The map label for this gene is atpD [H]

Identifier: 28210707

GI number: 28210707

Start: 1072408

End: 1073046

Strand: Direct

Name: atpD [H]

Synonym: CTC01001

Alternate gene names: 28210707

Gene position: 1072408-1073046 (Clockwise)

Preceding gene: 28210706

Following gene: 28210708

Centisome position: 38.31

GC content: 30.2

Gene sequence:

>639_bases
ATGAGATTAAATGTTAATCCTACGAGAATGGAGCTTACAAAGCTCAAAAAGAGATTGGCAACGGCAACAAGAGGACATAA
ACTTTTAAAAGATAAACAAGATGAATTAATGAGAAGATTTATTGACCTAGTAAAACATAATAACGAATTAAGAAAAAGTG
TAGAAGAGGAACTTCAAAAATCTTTAAAAGACTTTGTAATGGCAAGAGCTTTAATGTCATCAGAGTTTTTAGAGGAGGCA
ATAGTTTACCCGAAAGAAAGTATTTCATTAGAAATCGCTAAGAAAAATATTATGAGTGTAAATGTACCAATAATGAAGTT
CAAAAGAGAAATGGAAGAAGATGAGGGGAGTATATATCCATATGGGTATGTAAATACTTCTGGAGAATTGGATACAGCCA
TTGAAAAATTATATGGTATTTTACCTAAACTATTAGAACTAGCTGAGGTGGAAAAAACATGCCAACTTATGGCAGACGAA
ATTGAAAAGACAAGAAGAAGAGTAAATGCATTAGAATACATGACTATTCCTCAACTTGAAGAAACCATTAAATTTATAAT
AATGAAGTTAGATGAAAATGAAAGAGGAAATCTAACTAGACTTATGAAGGTAAAAAGTATGATGGAAGAAAAAAAATAA

Upstream 100 bases:

>100_bases
TGTCCATATTGCCAAGAACAGAACTCAAGAGAATAAGAGATGCTTATTTAGAAAAATACTTACCTAAAGAAAAAAGTAAG
GAATAAAGGGATGAAAGTCT

Downstream 100 bases:

>100_bases
AGCTGGATAATCCAGCTTTATTTTTTATTTTAAAATCTTAAAAGATTCAGAAAAATTTAAAAAAAACATATTGACAAAGT
TTTAACAAGTATGATAAAAT

Product: V-type ATP synthase subunit D

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MRLNVNPTRMELTKLKKRLATATRGHKLLKDKQDELMRRFIDLVKHNNELRKSVEEELQKSLKDFVMARALMSSEFLEEA
IVYPKESISLEIAKKNIMSVNVPIMKFKREMEEDEGSIYPYGYVNTSGELDTAIEKLYGILPKLLELAEVEKTCQLMADE
IEKTRRRVNALEYMTIPQLEETIKFIIMKLDENERGNLTRLMKVKSMMEEKK

Sequences:

>Translated_212_residues
MRLNVNPTRMELTKLKKRLATATRGHKLLKDKQDELMRRFIDLVKHNNELRKSVEEELQKSLKDFVMARALMSSEFLEEA
IVYPKESISLEIAKKNIMSVNVPIMKFKREMEEDEGSIYPYGYVNTSGELDTAIEKLYGILPKLLELAEVEKTCQLMADE
IEKTRRRVNALEYMTIPQLEETIKFIIMKLDENERGNLTRLMKVKSMMEEKK
>Mature_212_residues
MRLNVNPTRMELTKLKKRLATATRGHKLLKDKQDELMRRFIDLVKHNNELRKSVEEELQKSLKDFVMARALMSSEFLEEA
IVYPKESISLEIAKKNIMSVNVPIMKFKREMEEDEGSIYPYGYVNTSGELDTAIEKLYGILPKLLELAEVEKTCQLMADE
IEKTRRRVNALEYMTIPQLEETIKFIIMKLDENERGNLTRLMKVKSMMEEKK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family [H]

Homologues:

Organism=Homo sapiens, GI7706757, Length=207, Percent_Identity=29.4685990338164, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17553636, Length=213, Percent_Identity=31.4553990610329, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320784, Length=222, Percent_Identity=29.2792792792793, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20128937, Length=208, Percent_Identity=32.2115384615385, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355551, Length=207, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002699 [H]

Pfam domain/function: PF01813 ATP-synt_D [H]

EC number: 3.6.3.14

Molecular weight: Translated: 24893; Mature: 24893

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLNVNPTRMELTKLKKRLATATRGHKLLKDKQDELMRRFIDLVKHNNELRKSVEEELQK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
SLKDFVMARALMSSEFLEEAIVYPKESISLEIAKKNIMSVNVPIMKFKREMEEDEGSIYP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
YGYVNTSGELDTAIEKLYGILPKLLELAEVEKTCQLMADEIEKTRRRVNALEYMTIPQLE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ETIKFIIMKLDENERGNLTRLMKVKSMMEEKK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLNVNPTRMELTKLKKRLATATRGHKLLKDKQDELMRRFIDLVKHNNELRKSVEEELQK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
SLKDFVMARALMSSEFLEEAIVYPKESISLEIAKKNIMSVNVPIMKFKREMEEDEGSIYP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
YGYVNTSGELDTAIEKLYGILPKLLELAEVEKTCQLMADEIEKTRRRVNALEYMTIPQLE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ETIKFIIMKLDENERGNLTRLMKVKSMMEEKK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA