Click here to switch to the map view.

The map label for this gene is resE [H]

Identifier: 28210588

GI number: 28210588

Start: 926753

End: 928126

Strand: Direct

Name: resE [H]

Synonym: CTC00873

Alternate gene names: 28210588

Gene position: 926753-928126 (Clockwise)

Preceding gene: 28210587

Following gene: 28210589

Centisome position: 33.11

GC content: 23.94

Gene sequence:

>1374_bases
ATGCATAGCATAAGAAAAAAAATACTTATATCAATCTTAATATGTTCTATATTTGGACTTATTATATCCTTTGCACTTAT
AAATTTAAATGTAAATAAGAGTTTTAATAATTATATGGAGGATATGCAAAATAAAAGAGATAAAAGAATAATAGAATATT
TTTCTCAAGTTTATAAAAGAGATGGAAACTGGACAGAAGAGTCAGGTGAAGAATTAATTCATGAAGCGTATATGAATAAT
TATTGTTTATCTCTTATGAATACTGATAAGAAGATCGTATGGATGATGAATCCGGATAGAATAAAACAAAAGGGCCATAT
GATGAATATGATGCAAAATAAAAACAAAGGTATTTATACTAGTAAAACTTACAAGATAAAGACAGGAGAAAAAATTGTAG
GATATGTAGCTATTGGACAATATAGTTCTATATTGTTGTCAGAAGAGGATGAGCGATTTATAAATAGTTTAAATAATAGT
ATATTAATATCCATATTATTTACTATTGTTATTACAATTATTATAAGTCTATATATATCAAAACAAATATCTAATCCTAT
AAAAAAAGTATCAGATATTTCTGTAGCCCTTTCTAAAGGATATTATGGTATAGGAGTAGAAAGTAAAAGTAATATACTAG
AAATAAAAAACTTACAAGATAGCATAAATGAATTAAAAGAAAAATTAGAAAAACAGGATTCTTTAAGAAAAAGATTGGTA
TCAGATATCTCTCATGAAATAAGGACTCCTTTAAATATATTGCAAAATAATTTAGAAGCTATGATTGATGGAATATTTCC
TATAGATGAGGAAAGTTTAATAGGGTTAAATGAAGAAGTAATAAGATTTGGAAAATTATTAGATAACTTAAATATATTAA
AAGAAATCGAAGGTGAAGATATTAGTCTGAGTATGGATAAAGTATCTTTGAAAGATATATTAGAGGGAGTTATAAAAGAT
TTTTCAATTATAGCTAAAGATAAGCATATATTTTTTGAAAAAGATATAAATGAAGATAAAAATTATTATATATGTGGAGA
TGAAAATGCATTAAAGCAGGTTTTTATAAATATAATATCTAATTCTATAAAATTTACTGAAAATGGAGGAGATATTAAAG
TAGTTTTAAAAGAATTTAGAAACAATATAGAAACTATAATTGAGGATAATGGACAAGGGATAAAAAAAGAAGATTTACCC
TTTATATTTGAAAGGTTATATAGAGGAGATAAAAGTAGACATGAAATAGATGGAAGTGGTATAGGATTAACAATAGTAAA
AAGAATATTGAATATTCATTCCGCTTATATAGACGTAGAAAGTAAGTTAGATAAGGGTACAACAGTTAGAATAAAGTTTA
AAAAATATAAATAG

Upstream 100 bases:

>100_bases
ATGTAAAAAATATAAGAAAGAAAATAGAAAAGGATAGTAGAAATCCTAAGTACGTATTAACAGTTACTAGAGTTGGATAT
AAATTTGGTGGTGAAAGTTA

Downstream 100 bases:

>100_bases
ATTCATAAGCTTCAGTGTAGTAAATATACTTAGAGCTTATGAATTATTATTTAGTTATAGTAGAGATAGATATTAAGTTA
AACTTGAAATTTGCACTAAA

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MHSIRKKILISILICSIFGLIISFALINLNVNKSFNNYMEDMQNKRDKRIIEYFSQVYKRDGNWTEESGEELIHEAYMNN
YCLSLMNTDKKIVWMMNPDRIKQKGHMMNMMQNKNKGIYTSKTYKIKTGEKIVGYVAIGQYSSILLSEEDERFINSLNNS
ILISILFTIVITIIISLYISKQISNPIKKVSDISVALSKGYYGIGVESKSNILEIKNLQDSINELKEKLEKQDSLRKRLV
SDISHEIRTPLNILQNNLEAMIDGIFPIDEESLIGLNEEVIRFGKLLDNLNILKEIEGEDISLSMDKVSLKDILEGVIKD
FSIIAKDKHIFFEKDINEDKNYYICGDENALKQVFINIISNSIKFTENGGDIKVVLKEFRNNIETIIEDNGQGIKKEDLP
FIFERLYRGDKSRHEIDGSGIGLTIVKRILNIHSAYIDVESKLDKGTTVRIKFKKYK

Sequences:

>Translated_457_residues
MHSIRKKILISILICSIFGLIISFALINLNVNKSFNNYMEDMQNKRDKRIIEYFSQVYKRDGNWTEESGEELIHEAYMNN
YCLSLMNTDKKIVWMMNPDRIKQKGHMMNMMQNKNKGIYTSKTYKIKTGEKIVGYVAIGQYSSILLSEEDERFINSLNNS
ILISILFTIVITIIISLYISKQISNPIKKVSDISVALSKGYYGIGVESKSNILEIKNLQDSINELKEKLEKQDSLRKRLV
SDISHEIRTPLNILQNNLEAMIDGIFPIDEESLIGLNEEVIRFGKLLDNLNILKEIEGEDISLSMDKVSLKDILEGVIKD
FSIIAKDKHIFFEKDINEDKNYYICGDENALKQVFINIISNSIKFTENGGDIKVVLKEFRNNIETIIEDNGQGIKKEDLP
FIFERLYRGDKSRHEIDGSGIGLTIVKRILNIHSAYIDVESKLDKGTTVRIKFKKYK
>Mature_457_residues
MHSIRKKILISILICSIFGLIISFALINLNVNKSFNNYMEDMQNKRDKRIIEYFSQVYKRDGNWTEESGEELIHEAYMNN
YCLSLMNTDKKIVWMMNPDRIKQKGHMMNMMQNKNKGIYTSKTYKIKTGEKIVGYVAIGQYSSILLSEEDERFINSLNNS
ILISILFTIVITIIISLYISKQISNPIKKVSDISVALSKGYYGIGVESKSNILEIKNLQDSINELKEKLEKQDSLRKRLV
SDISHEIRTPLNILQNNLEAMIDGIFPIDEESLIGLNEEVIRFGKLLDNLNILKEIEGEDISLSMDKVSLKDILEGVIKD
FSIIAKDKHIFFEKDINEDKNYYICGDENALKQVFINIISNSIKFTENGGDIKVVLKEFRNNIETIIEDNGQGIKKEDLP
FIFERLYRGDKSRHEIDGSGIGLTIVKRILNIHSAYIDVESKLDKGTTVRIKFKKYK

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=32.3008849557522, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=29.2490118577075, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786783, Length=360, Percent_Identity=26.1111111111111, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788279, Length=277, Percent_Identity=26.3537906137184, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1789149, Length=375, Percent_Identity=24, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790346, Length=309, Percent_Identity=23.9482200647249, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1789403, Length=281, Percent_Identity=26.6903914590747, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788713, Length=257, Percent_Identity=26.8482490272374, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=23.3333333333333, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081816, Length=272, Percent_Identity=23.5294117647059, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082128, Length=276, Percent_Identity=25, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI48994928, Length=252, Percent_Identity=25.7936507936508, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=210, Percent_Identity=25.2380952380952, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786912, Length=258, Percent_Identity=21.7054263565891, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52658; Mature: 52658

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSIRKKILISILICSIFGLIISFALINLNVNKSFNNYMEDMQNKRDKRIIEYFSQVYKR
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHC
DGNWTEESGEELIHEAYMNNYCLSLMNTDKKIVWMMNPDRIKQKGHMMNMMQNKNKGIYT
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCEEE
SKTYKIKTGEKIVGYVAIGQYSSILLSEEDERFINSLNNSILISILFTIVITIIISLYIS
CCEEEEECCCEEEEEEEECCHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
KQISNPIKKVSDISVALSKGYYGIGVESKSNILEIKNLQDSINELKEKLEKQDSLRKRLV
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDISHEIRTPLNILQNNLEAMIDGIFPIDEESLIGLNEEVIRFGKLLDNLNILKEIEGED
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
ISLSMDKVSLKDILEGVIKDFSIIAKDKHIFFEKDINEDKNYYICGDENALKQVFINIIS
EEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHHHH
NSIKFTENGGDIKVVLKEFRNNIETIIEDNGQGIKKEDLPFIFERLYRGDKSRHEIDGSG
CCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
IGLTIVKRILNIHSAYIDVESKLDKGTTVRIKFKKYK
CHHHHHHHHHHHHHHHEEHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure
MHSIRKKILISILICSIFGLIISFALINLNVNKSFNNYMEDMQNKRDKRIIEYFSQVYKR
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHC
DGNWTEESGEELIHEAYMNNYCLSLMNTDKKIVWMMNPDRIKQKGHMMNMMQNKNKGIYT
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCEEE
SKTYKIKTGEKIVGYVAIGQYSSILLSEEDERFINSLNNSILISILFTIVITIIISLYIS
CCEEEEECCCEEEEEEEECCHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
KQISNPIKKVSDISVALSKGYYGIGVESKSNILEIKNLQDSINELKEKLEKQDSLRKRLV
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDISHEIRTPLNILQNNLEAMIDGIFPIDEESLIGLNEEVIRFGKLLDNLNILKEIEGED
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
ISLSMDKVSLKDILEGVIKDFSIIAKDKHIFFEKDINEDKNYYICGDENALKQVFINIIS
EEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHHHH
NSIKFTENGGDIKVVLKEFRNNIETIIEDNGQGIKKEDLPFIFERLYRGDKSRHEIDGSG
CCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
IGLTIVKRILNIHSAYIDVESKLDKGTTVRIKFKKYK
CHHHHHHHHHHHHHHHEEHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]