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The map label for this gene is yhdH [H]

Identifier: 28210536

GI number: 28210536

Start: 867380

End: 868759

Strand: Direct

Name: yhdH [H]

Synonym: CTC00819

Alternate gene names: 28210536

Gene position: 867380-868759 (Clockwise)

Preceding gene: 28210535

Following gene: 28210537

Centisome position: 30.99

GC content: 35.14

Gene sequence:

>1380_bases
ATGACTCCTATTATAAGGTTAAAAGTGGGGAGGAAATATATGAAAACTGAAGTTACTCAAAATACTCAAAAAGTTGCTAA
GTTTGAATCCAAATGGGGATTTGTATTAGCATGTGTAGGTTCTGCCGTAGGTATGGCCAATGTCTGGGGATTCCCTTACA
AATTAGGTAGCAACGGTGGTGGAGCATTTTTAGTAGCTTATATTATATTTATAGTTCTTTTTAGTTATGTAGGACTTTCT
GCAGAATATGCAATTGGTCGTAGGGCAAAGACTGGAACACTTGGTGCCTACGAAAATGCTTGGAGGTCAGGTGGTAAAGA
AGGCATTGGAAAAGTTGTGGGTTGGCTTCCTCTTGCAGGTTCTATGTGTATAGCAATAGGATATGCAGTAATTATTTCTT
ATGTATTAAAAGGATGGAGTCAATCTGTTACAGGTACCCTTATGACGGTTGATACAGGTGCATGGTTTGAGTCCTTTGCT
ATGACAGACTATTCAGTTGTTCCATATCATTTAATAGTTGTTGTTGGAACATTGCTGACATTGACACTTGGTGCAGATAG
TATTGAGAAGTCTAATAAAATTATGATGCCATTGTTTTTTATATTATTTGTAATTCTTGCTATTCGTGTAGCTTTATTAC
CAGGGGCAGTAGAAGGATATAAATTTATGTTTATGCCAAGATGGGAAGCCTTGAAAGATCCTATGGTCTGGGTTTGGGCA
ATGGGTCAAGCCTTTTTCTCCTTATCTGTAACTGGTAGTGGTATGATTGTATATGGTGCATATCTATCAGACAGTGAAGA
TATTGTAGATGGAGCAAAAAATACTGCCATATTTGACTTAATTGCAGCAATGGTTGCAGCATTAGTTATTATACCTGCTT
GTTTTGCATATAATGTAGACGTTGGATCAGGCCCAGGACTTCTTTTTGTAACCTTACCCAAAATACTACAAGATATACCA
GGAGGCAGAGTATTTGCAATAATATTATTTACAGCAGTAGTATTTGGTGGGGTATCCTCTCTACAAAACATGTTTGAAGT
AGTTGGAGAATCATTAATGTATAAATTCCCTAAATTAAAACGTATTCCTATGCTAATATTACTTTGTATAATTTGTTTTG
GTATAGGTGTTAATATGGAACCTATATTTAAATGGGGACCATGGATGGATCTTATATCTATATATATTATTCCAATTGGA
GCAACTTTAGGTGCTATATCTTGGTTCTGGATTATGAAAAAAGAAGATCTACTTGATGAAATCAACTTAGGAGCCAAAAA
GAAACAAGGAGACTTATGGTATAATCTAGGCAAATATCTTTATGTACCCTTTGCAACACTTTTATGTTTAGTTGCTCTAT
TTATGAAAGTATCATTTTAA

Upstream 100 bases:

>100_bases
AAAAATTTATTATTCTATATTTCCAGGCACAATGCCTGGAAATATAGAATATATATTATAAAGAAATATAACTGATCAGA
AATAAGAATACTACTTTATA

Downstream 100 bases:

>100_bases
GGTTTAATAAATATTTTAAGGAGGTTGTGGTGAATTATCGCTCAACCTCTTTTGTTTACATAATAAAAAATTAATGGTAT
AATATATCAAATTAATTTAT

Product: sodium- and chloride-dependent transporter, putative tyrosine transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MTPIIRLKVGRKYMKTEVTQNTQKVAKFESKWGFVLACVGSAVGMANVWGFPYKLGSNGGGAFLVAYIIFIVLFSYVGLS
AEYAIGRRAKTGTLGAYENAWRSGGKEGIGKVVGWLPLAGSMCIAIGYAVIISYVLKGWSQSVTGTLMTVDTGAWFESFA
MTDYSVVPYHLIVVVGTLLTLTLGADSIEKSNKIMMPLFFILFVILAIRVALLPGAVEGYKFMFMPRWEALKDPMVWVWA
MGQAFFSLSVTGSGMIVYGAYLSDSEDIVDGAKNTAIFDLIAAMVAALVIIPACFAYNVDVGSGPGLLFVTLPKILQDIP
GGRVFAIILFTAVVFGGVSSLQNMFEVVGESLMYKFPKLKRIPMLILLCIICFGIGVNMEPIFKWGPWMDLISIYIIPIG
ATLGAISWFWIMKKEDLLDEINLGAKKKQGDLWYNLGKYLYVPFATLLCLVALFMKVSF

Sequences:

>Translated_459_residues
MTPIIRLKVGRKYMKTEVTQNTQKVAKFESKWGFVLACVGSAVGMANVWGFPYKLGSNGGGAFLVAYIIFIVLFSYVGLS
AEYAIGRRAKTGTLGAYENAWRSGGKEGIGKVVGWLPLAGSMCIAIGYAVIISYVLKGWSQSVTGTLMTVDTGAWFESFA
MTDYSVVPYHLIVVVGTLLTLTLGADSIEKSNKIMMPLFFILFVILAIRVALLPGAVEGYKFMFMPRWEALKDPMVWVWA
MGQAFFSLSVTGSGMIVYGAYLSDSEDIVDGAKNTAIFDLIAAMVAALVIIPACFAYNVDVGSGPGLLFVTLPKILQDIP
GGRVFAIILFTAVVFGGVSSLQNMFEVVGESLMYKFPKLKRIPMLILLCIICFGIGVNMEPIFKWGPWMDLISIYIIPIG
ATLGAISWFWIMKKEDLLDEINLGAKKKQGDLWYNLGKYLYVPFATLLCLVALFMKVSF
>Mature_458_residues
TPIIRLKVGRKYMKTEVTQNTQKVAKFESKWGFVLACVGSAVGMANVWGFPYKLGSNGGGAFLVAYIIFIVLFSYVGLSA
EYAIGRRAKTGTLGAYENAWRSGGKEGIGKVVGWLPLAGSMCIAIGYAVIISYVLKGWSQSVTGTLMTVDTGAWFESFAM
TDYSVVPYHLIVVVGTLLTLTLGADSIEKSNKIMMPLFFILFVILAIRVALLPGAVEGYKFMFMPRWEALKDPMVWVWAM
GQAFFSLSVTGSGMIVYGAYLSDSEDIVDGAKNTAIFDLIAAMVAALVIIPACFAYNVDVGSGPGLLFVTLPKILQDIPG
GRVFAIILFTAVVFGGVSSLQNMFEVVGESLMYKFPKLKRIPMLILLCIICFGIGVNMEPIFKWGPWMDLISIYIIPIGA
TLGAISWFWIMKKEDLLDEINLGAKKKQGDLWYNLGKYLYVPFATLLCLVALFMKVSF

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=430, Percent_Identity=26.7441860465116, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI51468073, Length=308, Percent_Identity=25.974025974026, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4507043, Length=403, Percent_Identity=24.317617866005, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI194018524, Length=298, Percent_Identity=26.510067114094, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI7657587, Length=426, Percent_Identity=24.8826291079812, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI33354281, Length=318, Percent_Identity=25.4716981132075, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI58219014, Length=319, Percent_Identity=26.9592476489028, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4507041, Length=428, Percent_Identity=24.0654205607477, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI134304856, Length=397, Percent_Identity=23.1738035264484, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI171184408, Length=419, Percent_Identity=23.3890214797136, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI171184406, Length=419, Percent_Identity=23.3890214797136, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI171184404, Length=419, Percent_Identity=23.3890214797136, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI92859670, Length=193, Percent_Identity=31.0880829015544, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17554804, Length=484, Percent_Identity=22.7272727272727, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI115534083, Length=485, Percent_Identity=20.2061855670103, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17136952, Length=392, Percent_Identity=26.2755102040816, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281364394, Length=392, Percent_Identity=26.2755102040816, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28574704, Length=392, Percent_Identity=26.2755102040816, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136950, Length=392, Percent_Identity=26.2755102040816, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28574702, Length=392, Percent_Identity=26.2755102040816, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24639514, Length=416, Percent_Identity=28.125, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI221329674, Length=416, Percent_Identity=28.125, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24639516, Length=436, Percent_Identity=27.0642201834862, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281365034, Length=419, Percent_Identity=23.1503579952267, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24762620, Length=409, Percent_Identity=25.6723716381418, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24661428, Length=414, Percent_Identity=23.6714975845411, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19921936, Length=422, Percent_Identity=21.3270142180095, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281363702, Length=387, Percent_Identity=23.2558139534884, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24582567, Length=432, Percent_Identity=25.6944444444444, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI45551088, Length=397, Percent_Identity=24.6851385390428, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24652942, Length=397, Percent_Identity=24.6851385390428, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24655079, Length=448, Percent_Identity=22.0982142857143, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281363700, Length=360, Percent_Identity=23.6111111111111, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281364136, Length=183, Percent_Identity=28.9617486338798, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921352, Length=206, Percent_Identity=24.2718446601942, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584353, Length=206, Percent_Identity=24.2718446601942, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551183, Length=181, Percent_Identity=27.6243093922652, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45550877, Length=181, Percent_Identity=27.6243093922652, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24654186, Length=170, Percent_Identity=28.8235294117647, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 50291; Mature: 50159

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPIIRLKVGRKYMKTEVTQNTQKVAKFESKWGFVLACVGSAVGMANVWGFPYKLGSNGG
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHCCCCEEECCCCC
GAFLVAYIIFIVLFSYVGLSAEYAIGRRAKTGTLGAYENAWRSGGKEGIGKVVGWLPLAG
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
SMCIAIGYAVIISYVLKGWSQSVTGTLMTVDTGAWFESFAMTDYSVVPYHLIVVVGTLLT
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHH
LTLGADSIEKSNKIMMPLFFILFVILAIRVALLPGAVEGYKFMFMPRWEALKDPMVWVWA
HHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHCCCEEEEEE
MGQAFFSLSVTGSGMIVYGAYLSDSEDIVDGAKNTAIFDLIAAMVAALVIIPACFAYNVD
HHHHHEEEEECCCCEEEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEECC
VGSGPGLLFVTLPKILQDIPGGRVFAIILFTAVVFGGVSSLQNMFEVVGESLMYKFPKLK
CCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCC
RIPMLILLCIICFGIGVNMEPIFKWGPWMDLISIYIIPIGATLGAISWFWIMKKEDLLDE
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHH
INLGAKKKQGDLWYNLGKYLYVPFATLLCLVALFMKVSF
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPIIRLKVGRKYMKTEVTQNTQKVAKFESKWGFVLACVGSAVGMANVWGFPYKLGSNGG
CCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHCCCCEEECCCCC
GAFLVAYIIFIVLFSYVGLSAEYAIGRRAKTGTLGAYENAWRSGGKEGIGKVVGWLPLAG
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
SMCIAIGYAVIISYVLKGWSQSVTGTLMTVDTGAWFESFAMTDYSVVPYHLIVVVGTLLT
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHH
LTLGADSIEKSNKIMMPLFFILFVILAIRVALLPGAVEGYKFMFMPRWEALKDPMVWVWA
HHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHCCCEEEEEE
MGQAFFSLSVTGSGMIVYGAYLSDSEDIVDGAKNTAIFDLIAAMVAALVIIPACFAYNVD
HHHHHEEEEECCCCEEEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEECC
VGSGPGLLFVTLPKILQDIPGGRVFAIILFTAVVFGGVSSLQNMFEVVGESLMYKFPKLK
CCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCC
RIPMLILLCIICFGIGVNMEPIFKWGPWMDLISIYIIPIGATLGAISWFWIMKKEDLLDE
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHH
INLGAKKKQGDLWYNLGKYLYVPFATLLCLVALFMKVSF
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]