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The map label for this gene is ifcA [H]

Identifier: 28210528

GI number: 28210528

Start: 857316

End: 859070

Strand: Direct

Name: ifcA [H]

Synonym: CTC00811

Alternate gene names: 28210528

Gene position: 857316-859070 (Clockwise)

Preceding gene: 28210527

Following gene: 28210529

Centisome position: 30.63

GC content: 32.36

Gene sequence:

>1755_bases
ATGAAATTTAAATTTAAAAAGACATTAGTTTTTTTTATGTTACTTATTTTTTCCTTTAGTATTTTAGGATGCAGTAAGGG
TACTTCAGGTTCAGAGAAAAAATTTAAAGCAGGCAAATATACAGCTGAAGCAAAAGGACATAATGCTCCACTAAAAGTAG
AAGTAGAAGTGGACGACTCATCAATTAAGGAAATAAAAATATTGGAACACAAAGAAACGCCGGGTATAAGTGATGCTGCA
TTAAAAGATATACCTAAAGGTATAGTAGAAGCACAAACCCTTGCGGTAGACACTATTTCAGGAGCTACTATAACAAGTAA
TGCAGTTATAGTAGCTATTACTGAAGCTTTAAAACAGGCAGGTGGAAATATAGATGAATTAAAGAAAAAAAGCAAAGATG
AAGATGTAAAAAAAGAACAGGTTACTAAAGAAACCGATGTTATAGTTGTTGGAGCAGGTGGAGCTGGTATGTCAGCAGCG
GTAGCAGCAGCTGAAAAAGGAGCTAAAGTAATAGTTCTTGAAAAAATGCCCATGATTGGTGGAAACACCATAAGATCAGG
AGGAGCTTATAATGCTGTAGATGTTGAAAGACAAAAGGCTCAAGGAATAGAAGACTCTATAGATAAACATTATACTCAAA
CCTATGAAGGTGGAGACAAAAAAGGAGAATCCAAATTAGTAAAAATTCTTGTGGAAAATTCATTAGAGGGTAAGAAGTGG
TTAGAATCCTATGATATGAAGTTTAATGATAAAATAGGATCTGTTGTAGGATCATTATGGCCAAGAACTCATCAAGCCTC
TGACCCAGCTGGAATAGGATATATGAATGCTTTAAAAAAAGCGGCAGATAAACATAAAGTTGAAATACTGTTAAATACAA
AAGCTACAGAATTAATAATGAATAATGGAAAAGTTGTAGGGGTTAAAGCAGAAGGAGAAAAGAATTTATACGAAATAAAG
AGTAAAAAAGCTGTTGTAATGGCATCTGGAGGATTTGCAGCTAATGTGGAGATGAGAACAAAATATGTTCCAAACTTAAC
TAAAGATATGAAAACCACAAATCACCCTGGAGCAACAGGAGATGGAATAGTTATGGGAGAAAAGGTAGGAGCAGATTTAG
TTGGAATGGAATATATTCAACTTCTTCCTATGGCTATAGAGCTTACGGGACCTACAATAAATGTTGAAAATTCAATATTT
ATAAATAAAGAAGGAAATAGATTTATAAATGAAGATAATAGAAGAGATAAATTATGTGAAGCTATATTAAAACAAAAAGA
CGGTCAATATTATATGATAAATGATTCTCAAATTGTAAAAGAAACTAATGAATTAGGAGATAAAATTTCTGAATTAATAG
AAAAAGGAGTAGTTAAAAAAGCAGATAATTTAGATGAACTTGCAAAAGCGATAGGAGTACCTGTTGAAAATTTAAAAAAA
TCAGTAGAAGAATTTAATAAAGCAGTAGATAAAAAGAGTGATGCTTTTGGAAGAGGAGTATGGAAAAATAAAATAGAAAA
AGGACCTTTTTATGCTACACTAAGATATCCAGCAGTACATCATACTATGGGTGGATTAAAAATAAATGAAAAAACCCAAG
TTTTAGATAAATCAGGAAAAGTAATCCCAGGATTCTATGCAGCAGGAGAAATTACTGGTGGTATACATGGTGGAAATAGA
TTAGGTGGAAACGCATTACCAGATACAATTGTTTTTGGTAAAATAGCAGGGGAAAATGCAGCCAACGAAAAATAA

Upstream 100 bases:

>100_bases
CTAAATTTTGAGAAAAATTTAACAATTATATTGAAACAAGTCACCACATTTGTTAATATAATCTTAGATATGGGTAAAAT
TTTAAAGGGGGATAAATTTT

Downstream 100 bases:

>100_bases
TTTAATTAATATACTATAAAAGCCCTTATTTGAGGGCTTTTATAGTATATTAAGGAGATGATTGAGAATATGAAAGAAGA
ATTCTTTTTTTACAGCAAAG

Product: fumarate reductase flavoprotein subunit precursor

Products: NA

Alternate protein names: Fe(3+)-induced flavocytochrome C3; Ifc3; Iron(III)-induced flavocytochrome C3 [H]

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MKFKFKKTLVFFMLLIFSFSILGCSKGTSGSEKKFKAGKYTAEAKGHNAPLKVEVEVDDSSIKEIKILEHKETPGISDAA
LKDIPKGIVEAQTLAVDTISGATITSNAVIVAITEALKQAGGNIDELKKKSKDEDVKKEQVTKETDVIVVGAGGAGMSAA
VAAAEKGAKVIVLEKMPMIGGNTIRSGGAYNAVDVERQKAQGIEDSIDKHYTQTYEGGDKKGESKLVKILVENSLEGKKW
LESYDMKFNDKIGSVVGSLWPRTHQASDPAGIGYMNALKKAADKHKVEILLNTKATELIMNNGKVVGVKAEGEKNLYEIK
SKKAVVMASGGFAANVEMRTKYVPNLTKDMKTTNHPGATGDGIVMGEKVGADLVGMEYIQLLPMAIELTGPTINVENSIF
INKEGNRFINEDNRRDKLCEAILKQKDGQYYMINDSQIVKETNELGDKISELIEKGVVKKADNLDELAKAIGVPVENLKK
SVEEFNKAVDKKSDAFGRGVWKNKIEKGPFYATLRYPAVHHTMGGLKINEKTQVLDKSGKVIPGFYAAGEITGGIHGGNR
LGGNALPDTIVFGKIAGENAANEK

Sequences:

>Translated_584_residues
MKFKFKKTLVFFMLLIFSFSILGCSKGTSGSEKKFKAGKYTAEAKGHNAPLKVEVEVDDSSIKEIKILEHKETPGISDAA
LKDIPKGIVEAQTLAVDTISGATITSNAVIVAITEALKQAGGNIDELKKKSKDEDVKKEQVTKETDVIVVGAGGAGMSAA
VAAAEKGAKVIVLEKMPMIGGNTIRSGGAYNAVDVERQKAQGIEDSIDKHYTQTYEGGDKKGESKLVKILVENSLEGKKW
LESYDMKFNDKIGSVVGSLWPRTHQASDPAGIGYMNALKKAADKHKVEILLNTKATELIMNNGKVVGVKAEGEKNLYEIK
SKKAVVMASGGFAANVEMRTKYVPNLTKDMKTTNHPGATGDGIVMGEKVGADLVGMEYIQLLPMAIELTGPTINVENSIF
INKEGNRFINEDNRRDKLCEAILKQKDGQYYMINDSQIVKETNELGDKISELIEKGVVKKADNLDELAKAIGVPVENLKK
SVEEFNKAVDKKSDAFGRGVWKNKIEKGPFYATLRYPAVHHTMGGLKINEKTQVLDKSGKVIPGFYAAGEITGGIHGGNR
LGGNALPDTIVFGKIAGENAANEK
>Mature_584_residues
MKFKFKKTLVFFMLLIFSFSILGCSKGTSGSEKKFKAGKYTAEAKGHNAPLKVEVEVDDSSIKEIKILEHKETPGISDAA
LKDIPKGIVEAQTLAVDTISGATITSNAVIVAITEALKQAGGNIDELKKKSKDEDVKKEQVTKETDVIVVGAGGAGMSAA
VAAAEKGAKVIVLEKMPMIGGNTIRSGGAYNAVDVERQKAQGIEDSIDKHYTQTYEGGDKKGESKLVKILVENSLEGKKW
LESYDMKFNDKIGSVVGSLWPRTHQASDPAGIGYMNALKKAADKHKVEILLNTKATELIMNNGKVVGVKAEGEKNLYEIK
SKKAVVMASGGFAANVEMRTKYVPNLTKDMKTTNHPGATGDGIVMGEKVGADLVGMEYIQLLPMAIELTGPTINVENSIF
INKEGNRFINEDNRRDKLCEAILKQKDGQYYMINDSQIVKETNELGDKISELIEKGVVKKADNLDELAKAIGVPVENLKK
SVEEFNKAVDKKSDAFGRGVWKNKIEKGPFYATLRYPAVHHTMGGLKINEKTQVLDKSGKVIPGFYAAGEITGGIHGGNR
LGGNALPDTIVFGKIAGENAANEK

Specific function: Catalyzes unidirectional fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=441, Percent_Identity=25.1700680272109, Blast_Score=91, Evalue=4e-18,
Organism=Escherichia coli, GI1788928, Length=464, Percent_Identity=26.5086206896552, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790597, Length=470, Percent_Identity=25.3191489361702, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786942, Length=479, Percent_Identity=24.2171189979123, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71986328, Length=470, Percent_Identity=33.1914893617021, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17505833, Length=449, Percent_Identity=25.1670378619154, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17550100, Length=473, Percent_Identity=26.6384778012685, Blast_Score=96, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320788, Length=473, Percent_Identity=31.5010570824524, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6322511, Length=479, Percent_Identity=29.6450939457203, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6322701, Length=518, Percent_Identity=25.6756756756757, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6322416, Length=506, Percent_Identity=26.4822134387352, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24663005, Length=484, Percent_Identity=24.3801652892562, Blast_Score=87, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 63070; Mature: 63070

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKFKKTLVFFMLLIFSFSILGCSKGTSGSEKKFKAGKYTAEAKGHNAPLKVEVEVDDS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEECCC
SIKEIKILEHKETPGISDAALKDIPKGIVEAQTLAVDTISGATITSNAVIVAITEALKQA
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCEEECCCEEEEEHHHHHHH
GGNIDELKKKSKDEDVKKEQVTKETDVIVVGAGGAGMSAAVAAAEKGAKVIVLEKMPMIG
CCCHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCC
GNTIRSGGAYNAVDVERQKAQGIEDSIDKHYTQTYEGGDKKGESKLVKILVENSLEGKKW
CCEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHH
LESYDMKFNDKIGSVVGSLWPRTHQASDPAGIGYMNALKKAADKHKVEILLNTKATELIM
HHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEE
NNGKVVGVKAEGEKNLYEIKSKKAVVMASGGFAANVEMRTKYVPNLTKDMKTTNHPGATG
CCCEEEEEEECCCCCHHHHCCCCEEEEECCCEEEEEEEEECCCCCHHHHHCCCCCCCCCC
DGIVMGEKVGADLVGMEYIQLLPMAIELTGPTINVENSIFINKEGNRFINEDNRRDKLCE
CCEEEEHHCCCCHHHHHHHHHCCEEEEECCCEEECCCEEEEECCCCCCCCCCCHHHHHHH
AILKQKDGQYYMINDSQIVKETNELGDKISELIEKGVVKKADNLDELAKAIGVPVENLKK
HHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHH
SVEEFNKAVDKKSDAFGRGVWKNKIEKGPFYATLRYPAVHHTMGGLKINEKTQVLDKSGK
HHHHHHHHHCCCCCHHHCCHHHHCCCCCCEEEEEECCHHHHCCCCEEECCHHHHHHCCCC
VIPGFYAAGEITGGIHGGNRLGGNALPDTIVFGKIAGENAANEK
CCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MKFKFKKTLVFFMLLIFSFSILGCSKGTSGSEKKFKAGKYTAEAKGHNAPLKVEVEVDDS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEECCC
SIKEIKILEHKETPGISDAALKDIPKGIVEAQTLAVDTISGATITSNAVIVAITEALKQA
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCEEECCCEEEEEHHHHHHH
GGNIDELKKKSKDEDVKKEQVTKETDVIVVGAGGAGMSAAVAAAEKGAKVIVLEKMPMIG
CCCHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCC
GNTIRSGGAYNAVDVERQKAQGIEDSIDKHYTQTYEGGDKKGESKLVKILVENSLEGKKW
CCEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHH
LESYDMKFNDKIGSVVGSLWPRTHQASDPAGIGYMNALKKAADKHKVEILLNTKATELIM
HHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEE
NNGKVVGVKAEGEKNLYEIKSKKAVVMASGGFAANVEMRTKYVPNLTKDMKTTNHPGATG
CCCEEEEEEECCCCCHHHHCCCCEEEEECCCEEEEEEEEECCCCCHHHHHCCCCCCCCCC
DGIVMGEKVGADLVGMEYIQLLPMAIELTGPTINVENSIFINKEGNRFINEDNRRDKLCE
CCEEEEHHCCCCHHHHHHHHHCCEEEEECCCEEECCCEEEEECCCCCCCCCCCHHHHHHH
AILKQKDGQYYMINDSQIVKETNELGDKISELIEKGVVKKADNLDELAKAIGVPVENLKK
HHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHH
SVEEFNKAVDKKSDAFGRGVWKNKIEKGPFYATLRYPAVHHTMGGLKINEKTQVLDKSGK
HHHHHHHHHCCCCCHHHCCHHHHCCCCCCEEEEEECCHHHHCCCCEEECCHHHHHHCCCC
VIPGFYAAGEITGGIHGGNRLGGNALPDTIVFGKIAGENAANEK
CCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10455032; 10581549 [H]