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The map label for this gene is cobO [H]

Identifier: 28210464

GI number: 28210464

Start: 768061

End: 768597

Strand: Direct

Name: cobO [H]

Synonym: CTC00744

Alternate gene names: 28210464

Gene position: 768061-768597 (Clockwise)

Preceding gene: 28210463

Following gene: 28210465

Centisome position: 27.44

GC content: 30.73

Gene sequence:

>537_bases
ATGAAAGAAGGGATTTATATGTCAAATAAAGGATATGTTCAAGTATATACTGGCAATGGTAAAGGTAAAACTACAGCGGC
TTTAGGTTTATCTCTAAGAGCTACTTGTGCTGGTAAAAAAGTATTTTTTGGGCAATTTACAAAGGGAATGAATTATAGTG
AGTTAAAGGCTCCAGAAATACTGCCTAACTTTACATTAGAACAGTTTGGAAGAAATGCTTTTATATTTGGAACACCTTCA
AAAGCTGACATAGAAGAAGCAAAAAAAGGTTTAAAAAGAGCAGAGGAAGTTTTAACATCAGGTGAATATGATGTTGTAGT
TTTCGATGAAATAAATATAGCGTTATTTTATGAATTATTCTCAGTTCAAGAGGTTCTAGATTTAATAGATAGAAAAGCAG
AACATACTGAGTTAATTTTAACAGGAAGATATGCACCACAAGAAATAATAGATAGAGCAGATTTAGTTACAGAAATGAGA
GAAATAAAACATTATTATACTCAAGGAGTTCCTTGTAGAAAAGGAATTGAAAACTAA

Upstream 100 bases:

>100_bases
TTTTGACTAGGGAAAATAGTATTAAAAGTATTTAGAAATAATAGATATAAGTATTTATTTATGTTATATTAAGAGTAAAT
ATATAAATAAATTTAAACAT

Downstream 100 bases:

>100_bases
TAATTAAAATAGAATAATATGAATAAAAAAGGTGAAATAGTTATTTCTTAAAAGGGAAGCATGGTGAAAATCCATCACGG
TCCCGCCACTGTAATCAGGG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MKEGIYMSNKGYVQVYTGNGKGKTTAALGLSLRATCAGKKVFFGQFTKGMNYSELKAPEILPNFTLEQFGRNAFIFGTPS
KADIEEAKKGLKRAEEVLTSGEYDVVVFDEINIALFYELFSVQEVLDLIDRKAEHTELILTGRYAPQEIIDRADLVTEMR
EIKHYYTQGVPCRKGIEN

Sequences:

>Translated_178_residues
MKEGIYMSNKGYVQVYTGNGKGKTTAALGLSLRATCAGKKVFFGQFTKGMNYSELKAPEILPNFTLEQFGRNAFIFGTPS
KADIEEAKKGLKRAEEVLTSGEYDVVVFDEINIALFYELFSVQEVLDLIDRKAEHTELILTGRYAPQEIIDRADLVTEMR
EIKHYYTQGVPCRKGIEN
>Mature_178_residues
MKEGIYMSNKGYVQVYTGNGKGKTTAALGLSLRATCAGKKVFFGQFTKGMNYSELKAPEILPNFTLEQFGRNAFIFGTPS
KADIEEAKKGLKRAEEVLTSGEYDVVVFDEINIALFYELFSVQEVLDLIDRKAEHTELILTGRYAPQEIIDRADLVTEMR
EIKHYYTQGVPCRKGIEN

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=169, Percent_Identity=31.9526627218935, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 20037; Mature: 20037

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEGIYMSNKGYVQVYTGNGKGKTTAALGLSLRATCAGKKVFFGQFTKGMNYSELKAPEI
CCCCEEECCCCEEEEEECCCCCCEEEEECCEEEEECCCCEEEEHHHHCCCCCCCCCCCCC
LPNFTLEQFGRNAFIFGTPSKADIEEAKKGLKRAEEVLTSGEYDVVVFDEINIALFYELF
CCCCCHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
SVQEVLDLIDRKAEHTELILTGRYAPQEIIDRADLVTEMREIKHYYTQGVPCRKGIEN
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKEGIYMSNKGYVQVYTGNGKGKTTAALGLSLRATCAGKKVFFGQFTKGMNYSELKAPEI
CCCCEEECCCCEEEEEECCCCCCEEEEECCEEEEECCCCEEEEHHHHCCCCCCCCCCCCC
LPNFTLEQFGRNAFIFGTPSKADIEEAKKGLKRAEEVLTSGEYDVVVFDEINIALFYELF
CCCCCHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
SVQEVLDLIDRKAEHTELILTGRYAPQEIIDRADLVTEMREIKHYYTQGVPCRKGIEN
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]