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The map label for this gene is cobU [H]

Identifier: 28210439

GI number: 28210439

Start: 743964

End: 744518

Strand: Direct

Name: cobU [H]

Synonym: CTC00718

Alternate gene names: 28210439

Gene position: 743964-744518 (Clockwise)

Preceding gene: 28210438

Following gene: 28210440

Centisome position: 26.58

GC content: 30.63

Gene sequence:

>555_bases
ATGAATTCAGGTAAAGTCGTATTAGTAACTGGAGGCTCTAGAAGTGGTAAAAGTTCTTTTGCTGAAGAACTTTTAAAAGA
TAAAGATGACGTTTTATACATAGCAACCTCCATAGTAACAGATGAAGAAATGGAGGATAGAGTAAAAAAACACAGGGAAA
GAAGAAATTCATCCTGGGAAACCTATGAAGGATATTTGAATTTAGATAAGGCGATAGAAAATAGTGACAAAAAATATATC
CTGTTAGATTGTATTACCATAATGACGACTAATATAATGTTTAAAGATGAAAAGGACCTAGAAAAGGTATCTATGGAGGA
AATAGATAAAATAACTGGAAACATAAAAAAAGAATTCGATAAATTAATAGCTAAAGTAAGAGAAGAAGATAAAACTATTA
TAATGGTTACTAATGAAGTGGGTCTTGGATTAGTTCCTTCCTATAAGATAGGAAGAATATTTAGGGACATTGCAGGATTT
GTAAATCAGCACATAGGTAAAAAAGCAGATGAAATTTATTTAGTTTGTTGCGGACAACCGATGAAAATAAAATAG

Upstream 100 bases:

>100_bases
TATCTTTGATAAAATATGAATATGGGAATTTATATTTAGAATTTAAAATTCCAGCAGGATTTTAAATGTAAAAAATAGTA
TTTAGGAGGAGTATAAGAAA

Downstream 100 bases:

>100_bases
GGAGATGACATTGTGAAATACATATATAATTTTTTATTAATGATACAATTTTTAACAAGAATTCCTGTAAAAAGGAGTTT
ACCCTGTGAAAAAGAGGATT

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNSGKVVLVTGGSRSGKSSFAEELLKDKDDVLYIATSIVTDEEMEDRVKKHRERRNSSWETYEGYLNLDKAIENSDKKYI
LLDCITIMTTNIMFKDEKDLEKVSMEEIDKITGNIKKEFDKLIAKVREEDKTIIMVTNEVGLGLVPSYKIGRIFRDIAGF
VNQHIGKKADEIYLVCCGQPMKIK

Sequences:

>Translated_184_residues
MNSGKVVLVTGGSRSGKSSFAEELLKDKDDVLYIATSIVTDEEMEDRVKKHRERRNSSWETYEGYLNLDKAIENSDKKYI
LLDCITIMTTNIMFKDEKDLEKVSMEEIDKITGNIKKEFDKLIAKVREEDKTIIMVTNEVGLGLVPSYKIGRIFRDIAGF
VNQHIGKKADEIYLVCCGQPMKIK
>Mature_184_residues
MNSGKVVLVTGGSRSGKSSFAEELLKDKDDVLYIATSIVTDEEMEDRVKKHRERRNSSWETYEGYLNLDKAIENSDKKYI
LLDCITIMTTNIMFKDEKDLEKVSMEEIDKITGNIKKEFDKLIAKVREEDKTIIMVTNEVGLGLVPSYKIGRIFRDIAGF
VNQHIGKKADEIYLVCCGQPMKIK

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=186, Percent_Identity=41.9354838709677, Blast_Score=150, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21023; Mature: 21023

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSGKVVLVTGGSRSGKSSFAEELLKDKDDVLYIATSIVTDEEMEDRVKKHRERRNSSWE
CCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEHHHCCHHHHHHHHHHHHHCCCCCC
TYEGYLNLDKAIENSDKKYILLDCITIMTTNIMFKDEKDLEKVSMEEIDKITGNIKKEFD
HHHHHCCHHHHHCCCCCCEEHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHH
KLIAKVREEDKTIIMVTNEVGLGLVPSYKIGRIFRDIAGFVNQHIGKKADEIYLVCCGQP
HHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
MKIK
CCCC
>Mature Secondary Structure
MNSGKVVLVTGGSRSGKSSFAEELLKDKDDVLYIATSIVTDEEMEDRVKKHRERRNSSWE
CCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEHHHCCHHHHHHHHHHHHHCCCCCC
TYEGYLNLDKAIENSDKKYILLDCITIMTTNIMFKDEKDLEKVSMEEIDKITGNIKKEFD
HHHHHCCHHHHHCCCCCCEEHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHH
KLIAKVREEDKTIIMVTNEVGLGLVPSYKIGRIFRDIAGFVNQHIGKKADEIYLVCCGQP
HHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
MKIK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]