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The map label for this gene is yycG [H]

Identifier: 28210436

GI number: 28210436

Start: 740793

End: 741527

Strand: Direct

Name: yycG [H]

Synonym: CTC00715

Alternate gene names: 28210436

Gene position: 740793-741527 (Clockwise)

Preceding gene: 28210435

Following gene: 28210438

Centisome position: 26.46

GC content: 23.81

Gene sequence:

>735_bases
TTGAACTATACAGAAAAGATATTTCCTTTTACGAACATAGCTCATGATATAAAAACTCCTTTAAATATTATTAATAGTAG
TATTCAGCTTATTGAACTTAATTTAAAAGAAGGAAAAATAATAGATGAAAAACTTATTTTAAATGAACAAATAAAAATAT
TACAACAAAGTTCTAAAAAATTAATAAAATTAATAAATAATTTTATTGATAATACAAACATAAAAGATTTTAATGAAATG
AATATTGAATGCTGTAATATTGTTACTATAGTAGAAGAGAGTACATTATATTTTGCTGATTACTTAAAAAATAAGAACAT
AGAATTGATTTTTGATACTGATATAGAGGAAAAAGAAGTTGAATGTGACGTAGATAAAATAGAAAGTGTTATGTTCAATT
TGATTTCTAATGCTACAAAGTTTACTCCAGAATACGGTAAAGTATGGGTAAATATACTAGGTAAAACAAACTTCATAGAA
ATTGTTGTAAAAGATACAGGCATTGGAATACCTAAAGATAAGATAGATAGAGTTTTTCAAAAATCCATACGGTTAGACAA
CTCTTTTAATGAAATTGAAGGTAGCGGAATAGGATTATATATAGTTAAGACAATAGTAGATATGCATGGTGGAAAGATTA
TTGTAAATAGTGAAATTGGCAAAGGAAGTGAATTTATTATAAAAATACCTGCAAAAATTAAAAGAAAAGAAGGTTTAAAA
CAGAAAATTATGTGA

Upstream 100 bases:

>100_bases
ATGCAGTTTAATTTGTTTTAGAATGTAAAGAAGGTGATGAATTTATCATTAAACATTTTATTAGAAAAATAAAAATCTAT
ATAGGGGAGGGAAGAAAATA

Downstream 100 bases:

>100_bases
TAATATTTTTCAATGTAAAGATTTGAAATAGTTAGCTTTGTAAAAAAGTTAATTAAAAATTAACAAAGAAAAATGCAAAG
AAAAGGGTTACATAAATGCA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MNYTEKIFPFTNIAHDIKTPLNIINSSIQLIELNLKEGKIIDEKLILNEQIKILQQSSKKLIKLINNFIDNTNIKDFNEM
NIECCNIVTIVEESTLYFADYLKNKNIELIFDTDIEEKEVECDVDKIESVMFNLISNATKFTPEYGKVWVNILGKTNFIE
IVVKDTGIGIPKDKIDRVFQKSIRLDNSFNEIEGSGIGLYIVKTIVDMHGGKIIVNSEIGKGSEFIIKIPAKIKRKEGLK
QKIM

Sequences:

>Translated_244_residues
MNYTEKIFPFTNIAHDIKTPLNIINSSIQLIELNLKEGKIIDEKLILNEQIKILQQSSKKLIKLINNFIDNTNIKDFNEM
NIECCNIVTIVEESTLYFADYLKNKNIELIFDTDIEEKEVECDVDKIESVMFNLISNATKFTPEYGKVWVNILGKTNFIE
IVVKDTGIGIPKDKIDRVFQKSIRLDNSFNEIEGSGIGLYIVKTIVDMHGGKIIVNSEIGKGSEFIIKIPAKIKRKEGLK
QKIM
>Mature_244_residues
MNYTEKIFPFTNIAHDIKTPLNIINSSIQLIELNLKEGKIIDEKLILNEQIKILQQSSKKLIKLINNFIDNTNIKDFNEM
NIECCNIVTIVEESTLYFADYLKNKNIELIFDTDIEEKEVECDVDKIESVMFNLISNATKFTPEYGKVWVNILGKTNFIE
IVVKDTGIGIPKDKIDRVFQKSIRLDNSFNEIEGSGIGLYIVKTIVDMHGGKIIVNSEIGKGSEFIIKIPAKIKRKEGLK
QKIM

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=27.8761061946903, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=24.2290748898678, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=26.5560165975104, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=226, Percent_Identity=28.3185840707965, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=29.3103448275862, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=27.3913043478261, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788393, Length=223, Percent_Identity=20.627802690583, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=27.2340425531915, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788713, Length=233, Percent_Identity=25.7510729613734, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=24.6696035242291, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787374, Length=216, Percent_Identity=23.6111111111111, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=223, Percent_Identity=24.2152466367713, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 27919; Mature: 27919

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYTEKIFPFTNIAHDIKTPLNIINSSIQLIELNLKEGKIIDEKLILNEQIKILQQSSKK
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHH
LIKLINNFIDNTNIKDFNEMNIECCNIVTIVEESTLYFADYLKNKNIELIFDTDIEEKEV
HHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCHH
ECDVDKIESVMFNLISNATKFTPEYGKVWVNILGKTNFIEIVVKDTGIGIPKDKIDRVFQ
CCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHH
KSIRLDNSFNEIEGSGIGLYIVKTIVDMHGGKIIVNSEIGKGSEFIIKIPAKIKRKEGLK
HHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCHHHHHCCHH
QKIM
HHCC
>Mature Secondary Structure
MNYTEKIFPFTNIAHDIKTPLNIINSSIQLIELNLKEGKIIDEKLILNEQIKILQQSSKK
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHH
LIKLINNFIDNTNIKDFNEMNIECCNIVTIVEESTLYFADYLKNKNIELIFDTDIEEKEV
HHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCHH
ECDVDKIESVMFNLISNATKFTPEYGKVWVNILGKTNFIEIVVKDTGIGIPKDKIDRVFQ
CCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHH
KSIRLDNSFNEIEGSGIGLYIVKTIVDMHGGKIIVNSEIGKGSEFIIKIPAKIKRKEGLK
HHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCHHHHHCCHH
QKIM
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]