Click here to switch to the map view.

The map label for this gene is yqiR [H]

Identifier: 28210429

GI number: 28210429

Start: 728778

End: 730481

Strand: Direct

Name: yqiR [H]

Synonym: CTC00707

Alternate gene names: 28210429

Gene position: 728778-730481 (Clockwise)

Preceding gene: 28210428

Following gene: 28210430

Centisome position: 26.03

GC content: 28.64

Gene sequence:

>1704_bases
GTGTTTAGGAGGCGAGCGTTTATGTTTTCAAAAGTGAACAAATATTGTGATTACAGTATAAGGGTAGGTGCTATAATAAT
TAATAATCTAGGAGAAATCCAATTTATGAGTGATGAGTGTAGAAAAATACTATGTGCTAGAGAATATTCTTATAATCATA
TACAACAATTAATACCGTGCTTTAATATGAAAGATTTAATTAATAGTAGTACTAAAAGAAAAATAAAACTAAATAATAAA
AAATTAAATATGGAAGTAATATCATTAAAAGAAGAGTGTATGAAGGAGTTTCTAATTACATTAATTGATGCTAATGTCAT
AGATGTTATGTATGAAGAGCTTAAAGCTAAGGAAAAAAACTTAAAAATATTAAGCTTCATACTAGAATTAGCTTACGATG
GACTAGTAGTTATAGATAAGTATGGATATATAACTATGATAAACAAAACTTATGCTGATTTTTTAGGTGTAGATCAAGAA
AGATCTATAGGTAAGCATGTTACAGAGGTGATAGAAAGTACAAGAATGCATATAGTTGCTAAAACGGGAATAGCTGAAAC
AGCTCAGCTTCAAAAAGTTAAAGGAAAGTATATGATAGCCAATAGAATACCTGTAATAGAAAATGGAGAGCTAGTAGCGG
TAGCAGGTAAGGTTTTATTTAAAAATATAAAGGAATTAGATTTATTATATAAGAAAATAAGAAATATTGAAAATGAGTAT
AAAAAGTATAAAGGACAATTTGATGAAAGTAATAGTGCATCATACTCATTTGATAATATAATCGGAAAAAGTGACAAAAT
CAATAAAACCAAGGATTTAGCTAAGAAAGCAGCAAAGACAAATTCTAATGTATTGATAAGGGGAGAGAGTGGTACAGGAA
AGGAGCTTTTTGCACATGCTATACATATGGAAAGTGAAAGAGTATATGGAAACTTTATAAAATTAAATTGTGCAGCTATA
CCAAGAGATCTTTTGGAATCGGAGCTATTTGGTTATGAGGGAGGAGCTTTTACAGGGGCTAAGAAAGAGGGGAAGATAGG
GAAATTTGAATTAGCAGATGGAGGAACTATTTTTTTAGATGAAATAGGAGATATGCCTTTACATATGCAGGCTAAACTAT
TAAGAGTACTACAAGAAAGAGAAGTGGAAAGAATAGGGGCAACAAGAAGCAAAAAAATTGATGTGAGAGTAATTTCAGCA
ACTAATAGAGATTTAGAAAAGATGATAAAAGAAGGGGAATTCAGGGAAGATTTATATTATAGATTAAATGTAGTAACTGT
GAATATACCACCTTTAAGAGAAAGGAGAGAAGATATAAAGATTTTATCAGAGTATTTATTAGAAAAAATATCTAAAAAGC
TAGGTAAAAAAACAAAATCTTTTTCTAAAGAGGCTATGAGTTGTTTAATGAATTATAAATGGGAGGGAGGAGTAAGACAA
TTAGAAAACATAATAGAAAGAGCAGTTAATTTAGTTGAGCATAACGAAATGATTGAACCTAAACATTTTCCTGGAAATAT
AGTAAGTAATAAATATATAGTAGAAGATTCTGATTTAAATAAACTGATTAATCAAGTAGAAAAAGATATTATATTAGAAA
CACTAATTTATTGTAATTGGAATAAAACATTAGCAGCTAAGAAGCTGAATATAAGTAGAACCTCTTTGTATGAAAAGATA
GCTAAACATAATATAGCAATTTAG

Upstream 100 bases:

>100_bases
AAGGACAGGCTAAAGTAATGCCACCAAAGAAATGATATAATATAAAAAAACTATCTCATAATTTATGGGATAGTTTTTTT
GTATTAGATAAAACTAAAAA

Downstream 100 bases:

>100_bases
AAATTTCAATATATTGTAAAGATGTAAGGTAACAAGTACAAAAAAACAACATTAGAAAGTCAAATGTAAGGAAAACACTA
CATTTTTATCTGTTCAATTC

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MFRRRAFMFSKVNKYCDYSIRVGAIIINNLGEIQFMSDECRKILCAREYSYNHIQQLIPCFNMKDLINSSTKRKIKLNNK
KLNMEVISLKEECMKEFLITLIDANVIDVMYEELKAKEKNLKILSFILELAYDGLVVIDKYGYITMINKTYADFLGVDQE
RSIGKHVTEVIESTRMHIVAKTGIAETAQLQKVKGKYMIANRIPVIENGELVAVAGKVLFKNIKELDLLYKKIRNIENEY
KKYKGQFDESNSASYSFDNIIGKSDKINKTKDLAKKAAKTNSNVLIRGESGTGKELFAHAIHMESERVYGNFIKLNCAAI
PRDLLESELFGYEGGAFTGAKKEGKIGKFELADGGTIFLDEIGDMPLHMQAKLLRVLQEREVERIGATRSKKIDVRVISA
TNRDLEKMIKEGEFREDLYYRLNVVTVNIPPLRERREDIKILSEYLLEKISKKLGKKTKSFSKEAMSCLMNYKWEGGVRQ
LENIIERAVNLVEHNEMIEPKHFPGNIVSNKYIVEDSDLNKLINQVEKDIILETLIYCNWNKTLAAKKLNISRTSLYEKI
AKHNIAI

Sequences:

>Translated_567_residues
MFRRRAFMFSKVNKYCDYSIRVGAIIINNLGEIQFMSDECRKILCAREYSYNHIQQLIPCFNMKDLINSSTKRKIKLNNK
KLNMEVISLKEECMKEFLITLIDANVIDVMYEELKAKEKNLKILSFILELAYDGLVVIDKYGYITMINKTYADFLGVDQE
RSIGKHVTEVIESTRMHIVAKTGIAETAQLQKVKGKYMIANRIPVIENGELVAVAGKVLFKNIKELDLLYKKIRNIENEY
KKYKGQFDESNSASYSFDNIIGKSDKINKTKDLAKKAAKTNSNVLIRGESGTGKELFAHAIHMESERVYGNFIKLNCAAI
PRDLLESELFGYEGGAFTGAKKEGKIGKFELADGGTIFLDEIGDMPLHMQAKLLRVLQEREVERIGATRSKKIDVRVISA
TNRDLEKMIKEGEFREDLYYRLNVVTVNIPPLRERREDIKILSEYLLEKISKKLGKKTKSFSKEAMSCLMNYKWEGGVRQ
LENIIERAVNLVEHNEMIEPKHFPGNIVSNKYIVEDSDLNKLINQVEKDIILETLIYCNWNKTLAAKKLNISRTSLYEKI
AKHNIAI
>Mature_567_residues
MFRRRAFMFSKVNKYCDYSIRVGAIIINNLGEIQFMSDECRKILCAREYSYNHIQQLIPCFNMKDLINSSTKRKIKLNNK
KLNMEVISLKEECMKEFLITLIDANVIDVMYEELKAKEKNLKILSFILELAYDGLVVIDKYGYITMINKTYADFLGVDQE
RSIGKHVTEVIESTRMHIVAKTGIAETAQLQKVKGKYMIANRIPVIENGELVAVAGKVLFKNIKELDLLYKKIRNIENEY
KKYKGQFDESNSASYSFDNIIGKSDKINKTKDLAKKAAKTNSNVLIRGESGTGKELFAHAIHMESERVYGNFIKLNCAAI
PRDLLESELFGYEGGAFTGAKKEGKIGKFELADGGTIFLDEIGDMPLHMQAKLLRVLQEREVERIGATRSKKIDVRVISA
TNRDLEKMIKEGEFREDLYYRLNVVTVNIPPLRERREDIKILSEYLLEKISKKLGKKTKSFSKEAMSCLMNYKWEGGVRQ
LENIIERAVNLVEHNEMIEPKHFPGNIVSNKYIVEDSDLNKLINQVEKDIILETLIYCNWNKTLAAKKLNISRTSLYEKI
AKHNIAI

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=353, Percent_Identity=45.3257790368272, Blast_Score=283, Evalue=3e-77,
Organism=Escherichia coli, GI1790437, Length=315, Percent_Identity=45.3968253968254, Blast_Score=274, Evalue=1e-74,
Organism=Escherichia coli, GI1789233, Length=467, Percent_Identity=35.5460385438972, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI87082117, Length=355, Percent_Identity=40, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI1789087, Length=327, Percent_Identity=45.565749235474, Blast_Score=268, Evalue=8e-73,
Organism=Escherichia coli, GI1788905, Length=309, Percent_Identity=44.336569579288, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1790299, Length=327, Percent_Identity=40.3669724770642, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1786524, Length=320, Percent_Identity=39.0625, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI87082152, Length=316, Percent_Identity=39.873417721519, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI87081872, Length=321, Percent_Identity=37.6947040498442, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1787583, Length=317, Percent_Identity=37.2239747634069, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI87081858, Length=465, Percent_Identity=26.6666666666667, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1789828, Length=331, Percent_Identity=29.9093655589124, Blast_Score=143, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 65176; Mature: 65176

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRRRAFMFSKVNKYCDYSIRVGAIIINNLGEIQFMSDECRKILCAREYSYNHIQQLIPC
CCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECHHHHHHHHHHHHCCHHHHHHHHCC
FNMKDLINSSTKRKIKLNNKKLNMEVISLKEECMKEFLITLIDANVIDVMYEELKAKEKN
CCHHHHHCCCCCCEEEECCCEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
LKILSFILELAYDGLVVIDKYGYITMINKTYADFLGVDQERSIGKHVTEVIESTRMHIVA
HHHHHHHHHHHCCCEEEEECCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEE
KTGIAETAQLQKVKGKYMIANRIPVIENGELVAVAGKVLFKNIKELDLLYKKIRNIENEY
ECCCHHHHHHHHHCCCEEEECCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
KKYKGQFDESNSASYSFDNIIGKSDKINKTKDLAKKAAKTNSNVLIRGESGTGKELFAHA
HHHCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHH
IHMESERVYGNFIKLNCAAIPRDLLESELFGYEGGAFTGAKKEGKIGKFELADGGTIFLD
HHCCCHHHCCCEEEEEEHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEEE
EIGDMPLHMQAKLLRVLQEREVERIGATRSKKIDVRVISATNRDLEKMIKEGEFREDLYY
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHCCCCHHCEEE
RLNVVTVNIPPLRERREDIKILSEYLLEKISKKLGKKTKSFSKEAMSCLMNYKWEGGVRQ
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LENIIERAVNLVEHNEMIEPKHFPGNIVSNKYIVEDSDLNKLINQVEKDIILETLIYCNW
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
NKTLAAKKLNISRTSLYEKIAKHNIAI
CCHHHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFRRRAFMFSKVNKYCDYSIRVGAIIINNLGEIQFMSDECRKILCAREYSYNHIQQLIPC
CCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECHHHHHHHHHHHHCCHHHHHHHHCC
FNMKDLINSSTKRKIKLNNKKLNMEVISLKEECMKEFLITLIDANVIDVMYEELKAKEKN
CCHHHHHCCCCCCEEEECCCEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
LKILSFILELAYDGLVVIDKYGYITMINKTYADFLGVDQERSIGKHVTEVIESTRMHIVA
HHHHHHHHHHHCCCEEEEECCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEE
KTGIAETAQLQKVKGKYMIANRIPVIENGELVAVAGKVLFKNIKELDLLYKKIRNIENEY
ECCCHHHHHHHHHCCCEEEECCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
KKYKGQFDESNSASYSFDNIIGKSDKINKTKDLAKKAAKTNSNVLIRGESGTGKELFAHA
HHHCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHH
IHMESERVYGNFIKLNCAAIPRDLLESELFGYEGGAFTGAKKEGKIGKFELADGGTIFLD
HHCCCHHHCCCEEEEEEHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEEE
EIGDMPLHMQAKLLRVLQEREVERIGATRSKKIDVRVISATNRDLEKMIKEGEFREDLYY
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHCCCCHHCEEE
RLNVVTVNIPPLRERREDIKILSEYLLEKISKKLGKKTKSFSKEAMSCLMNYKWEGGVRQ
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LENIIERAVNLVEHNEMIEPKHFPGNIVSNKYIVEDSDLNKLINQVEKDIILETLIYCNW
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
NKTLAAKKLNISRTSLYEKIAKHNIAI
CCHHHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]