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The map label for this gene is uppP

Identifier: 28210284

GI number: 28210284

Start: 561864

End: 562679

Strand: Direct

Name: uppP

Synonym: CTC00545

Alternate gene names: 28210284

Gene position: 561864-562679 (Clockwise)

Preceding gene: 28210283

Following gene: 28210285

Centisome position: 20.07

GC content: 29.78

Gene sequence:

>816_bases
ATGCTTCTAATATTAAAAGCAATAATACTTGCAATAGTAGAAGGGCTAACAGAGTTTGTTCCTGTATCATCAACAGGACA
TTTAATACTTGTATCCGATGTTATTAATTTTAAAGGAGATTATGCAAATTTATTTAATGTAGTGATACAGTTAGGAGCTA
TATTAGCAGTAGTTGTGGTTTATTGGGACAAGCTACTCAACAGTGTAAAAGATATATTTGCACCAGACAGAAGAGGATTA
AGATTTTGGATAAACATAGTTGTAGCATGTATTCCAGCAGTTATATTTGGTTTTTCATTAGATGATTACATAGACAAGTA
TTTATTTAATCCAATAACAGTAGCAATTGGACTTGTAATTGGTGGTATACTTATGATTATTGTAGAAAATAAATACAGAC
GAAGAAGTAAAACTAAAAATATATATGATATGAAATTAAGACAATCTATATTTGTAGGAATGTTTCAGTGTTTAGCGCTA
TGGCCAGGAATGTCTAGATCAGCCTCTACTATTATGGGGGGATGGATAGCTGGGCTTTCACCAGTAGTTGCAGCAGAATT
TTCATTTTTCTTAGCTATACCAGTTATGGTAGGAGCATCAGGTTTAAAATTAGTGAAAAGTGGATTCTATATGACTAATA
TAGAATTTATAGCATTGATAGTAGGTTTTGTAGGAGCTTTTCTAGTATCCTTAGTAGTTATAGAAAAGTTTATAAAATTC
TTACAAAAAAAACCTATGAGAATATTTGCTATCTATAGAATATTTATAGGAGCTATACTATTAATATTAGCTATTTTTAA
AATAGTTACAATATAG

Upstream 100 bases:

>100_bases
TATAATAATTTTACTAATATCCATACTATAATCATGAAAAAAGTAGTATAATATATAGGATTGTTTTTAAAATTTATGTA
TAGAGAGCGAGAGTGATGGA

Downstream 100 bases:

>100_bases
TTTTGAAGAAGACTTATGTCTTCTTTTTTTATGCTCATTTTAAGGGGATTAATCATAGTATGTATTATGAAATTAAAACA
GAGGAGGTACTTATAATGGA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MLLILKAIILAIVEGLTEFVPVSSTGHLILVSDVINFKGDYANLFNVVIQLGAILAVVVVYWDKLLNSVKDIFAPDRRGL
RFWINIVVACIPAVIFGFSLDDYIDKYLFNPITVAIGLVIGGILMIIVENKYRRRSKTKNIYDMKLRQSIFVGMFQCLAL
WPGMSRSASTIMGGWIAGLSPVVAAEFSFFLAIPVMVGASGLKLVKSGFYMTNIEFIALIVGFVGAFLVSLVVIEKFIKF
LQKKPMRIFAIYRIFIGAILLILAIFKIVTI

Sequences:

>Translated_271_residues
MLLILKAIILAIVEGLTEFVPVSSTGHLILVSDVINFKGDYANLFNVVIQLGAILAVVVVYWDKLLNSVKDIFAPDRRGL
RFWINIVVACIPAVIFGFSLDDYIDKYLFNPITVAIGLVIGGILMIIVENKYRRRSKTKNIYDMKLRQSIFVGMFQCLAL
WPGMSRSASTIMGGWIAGLSPVVAAEFSFFLAIPVMVGASGLKLVKSGFYMTNIEFIALIVGFVGAFLVSLVVIEKFIKF
LQKKPMRIFAIYRIFIGAILLILAIFKIVTI
>Mature_271_residues
MLLILKAIILAIVEGLTEFVPVSSTGHLILVSDVINFKGDYANLFNVVIQLGAILAVVVVYWDKLLNSVKDIFAPDRRGL
RFWINIVVACIPAVIFGFSLDDYIDKYLFNPITVAIGLVIGGILMIIVENKYRRRSKTKNIYDMKLRQSIFVGMFQCLAL
WPGMSRSASTIMGGWIAGLSPVVAAEFSFFLAIPVMVGASGLKLVKSGFYMTNIEFIALIVGFVGAFLVSLVVIEKFIKF
LQKKPMRIFAIYRIFIGAILLILAIFKIVTI

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=264, Percent_Identity=45.0757575757576, Blast_Score=218, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_CLOTE (Q898B8)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781228.1
- ProteinModelPortal:   Q898B8
- GeneID:   1060197
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC00545
- NMPDR:   fig|212717.1.peg.450
- HOGENOM:   HBG391969
- OMA:   HDVIKTY
- PhylomeDB:   Q898B8
- ProtClustDB:   PRK00281
- BioCyc:   CTET212717:CTC_00545-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30113; Mature: 30113

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcd41244)-; HASH(0xcd133b8)-; HASH(0xb59b7f8)-; HASH(0x406facf0)-; HASH(0xbbcf434)-; HASH(0xd141b90)-; HASH(0xb4e2388)-; HASH(0xd141b48)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure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HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12552129