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The map label for this gene is mcp4 [H]

Identifier: 28210223

GI number: 28210223

Start: 478783

End: 480489

Strand: Direct

Name: mcp4 [H]

Synonym: CTC00474

Alternate gene names: 28210223

Gene position: 478783-480489 (Clockwise)

Preceding gene: 28210221

Following gene: 28210228

Centisome position: 17.1

GC content: 28.18

Gene sequence:

>1707_bases
GTGAAAAATTTGAATCTAAGCAAAAGACTTATCCTATCTTTTACTCTTTTAATTATAGTGATAATCACAAATGGTATTGT
TGGTATCAGATCTGTAAATAAAATGGATTTTAACGCTAATGAAATTGCAGGTTCTATGGATGCAATAAATAGAATTAGGC
ATATAGAGACCCATTTGATTGAATCTAAAGCAAGTACAATAATATTACTTAACGAAAAAGATGTAAATAAAATTAATAGA
TTAAAAGAAGAGTTAAACAGTTTAAGTGAAGAAACTAATGAAATAATAAGAGAATGTATTAATTCACAAGATAGTTGGTT
TAAAGGAGAGGCAGAAGTATTTAAGGAGTTTCAAAATAAACTAAAAGTATACAGGAGTACTAGAGATGATATATGTAATT
TAGTTCTACAAAATAATTACAATAAAGTGTTAACCCTTAAAGAAATACATAAAAATCAGTGGATGGAACTTAATGAACTT
ATAAATAAGATAATAGATATAAATATTAAAGGTGGAGATAAGAAAAAAATAGACAACCACATAATTCATAAAGATTCTGT
ATACATAGTAAGTTTTACAATGGTTTTGGGAGTAGTATTTAGCGTGTTTTTTGTTATAAATTTATATAAGTATATAATGA
AAAATTTAAGAAAAGTAATAAAATTTTCTCATAGAATTGCAAAGTATGATTTTTCAGAGGATATTGTTACAGAAAGAAAG
GATGAGTTTAAAGATATAGGAGATGCCCTTAATATAGCTCAAGATAATGTAAAAAAACTTATTAGTACAATAGTTTTAAA
GTCAAAGGAACTGAGTAAGTTTAGTGAAGAACTTTTTGCCACCATTGAGGAAATGAATGCAAAGTTTAGTGAGATAGATA
AAGATACAAATAAAATAGCAAGAGAAATGCAAGAATCTAGCTCTGCAACAGAGGAAATTTCTGCATCTGTTCAAGAAGTA
GATTCTAGTATTAATATACTCACTCAAAAAGCAGTTGATGGAAGTAATGTTTCTATTAAGTCCAAAGAAAGAGCAGATAA
AGTTTATAAAAATGGAGAATTAGCAGTTAAGGAAACAGAAGAATTATTTAATAAAAATAAAGAAAAAATATTAAAAGCAA
TAGAAGAAGGAAAGGTTGTAGAAGATATAAAAGTTATGGCAGATACTATAGCAAGTATAGCGGAACAAACAAATCTTCTT
GCATTAAATGCCGCAATAGAAGCTGCAAGAGCAGGAGAGAACGGAAAAGGATTCGCAGTAGTTGCTGATAAAGTAAGGGA
ACTTGCTGAACAGTCATCAGAATCTGTGCTTAATGTAAAATTAACCATAGAGAAAGTAAATAAAGCTTTTAATGAGCTAT
CAGAAAACTCAATATTAACTTTGAAATTTATAGATTCTAAAGTTAGAAGCCAATTTGATGATTTTTCTCATATGGGATAT
CATTATTATAAAGATGCTGAGTTTACATCTAAAATGTCAGAGGATATAGCCTCTATGGTAGAAGAAATAAATGCCATAAC
AAAGGAAGTAAATATTTCAGTGCAGGGAATGGCAGATATGGTACAAGAATCTTTTAAAAGTTCATATTCTATTGAAGAGA
GTATAAAGGAATCATCTGATGCTATGGAGCAAATAGCAATAACAGCACAAACACAATCAGAACTTGCACAGAATTTAAAT
GAAATTGCTGAAAGGTTTATATTATAA

Upstream 100 bases:

>100_bases
AATTTGCCATTAATTATTATTAAAATATTTAAAATGGGAGGGAAGTTTCAATAATTATCGATATATTAATAAATCAATAA
TATAGGAGTGCGGTGCAAAA

Downstream 100 bases:

>100_bases
TATTTATAAAGATAAAAACAGTTACTATTGTGTTTAAAGAATAGTAACTGTTAATTATTTAACTTATTTGTAGGTAGTTA
ATTATAGTCCTATAGAACAC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MKNLNLSKRLILSFTLLIIVIITNGIVGIRSVNKMDFNANEIAGSMDAINRIRHIETHLIESKASTIILLNEKDVNKINR
LKEELNSLSEETNEIIRECINSQDSWFKGEAEVFKEFQNKLKVYRSTRDDICNLVLQNNYNKVLTLKEIHKNQWMELNEL
INKIIDINIKGGDKKKIDNHIIHKDSVYIVSFTMVLGVVFSVFFVINLYKYIMKNLRKVIKFSHRIAKYDFSEDIVTERK
DEFKDIGDALNIAQDNVKKLISTIVLKSKELSKFSEELFATIEEMNAKFSEIDKDTNKIAREMQESSSATEEISASVQEV
DSSINILTQKAVDGSNVSIKSKERADKVYKNGELAVKETEELFNKNKEKILKAIEEGKVVEDIKVMADTIASIAEQTNLL
ALNAAIEAARAGENGKGFAVVADKVRELAEQSSESVLNVKLTIEKVNKAFNELSENSILTLKFIDSKVRSQFDDFSHMGY
HYYKDAEFTSKMSEDIASMVEEINAITKEVNISVQGMADMVQESFKSSYSIEESIKESSDAMEQIAITAQTQSELAQNLN
EIAERFIL

Sequences:

>Translated_568_residues
MKNLNLSKRLILSFTLLIIVIITNGIVGIRSVNKMDFNANEIAGSMDAINRIRHIETHLIESKASTIILLNEKDVNKINR
LKEELNSLSEETNEIIRECINSQDSWFKGEAEVFKEFQNKLKVYRSTRDDICNLVLQNNYNKVLTLKEIHKNQWMELNEL
INKIIDINIKGGDKKKIDNHIIHKDSVYIVSFTMVLGVVFSVFFVINLYKYIMKNLRKVIKFSHRIAKYDFSEDIVTERK
DEFKDIGDALNIAQDNVKKLISTIVLKSKELSKFSEELFATIEEMNAKFSEIDKDTNKIAREMQESSSATEEISASVQEV
DSSINILTQKAVDGSNVSIKSKERADKVYKNGELAVKETEELFNKNKEKILKAIEEGKVVEDIKVMADTIASIAEQTNLL
ALNAAIEAARAGENGKGFAVVADKVRELAEQSSESVLNVKLTIEKVNKAFNELSENSILTLKFIDSKVRSQFDDFSHMGY
HYYKDAEFTSKMSEDIASMVEEINAITKEVNISVQGMADMVQESFKSSYSIEESIKESSDAMEQIAITAQTQSELAQNLN
EIAERFIL
>Mature_568_residues
MKNLNLSKRLILSFTLLIIVIITNGIVGIRSVNKMDFNANEIAGSMDAINRIRHIETHLIESKASTIILLNEKDVNKINR
LKEELNSLSEETNEIIRECINSQDSWFKGEAEVFKEFQNKLKVYRSTRDDICNLVLQNNYNKVLTLKEIHKNQWMELNEL
INKIIDINIKGGDKKKIDNHIIHKDSVYIVSFTMVLGVVFSVFFVINLYKYIMKNLRKVIKFSHRIAKYDFSEDIVTERK
DEFKDIGDALNIAQDNVKKLISTIVLKSKELSKFSEELFATIEEMNAKFSEIDKDTNKIAREMQESSSATEEISASVQEV
DSSINILTQKAVDGSNVSIKSKERADKVYKNGELAVKETEELFNKNKEKILKAIEEGKVVEDIKVMADTIASIAEQTNLL
ALNAAIEAARAGENGKGFAVVADKVRELAEQSSESVLNVKLTIEKVNKAFNELSENSILTLKFIDSKVRSQFDDFSHMGY
HYYKDAEFTSKMSEDIASMVEEINAITKEVNISVQGMADMVQESFKSSYSIEESIKESSDAMEQIAITAQTQSELAQNLN
EIAERFIL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=272, Percent_Identity=26.8382352941176, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788195, Length=243, Percent_Identity=27.1604938271605, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787690, Length=338, Percent_Identity=26.6272189349112, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788194, Length=323, Percent_Identity=25.6965944272446, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789453, Length=256, Percent_Identity=25.78125, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 64476; Mature: 64476

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLNLSKRLILSFTLLIIVIITNGIVGIRSVNKMDFNANEIAGSMDAINRIRHIETHLI
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ESKASTIILLNEKDVNKINRLKEELNSLSEETNEIIRECINSQDSWFKGEAEVFKEFQNK
HCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LKVYRSTRDDICNLVLQNNYNKVLTLKEIHKNQWMELNELINKIIDINIKGGDKKKIDNH
HHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHH
IIHKDSVYIVSFTMVLGVVFSVFFVINLYKYIMKNLRKVIKFSHRIAKYDFSEDIVTERK
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DEFKDIGDALNIAQDNVKKLISTIVLKSKELSKFSEELFATIEEMNAKFSEIDKDTNKIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHH
REMQESSSATEEISASVQEVDSSINILTQKAVDGSNVSIKSKERADKVYKNGELAVKETE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHCCCCEEHHHHH
ELFNKNKEKILKAIEEGKVVEDIKVMADTIASIAEQTNLLALNAAIEAARAGENGKGFAV
HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCCHHH
VADKVRELAEQSSESVLNVKLTIEKVNKAFNELSENSILTLKFIDSKVRSQFDDFSHMGY
HHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCC
HYYKDAEFTSKMSEDIASMVEEINAITKEVNISVQGMADMVQESFKSSYSIEESIKESSD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
AMEQIAITAQTQSELAQNLNEIAERFIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNLNLSKRLILSFTLLIIVIITNGIVGIRSVNKMDFNANEIAGSMDAINRIRHIETHLI
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ESKASTIILLNEKDVNKINRLKEELNSLSEETNEIIRECINSQDSWFKGEAEVFKEFQNK
HCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LKVYRSTRDDICNLVLQNNYNKVLTLKEIHKNQWMELNELINKIIDINIKGGDKKKIDNH
HHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHH
IIHKDSVYIVSFTMVLGVVFSVFFVINLYKYIMKNLRKVIKFSHRIAKYDFSEDIVTERK
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DEFKDIGDALNIAQDNVKKLISTIVLKSKELSKFSEELFATIEEMNAKFSEIDKDTNKIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHH
REMQESSSATEEISASVQEVDSSINILTQKAVDGSNVSIKSKERADKVYKNGELAVKETE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHCCCCEEHHHHH
ELFNKNKEKILKAIEEGKVVEDIKVMADTIASIAEQTNLLALNAAIEAARAGENGKGFAV
HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCCHHH
VADKVRELAEQSSESVLNVKLTIEKVNKAFNELSENSILTLKFIDSKVRSQFDDFSHMGY
HHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCC
HYYKDAEFTSKMSEDIASMVEEINAITKEVNISVQGMADMVQESFKSSYSIEESIKESSD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
AMEQIAITAQTQSELAQNLNEIAERFIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]