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The map label for this gene is algC [H]

Identifier: 28210207

GI number: 28210207

Start: 452281

End: 453636

Strand: Direct

Name: algC [H]

Synonym: CTC00454

Alternate gene names: 28210207

Gene position: 452281-453636 (Clockwise)

Preceding gene: 28210205

Following gene: 28210208

Centisome position: 16.16

GC content: 30.6

Gene sequence:

>1356_bases
ATGGAAAACATAAATAAAAGCATCTTTAGGAAATATGACATAAGAGGAATATATGGAGAAGAAGTAACAGAAAATTTTGC
AGAACTATTAGGAAAGACCTTTGGAAGTTTTTTAATAAGAAAGGGAGAGAAAAAAGTTATAGTAGGTATGGATAATAGAA
AATCCTCACCTAGTATTAAAAAGAGTCTAATAAAGGGATTAACTAGCACAGGAGTGGATGTTATAGATATAGGAATTGTA
GTAACACCCATATTTTATTATGCTACTTATTTATATAAAATAAAAGGTGGAATAATGGTTACAGCCAGCCACAATCCAGC
AAAATATAATGGATTCAAAATACAGTTTGAAGAAGGCACTATATATGGGGAAAAACTTTTAAAATTAAGAGAAGAGATGG
TAAAAGGAAATTTTATTAAAGGAAATAGATATGGGTATATAATAGAAAGATCCCCTGTAGAAGAATATATTAAAAATATA
GAAGAAAAAATAAAATTAGGGTCTAAAAAATTAAAAGTGGTTGTAGATTGCGGTAATGGAACAGCAGCTTTATTTGCTCC
AGAAATTTTAAAAAGACTTGGGTGTGATGTAATATCTCTATATTGCACTTCCGATTCAGATTTTCCTAATCACTTTCCAG
ACCCTACAGTAGAAGATAATTTAATAGATTTAATAAAAAAAGTGAGAATAGAAAAGGCGGATTTAGGTATAGCTTATGAT
GGAGATGGAGACAGAATTGGAGTAGTAGACGAAAAAGGAGATATAATTTGGGGAGATATGCTTATGATACTTTTTTGGAG
AGAAATACTTCCTAAATACCCCAATATAGATGCTATAGTAGAAGTAAAATGTTCAAATGCTCTAGTAGAAGAAATAAGAA
AGCTAGGAGGAAAACCTTTCTTCTACAAAACAGGACATTCACTTATAAAAGCTAAAATGCAGGAAATTGATGCTCCTTTT
ACAGGAGAAATGTCTGGTCATATGTTTTTTAGAGATGAATATTATGGTTTTGATGATGCTCTTTATGCCTCAGCACGACT
TTTAAGAATTCTATCAAATACTGACAAAAGTTTAGGAGAACTTTTTTATGATATTCCTCAATATTTTTCCACTCCAGAGA
TAAGAGTACCCTGTAAGGATGAAGAAAAGTTTGAAAGGGTAGAAAGGGCTAAAAAGTACTTTGAAGAAAAAAATATGGAC
ATAATAACCATAGATGGAGTTAGGGTCAACTTTGAAAATGGATGGGGACTTATAAGAGCATCCAATACAGGGGAAGAGCT
AATATTAAGATATGAGTCAAAAAATAAAAATGAATTAAAACTTATTAAAAGAGAACTTAGAAAAGCTTTAGGATAA

Upstream 100 bases:

>100_bases
ACAAAATAATAAAATTACGATGTAATTTTTACTTTGTAACTATTTAACAACTAATAATCATATATTAAATTAGTATGCAC
TATATTATGGGAGGAATTAA

Downstream 100 bases:

>100_bases
TAAATACAATAATAGAGTGGAATTTCCAAATATGGAAGTTTCACTTTGTTTTTTAATTGTGGTAATATGATATGGAATTA
TTAGATTGTATACAAAAAGA

Product: phosphoglucomutase

Products: NA

Alternate protein names: PMM / PGM [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MENINKSIFRKYDIRGIYGEEVTENFAELLGKTFGSFLIRKGEKKVIVGMDNRKSSPSIKKSLIKGLTSTGVDVIDIGIV
VTPIFYYATYLYKIKGGIMVTASHNPAKYNGFKIQFEEGTIYGEKLLKLREEMVKGNFIKGNRYGYIIERSPVEEYIKNI
EEKIKLGSKKLKVVVDCGNGTAALFAPEILKRLGCDVISLYCTSDSDFPNHFPDPTVEDNLIDLIKKVRIEKADLGIAYD
GDGDRIGVVDEKGDIIWGDMLMILFWREILPKYPNIDAIVEVKCSNALVEEIRKLGGKPFFYKTGHSLIKAKMQEIDAPF
TGEMSGHMFFRDEYYGFDDALYASARLLRILSNTDKSLGELFYDIPQYFSTPEIRVPCKDEEKFERVERAKKYFEEKNMD
IITIDGVRVNFENGWGLIRASNTGEELILRYESKNKNELKLIKRELRKALG

Sequences:

>Translated_451_residues
MENINKSIFRKYDIRGIYGEEVTENFAELLGKTFGSFLIRKGEKKVIVGMDNRKSSPSIKKSLIKGLTSTGVDVIDIGIV
VTPIFYYATYLYKIKGGIMVTASHNPAKYNGFKIQFEEGTIYGEKLLKLREEMVKGNFIKGNRYGYIIERSPVEEYIKNI
EEKIKLGSKKLKVVVDCGNGTAALFAPEILKRLGCDVISLYCTSDSDFPNHFPDPTVEDNLIDLIKKVRIEKADLGIAYD
GDGDRIGVVDEKGDIIWGDMLMILFWREILPKYPNIDAIVEVKCSNALVEEIRKLGGKPFFYKTGHSLIKAKMQEIDAPF
TGEMSGHMFFRDEYYGFDDALYASARLLRILSNTDKSLGELFYDIPQYFSTPEIRVPCKDEEKFERVERAKKYFEEKNMD
IITIDGVRVNFENGWGLIRASNTGEELILRYESKNKNELKLIKRELRKALG
>Mature_451_residues
MENINKSIFRKYDIRGIYGEEVTENFAELLGKTFGSFLIRKGEKKVIVGMDNRKSSPSIKKSLIKGLTSTGVDVIDIGIV
VTPIFYYATYLYKIKGGIMVTASHNPAKYNGFKIQFEEGTIYGEKLLKLREEMVKGNFIKGNRYGYIIERSPVEEYIKNI
EEKIKLGSKKLKVVVDCGNGTAALFAPEILKRLGCDVISLYCTSDSDFPNHFPDPTVEDNLIDLIKKVRIEKADLGIAYD
GDGDRIGVVDEKGDIIWGDMLMILFWREILPKYPNIDAIVEVKCSNALVEEIRKLGGKPFFYKTGHSLIKAKMQEIDAPF
TGEMSGHMFFRDEYYGFDDALYASARLLRILSNTDKSLGELFYDIPQYFSTPEIRVPCKDEEKFERVERAKKYFEEKNMD
IITIDGVRVNFENGWGLIRASNTGEELILRYESKNKNELKLIKRELRKALG

Specific function: The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to it

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=458, Percent_Identity=33.6244541484716, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1789566, Length=385, Percent_Identity=31.4285714285714, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17864244, Length=387, Percent_Identity=25.0645994832041, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2; =5.4.2.8 [H]

Molecular weight: Translated: 51492; Mature: 51492

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENINKSIFRKYDIRGIYGEEVTENFAELLGKTFGSFLIRKGEKKVIVGMDNRKSSPSIK
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
KSLIKGLTSTGVDVIDIGIVVTPIFYYATYLYKIKGGIMVTASHNPAKYNGFKIQFEEGT
HHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEECCEEEEEECCC
IYGEKLLKLREEMVKGNFIKGNRYGYIIERSPVEEYIKNIEEKIKLGSKKLKVVVDCGNG
CHHHHHHHHHHHHHCCCEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCC
TAALFAPEILKRLGCDVISLYCTSDSDFPNHFPDPTVEDNLIDLIKKVRIEKADLGIAYD
CEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCEEEC
GDGDRIGVVDEKGDIIWGDMLMILFWREILPKYPNIDAIVEVKCSNALVEEIRKLGGKPF
CCCCEEEEEECCCCEEHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCE
FYKTGHSLIKAKMQEIDAPFTGEMSGHMFFRDEYYGFDDALYASARLLRILSNTDKSLGE
EEECCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHH
LFYDIPQYFSTPEIRVPCKDEEKFERVERAKKYFEEKNMDIITIDGVRVNFENGWGLIRA
HHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCEEEEEE
SNTGEELILRYESKNKNELKLIKRELRKALG
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENINKSIFRKYDIRGIYGEEVTENFAELLGKTFGSFLIRKGEKKVIVGMDNRKSSPSIK
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
KSLIKGLTSTGVDVIDIGIVVTPIFYYATYLYKIKGGIMVTASHNPAKYNGFKIQFEEGT
HHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEECCEEEEEECCC
IYGEKLLKLREEMVKGNFIKGNRYGYIIERSPVEEYIKNIEEKIKLGSKKLKVVVDCGNG
CHHHHHHHHHHHHHCCCEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCC
TAALFAPEILKRLGCDVISLYCTSDSDFPNHFPDPTVEDNLIDLIKKVRIEKADLGIAYD
CEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCEEEC
GDGDRIGVVDEKGDIIWGDMLMILFWREILPKYPNIDAIVEVKCSNALVEEIRKLGGKPF
CCCCEEEEEECCCCEEHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCE
FYKTGHSLIKAKMQEIDAPFTGEMSGHMFFRDEYYGFDDALYASARLLRILSNTDKSLGE
EEECCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHH
LFYDIPQYFSTPEIRVPCKDEEKFERVERAKKYFEEKNMDIITIDGVRVNFENGWGLIRA
HHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCEEEEEE
SNTGEELILRYESKNKNELKLIKRELRKALG
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1903398; 10984043; 7515870; 10481091; 8050998; 11716469; 11839312 [H]