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The map label for this gene is phoR [H]

Identifier: 28210165

GI number: 28210165

Start: 407167

End: 408621

Strand: Direct

Name: phoR [H]

Synonym: CTC00412

Alternate gene names: 28210165

Gene position: 407167-408621 (Clockwise)

Preceding gene: 28210164

Following gene: 28210166

Centisome position: 14.55

GC content: 22.47

Gene sequence:

>1455_bases
TTGAAAAATAGTATAAAATTCAAATTTTTATTAGGATTACTAATTATATATTGTATATCAGCAATAGGGTTAAATATTCT
AATTAGATTGGTGTTTAAATCAAATATAGAAAATATTATTAAAAGCTCAACTCAAGATATTATCAGAAATTCTAAAGAAC
ACATAGAGTATAAATTTACTATGTTAGATTTACCTTTAAATGAAAACAGTTTAATAATTGAATCTAATAGTATATTAGAT
TATTTCTCAAAAGAATATAATGCAGATGGAGAAATAAGAAGAAAAAATGGAGAAGTTATATATAGAAATATAGAGGAAAG
ATTTAAAACTATTGCTAATGAAAGTGTTAAACCAGCCTTAAATGGAAAAGTAGTAGCAAAACTTAATAACATAAATAATG
AGCTTTATGTTATATTTTCTTATCCTCTGTATTATGAAAATGAACATATTGGAATTATAACTATAATAAAAGATTATAAT
CAATTGTATAACTATAATAAAAATGCAATAAATTTAATTACCTTTATAGAAATTATAATTTTTATAATAATTTTTATAGC
ATCTTATATTTTTACTACGAAAATAACGACTCCTATAACAAATTTAACTAAGGCAGTAAATAAAGTTTCTAAAGGAGATT
ATAACATTGATTTTGAAGTAAAAAGTAATAATGAAATAGGGGTATTATCAAAAGAATTTATGAATATGAAAAATAAGATA
AAAAATCAAATAGATAATATAAATGCAGAAAAGGAAAAGGTAATAAAGTTAGAAAAATCAAGAAGGGAATTTTTTAACAA
TGTAACCCATGAATTAAAAACTCCATTAACGGCTATTTCAGGATATGCTCAAATATTATCAGATGAAAATGTAAAGGATG
AAGATTTTAAAATAAGAGCTTATAATAGAATATATATGGAAAGTGAAAGACTTCATGGATTAGTTTTAGATTTAATAGAT
GTTTCTAAAGGATTGTCTAGTGTAGAGGAAACCAGAGAAGTTATAGATATGAAAAAACTTGTAATAGAAATTTCGGAAGA
TATGAGTATTAAGGCTAATAAGTATAATTTGAATTTAATAAGTAACATAAATGAGGGATTTATATATGGTCAAAGCAATA
AAATAAGGCAACTTATAATAAATGTCTTAGATAATGCAATAAAGTACTCTTGGAGAAGAGAAAAGATTTTTTTAAAGTCA
TTTAATGAAAATAATTTTTATATATTAGAGGTTTACAATAAAGGAAATAAGATTCCAGTGAATATCTATAAAAATATTTT
TAATCCATTTATAAAGTCTAAAGTATCTGTGGATAGTAATAGTAGAGGTCTAGGATTATATATATGTAGTGAAATAGTAA
GAGAACATAATGGAGATATAAAAATAGAAAATGGAGAACGAATTAAAGTAACAATAAAGATACCTTGTCTTGGAAACAAT
TTGGAAATAACTTAA

Upstream 100 bases:

>100_bases
GATATACATGTTAGAAGACTTAGAGCTAAACTTGACTCTAATAATGGACAATCTATTATAGAAACAGTATTTGGCGTAGG
CTATGTAATGAGGTGATGCA

Downstream 100 bases:

>100_bases
CTAATAACAGAAACAATTAAATGATATAGTGATTACAATACAATCCAAGGAGGTAGGAATTATGAATATAAAAAGTTACA
AAAAGTTTATTATTATTTCT

Product: alkaline phosphatase synthesis sensor protein phoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MKNSIKFKFLLGLLIIYCISAIGLNILIRLVFKSNIENIIKSSTQDIIRNSKEHIEYKFTMLDLPLNENSLIIESNSILD
YFSKEYNADGEIRRKNGEVIYRNIEERFKTIANESVKPALNGKVVAKLNNINNELYVIFSYPLYYENEHIGIITIIKDYN
QLYNYNKNAINLITFIEIIIFIIIFIASYIFTTKITTPITNLTKAVNKVSKGDYNIDFEVKSNNEIGVLSKEFMNMKNKI
KNQIDNINAEKEKVIKLEKSRREFFNNVTHELKTPLTAISGYAQILSDENVKDEDFKIRAYNRIYMESERLHGLVLDLID
VSKGLSSVEETREVIDMKKLVIEISEDMSIKANKYNLNLISNINEGFIYGQSNKIRQLIINVLDNAIKYSWRREKIFLKS
FNENNFYILEVYNKGNKIPVNIYKNIFNPFIKSKVSVDSNSRGLGLYICSEIVREHNGDIKIENGERIKVTIKIPCLGNN
LEIT

Sequences:

>Translated_484_residues
MKNSIKFKFLLGLLIIYCISAIGLNILIRLVFKSNIENIIKSSTQDIIRNSKEHIEYKFTMLDLPLNENSLIIESNSILD
YFSKEYNADGEIRRKNGEVIYRNIEERFKTIANESVKPALNGKVVAKLNNINNELYVIFSYPLYYENEHIGIITIIKDYN
QLYNYNKNAINLITFIEIIIFIIIFIASYIFTTKITTPITNLTKAVNKVSKGDYNIDFEVKSNNEIGVLSKEFMNMKNKI
KNQIDNINAEKEKVIKLEKSRREFFNNVTHELKTPLTAISGYAQILSDENVKDEDFKIRAYNRIYMESERLHGLVLDLID
VSKGLSSVEETREVIDMKKLVIEISEDMSIKANKYNLNLISNINEGFIYGQSNKIRQLIINVLDNAIKYSWRREKIFLKS
FNENNFYILEVYNKGNKIPVNIYKNIFNPFIKSKVSVDSNSRGLGLYICSEIVREHNGDIKIENGERIKVTIKIPCLGNN
LEIT
>Mature_484_residues
MKNSIKFKFLLGLLIIYCISAIGLNILIRLVFKSNIENIIKSSTQDIIRNSKEHIEYKFTMLDLPLNENSLIIESNSILD
YFSKEYNADGEIRRKNGEVIYRNIEERFKTIANESVKPALNGKVVAKLNNINNELYVIFSYPLYYENEHIGIITIIKDYN
QLYNYNKNAINLITFIEIIIFIIIFIASYIFTTKITTPITNLTKAVNKVSKGDYNIDFEVKSNNEIGVLSKEFMNMKNKI
KNQIDNINAEKEKVIKLEKSRREFFNNVTHELKTPLTAISGYAQILSDENVKDEDFKIRAYNRIYMESERLHGLVLDLID
VSKGLSSVEETREVIDMKKLVIEISEDMSIKANKYNLNLISNINEGFIYGQSNKIRQLIINVLDNAIKYSWRREKIFLKS
FNENNFYILEVYNKGNKIPVNIYKNIFNPFIKSKVSVDSNSRGLGLYICSEIVREHNGDIKIENGERIKVTIKIPCLGNN
LEIT

Specific function: Could be member of the two-component regulatory system yclK/yclJ. Potentially phosphorylates yclJ [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=321, Percent_Identity=24.9221183800623, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=23.7704918032787, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=339, Percent_Identity=22.7138643067847, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082128, Length=311, Percent_Identity=21.5434083601286, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788393, Length=292, Percent_Identity=22.6027397260274, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=288, Percent_Identity=23.2638888888889, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=23.9130434782609, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=25, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=24.1228070175439, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=26.0700389105058, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=22.8215767634855, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56129; Mature: 56129

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSIKFKFLLGLLIIYCISAIGLNILIRLVFKSNIENIIKSSTQDIIRNSKEHIEYKFT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHEEEEEE
MLDLPLNENSLIIESNSILDYFSKEYNADGEIRRKNGEVIYRNIEERFKTIANESVKPAL
EEEECCCCCEEEEECCCHHHHHHHHCCCCCCEEECCCCEEEECHHHHHHHHHCCCCCCCC
NGKVVAKLNNINNELYVIFSYPLYYENEHIGIITIIKDYNQLYNYNKNAINLITFIEIII
CCEEEEEEECCCCEEEEEEECCEEECCCCEEEEEEEHHHHHHHCCCCCHHHHHHHHHHHH
FIIIFIASYIFTTKITTPITNLTKAVNKVSKGDYNIDFEVKSNNEIGVLSKEFMNMKNKI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCEEHHHHHHHHHHHH
KNQIDNINAEKEKVIKLEKSRREFFNNVTHELKTPLTAISGYAQILSDENVKDEDFKIRA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEE
YNRIYMESERLHGLVLDLIDVSKGLSSVEETREVIDMKKLVIEISEDMSIKANKYNLNLI
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
SNINEGFIYGQSNKIRQLIINVLDNAIKYSWRREKIFLKSFNENNFYILEVYNKGNKIPV
ECCCCCEEECCCHHHHHHHHHHHHHHHHCCHHHCEEEEEECCCCCEEEEEEECCCCEEEH
NIYKNIFNPFIKSKVSVDSNSRGLGLYICSEIVREHNGDIKIENGERIKVTIKIPCLGNN
HHHHHHHHHHHHCEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEEEEEEECCC
LEIT
CEEC
>Mature Secondary Structure
MKNSIKFKFLLGLLIIYCISAIGLNILIRLVFKSNIENIIKSSTQDIIRNSKEHIEYKFT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHEEEEEE
MLDLPLNENSLIIESNSILDYFSKEYNADGEIRRKNGEVIYRNIEERFKTIANESVKPAL
EEEECCCCCEEEEECCCHHHHHHHHCCCCCCEEECCCCEEEECHHHHHHHHHCCCCCCCC
NGKVVAKLNNINNELYVIFSYPLYYENEHIGIITIIKDYNQLYNYNKNAINLITFIEIII
CCEEEEEEECCCCEEEEEEECCEEECCCCEEEEEEEHHHHHHHCCCCCHHHHHHHHHHHH
FIIIFIASYIFTTKITTPITNLTKAVNKVSKGDYNIDFEVKSNNEIGVLSKEFMNMKNKI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCEEHHHHHHHHHHHH
KNQIDNINAEKEKVIKLEKSRREFFNNVTHELKTPLTAISGYAQILSDENVKDEDFKIRA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEE
YNRIYMESERLHGLVLDLIDVSKGLSSVEETREVIDMKKLVIEISEDMSIKANKYNLNLI
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
SNINEGFIYGQSNKIRQLIINVLDNAIKYSWRREKIFLKSFNENNFYILEVYNKGNKIPV
ECCCCCEEECCCHHHHHHHHHHHHHHHHCCHHHCEEEEEECCCCCEEEEEEECCCCEEEH
NIYKNIFNPFIKSKVSVDSNSRGLGLYICSEIVREHNGDIKIENGERIKVTIKIPCLGNN
HHHHHHHHHHHHCEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEEEEEEECCC
LEIT
CEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]