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The map label for this gene is phoP [H]

Identifier: 28210164

GI number: 28210164

Start: 406476

End: 407162

Strand: Direct

Name: phoP [H]

Synonym: CTC00411

Alternate gene names: 28210164

Gene position: 406476-407162 (Clockwise)

Preceding gene: 161486851

Following gene: 28210165

Centisome position: 14.52

GC content: 26.78

Gene sequence:

>687_bases
ATGGAACATAAAATAATTGTTATTGAAGATGAGTTTTCGATAAATGATATATTAACTTTTGCATTAAAAGAAGAGGGATA
TAGAGTGAAAAGTACTTTCTCTTCTCAAGAGGCGAGAAAAATAATGAAAGAATTTAGACCTAATTTAGTATTATTAGATA
TAAATTTACCAGATGAAAGTGGCTTTGAACTTTGTAAATTCATAACATGTAAATATAAAATACCTATTCTTATGATTACT
GCAAGAAATGATTTAGTTGACAAAGTATTAGGTTTAGAATTAGGAGCAGATGATTATATAACTAAACCTTTTCATATAAA
AGAAGTAATGACAAGAGTAAGAGTTGCATTAAGAAGGGTTAAAAAATATAGTGTTGTAAAAGAAAATAAAGAATTTATAG
AACTGAATGATGAAGTAAAAATAAATTTAGAAAGTAGGGAAGTTTTTAAAAATAATAGGGAGATAAAATTAAAACCTAAA
GAATATGATTTACTTGTATTTCTAGCACAAAATAGAAACATAGTTTTTTCAAGGGAAACTATATTGGATAGGGTTTGGGA
ATTAGAGTATGATGGGGAAATAAGAACTGTTGATATACATGTTAGAAGACTTAGAGCTAAACTTGACTCTAATAATGGAC
AATCTATTATAGAAACAGTATTTGGCGTAGGCTATGTAATGAGGTGA

Upstream 100 bases:

>100_bases
TTTAATTAAAATGAACTTATTTGCTTAAATACTGTAAGAAATTCTATAATATAAATGAGTATAAAGTATCTAAATTATAG
ATTAAAAGTGAGGTATTGTT

Downstream 100 bases:

>100_bases
TGCATTGAAAAATAGTATAAAATTCAAATTTTTATTAGGATTACTAATTATATATTGTATATCAGCAATAGGGTTAAATA
TTCTAATTAGATTGGTGTTT

Product: alkaline phosphatase synthesis transcriptional regulatory protein phoP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MEHKIIVIEDEFSINDILTFALKEEGYRVKSTFSSQEARKIMKEFRPNLVLLDINLPDESGFELCKFITCKYKIPILMIT
ARNDLVDKVLGLELGADDYITKPFHIKEVMTRVRVALRRVKKYSVVKENKEFIELNDEVKINLESREVFKNNREIKLKPK
EYDLLVFLAQNRNIVFSRETILDRVWELEYDGEIRTVDIHVRRLRAKLDSNNGQSIIETVFGVGYVMR

Sequences:

>Translated_228_residues
MEHKIIVIEDEFSINDILTFALKEEGYRVKSTFSSQEARKIMKEFRPNLVLLDINLPDESGFELCKFITCKYKIPILMIT
ARNDLVDKVLGLELGADDYITKPFHIKEVMTRVRVALRRVKKYSVVKENKEFIELNDEVKINLESREVFKNNREIKLKPK
EYDLLVFLAQNRNIVFSRETILDRVWELEYDGEIRTVDIHVRRLRAKLDSNNGQSIIETVFGVGYVMR
>Mature_228_residues
MEHKIIVIEDEFSINDILTFALKEEGYRVKSTFSSQEARKIMKEFRPNLVLLDINLPDESGFELCKFITCKYKIPILMIT
ARNDLVDKVLGLELGADDYITKPFHIKEVMTRVRVALRRVKKYSVVKENKEFIELNDEVKINLESREVFKNNREIKLKPK
EYDLLVFLAQNRNIVFSRETILDRVWELEYDGEIRTVDIHVRRLRAKLDSNNGQSIIETVFGVGYVMR

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=35.9649122807018, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=38.0530973451327, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=34.2222222222222, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=30.8370044052863, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=33.7777777777778, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=34.8214285714286, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=33.1896551724138, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=31.5315315315315, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1790863, Length=225, Percent_Identity=32.4444444444444, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=33.4801762114537, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=31.6964285714286, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=32.3144104803493, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=30.6666666666667, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=29.004329004329, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=26.4957264957265, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26862; Mature: 26862

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHKIIVIEDEFSINDILTFALKEEGYRVKSTFSSQEARKIMKEFRPNLVLLDINLPDES
CCCEEEEEECCCCHHHHEEEEECCCCEEEEHHCCHHHHHHHHHHHCCCEEEEEEECCCCC
GFELCKFITCKYKIPILMITARNDLVDKVLGLELGADDYITKPFHIKEVMTRVRVALRRV
CHHHHHHEEEEEECCEEEEECCCHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHH
KKYSVVKENKEFIELNDEVKINLESREVFKNNREIKLKPKEYDLLVFLAQNRNIVFSRET
HHHHHHHCCCCEEEECCEEEEEECHHHHHCCCCEEEECCCCEEEEEEEECCCCEEEEHHH
ILDRVWELEYDGEIRTVDIHVRRLRAKLDSNNGQSIIETVFGVGYVMR
HHHHHHCEEECCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHEECC
>Mature Secondary Structure
MEHKIIVIEDEFSINDILTFALKEEGYRVKSTFSSQEARKIMKEFRPNLVLLDINLPDES
CCCEEEEEECCCCHHHHEEEEECCCCEEEEHHCCHHHHHHHHHHHCCCEEEEEEECCCCC
GFELCKFITCKYKIPILMITARNDLVDKVLGLELGADDYITKPFHIKEVMTRVRVALRRV
CHHHHHHEEEEEECCEEEEECCCHHHHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHH
KKYSVVKENKEFIELNDEVKINLESREVFKNNREIKLKPKEYDLLVFLAQNRNIVFSRET
HHHHHHHCCCCEEEECCEEEEEECHHHHHCCCCEEEECCCCEEEEEEEECCCCEEEEHHH
ILDRVWELEYDGEIRTVDIHVRRLRAKLDSNNGQSIIETVFGVGYVMR
HHHHHHCEEECCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]