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The map label for this gene is gpmI

Identifier: 28210137

GI number: 28210137

Start: 370698

End: 372239

Strand: Direct

Name: gpmI

Synonym: CTC00381

Alternate gene names: 28210137

Gene position: 370698-372239 (Clockwise)

Preceding gene: 28210136

Following gene: 28210138

Centisome position: 13.24

GC content: 31.91

Gene sequence:

>1542_bases
ATGAATAAAAAACCAGTAATGCTTATGATTTTAGACGGTTTTGGCATAACAAATCATGAAGATGGAAATGCAGTAAAGAT
GGCAAATAAGCCAAATTTTGATAAGTTATTAAGAGAGTATCCTCATACCCAATTAAAAGCTAGTGGATTAAATGTTGGAC
TCCCTGAAGGACAAATGGGCAATTCAGAAGTGGGTCATTTAAACATTGGGTCAGGAAGAGTAATATATCAAGAATTAACT
AGAATAACAAAAGACATAAATGATGGAGTGTTTTTTGAAAATACTGAGATAAATTATGCCATAGACGAAGCTATAAAAAA
TAATTCTTCTCTTCATTTACTAGGATTGTTATCTGATGGAGGAGTTCATTCTCATATAGATCATTTAAAAGCTATTCTAA
AATTAGCTAAAGATAAAGGATTAAACAGAGTATATGTTCATGCTTTTCTAGATGGAAGAGATGTTCCACCATCTAGTGCT
AAGGAATATATAATAAACATTGAGAACTATATGAAAGAACTTAGTGTAGGTCAGATTGCAACATTAGCAGGTAGATACTA
TGCTATGGATAGAGATAAGAGATGGGAAAGAGTAGAGCTTGCATATAATGCTTTGGTATATGGTACTGGTGAATTGTCAA
ATTCTGCTGTTGAAGCTATAGAAAAGTCTTATAAAGATAATACAACAGATGAATTTGTGTTGCCAACAGTGATATTAAAA
GATGGGAAGCCAACAGGTACCATTAAAGATGAAGATTCTATAATATTTTTTAACTTTAGACCAGATAGGGCAAGACAAAT
AACTAGAGCTTTAAATGATAAGGATTTTGATGGGTTTGAGAGAAAAAGATTAAAGCTCAATTTTATAACTATGACTCAAT
ATGATAAGACCATTGAGAATGTAAGAATAGCATATAAACCACAAAGTTATAAGAATACTTTAGGTGAGTATGTAAGTAGT
TTAGGATTAAATCAGTTAAGAATTGCAGAAACAGAGAAATATGCCCATGTAACTTTCTTTTTTAACGGAGGAGTAGAAAC
ACCTAATAAAGGTGAGGATAGAGCTTTAATACCTTCCCCTAAAGTAGCCACATATGACTTGAAGCCAGAAATGAGTGCTT
TTGAAGTTAAAGATGAAGTTATAAATAGAATAGAATCTAATAAATACGATATGATAATATTAAACTTTGCTAATCCAGAT
ATGGTAGGACACACAGGTGTATTTGATGCAGCTAAAACTGCCATAGAAGTAGTAGATAAATGTGTAGGAGAAATATCAGA
TAAGATTTTAGAAAAAGAAGGTACTGTATTTATAACTGCAGATCATGGAAATTCTGAACAAATGATAGATTACTCCACAG
GAAAACCTATGACAGCCCATACTACAAATGAAGTTCCCTTTGTATATGTAAGTAAAGATGCAAAGGATAAAAGATTAAAA
TCAGAGGGTATATTGGCAGACATAGCACCAACTATGCTTACAGAAATGGGTGTCAAAATACCAGAAGAAATGACTGGAAG
AAACTTAATAGAAGGAAAGTAA

Upstream 100 bases:

>100_bases
CAAATGTCTATGTCAGATATAGACGGAGCTTTAGTAGGAGGAGCAAGTCTTAAAGCAAATGACTTCTCAGCTATAGTAAA
CTACAAATAGGGGGAAGACT

Downstream 100 bases:

>100_bases
AGGGAGGATATATAAATTATGAAAAATTATATTGAAATTATCGATGTATCAGCAAGACAAGTACTTGATTCAAGATCAAA
TCCAACAGTTGAGGTAGATG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MNKKPVMLMILDGFGITNHEDGNAVKMANKPNFDKLLREYPHTQLKASGLNVGLPEGQMGNSEVGHLNIGSGRVIYQELT
RITKDINDGVFFENTEINYAIDEAIKNNSSLHLLGLLSDGGVHSHIDHLKAILKLAKDKGLNRVYVHAFLDGRDVPPSSA
KEYIINIENYMKELSVGQIATLAGRYYAMDRDKRWERVELAYNALVYGTGELSNSAVEAIEKSYKDNTTDEFVLPTVILK
DGKPTGTIKDEDSIIFFNFRPDRARQITRALNDKDFDGFERKRLKLNFITMTQYDKTIENVRIAYKPQSYKNTLGEYVSS
LGLNQLRIAETEKYAHVTFFFNGGVETPNKGEDRALIPSPKVATYDLKPEMSAFEVKDEVINRIESNKYDMIILNFANPD
MVGHTGVFDAAKTAIEVVDKCVGEISDKILEKEGTVFITADHGNSEQMIDYSTGKPMTAHTTNEVPFVYVSKDAKDKRLK
SEGILADIAPTMLTEMGVKIPEEMTGRNLIEGK

Sequences:

>Translated_513_residues
MNKKPVMLMILDGFGITNHEDGNAVKMANKPNFDKLLREYPHTQLKASGLNVGLPEGQMGNSEVGHLNIGSGRVIYQELT
RITKDINDGVFFENTEINYAIDEAIKNNSSLHLLGLLSDGGVHSHIDHLKAILKLAKDKGLNRVYVHAFLDGRDVPPSSA
KEYIINIENYMKELSVGQIATLAGRYYAMDRDKRWERVELAYNALVYGTGELSNSAVEAIEKSYKDNTTDEFVLPTVILK
DGKPTGTIKDEDSIIFFNFRPDRARQITRALNDKDFDGFERKRLKLNFITMTQYDKTIENVRIAYKPQSYKNTLGEYVSS
LGLNQLRIAETEKYAHVTFFFNGGVETPNKGEDRALIPSPKVATYDLKPEMSAFEVKDEVINRIESNKYDMIILNFANPD
MVGHTGVFDAAKTAIEVVDKCVGEISDKILEKEGTVFITADHGNSEQMIDYSTGKPMTAHTTNEVPFVYVSKDAKDKRLK
SEGILADIAPTMLTEMGVKIPEEMTGRNLIEGK
>Mature_513_residues
MNKKPVMLMILDGFGITNHEDGNAVKMANKPNFDKLLREYPHTQLKASGLNVGLPEGQMGNSEVGHLNIGSGRVIYQELT
RITKDINDGVFFENTEINYAIDEAIKNNSSLHLLGLLSDGGVHSHIDHLKAILKLAKDKGLNRVYVHAFLDGRDVPPSSA
KEYIINIENYMKELSVGQIATLAGRYYAMDRDKRWERVELAYNALVYGTGELSNSAVEAIEKSYKDNTTDEFVLPTVILK
DGKPTGTIKDEDSIIFFNFRPDRARQITRALNDKDFDGFERKRLKLNFITMTQYDKTIENVRIAYKPQSYKNTLGEYVSS
LGLNQLRIAETEKYAHVTFFFNGGVETPNKGEDRALIPSPKVATYDLKPEMSAFEVKDEVINRIESNKYDMIILNFANPD
MVGHTGVFDAAKTAIEVVDKCVGEISDKILEKEGTVFITADHGNSEQMIDYSTGKPMTAHTTNEVPFVYVSKDAKDKRLK
SEGILADIAPTMLTEMGVKIPEEMTGRNLIEGK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=514, Percent_Identity=50.7782101167315, Blast_Score=533, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI32564249, Length=519, Percent_Identity=44.8940269749518, Blast_Score=427, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17507741, Length=519, Percent_Identity=44.8940269749518, Blast_Score=427, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_CLOTE (Q898R1)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781081.1
- ProteinModelPortal:   Q898R1
- SMR:   Q898R1
- GeneID:   1059960
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC00381
- NMPDR:   fig|212717.1.peg.303
- HOGENOM:   HBG613255
- OMA:   DNKTDEF
- PhylomeDB:   Q898R1
- ProtClustDB:   PRK05434
- BioCyc:   CTET212717:CTC_00381-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 57487; Mature: 57487

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: ACT_SITE 62-62

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKPVMLMILDGFGITNHEDGNAVKMANKPNFDKLLREYPHTQLKASGLNVGLPEGQMG
CCCCCEEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCC
NSEVGHLNIGSGRVIYQELTRITKDINDGVFFENTEINYAIDEAIKNNSSLHLLGLLSDG
CCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHCCCCCEEEEEEECCC
GVHSHIDHLKAILKLAKDKGLNRVYVHAFLDGRDVPPSSAKEYIINIENYMKELSVGQIA
CHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHEEEEHHHHHHHHCCCHHH
TLAGRYYAMDRDKRWERVELAYNALVYGTGELSNSAVEAIEKSYKDNTTDEFVLPTVILK
HHHCCEEECCCCCCHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEE
DGKPTGTIKDEDSIIFFNFRPDRARQITRALNDKDFDGFERKRLKLNFITMTQYDKTIEN
CCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEHHHHHHHC
VRIAYKPQSYKNTLGEYVSSLGLNQLRIAETEKYAHVTFFFNGGVETPNKGEDRALIPSP
EEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCCEECCCC
KVATYDLKPEMSAFEVKDEVINRIESNKYDMIILNFANPDMVGHTGVFDAAKTAIEVVDK
CEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
CVGEISDKILEKEGTVFITADHGNSEQMIDYSTGKPMTAHTTNEVPFVYVSKDAKDKRLK
HHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCEEEECCCCCCEEEEECCCCHHHHH
SEGILADIAPTMLTEMGVKIPEEMTGRNLIEGK
HCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MNKKPVMLMILDGFGITNHEDGNAVKMANKPNFDKLLREYPHTQLKASGLNVGLPEGQMG
CCCCCEEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCC
NSEVGHLNIGSGRVIYQELTRITKDINDGVFFENTEINYAIDEAIKNNSSLHLLGLLSDG
CCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHCCCCCEEEEEEECCC
GVHSHIDHLKAILKLAKDKGLNRVYVHAFLDGRDVPPSSAKEYIINIENYMKELSVGQIA
CHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHEEEEHHHHHHHHCCCHHH
TLAGRYYAMDRDKRWERVELAYNALVYGTGELSNSAVEAIEKSYKDNTTDEFVLPTVILK
HHHCCEEECCCCCCHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEE
DGKPTGTIKDEDSIIFFNFRPDRARQITRALNDKDFDGFERKRLKLNFITMTQYDKTIEN
CCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEHHHHHHHC
VRIAYKPQSYKNTLGEYVSSLGLNQLRIAETEKYAHVTFFFNGGVETPNKGEDRALIPSP
EEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCCEECCCC
KVATYDLKPEMSAFEVKDEVINRIESNKYDMIILNFANPDMVGHTGVFDAAKTAIEVVDK
CEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
CVGEISDKILEKEGTVFITADHGNSEQMIDYSTGKPMTAHTTNEVPFVYVSKDAKDKRLK
HHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCEEEECCCCCCEEEEECCCCHHHHH
SEGILADIAPTMLTEMGVKIPEEMTGRNLIEGK
HCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129