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The map label for this gene is ileS [H]

Identifier: 28210025

GI number: 28210025

Start: 231516

End: 234659

Strand: Direct

Name: ileS [H]

Synonym: CTC00261

Alternate gene names: 28210025

Gene position: 231516-234659 (Clockwise)

Preceding gene: 28210024

Following gene: 28210026

Centisome position: 8.27

GC content: 30.31

Gene sequence:

>3144_bases
ATGACAAGAATAGTTTTAGGAGGGAGTTGTAAAATGTATAAAAAGATAGACGGTTCAAAAAGTTTTGTACAAATGGAAAG
AGAAGTATTAGATTTTTGGAACAAAAATAACATAGTAGATAAAAGTTTTGCTTTAAACGAAGAGGGAGAATATTTTACTT
TTTATGATGGGCCACCAACAGCTAATGGTAAACCCCATGTAGGTCATGTTCTTACAAGGGTTATAAAGGATTTAATCCCA
AGATACAAGGTAATGAAAGGTTACAAAGTTTTAAGAAAAGCTGGTTGGGATACACATGGTCTTCCAGTAGAACTTGAAAT
AGAAAAGAAGTTAGGAATTTCAGGGAAAGAAGAGATAGAAAAGTTTGGAGTAGAAGAGTTTATAAAAGAATGTAAGGATT
CTGTATTTACATATTCTAGCATGTGGAAAGACATGTCAGAAAAATTAGCATTTTGGGTGGATATGGAAAATCCATATGTT
ACTTATCATAATGATTATATAGAGTCAGTATGGTGGGCATTAAAGCAACTTTGGAATAAAGAACTTTTATACAAGGGACA
TAAAGTTATACCATATTGTCCAAGGTGTGGAACAGCACTCTCATCTCATGAAGTTGCACAAGGATATAAAGATGTAAAAG
AAGCTACTGCATTTGTAAAATTTAAAGTAAAAGGAGAAGAAAATAAATATATACTTGCATGGACAACAACTCCTTGGACT
TTGCCAAGTAACGTAGCTTTAGCTATCAATAAAAATTTTGATTATGTAGAAGTAAAAAATAATGATGAAGTTTTAATTCT
TGCAAAAGAATTAGTAGATAGTGTAATAGACGGAGAATATGAAATAATAAAAGAATTTAAGGGAGAAGATATATTAGGCC
TTCAATATGAACAATTATTACCATTCTATACTCCAGAAGAAGAAGCTTTTAGAGTAATTCATGGTGATTTTGTAACTTTA
TCTGATGGTACAGGTATAGTTCACACAGCACCAGCATATGGTGAGGATGATAATATTGTTTGTAAGAAACATGGTCTTCC
TATGATAAATCTTGTAGATAAAGAAGGTAAGTTTATAGATTGTGTAGAACCTTGGAAAGGAATGCCTGTTAAGAAAGCAG
ACTCTAAAATTATAGAGTATATGGATGAGAAGGGAATACTGTATAAATCAGAAAAGTTTACTCACTCTTATCCACATTGC
TGGAGATGTGATACTGCACTTTTATATTATCCAACAGATAGTTGGTTTGTAAGAATGACTTCACTAAGAGATAAGTTATT
AGAAAATAATAATAAAGTTAATTGGTATCCAGACAACATCAGAACAGGAAGATTTGGAAAGTTCTTGGAAAATGTAATTG
ACTGGGGTATTTCAAGAGATAGATATTGGGGAACACCATTACCTATTTGGGAATGTGAATGTGGTCATAGAGAATGTATA
GGAAGTATTTCGGAACTAAAGGAAAAAGGAATAGATGTACCAGAAGATATAGAACTTCATAAACCATATATAGATAAAGT
TAAATTGAAATGTTCTAAATGTGGAAAAGAAATGAAAAGAACAAGAGAAGTTATAGATTGTTGGTTTGACTCAGGATCCA
TGCCTTTTGCTCAACATCACTATCCTTTTGAAAATAAAGAGGTATTTGAAAAAACTTTCCCAGCACAATTTATATCAGAA
GCAGTAGACCAAACAAGAGGATGGTTTTATACATTAACAGCAATATCAACAGCAATATTTGATACAAATCCGTTTGAAAA
TTGTATTGTATTAGGACACGTTTTAGATAAACATGGGCTAAAAATGTCAAAATCAAAGGGAAATGTTGTTGATCCATTTG
ATGTTTTAGATAGTGCTGGAGCAGATGCTTCCAGATGGCATTTTTATACTGCAAGTGCACCATGGCTACCTACAAGATTT
TCGCCTGAGGATGTAGAAGAAACTCAAAGAAAGTTTTTAAGTACTTTATGGAATGTATATTCTTTCTATGTACTTTATGC
TGATATAGATAAATTTAATCCATTAGAATACAAAGATTTTGTAAGTGAAAATGTAATGGATAAGTGGATTGTTTCAAAAT
TAAATTCACTTATAAAAGATGTTGAAGATCATATGGATAGTTATAGAATAACTCAAGCTGCATTGGCCATAGAAGATTTT
GTCGATGAACTTTCAAACTGGTATGTACGAAGAAATAGATCCAGATTTTGGAGTGAAGAATTAAGAGAAGATAAAATAGG
AGCATATGTTACATTATATAAAGTTTTAACTACAGTAAGTTTAATAGCAGCTCCATTTGTACCATTTATAACAGAAGAAA
TTTATAATAATTTAGTTAGAGGATTAGATAAAAATGCTTTAGAAAGCATACATCTATGTAATTGGCCTAAATATGACGAA
AACCTAATTCAAAAAGAATTAGAAAGAGAAATGGATGAAGCTTATAAAATAGTTAAACTTGGAAGAAGCGCAAGAAATTC
TGTTAATATAAAGAACAGACAGCCATTATCTTCTATGTTAGTAAGCATTAAGACACTTCCAGAATATTATGGACGTATTA
TAAAAGATGAGTTAAATATAAAGGATATTATATTTGGAGCAGACTTATCTAGTTATGTTGAATTTAATATAAAACCAAAC
CTACCAGTGCTGGGTAAAGCTTATGGAAGATATATTCCTCAAATAAGAAAAGAAATTACTTCCATGGATCAAATGAAATT
AGCTCAAAAGATAAAACAAGGAGAAAAAGTTATTATAAATATAGATGGAAATGAAATAGAATTAAATGAAGAAAATCTAC
TTGTAACAATGAAAGGGCTAGAAGGATTTGCTTTTGCAGGTGAAGGTAATATTGGTGTAGTTCTAAATACAACTATAACT
GACGAATTAAAAGAAGAAGGACAATTAAGAGAAATTTTAAGCAAGATACAAAATATGAGAAAAGAAAAAGAGTTTGAAGT
TGCAGATAGAATTAAACTATACGTATCTGGAAATAGGATGTTAGAAAGTGTTGTAGAAAAATTTGAGGATATTATAAGAA
AAGAAACTATTGCAGAAGAAGTTATATATAACGAAGAGAGAGAATATGTTGATTGTAAAATAAATGGAGAAGATTTCAAA
ATAGAAGTAGAAGCTATAAAATAA

Upstream 100 bases:

>100_bases
GGTGGTATAGCGAAGATAGACTTCGTCCTATTTGGACGAAGTCTTTTATATTATGAGAAAATAGTTTTTATGTAAATTTA
CTGACTATTATAATAAGTAT

Downstream 100 bases:

>100_bases
TAATATTTAAAGGACATTAGATATATTTAATGTCCTTTATTTAAATTATTTATATAAGTAGAAGTCTACTTTATAAATAA
TTTAAAATGCTGAAAAGGTT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS [H]

Number of amino acids: Translated: 1047; Mature: 1046

Protein sequence:

>1047_residues
MTRIVLGGSCKMYKKIDGSKSFVQMEREVLDFWNKNNIVDKSFALNEEGEYFTFYDGPPTANGKPHVGHVLTRVIKDLIP
RYKVMKGYKVLRKAGWDTHGLPVELEIEKKLGISGKEEIEKFGVEEFIKECKDSVFTYSSMWKDMSEKLAFWVDMENPYV
TYHNDYIESVWWALKQLWNKELLYKGHKVIPYCPRCGTALSSHEVAQGYKDVKEATAFVKFKVKGEENKYILAWTTTPWT
LPSNVALAINKNFDYVEVKNNDEVLILAKELVDSVIDGEYEIIKEFKGEDILGLQYEQLLPFYTPEEEAFRVIHGDFVTL
SDGTGIVHTAPAYGEDDNIVCKKHGLPMINLVDKEGKFIDCVEPWKGMPVKKADSKIIEYMDEKGILYKSEKFTHSYPHC
WRCDTALLYYPTDSWFVRMTSLRDKLLENNNKVNWYPDNIRTGRFGKFLENVIDWGISRDRYWGTPLPIWECECGHRECI
GSISELKEKGIDVPEDIELHKPYIDKVKLKCSKCGKEMKRTREVIDCWFDSGSMPFAQHHYPFENKEVFEKTFPAQFISE
AVDQTRGWFYTLTAISTAIFDTNPFENCIVLGHVLDKHGLKMSKSKGNVVDPFDVLDSAGADASRWHFYTASAPWLPTRF
SPEDVEETQRKFLSTLWNVYSFYVLYADIDKFNPLEYKDFVSENVMDKWIVSKLNSLIKDVEDHMDSYRITQAALAIEDF
VDELSNWYVRRNRSRFWSEELREDKIGAYVTLYKVLTTVSLIAAPFVPFITEEIYNNLVRGLDKNALESIHLCNWPKYDE
NLIQKELEREMDEAYKIVKLGRSARNSVNIKNRQPLSSMLVSIKTLPEYYGRIIKDELNIKDIIFGADLSSYVEFNIKPN
LPVLGKAYGRYIPQIRKEITSMDQMKLAQKIKQGEKVIINIDGNEIELNEENLLVTMKGLEGFAFAGEGNIGVVLNTTIT
DELKEEGQLREILSKIQNMRKEKEFEVADRIKLYVSGNRMLESVVEKFEDIIRKETIAEEVIYNEEREYVDCKINGEDFK
IEVEAIK

Sequences:

>Translated_1047_residues
MTRIVLGGSCKMYKKIDGSKSFVQMEREVLDFWNKNNIVDKSFALNEEGEYFTFYDGPPTANGKPHVGHVLTRVIKDLIP
RYKVMKGYKVLRKAGWDTHGLPVELEIEKKLGISGKEEIEKFGVEEFIKECKDSVFTYSSMWKDMSEKLAFWVDMENPYV
TYHNDYIESVWWALKQLWNKELLYKGHKVIPYCPRCGTALSSHEVAQGYKDVKEATAFVKFKVKGEENKYILAWTTTPWT
LPSNVALAINKNFDYVEVKNNDEVLILAKELVDSVIDGEYEIIKEFKGEDILGLQYEQLLPFYTPEEEAFRVIHGDFVTL
SDGTGIVHTAPAYGEDDNIVCKKHGLPMINLVDKEGKFIDCVEPWKGMPVKKADSKIIEYMDEKGILYKSEKFTHSYPHC
WRCDTALLYYPTDSWFVRMTSLRDKLLENNNKVNWYPDNIRTGRFGKFLENVIDWGISRDRYWGTPLPIWECECGHRECI
GSISELKEKGIDVPEDIELHKPYIDKVKLKCSKCGKEMKRTREVIDCWFDSGSMPFAQHHYPFENKEVFEKTFPAQFISE
AVDQTRGWFYTLTAISTAIFDTNPFENCIVLGHVLDKHGLKMSKSKGNVVDPFDVLDSAGADASRWHFYTASAPWLPTRF
SPEDVEETQRKFLSTLWNVYSFYVLYADIDKFNPLEYKDFVSENVMDKWIVSKLNSLIKDVEDHMDSYRITQAALAIEDF
VDELSNWYVRRNRSRFWSEELREDKIGAYVTLYKVLTTVSLIAAPFVPFITEEIYNNLVRGLDKNALESIHLCNWPKYDE
NLIQKELEREMDEAYKIVKLGRSARNSVNIKNRQPLSSMLVSIKTLPEYYGRIIKDELNIKDIIFGADLSSYVEFNIKPN
LPVLGKAYGRYIPQIRKEITSMDQMKLAQKIKQGEKVIINIDGNEIELNEENLLVTMKGLEGFAFAGEGNIGVVLNTTIT
DELKEEGQLREILSKIQNMRKEKEFEVADRIKLYVSGNRMLESVVEKFEDIIRKETIAEEVIYNEEREYVDCKINGEDFK
IEVEAIK
>Mature_1046_residues
TRIVLGGSCKMYKKIDGSKSFVQMEREVLDFWNKNNIVDKSFALNEEGEYFTFYDGPPTANGKPHVGHVLTRVIKDLIPR
YKVMKGYKVLRKAGWDTHGLPVELEIEKKLGISGKEEIEKFGVEEFIKECKDSVFTYSSMWKDMSEKLAFWVDMENPYVT
YHNDYIESVWWALKQLWNKELLYKGHKVIPYCPRCGTALSSHEVAQGYKDVKEATAFVKFKVKGEENKYILAWTTTPWTL
PSNVALAINKNFDYVEVKNNDEVLILAKELVDSVIDGEYEIIKEFKGEDILGLQYEQLLPFYTPEEEAFRVIHGDFVTLS
DGTGIVHTAPAYGEDDNIVCKKHGLPMINLVDKEGKFIDCVEPWKGMPVKKADSKIIEYMDEKGILYKSEKFTHSYPHCW
RCDTALLYYPTDSWFVRMTSLRDKLLENNNKVNWYPDNIRTGRFGKFLENVIDWGISRDRYWGTPLPIWECECGHRECIG
SISELKEKGIDVPEDIELHKPYIDKVKLKCSKCGKEMKRTREVIDCWFDSGSMPFAQHHYPFENKEVFEKTFPAQFISEA
VDQTRGWFYTLTAISTAIFDTNPFENCIVLGHVLDKHGLKMSKSKGNVVDPFDVLDSAGADASRWHFYTASAPWLPTRFS
PEDVEETQRKFLSTLWNVYSFYVLYADIDKFNPLEYKDFVSENVMDKWIVSKLNSLIKDVEDHMDSYRITQAALAIEDFV
DELSNWYVRRNRSRFWSEELREDKIGAYVTLYKVLTTVSLIAAPFVPFITEEIYNNLVRGLDKNALESIHLCNWPKYDEN
LIQKELEREMDEAYKIVKLGRSARNSVNIKNRQPLSSMLVSIKTLPEYYGRIIKDELNIKDIIFGADLSSYVEFNIKPNL
PVLGKAYGRYIPQIRKEITSMDQMKLAQKIKQGEKVIINIDGNEIELNEENLLVTMKGLEGFAFAGEGNIGVVLNTTITD
ELKEEGQLREILSKIQNMRKEKEFEVADRIKLYVSGNRMLESVVEKFEDIIRKETIAEEVIYNEEREYVDCKINGEDFKI
EVEAIK

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI94721239, Length=1050, Percent_Identity=37.9047619047619, Blast_Score=693, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1050, Percent_Identity=37.9047619047619, Blast_Score=693, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=772, Percent_Identity=28.2383419689119, Blast_Score=275, Evalue=2e-73,
Organism=Homo sapiens, GI268370293, Length=854, Percent_Identity=22.4824355971897, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI268370297, Length=854, Percent_Identity=22.4824355971897, Blast_Score=176, Evalue=2e-43,
Organism=Homo sapiens, GI268370295, Length=845, Percent_Identity=22.3668639053254, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI5454158, Length=808, Percent_Identity=21.1633663366337, Blast_Score=144, Evalue=4e-34,
Organism=Escherichia coli, GI2367096, Length=896, Percent_Identity=28.4598214285714, Blast_Score=327, Evalue=2e-90,
Organism=Escherichia coli, GI1790708, Length=869, Percent_Identity=22.7848101265823, Blast_Score=186, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17541896, Length=1031, Percent_Identity=36.6634335596508, Blast_Score=660, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=885, Percent_Identity=25.3107344632768, Blast_Score=246, Evalue=5e-65,
Organism=Caenorhabditis elegans, GI17510661, Length=842, Percent_Identity=22.4465558194774, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI72001587, Length=874, Percent_Identity=22.4256292906178, Blast_Score=181, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1036, Percent_Identity=37.0656370656371, Blast_Score=703, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=852, Percent_Identity=27.2300469483568, Blast_Score=296, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6321531, Length=871, Percent_Identity=23.3065442020666, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28574730, Length=1076, Percent_Identity=35.5018587360595, Blast_Score=649, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1076, Percent_Identity=35.5018587360595, Blast_Score=649, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1076, Percent_Identity=35.5018587360595, Blast_Score=649, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=782, Percent_Identity=26.0869565217391, Blast_Score=244, Evalue=2e-64,
Organism=Drosophila melanogaster, GI17864482, Length=861, Percent_Identity=23.8095238095238, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24653289, Length=861, Percent_Identity=23.8095238095238, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21355675, Length=804, Percent_Identity=21.6417910447761, Blast_Score=155, Evalue=2e-37,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 121469; Mature: 121338

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIVLGGSCKMYKKIDGSKSFVQMEREVLDFWNKNNIVDKSFALNEEGEYFTFYDGPPT
CCEEEECCCCEEEHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEECCCCC
ANGKPHVGHVLTRVIKDLIPRYKVMKGYKVLRKAGWDTHGLPVELEIEKKLGISGKEEIE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCCHHHHH
KFGVEEFIKECKDSVFTYSSMWKDMSEKLAFWVDMENPYVTYHNDYIESVWWALKQLWNK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEECHHHHHHHHHHHHHHHCH
ELLYKGHKVIPYCPRCGTALSSHEVAQGYKDVKEATAFVKFKVKGEENKYILAWTTTPWT
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEEECCCCC
LPSNVALAINKNFDYVEVKNNDEVLILAKELVDSVIDGEYEIIKEFKGEDILGLQYEQLL
CCCCEEEEEECCCCEEEECCCCCEEEEHHHHHHHHHCCHHHHHHHHCCCCEECCCHHHHC
PFYTPEEEAFRVIHGDFVTLSDGTGIVHTAPAYGEDDNIVCKKHGLPMINLVDKEGKFID
CCCCCHHHHHEEEECCEEEECCCCCEEEECCCCCCCCCEEEECCCCCEEEEECCCCCEEE
CVEPWKGMPVKKADSKIIEYMDEKGILYKSEKFTHSYPHCWRCDTALLYYPTDSWFVRMT
CCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCEECCCEEEEECCCCCEEEHH
SLRDKLLENNNKVNWYPDNIRTGRFGKFLENVIDWGISRDRYWGTPLPIWECECGHRECI
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHH
GSISELKEKGIDVPEDIELHKPYIDKVKLKCSKCGKEMKRTREVIDCWFDSGSMPFAQHH
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCC
YPFENKEVFEKTFPAQFISEAVDQTRGWFYTLTAISTAIFDTNPFENCIVLGHVLDKHGL
CCCCCHHHHHHHCCHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCHHEEHHHHHHHCCC
KMSKSKGNVVDPFDVLDSAGADASRWHFYTASAPWLPTRFSPEDVEETQRKFLSTLWNVY
EECCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SFYVLYADIDKFNPLEYKDFVSENVMDKWIVSKLNSLIKDVEDHMDSYRITQAALAIEDF
HHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDELSNWYVRRNRSRFWSEELREDKIGAYVTLYKVLTTVSLIAAPFVPFITEEIYNNLVR
HHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLDKNALESIHLCNWPKYDENLIQKELEREMDEAYKIVKLGRSARNSVNIKNRQPLSSML
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
VSIKTLPEYYGRIIKDELNIKDIIFGADLSSYVEFNIKPNLPVLGKAYGRYIPQIRKEIT
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHH
SMDQMKLAQKIKQGEKVIINIDGNEIELNEENLLVTMKGLEGFAFAGEGNIGVVLNTTIT
HHHHHHHHHHHCCCCEEEEEECCCEEEECCCCEEEEEECCCCEEEECCCCEEEEEECCHH
DELKEEGQLREILSKIQNMRKEKEFEVADRIKLYVSGNRMLESVVEKFEDIIRKETIAEE
HHHHHCCHHHHHHHHHHHHHHHHHHCHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
VIYNEEREYVDCKINGEDFKIEVEAIK
HHHCCCCCEEEEEECCCEEEEEEEEEC
>Mature Secondary Structure 
TRIVLGGSCKMYKKIDGSKSFVQMEREVLDFWNKNNIVDKSFALNEEGEYFTFYDGPPT
CEEEECCCCEEEHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEECCCCC
ANGKPHVGHVLTRVIKDLIPRYKVMKGYKVLRKAGWDTHGLPVELEIEKKLGISGKEEIE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCCHHHHH
KFGVEEFIKECKDSVFTYSSMWKDMSEKLAFWVDMENPYVTYHNDYIESVWWALKQLWNK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEECHHHHHHHHHHHHHHHCH
ELLYKGHKVIPYCPRCGTALSSHEVAQGYKDVKEATAFVKFKVKGEENKYILAWTTTPWT
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEEECCCCC
LPSNVALAINKNFDYVEVKNNDEVLILAKELVDSVIDGEYEIIKEFKGEDILGLQYEQLL
CCCCEEEEEECCCCEEEECCCCCEEEEHHHHHHHHHCCHHHHHHHHCCCCEECCCHHHHC
PFYTPEEEAFRVIHGDFVTLSDGTGIVHTAPAYGEDDNIVCKKHGLPMINLVDKEGKFID
CCCCCHHHHHEEEECCEEEECCCCCEEEECCCCCCCCCEEEECCCCCEEEEECCCCCEEE
CVEPWKGMPVKKADSKIIEYMDEKGILYKSEKFTHSYPHCWRCDTALLYYPTDSWFVRMT
CCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCEECCCEEEEECCCCCEEEHH
SLRDKLLENNNKVNWYPDNIRTGRFGKFLENVIDWGISRDRYWGTPLPIWECECGHRECI
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHH
GSISELKEKGIDVPEDIELHKPYIDKVKLKCSKCGKEMKRTREVIDCWFDSGSMPFAQHH
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCC
YPFENKEVFEKTFPAQFISEAVDQTRGWFYTLTAISTAIFDTNPFENCIVLGHVLDKHGL
CCCCCHHHHHHHCCHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCHHEEHHHHHHHCCC
KMSKSKGNVVDPFDVLDSAGADASRWHFYTASAPWLPTRFSPEDVEETQRKFLSTLWNVY
EECCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SFYVLYADIDKFNPLEYKDFVSENVMDKWIVSKLNSLIKDVEDHMDSYRITQAALAIEDF
HHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDELSNWYVRRNRSRFWSEELREDKIGAYVTLYKVLTTVSLIAAPFVPFITEEIYNNLVR
HHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLDKNALESIHLCNWPKYDENLIQKELEREMDEAYKIVKLGRSARNSVNIKNRQPLSSML
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
VSIKTLPEYYGRIIKDELNIKDIIFGADLSSYVEFNIKPNLPVLGKAYGRYIPQIRKEIT
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHH
SMDQMKLAQKIKQGEKVIINIDGNEIELNEENLLVTMKGLEGFAFAGEGNIGVVLNTTIT
HHHHHHHHHHHCCCCEEEEEECCCEEEECCCCEEEEEECCCCEEEECCCCEEEEEECCHH
DELKEEGQLREILSKIQNMRKEKEFEVADRIKLYVSGNRMLESVVEKFEDIIRKETIAEE
HHHHHCCHHHHHHHHHHHHHHHHHHCHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
VIYNEEREYVDCKINGEDFKIEVEAIK
HHHCCCCCEEEEEECCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]