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The map label for this gene is regA [H]

Identifier: 28210026

GI number: 28210026

Start: 234852

End: 235850

Strand: Direct

Name: regA [H]

Synonym: CTC00263

Alternate gene names: 28210026

Gene position: 234852-235850 (Clockwise)

Preceding gene: 28210025

Following gene: 28210027

Centisome position: 8.39

GC content: 27.83

Gene sequence:

>999_bases
ATGCCAGCATCAATAAAAGATGTAGCAAAAGAAGCTGGAGTATCTATAGCTACAGTATCCAGAGTATTAAATGATATAGA
TGTAGTTAATGAAGATACTAAAAAGAAAGTTTTAGATGCAATAAAAAAATTAGGTTATAGACCTAATATAGTGGCAAGAA
GTCTTAAAACTCAACGAACAAGTACAATAGGAATAATAGTGCCGGATATTTCTAATCAATTTTATCCTGAGATAGTAAGA
GGAGCTGAAGATGTAGCTAATATATATGAATATAATATAATGTTATGTAATACAGATTTAGATACAGAAAAAGAAAAAGA
ATATTTAAGAGTTTTAAAAGAAAAAATGACAGATGGAGTTCTTTATATGAGTAATTCTTTAGAAAATGAAACTGTAGAAT
TAATAAAAGAATTAAGAATTCCTACAGTGTTGGTGGAAACAACAGATGAAAATAAAGAATTTCCAAGTGTAAGTATAGAT
AACAAAAAAGCTGCATATGAAGCAGTTAAATATCTAATAAATAAAGGAAATAAAAAGATTGCCTATATAGGACCTAAAGA
TGAGAAAAACAATGCTGTTGCACTTAGATATAAAGGATATAAAAAATGTCTAGAAGAAAATAACATAGAAATAAAAGAGT
GTTTAATTTATAGGTCTGGATTGAAAGCAGGAGATGGATATGAAGCTATGGAAAAGATACTTAAAGAAGAATCCATAGAT
AGTGTGTTCTGTGCTAATGATGAAATTGCTATGGGAGCTATAAATGCCCTAAGAGATAAGGGGATAAATGTACCTGAAGA
TGTAGATGTAATTGGTTTTAATAATATATATTCAGCATCTATTTTTTATCCTAAACTTACAACTATATCTCAACCTATGT
ATGATATGGGATCTGTAGGAATGAGAATGCTTATAAAAACTATAAACAAAGAGCCATTAGAAAAGGAACATTATGTATTA
AATTATAATCTTATAGAAAGAGATTCTTGTAAAAAGTAA

Upstream 100 bases:

>100_bases
AAAAGGTTTGCTATTTTTTAGGCTATATCGTAAAATATAATTAGAAAAGAATGTAGTTTAAATAGAAAATAAAAGAAAAA
CTGTATTAGGAGTTGATAAT

Downstream 100 bases:

>100_bases
CAAGAATTTGTTAAGAACTATAACAAGATGAAAAAACACGGCAAAAGCTGTGTTTTTTTTATGTCATGTAAAAGAAAATA
ATGTTATACGAAAACTTTGA

Product: catabolite control protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPASIKDVAKEAGVSIATVSRVLNDIDVVNEDTKKKVLDAIKKLGYRPNIVARSLKTQRTSTIGIIVPDISNQFYPEIVR
GAEDVANIYEYNIMLCNTDLDTEKEKEYLRVLKEKMTDGVLYMSNSLENETVELIKELRIPTVLVETTDENKEFPSVSID
NKKAAYEAVKYLINKGNKKIAYIGPKDEKNNAVALRYKGYKKCLEENNIEIKECLIYRSGLKAGDGYEAMEKILKEESID
SVFCANDEIAMGAINALRDKGINVPEDVDVIGFNNIYSASIFYPKLTTISQPMYDMGSVGMRMLIKTINKEPLEKEHYVL
NYNLIERDSCKK

Sequences:

>Translated_332_residues
MPASIKDVAKEAGVSIATVSRVLNDIDVVNEDTKKKVLDAIKKLGYRPNIVARSLKTQRTSTIGIIVPDISNQFYPEIVR
GAEDVANIYEYNIMLCNTDLDTEKEKEYLRVLKEKMTDGVLYMSNSLENETVELIKELRIPTVLVETTDENKEFPSVSID
NKKAAYEAVKYLINKGNKKIAYIGPKDEKNNAVALRYKGYKKCLEENNIEIKECLIYRSGLKAGDGYEAMEKILKEESID
SVFCANDEIAMGAINALRDKGINVPEDVDVIGFNNIYSASIFYPKLTTISQPMYDMGSVGMRMLIKTINKEPLEKEHYVL
NYNLIERDSCKK
>Mature_331_residues
PASIKDVAKEAGVSIATVSRVLNDIDVVNEDTKKKVLDAIKKLGYRPNIVARSLKTQRTSTIGIIVPDISNQFYPEIVRG
AEDVANIYEYNIMLCNTDLDTEKEKEYLRVLKEKMTDGVLYMSNSLENETVELIKELRIPTVLVETTDENKEFPSVSIDN
KKAAYEAVKYLINKGNKKIAYIGPKDEKNNAVALRYKGYKKCLEENNIEIKECLIYRSGLKAGDGYEAMEKILKEESIDS
VFCANDEIAMGAINALRDKGINVPEDVDVIGFNNIYSASIFYPKLTTISQPMYDMGSVGMRMLIKTINKEPLEKEHYVLN
YNLIERDSCKK

Specific function: Involved in the regulation of amylase production [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=36.0606060606061, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1790369, Length=332, Percent_Identity=33.7349397590361, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1790194, Length=331, Percent_Identity=33.8368580060423, Blast_Score=187, Evalue=8e-49,
Organism=Escherichia coli, GI1788474, Length=332, Percent_Identity=31.0240963855422, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789202, Length=329, Percent_Identity=29.1793313069909, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789068, Length=300, Percent_Identity=30.3333333333333, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI48994940, Length=323, Percent_Identity=28.1733746130031, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1790715, Length=308, Percent_Identity=28.5714285714286, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1789456, Length=328, Percent_Identity=28.6585365853659, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787580, Length=319, Percent_Identity=25.705329153605, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786540, Length=333, Percent_Identity=26.1261261261261, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787906, Length=320, Percent_Identity=25.9375, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790689, Length=288, Percent_Identity=25, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1786268, Length=277, Percent_Identity=22.0216606498195, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37530; Mature: 37398

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASIKDVAKEAGVSIATVSRVLNDIDVVNEDTKKKVLDAIKKLGYRPNIVARSLKTQRT
CCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
STIGIIVPDISNQFYPEIVRGAEDVANIYEYNIMLCNTDLDTEKEKEYLRVLKEKMTDGV
CEEEEEECCCCCCHHHHHHHCHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCE
LYMSNSLENETVELIKELRIPTVLVETTDENKEFPSVSIDNKKAAYEAVKYLINKGNKKI
EEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
AYIGPKDEKNNAVALRYKGYKKCLEENNIEIKECLIYRSGLKAGDGYEAMEKILKEESID
EEECCCCCCCCEEEEEECHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
SVFCANDEIAMGAINALRDKGINVPEDVDVIGFNNIYSASIFYPKLTTISQPMYDMGSVG
CEEECCCCHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCHHHHCCCHHHHHHHH
MRMLIKTINKEPLEKEHYVLNYNLIERDSCKK
HHHHHHHHCCCCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure 
PASIKDVAKEAGVSIATVSRVLNDIDVVNEDTKKKVLDAIKKLGYRPNIVARSLKTQRT
CCCHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
STIGIIVPDISNQFYPEIVRGAEDVANIYEYNIMLCNTDLDTEKEKEYLRVLKEKMTDGV
CEEEEEECCCCCCHHHHHHHCHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCE
LYMSNSLENETVELIKELRIPTVLVETTDENKEFPSVSIDNKKAAYEAVKYLINKGNKKI
EEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
AYIGPKDEKNNAVALRYKGYKKCLEENNIEIKECLIYRSGLKAGDGYEAMEKILKEESID
EEECCCCCCCCEEEEEECHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
SVFCANDEIAMGAINALRDKGINVPEDVDVIGFNNIYSASIFYPKLTTISQPMYDMGSVG
CEEECCCCHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCHHHHCCCHHHHHHHH
MRMLIKTINKEPLEKEHYVLNYNLIERDSCKK
HHHHHHHHCCCCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]