Click here to switch to the map view.

The map label for this gene is tatD [H]

Identifier: 28210010

GI number: 28210010

Start: 213496

End: 214269

Strand: Direct

Name: tatD [H]

Synonym: CTC00244

Alternate gene names: 28210010

Gene position: 213496-214269 (Clockwise)

Preceding gene: 28210009

Following gene: 28210011

Centisome position: 7.63

GC content: 29.2

Gene sequence:

>774_bases
ATGAAAATGAAAATATTTGATTCACATGCTCATTATGATGATGATTCATTTAATGAAGATAGAATAAAGGTTTTAGAAGA
ACTAAAAAATAATAATATTATTGGAGTGTTAAATTGTGGTTCTTCCTTTAAAGGAGCTGTAGATTCATTAAATTTAGCTA
AGAATAATGATTTCTTTTATGCTGCTGTAGGAATTCATCCTGAATATGCTGATACGGTAGATGAAGATATGTTAAATGAA
ATAAAAAATATGACTTCTTATCCTAAAGTAAAAGCTATTGGGGAAATAGGACTAGATTATTACTATGAAGATAATCCACC
GAAGGAGGTTCAAAAAGAAGCATTTATAAAGCAAATGAAATTAGCAAAAGAATTAAATTTGCCTGTGGTAATTCATGACA
GAGATGCTCATAAAGACATTTTAGATATAATAAAAATGTTCCCAGAAGTATATGGGGTAATCCATTGTTTCTCGGGAAGT
GTAGAATTTGCAAGAGAATGCTTAAAATTGGGTTACTATATAGGATTTACAGGTGTTGTAACCTTTAAGAATGCTAGGAA
AACTTTAGAGGTAGCAAAAGAGGTTCCTATAGATAAGATATTAGTTGAAACGGATTGCCCATATATGGCACCGGAGCCCC
ATAGAGGAAAACGAAATAGATCAGAGTATATAGAACAGATTATCAAAAAAATAGCTAAAATTAAAGAAATATCAGAAGAA
GAGCTTAATAATCAAGTAATATTAAATACAAAACATTTGCTTAATATAAAATAA

Upstream 100 bases:

>100_bases
ACGGAAATATATTTTTAATATAATATGAATAAAAAATAATTATATGGTAATATTATGTAATAAATCTCTTTTACCATAAG
TTATAAAGGTTGAAAGGAAA

Downstream 100 bases:

>100_bases
TAATATAAAATATACGTAGTATTTTTTATGCTACAAACATATAATTAATTAAAACAAAGAACATATAGCAAATAAAGGGT
AATAACATTTTAAATATAGA

Product: deoxyribonuclease tatD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKMKIFDSHAHYDDDSFNEDRIKVLEELKNNNIIGVLNCGSSFKGAVDSLNLAKNNDFFYAAVGIHPEYADTVDEDMLNE
IKNMTSYPKVKAIGEIGLDYYYEDNPPKEVQKEAFIKQMKLAKELNLPVVIHDRDAHKDILDIIKMFPEVYGVIHCFSGS
VEFARECLKLGYYIGFTGVVTFKNARKTLEVAKEVPIDKILVETDCPYMAPEPHRGKRNRSEYIEQIIKKIAKIKEISEE
ELNNQVILNTKHLLNIK

Sequences:

>Translated_257_residues
MKMKIFDSHAHYDDDSFNEDRIKVLEELKNNNIIGVLNCGSSFKGAVDSLNLAKNNDFFYAAVGIHPEYADTVDEDMLNE
IKNMTSYPKVKAIGEIGLDYYYEDNPPKEVQKEAFIKQMKLAKELNLPVVIHDRDAHKDILDIIKMFPEVYGVIHCFSGS
VEFARECLKLGYYIGFTGVVTFKNARKTLEVAKEVPIDKILVETDCPYMAPEPHRGKRNRSEYIEQIIKKIAKIKEISEE
ELNNQVILNTKHLLNIK
>Mature_257_residues
MKMKIFDSHAHYDDDSFNEDRIKVLEELKNNNIIGVLNCGSSFKGAVDSLNLAKNNDFFYAAVGIHPEYADTVDEDMLNE
IKNMTSYPKVKAIGEIGLDYYYEDNPPKEVQKEAFIKQMKLAKELNLPVVIHDRDAHKDILDIIKMFPEVYGVIHCFSGS
VEFARECLKLGYYIGFTGVVTFKNARKTLEVAKEVPIDKILVETDCPYMAPEPHRGKRNRSEYIEQIIKKIAKIKEISEE
ELNNQVILNTKHLLNIK

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=159, Percent_Identity=37.7358490566038, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI225903439, Length=241, Percent_Identity=31.5352697095436, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI14042943, Length=241, Percent_Identity=31.5352697095436, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI110349730, Length=250, Percent_Identity=27.2, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI110349734, Length=250, Percent_Identity=27.2, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI226061853, Length=255, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI226061595, Length=225, Percent_Identity=25.7777777777778, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI226061614, Length=242, Percent_Identity=25.6198347107438, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI1787342, Length=260, Percent_Identity=35.3846153846154, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI87082439, Length=262, Percent_Identity=30.9160305343511, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI48994985, Length=262, Percent_Identity=29.3893129770992, Blast_Score=131, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17559024, Length=215, Percent_Identity=33.4883720930233, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17565396, Length=234, Percent_Identity=30.3418803418803, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17543026, Length=224, Percent_Identity=29.0178571428571, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71980746, Length=246, Percent_Identity=25.2032520325203, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI221330018, Length=302, Percent_Identity=29.8013245033113, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24586117, Length=269, Percent_Identity=30.4832713754647, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24648690, Length=223, Percent_Identity=30.4932735426009, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29506; Mature: 29506

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMKIFDSHAHYDDDSFNEDRIKVLEELKNNNIIGVLNCGSSFKGAVDSLNLAKNNDFFY
CCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCEEECCCCEEE
AAVGIHPEYADTVDEDMLNEIKNMTSYPKVKAIGEIGLDYYYEDNPPKEVQKEAFIKQMK
EEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHH
LAKELNLPVVIHDRDAHKDILDIIKMFPEVYGVIHCFSGSVEFARECLKLGYYIGFTGVV
HHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEE
TFKNARKTLEVAKEVPIDKILVETDCPYMAPEPHRGKRNRSEYIEQIIKKIAKIKEISEE
EEHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ELNNQVILNTKHLLNIK
HCCCEEEEECHHEEECC
>Mature Secondary Structure
MKMKIFDSHAHYDDDSFNEDRIKVLEELKNNNIIGVLNCGSSFKGAVDSLNLAKNNDFFY
CCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCEEECCCCEEE
AAVGIHPEYADTVDEDMLNEIKNMTSYPKVKAIGEIGLDYYYEDNPPKEVQKEAFIKQMK
EEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHH
LAKELNLPVVIHDRDAHKDILDIIKMFPEVYGVIHCFSGSVEFARECLKLGYYIGFTGVV
HHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEE
TFKNARKTLEVAKEVPIDKILVETDCPYMAPEPHRGKRNRSEYIEQIIKKIAKIKEISEE
EEHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ELNNQVILNTKHLLNIK
HCCCEEEEECHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]