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The map label for this gene is ctpA [H]

Identifier: 28199918

GI number: 28199918

Start: 2427287

End: 2428708

Strand: Reverse

Name: ctpA [H]

Synonym: PD2057

Alternate gene names: 28199918

Gene position: 2428708-2427287 (Counterclockwise)

Preceding gene: 28199919

Following gene: 28199917

Centisome position: 96.38

GC content: 53.23

Gene sequence:

>1422_bases
GTGGTCTTGTTGTCTTTCTCGTTGTCGGCGAAGAATCCCAGCGGTGTTGTTATGTCTCCTCCGGTTGAAGAGATGGAAAT
GCCGGAGAGCAACGATGTTAACGTGCCGTTAGATGAAATCCGCCGCTTTGTTTCTGTGTATAACGCCATCAAGCAAGCCT
ATGTTGATCCGGTCAATGACAGGAAGCTGATGCATTCTGCGGTGCGAGGTCTGCTTTCGGATCTGGATCCGCATAGTACC
TATTTTGATAAGGAGGATGCCGATGCCTTCGACGAGCAAACCAGCGGTGTTTACGATGGGATCGGTGTGGAGCTGCAAGA
GCAGTCGGACAACACGTTGAAGGTGATCGCGCCGATTGATGATACGCCAGCAGCGCGTGCTGGTTTGCGTCCAGGTGATC
TGATCGTGGCGATCAACGGCAAGCCGCTTGCCAATGTCGATGCGATGAAGCCGCTGCGCGGTGCGCCAGGCAGTCAAGTC
ACTTTGACGATTGTGCGCGATAAGAATGGCAAGCCATTCGATATGACAATCAAGCGTGAGACGATACACATCGCTAGTGT
GCGTAGCCGTATGCTTGAGCCTGGTTATGGCTATATCCGTATTAGTGTTTTCCAGGCCGATACGGGTAACGATTTCCATA
AGCATTTGGGACAGCTTAAGCAGCAAGCGGGTGGTAAGTTGCGTGGTCTGTTATTGGACTTGCGTAGTAATCCTGGTGGA
TTGCTGACGGCAGCGGTGCAGGTTGCTGATGCTTTGTTGGATAAGGGAAACATTGTCAGTACGCGTGGCCGTATTTCGGC
GAGTGATACGCGCTTTGATGCAACGCTGGGAGATTTACTGGATGGTCTCCCGTTGGTGGTATTGGTCGATGCTGGTTCGG
CCAGCGCTTCGGAGGTGTTGGTGGGTGCGCTGAGTGACAATCATCGTGCGCGCGTCATTGGCAGCTGTACCTTCGGTAAG
GGATCGGTGCAGACGTTGTTGCCGCTTGATAATGGCGATTCGGTCAAATTGACGACGGCGCGTTATTACACTCCGAGTGG
TCGTTCGATCCAAGCGAGGGGGATTGTTCCTGATCTGCTGCTCAAGCCAGATGGTGTTGGAGCGGCTGATCTTTCAGGCA
GCGGGATTGATCGCAGTGAGGCAGGGCTTCCAGGCCATTTGCGTGGTACTGATGAAGGGGTGCCAGGTTGTACTTCCAGT
GATCCGTTGCCGGGCGATACGCCGATCATGACGGCGTTGTTGGAGCTAAAGCAACCGGGTTCAGCGGTGCAGGCTAAAAA
AGCGATCCCTGTAAAAGTGGTCAGCGATGTTAAGTCGGCAACAAAGAGTCCGTTGTCAGTGTTTGGTAAGGATAGGGCTG
TCAAGCGAGTGCCGGTGGTGTCTCCTACAAGTGAGCAAGTTGATGGTCAGCCAAGCAAATAG

Upstream 100 bases:

>100_bases
TGTTGCTTCCCGCATAATTCGTCATTGCTCGGTAGTACCGGGTGCCGTTTTCTTTCCGGAGTGCTGCATGCGTGTTGTTG
GGTTGTCATTGGCCATAAGT

Downstream 100 bases:

>100_bases
CATGGTGTGCCGTATTGTTAGGGGGCTGTCTGTGGTTTTTTAAAAATGTTCGGATGATGTGTTGCATGTGGTTTTGTATG
AATGATGGTGTCCTGGGTGT

Product: carboxyl-terminal protease

Products: NA

Alternate protein names: C-terminal-processing protease [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MVLLSFSLSAKNPSGVVMSPPVEEMEMPESNDVNVPLDEIRRFVSVYNAIKQAYVDPVNDRKLMHSAVRGLLSDLDPHST
YFDKEDADAFDEQTSGVYDGIGVELQEQSDNTLKVIAPIDDTPAARAGLRPGDLIVAINGKPLANVDAMKPLRGAPGSQV
TLTIVRDKNGKPFDMTIKRETIHIASVRSRMLEPGYGYIRISVFQADTGNDFHKHLGQLKQQAGGKLRGLLLDLRSNPGG
LLTAAVQVADALLDKGNIVSTRGRISASDTRFDATLGDLLDGLPLVVLVDAGSASASEVLVGALSDNHRARVIGSCTFGK
GSVQTLLPLDNGDSVKLTTARYYTPSGRSIQARGIVPDLLLKPDGVGAADLSGSGIDRSEAGLPGHLRGTDEGVPGCTSS
DPLPGDTPIMTALLELKQPGSAVQAKKAIPVKVVSDVKSATKSPLSVFGKDRAVKRVPVVSPTSEQVDGQPSK

Sequences:

>Translated_473_residues
MVLLSFSLSAKNPSGVVMSPPVEEMEMPESNDVNVPLDEIRRFVSVYNAIKQAYVDPVNDRKLMHSAVRGLLSDLDPHST
YFDKEDADAFDEQTSGVYDGIGVELQEQSDNTLKVIAPIDDTPAARAGLRPGDLIVAINGKPLANVDAMKPLRGAPGSQV
TLTIVRDKNGKPFDMTIKRETIHIASVRSRMLEPGYGYIRISVFQADTGNDFHKHLGQLKQQAGGKLRGLLLDLRSNPGG
LLTAAVQVADALLDKGNIVSTRGRISASDTRFDATLGDLLDGLPLVVLVDAGSASASEVLVGALSDNHRARVIGSCTFGK
GSVQTLLPLDNGDSVKLTTARYYTPSGRSIQARGIVPDLLLKPDGVGAADLSGSGIDRSEAGLPGHLRGTDEGVPGCTSS
DPLPGDTPIMTALLELKQPGSAVQAKKAIPVKVVSDVKSATKSPLSVFGKDRAVKRVPVVSPTSEQVDGQPSK
>Mature_473_residues
MVLLSFSLSAKNPSGVVMSPPVEEMEMPESNDVNVPLDEIRRFVSVYNAIKQAYVDPVNDRKLMHSAVRGLLSDLDPHST
YFDKEDADAFDEQTSGVYDGIGVELQEQSDNTLKVIAPIDDTPAARAGLRPGDLIVAINGKPLANVDAMKPLRGAPGSQV
TLTIVRDKNGKPFDMTIKRETIHIASVRSRMLEPGYGYIRISVFQADTGNDFHKHLGQLKQQAGGKLRGLLLDLRSNPGG
LLTAAVQVADALLDKGNIVSTRGRISASDTRFDATLGDLLDGLPLVVLVDAGSASASEVLVGALSDNHRARVIGSCTFGK
GSVQTLLPLDNGDSVKLTTARYYTPSGRSIQARGIVPDLLLKPDGVGAADLSGSGIDRSEAGLPGHLRGTDEGVPGCTSS
DPLPGDTPIMTALLELKQPGSAVQAKKAIPVKVVSDVKSATKSPLSVFGKDRAVKRVPVVSPTSEQVDGQPSK

Specific function: Involved in protection of the bacterium from thermal and osmotic stresses (Potential) [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=331, Percent_Identity=31.1178247734139, Blast_Score=122, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 49994; Mature: 49994

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLLSFSLSAKNPSGVVMSPPVEEMEMPESNDVNVPLDEIRRFVSVYNAIKQAYVDPVND
CEEEEEEECCCCCCCEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCH
RKLMHSAVRGLLSDLDPHSTYFDKEDADAFDEQTSGVYDGIGVELQEQSDNTLKVIAPID
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCEEEEEECCC
DTPAARAGLRPGDLIVAINGKPLANVDAMKPLRGAPGSQVTLTIVRDKNGKPFDMTIKRE
CCCHHHCCCCCCCEEEEECCCCCCCCHHCCCCCCCCCCEEEEEEEECCCCCCEEEEEECC
TIHIASVRSRMLEPGYGYIRISVFQADTGNDFHKHLGQLKQQAGGKLRGLLLDLRSNPGG
EEEHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCH
LLTAAVQVADALLDKGNIVSTRGRISASDTRFDATLGDLLDGLPLVVLVDAGSASASEVL
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEE
VGALSDNHRARVIGSCTFGKGSVQTLLPLDNGDSVKLTTARYYTPSGRSIQARGIVPDLL
EEECCCCCCEEEEEEEECCCCCCEEEEECCCCCEEEEEEEEEECCCCCEEEECCCCHHHE
LKPDGVGAADLSGSGIDRSEAGLPGHLRGTDEGVPGCTSSDPLPGDTPIMTALLELKQPG
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
SAVQAKKAIPVKVVSDVKSATKSPLSVFGKDRAVKRVPVVSPTSEQVDGQPSK
CHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCEEECCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MVLLSFSLSAKNPSGVVMSPPVEEMEMPESNDVNVPLDEIRRFVSVYNAIKQAYVDPVND
CEEEEEEECCCCCCCEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCH
RKLMHSAVRGLLSDLDPHSTYFDKEDADAFDEQTSGVYDGIGVELQEQSDNTLKVIAPID
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCEEEEEECCC
DTPAARAGLRPGDLIVAINGKPLANVDAMKPLRGAPGSQVTLTIVRDKNGKPFDMTIKRE
CCCHHHCCCCCCCEEEEECCCCCCCCHHCCCCCCCCCCEEEEEEEECCCCCCEEEEEECC
TIHIASVRSRMLEPGYGYIRISVFQADTGNDFHKHLGQLKQQAGGKLRGLLLDLRSNPGG
EEEHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCH
LLTAAVQVADALLDKGNIVSTRGRISASDTRFDATLGDLLDGLPLVVLVDAGSASASEVL
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEE
VGALSDNHRARVIGSCTFGKGSVQTLLPLDNGDSVKLTTARYYTPSGRSIQARGIVPDLL
EEECCCCCCEEEEEEEECCCCCCEEEEECCCCCEEEEEEEEEECCCCCEEEECCCCHHHE
LKPDGVGAADLSGSGIDRSEAGLPGHLRGTDEGVPGCTSSDPLPGDTPIMTALLELKQPG
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
SAVQAKKAIPVKVVSDVKSATKSPLSVFGKDRAVKRVPVVSPTSEQVDGQPSK
CHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCEEECCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141685 [H]