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The map label for this gene is rlmM

Identifier: 28199774

GI number: 28199774

Start: 2236891

End: 2237946

Strand: Reverse

Name: rlmM

Synonym: PD1906

Alternate gene names: 28199774

Gene position: 2237946-2236891 (Counterclockwise)

Preceding gene: 28199776

Following gene: 77747717

Centisome position: 88.81

GC content: 55.87

Gene sequence:

>1056_bases
ATGAGCGGTTTAATCGCTTACTGCCGTCAAGGGTTTGAGCCGGAATTGGCGGCTGAATTGAGGGACCGCGCCGTATTACT
CGGAATCGCCAGTGATATACACGCACAGCGTAATCATGGCTTCGTACTCTTGCGGTGCGATCCCCTTCATGTCGATACAC
TGCTACAGCAATTGCACTGGCGCCGCTTGATCTTCGCGCGACAAACCCTGCGTTTACATGCCGAACTGAAAACACTCAAC
TCACGAGACCGCATTGCTCCCATCCTGGCAGCACTCCCCAAGACACCATGCTTTGGTGATTTGTGGATTGAGTACCCAGA
CTCAGACATGGGCAAGCCATTAGCTGGACTAGCCCGCAGTTTCGGCAACGCATTGCGTCCCGTACTGCGCAGTGCTGGTC
GACTTTCCGCGCAGCTCCATCCACAGTGGCCACGCCTGCACGTCTGCTTCCTGAGTGGTGACCACGTATTGCTAGGCAGC
ACACGTTCCGTTGACAGTGCGCCGTGGCAACTCGGCATCCCGCGTTTGAAACTGTTGCCAGAGGCTCCATCACGCTCTGC
ACTTAAGTTGGAAGAGGCATTGATCACCCTGCTCACTCCGAACGAGCGTGAAGCCAAATTACGCCCTGGCATGTGTGCGA
CCGACCTAGGCGCAGCGCCCGGTGGTTGGACTTGGGTATTGATTTGCCAGCATCTGCGCGTGACCAGCATTGACAATGCG
GCATTGCGGCCACCACTGCTCAATCATCCATTGGTCCAGCACGTGCGGGCCGATGGCTTTCGTTGGATACCGCCACGGCC
AATGGATTGGATGGTCTGCGACATGGTTGAACAGCCACGTCGGGTTGCAGAACGTATGGCTGTCTGGCTGCGTGAAGGGT
GGTGTCGGCACATGATCTTTAATCTCAAGCTACCGATGAAAAAACGTTGGGATGAAACCCGATTGTGTTTGGAACGCTTC
GAAACCCAGGCGGCAGTGCCACTGACCCTACGCGCCAAGCAGTTGTATCATGACCGCGAAGAGATCACCGTTTATGCCAG
CAACGACGCTCGGTAA

Upstream 100 bases:

>100_bases
ACCGCTTAAGCGCGAGATTGAGATTGAAGTCGTCCCTACCCCGTCACACCGCCCCATGCGTGTGCTGCTGCATCAGCACC
AACATGATGCAGGTGCGACG

Downstream 100 bases:

>100_bases
ATTTCTTCAATCACCCATTGATCACTTCATTCAGCATCACGCGACAGGCACATTGTATGGTTTTGGAACATCCTGTTTTT
ATGATTGCTGAATTTAAATA

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSGLIAYCRQGFEPELAAELRDRAVLLGIASDIHAQRNHGFVLLRCDPLHVDTLLQQLHWRRLIFARQTLRLHAELKTLN
SRDRIAPILAALPKTPCFGDLWIEYPDSDMGKPLAGLARSFGNALRPVLRSAGRLSAQLHPQWPRLHVCFLSGDHVLLGS
TRSVDSAPWQLGIPRLKLLPEAPSRSALKLEEALITLLTPNEREAKLRPGMCATDLGAAPGGWTWVLICQHLRVTSIDNA
ALRPPLLNHPLVQHVRADGFRWIPPRPMDWMVCDMVEQPRRVAERMAVWLREGWCRHMIFNLKLPMKKRWDETRLCLERF
ETQAAVPLTLRAKQLYHDREEITVYASNDAR

Sequences:

>Translated_351_residues
MSGLIAYCRQGFEPELAAELRDRAVLLGIASDIHAQRNHGFVLLRCDPLHVDTLLQQLHWRRLIFARQTLRLHAELKTLN
SRDRIAPILAALPKTPCFGDLWIEYPDSDMGKPLAGLARSFGNALRPVLRSAGRLSAQLHPQWPRLHVCFLSGDHVLLGS
TRSVDSAPWQLGIPRLKLLPEAPSRSALKLEEALITLLTPNEREAKLRPGMCATDLGAAPGGWTWVLICQHLRVTSIDNA
ALRPPLLNHPLVQHVRADGFRWIPPRPMDWMVCDMVEQPRRVAERMAVWLREGWCRHMIFNLKLPMKKRWDETRLCLERF
ETQAAVPLTLRAKQLYHDREEITVYASNDAR
>Mature_350_residues
SGLIAYCRQGFEPELAAELRDRAVLLGIASDIHAQRNHGFVLLRCDPLHVDTLLQQLHWRRLIFARQTLRLHAELKTLNS
RDRIAPILAALPKTPCFGDLWIEYPDSDMGKPLAGLARSFGNALRPVLRSAGRLSAQLHPQWPRLHVCFLSGDHVLLGST
RSVDSAPWQLGIPRLKLLPEAPSRSALKLEEALITLLTPNEREAKLRPGMCATDLGAAPGGWTWVLICQHLRVTSIDNAA
LRPPLLNHPLVQHVRADGFRWIPPRPMDWMVCDMVEQPRRVAERMAVWLREGWCRHMIFNLKLPMKKRWDETRLCLERFE
TQAAVPLTLRAKQLYHDREEITVYASNDAR

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily

Homologues:

Organism=Escherichia coli, GI1789171, Length=352, Percent_Identity=41.4772727272727, Blast_Score=257, Evalue=8e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMM_XYLF2 (B2I9N9)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830684.1
- ProteinModelPortal:   B2I9N9
- SMR:   B2I9N9
- GeneID:   6203366
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_2011
- HOGENOM:   HBG681972
- ProtClustDB:   PRK11760
- GO:   GO:0005737
- HAMAP:   MF_01551
- InterPro:   IPR011224
- InterPro:   IPR002877
- PIRSF:   PIRSF028774

Pfam domain/function: PF01728 FtsJ

EC number: NA

Molecular weight: Translated: 40041; Mature: 39910

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLIAYCRQGFEPELAAELRDRAVLLGIASDIHAQRNHGFVLLRCDPLHVDTLLQQLHW
CCCHHHHHHCCCCHHHHHHHHCCEEEEEEHHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
RRLIFARQTLRLHAELKTLNSRDRIAPILAALPKTPCFGDLWIEYPDSDMGKPLAGLARS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHH
FGNALRPVLRSAGRLSAQLHPQWPRLHVCFLSGDHVLLGSTRSVDSAPWQLGIPRLKLLP
HHHHHHHHHHHCCCCCEECCCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCEEECC
EAPSRSALKLEEALITLLTPNEREAKLRPGMCATDLGAAPGGWTWVLICQHLRVTSIDNA
CCCCCCHHHHHHHHHEEECCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCC
ALRPPLLNHPLVQHVRADGFRWIPPRPMDWMVCDMVEQPRRVAERMAVWLREGWCRHMIF
CCCCCCCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
NLKLPMKKRWDETRLCLERFETQAAVPLTLRAKQLYHDREEITVYASNDAR
ECCCCHHHCCCHHHHHHHHHHCCCCCCCEEHHHHHHCCCCCEEEEECCCCC
>Mature Secondary Structure 
SGLIAYCRQGFEPELAAELRDRAVLLGIASDIHAQRNHGFVLLRCDPLHVDTLLQQLHW
CCHHHHHHCCCCHHHHHHHHCCEEEEEEHHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
RRLIFARQTLRLHAELKTLNSRDRIAPILAALPKTPCFGDLWIEYPDSDMGKPLAGLARS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHH
FGNALRPVLRSAGRLSAQLHPQWPRLHVCFLSGDHVLLGSTRSVDSAPWQLGIPRLKLLP
HHHHHHHHHHHCCCCCEECCCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCEEECC
EAPSRSALKLEEALITLLTPNEREAKLRPGMCATDLGAAPGGWTWVLICQHLRVTSIDNA
CCCCCCHHHHHHHHHEEECCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCC
ALRPPLLNHPLVQHVRADGFRWIPPRPMDWMVCDMVEQPRRVAERMAVWLREGWCRHMIF
CCCCCCCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
NLKLPMKKRWDETRLCLERFETQAAVPLTLRAKQLYHDREEITVYASNDAR
ECCCCHHHCCCHHHHHHHHHHCCCCCCCEEHHHHHHCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA