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The map label for this gene is rfbB [C]

Identifier: 28199422

GI number: 28199422

Start: 1788835

End: 1789824

Strand: Reverse

Name: rfbB [C]

Synonym: PD1543

Alternate gene names: 28199422

Gene position: 1789824-1788835 (Counterclockwise)

Preceding gene: 28199423

Following gene: 28199421

Centisome position: 71.03

GC content: 48.28

Gene sequence:

>990_bases
TTGGTCGATCAAGCTTGGATTTTGAAGTGTTCTTATGGAGTACCCATGTCTGGAAATAACAACAGAGTGCTAGTCACCGG
GGGTGCTGGCTTTCTGGGATCCCATCTATGCGAGAAATTGGTTGCTTCCGGTCACGATGTATTATGTGTTGACAATTTTT
ATACGGGTAGCAAGGACAGTGTCATCAACCTGATTGGTCACCCTAAGTTTGAATTGATACGCCATGATGTCACCTTCCCA
CTCTATGTTGAAGTCGACCGCATTTACAATCTTGCTTGTCCGGCATCGCCAGTGCATTACCAGCATGATCCAGTGCAGAC
GACAAAAACCAGTGTGCATGGTGCAATCAACATGTTAGGGCTGGCCAAGCGGGTCAAGGCACGTATTCTTCAAGCCAGCA
CCAGTGAAGTGTACGGCGATCCAGAAATTCATCCACAACTCGAAACCTATTGGGGGCGTGTGAACCCGGTGGGCATCCGT
AGTTGCTATGACGAAGGGAAGCGTTGTGCGGAGACACTGTTTTTCGATTATTGGCGCCAGCACAAGTTAGAGATCAAGGT
CACGCGTATTTTTAATACCTATGGTCCGCGCATGCATCCCAATGATGGTCGGGTGGTGAGTAACTTCATTGTGCAGGCAC
TGCGTGGTGAGCCAATCACCATCTACGGGGATGGTACCCAAACGCGCAGCTTCTGCTACGTCGATGATCTGATTGATGGC
ATGTTGCGAATGATGGAAAGTCCCAAAGATTTTAATGGACCGGTAAACATTGGTAACCCCACTGAGTTTACGATGCTGCA
GCTGGCTGAAATGGTCCTTAAATTGGTGGGTAGTATTTCAAAAATCGTATTTCAACCGCTGCCCTTGGATGATCCGAAAC
AGCGTCAGCCGGATATCACTTTGGCTAAATCTCAACTTGGCTGGGAACCCAAGGTCTCGCTTGAAGATGGCCTCAGGGAA
ACCATTGCTTATTTCCGTAAGCGTGTTTAG

Upstream 100 bases:

>100_bases
ATTGATTGGCCCTTGGAGTTCTCCTCCATTGAGAGAAACATTGGAATGGATGCTCAAAACTGCTGTTTGATGGACGAGTC
GACTGAGAAGTTTATCTTCC

Downstream 100 bases:

>100_bases
CAATGTCTGCTTCAGTGCCTCCGCTTGTTATTGTGATACCGGTTTTTGAAGATATCGAAGCTTCAAGCCAGTTATTCCAG
GAACTTGCAAAAAATCAGAG

Product: dTDP-glucose 4-6-dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MVDQAWILKCSYGVPMSGNNNRVLVTGGAGFLGSHLCEKLVASGHDVLCVDNFYTGSKDSVINLIGHPKFELIRHDVTFP
LYVEVDRIYNLACPASPVHYQHDPVQTTKTSVHGAINMLGLAKRVKARILQASTSEVYGDPEIHPQLETYWGRVNPVGIR
SCYDEGKRCAETLFFDYWRQHKLEIKVTRIFNTYGPRMHPNDGRVVSNFIVQALRGEPITIYGDGTQTRSFCYVDDLIDG
MLRMMESPKDFNGPVNIGNPTEFTMLQLAEMVLKLVGSISKIVFQPLPLDDPKQRQPDITLAKSQLGWEPKVSLEDGLRE
TIAYFRKRV

Sequences:

>Translated_329_residues
MVDQAWILKCSYGVPMSGNNNRVLVTGGAGFLGSHLCEKLVASGHDVLCVDNFYTGSKDSVINLIGHPKFELIRHDVTFP
LYVEVDRIYNLACPASPVHYQHDPVQTTKTSVHGAINMLGLAKRVKARILQASTSEVYGDPEIHPQLETYWGRVNPVGIR
SCYDEGKRCAETLFFDYWRQHKLEIKVTRIFNTYGPRMHPNDGRVVSNFIVQALRGEPITIYGDGTQTRSFCYVDDLIDG
MLRMMESPKDFNGPVNIGNPTEFTMLQLAEMVLKLVGSISKIVFQPLPLDDPKQRQPDITLAKSQLGWEPKVSLEDGLRE
TIAYFRKRV
>Mature_329_residues
MVDQAWILKCSYGVPMSGNNNRVLVTGGAGFLGSHLCEKLVASGHDVLCVDNFYTGSKDSVINLIGHPKFELIRHDVTFP
LYVEVDRIYNLACPASPVHYQHDPVQTTKTSVHGAINMLGLAKRVKARILQASTSEVYGDPEIHPQLETYWGRVNPVGIR
SCYDEGKRCAETLFFDYWRQHKLEIKVTRIFNTYGPRMHPNDGRVVSNFIVQALRGEPITIYGDGTQTRSFCYVDDLIDG
MLRMMESPKDFNGPVNIGNPTEFTMLQLAEMVLKLVGSISKIVFQPLPLDDPKQRQPDITLAKSQLGWEPKVSLEDGLRE
TIAYFRKRV

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=308, Percent_Identity=60.3896103896104, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI7657641, Length=336, Percent_Identity=27.9761904761905, Blast_Score=114, Evalue=9e-26,
Organism=Escherichia coli, GI1788589, Length=349, Percent_Identity=27.2206303724928, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI48994969, Length=337, Percent_Identity=24.3323442136499, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=27.2455089820359, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788353, Length=336, Percent_Identity=24.1071428571429, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788365, Length=164, Percent_Identity=27.4390243902439, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=309, Percent_Identity=59.546925566343, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI115532424, Length=334, Percent_Identity=26.9461077844311, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17568069, Length=339, Percent_Identity=26.2536873156342, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=338, Percent_Identity=25.4437869822485, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71982038, Length=340, Percent_Identity=25.2941176470588, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=345, Percent_Identity=23.4782608695652, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356223, Length=311, Percent_Identity=59.8070739549839, Blast_Score=400, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37077; Mature: 37077

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDQAWILKCSYGVPMSGNNNRVLVTGGAGFLGSHLCEKLVASGHDVLCVDNFYTGSKDS
CCCCEEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
VINLIGHPKFELIRHDVTFPLYVEVDRIYNLACPASPVHYQHDPVQTTKTSVHGAINMLG
EEEECCCCHHHHHHHCCCCEEEEEEEHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LAKRVKARILQASTSEVYGDPEIHPQLETYWGRVNPVGIRSCYDEGKRCAETLFFDYWRQ
HHHHHHHHHHHHCHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
HKLEIKVTRIFNTYGPRMHPNDGRVVSNFIVQALRGEPITIYGDGTQTRSFCYVDDLIDG
CEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHH
MLRMMESPKDFNGPVNIGNPTEFTMLQLAEMVLKLVGSISKIVFQPLPLDDPKQRQPDIT
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
LAKSQLGWEPKVSLEDGLRETIAYFRKRV
EEHHHCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVDQAWILKCSYGVPMSGNNNRVLVTGGAGFLGSHLCEKLVASGHDVLCVDNFYTGSKDS
CCCCEEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
VINLIGHPKFELIRHDVTFPLYVEVDRIYNLACPASPVHYQHDPVQTTKTSVHGAINMLG
EEEECCCCHHHHHHHCCCCEEEEEEEHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LAKRVKARILQASTSEVYGDPEIHPQLETYWGRVNPVGIRSCYDEGKRCAETLFFDYWRQ
HHHHHHHHHHHHCHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
HKLEIKVTRIFNTYGPRMHPNDGRVVSNFIVQALRGEPITIYGDGTQTRSFCYVDDLIDG
CEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHH
MLRMMESPKDFNGPVNIGNPTEFTMLQLAEMVLKLVGSISKIVFQPLPLDDPKQRQPDIT
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
LAKSQLGWEPKVSLEDGLRETIAYFRKRV
EEHHHCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]