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The map label for this gene is fabD [H]

Identifier: 62185100

GI number: 62185100

Start: 544092

End: 545018

Strand: Direct

Name: fabD [H]

Synonym: CAB471

Alternate gene names: 62185100

Gene position: 544092-545018 (Clockwise)

Preceding gene: 62185099

Following gene: 62185101

Centisome position: 47.54

GC content: 37.32

Gene sequence:

>927_bases
ATGACGAAAAAAATAGGATTTTTATTTCCAGGTCAAGGTAGTCAATACGTTGGTATGGGTAAAGATTTAGTAGAGAACTA
TCCAGAAGCAGAAAAAGTTTTTGCTTTGGCGGATGAGACTTTAGGGTTTTCTTTATCCTCAATTATGTTTCATGGGCCTG
AAGAGAAGTTGCTTGAAACTGCATATAGCCAACTCGCCATATACTTACATAGTTTAGCTGTGGTTGAAATTTTATCTTCC
AGAACTTCTATAACCCCTGCAGCGGTTACAGGTTTAAGTCTGGGAGAGTATACTGCTCTCGTGGCTTCTGGACGCATTTC
TCCAGTTGATGGCTTTGATATTATTAGTAAACGTGCTCAATTTATGAATCAGGCCTGTCAAGAAAATCCTGGTGCTATGG
CAGCAGTTTTGGGATTGACCGCAGACGTTATTGAGCAGAATTTAGAAAGTTTGGGAGAGGGGATTTGGGTTGCCAACTAC
AATGCTCCTAAACAACTAGTTATTGCTGGTCTAAGAGAAAAAATAGAAGAAGCTGTTAAATTATTTACAGATTTAGGAGC
CAAAAGGGCGATACTATTAAAAGTATTTGGAGCTTTTCATACCCCACTGATGCAGTCAGCTGAAGATAAGTTAGCGCCGT
ACTTATATAATTTGCATATGCATAGTTCTGAAATTCCTTTTGTATCTAATGTTACAGCTAGCTTTCTAAGGAATAACGAT
GAAATTCTTCAGTGTTTGGTCAAGCAAATGACTTCTCCCACGTTATGGTATCAGAGTTGTTCTAAAATAGATTTGGAAGT
TGATGAATTTTTAGAACTTGGTCCGGGTAAAGTTCTTGCTGGATTGAATCGTTCTATAGGATTAAATAAACCCATTAAAA
GTTTAGGTACAGTAGAAAGCATCAATAATTTTTTATCAGGGCTATAG

Upstream 100 bases:

>100_bases
GCAATCGCATATAATTCATGCTGGGGAATACCTGCTTCTAGTTGCTTTTGGAGGAGGGTTATCCTGGGGAGCAGTTGTTT
TACAACAGGTAGAAAGTTAA

Downstream 100 bases:

>100_bases
ATATATGAATGGTATATTGTCGGGAAAGAAAGCGATCGTTACAGGGGGATCTAGAGGTATAGGATTTGCCATTAGTAAGC
TTTTTGTAGAGCAAGGTGCG

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTKKIGFLFPGQGSQYVGMGKDLVENYPEAEKVFALADETLGFSLSSIMFHGPEEKLLETAYSQLAIYLHSLAVVEILSS
RTSITPAAVTGLSLGEYTALVASGRISPVDGFDIISKRAQFMNQACQENPGAMAAVLGLTADVIEQNLESLGEGIWVANY
NAPKQLVIAGLREKIEEAVKLFTDLGAKRAILLKVFGAFHTPLMQSAEDKLAPYLYNLHMHSSEIPFVSNVTASFLRNND
EILQCLVKQMTSPTLWYQSCSKIDLEVDEFLELGPGKVLAGLNRSIGLNKPIKSLGTVESINNFLSGL

Sequences:

>Translated_308_residues
MTKKIGFLFPGQGSQYVGMGKDLVENYPEAEKVFALADETLGFSLSSIMFHGPEEKLLETAYSQLAIYLHSLAVVEILSS
RTSITPAAVTGLSLGEYTALVASGRISPVDGFDIISKRAQFMNQACQENPGAMAAVLGLTADVIEQNLESLGEGIWVANY
NAPKQLVIAGLREKIEEAVKLFTDLGAKRAILLKVFGAFHTPLMQSAEDKLAPYLYNLHMHSSEIPFVSNVTASFLRNND
EILQCLVKQMTSPTLWYQSCSKIDLEVDEFLELGPGKVLAGLNRSIGLNKPIKSLGTVESINNFLSGL
>Mature_307_residues
TKKIGFLFPGQGSQYVGMGKDLVENYPEAEKVFALADETLGFSLSSIMFHGPEEKLLETAYSQLAIYLHSLAVVEILSSR
TSITPAAVTGLSLGEYTALVASGRISPVDGFDIISKRAQFMNQACQENPGAMAAVLGLTADVIEQNLESLGEGIWVANYN
APKQLVIAGLREKIEEAVKLFTDLGAKRAILLKVFGAFHTPLMQSAEDKLAPYLYNLHMHSSEIPFVSNVTASFLRNNDE
ILQCLVKQMTSPTLWYQSCSKIDLEVDEFLELGPGKVLAGLNRSIGLNKPIKSLGTVESINNFLSGL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=304, Percent_Identity=32.8947368421053, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI27477045, Length=114, Percent_Identity=41.2280701754386, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1787334, Length=298, Percent_Identity=38.5906040268456, Blast_Score=182, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=28.9115646258503, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=28.2312925170068, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24665753, Length=291, Percent_Identity=36.0824742268041, Blast_Score=148, Evalue=4e-36,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33495; Mature: 33364

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKIGFLFPGQGSQYVGMGKDLVENYPEAEKVFALADETLGFSLSSIMFHGPEEKLLET
CCCCCCEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
AYSQLAIYLHSLAVVEILSSRTSITPAAVTGLSLGEYTALVASGRISPVDGFDIISKRAQ
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHH
FMNQACQENPGAMAAVLGLTADVIEQNLESLGEGIWVANYNAPKQLVIAGLREKIEEAVK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHH
LFTDLGAKRAILLKVFGAFHTPLMQSAEDKLAPYLYNLHMHSSEIPFVSNVTASFLRNND
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCH
EILQCLVKQMTSPTLWYQSCSKIDLEVDEFLELGPGKVLAGLNRSIGLNKPIKSLGTVES
HHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHH
INNFLSGL
HHHHHCCC
>Mature Secondary Structure 
TKKIGFLFPGQGSQYVGMGKDLVENYPEAEKVFALADETLGFSLSSIMFHGPEEKLLET
CCCCCEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
AYSQLAIYLHSLAVVEILSSRTSITPAAVTGLSLGEYTALVASGRISPVDGFDIISKRAQ
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHH
FMNQACQENPGAMAAVLGLTADVIEQNLESLGEGIWVANYNAPKQLVIAGLREKIEEAVK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHH
LFTDLGAKRAILLKVFGAFHTPLMQSAEDKLAPYLYNLHMHSSEIPFVSNVTASFLRNND
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCH
EILQCLVKQMTSPTLWYQSCSKIDLEVDEFLELGPGKVLAGLNRSIGLNKPIKSLGTVES
HHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHH
INNFLSGL
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]