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The map label for this gene is fabH [H]

Identifier: 62185099

GI number: 62185099

Start: 543078

End: 544091

Strand: Direct

Name: fabH [H]

Synonym: CAB470

Alternate gene names: 62185099

Gene position: 543078-544091 (Clockwise)

Preceding gene: 62185094

Following gene: 62185100

Centisome position: 47.46

GC content: 40.83

Gene sequence:

>1014_bases
TTGTGGTTATGCGTGAAAAAAACAAGAAAGGCATCTATATGGGCTACAGGTTCTTATTTGCCCGAAAAAATCCTATCTAA
TTCTGATCTTGAACAGATGGTTGATACTTCGGATGAATGGATATTAACAAGAACCGGAATCAAAGAAAGGCGTATTGCAG
CAGCGAATGAATATACTTCCATCATGGGAGCTAAAGCTGCTGAAAGAGCAATACAGAAAGCAGGTCTAACTAAAGACCAA
ATAGAATGTATTATTTTTTCTACATCGGCCCCCGATTATATTTTCCCTTCAAGCGCGGCCTTAGCTCAAGCTTATTTGGG
AATAAAAGACATTCCAGCATTTGATTGTATGGCTGCGTGTACTGGTTACTTATATGGCTTATCAGTGGCTAAAGCCTATG
TTGAATCAGGGATGTATAATAATGTCTTGCTGATTGCAGCAGATAAACTCTCTTCTTTTGTAAATTATAAGGATAGAAAC
ACCTGTGTTCTTTTTGGGGATGGAGGTGCTGCCTGCATTATTGGAGAGAGTCGTCCTGGAGCTTTAGAAATCACTAATGT
GAATTTAGGAGCAGACGGAAGCGTAGCCGATCTATTGAGTCTTCCTGCTGGGGGGAGTCGTGTTCCTGCTTCCCAAGAGA
CTTTAGAAGCGGGTAAGCACTACATTTTTATGGAAGGTAAAGAAGTGTTTAAACATGCGGTAAGACGCATGGAGTCCGCG
GCTAAAACTTGTATTGCTGGCGCTGGAATTGAAGAAAGTGACATAGACTGGTTGGTTCCTCACCAAGCAAATGAAAGAAT
TATTGACGCTATAGCTAAACGTTTTGAAATCGACGAAGGTAAAGTATTTAAGACGTTGTGTAAGTATGGAAACACAGCTG
CTTCTTCTGTATGCATAGCTCTTGATGAGTTATTGCAATCGCATATAATTCATGCTGGGGAATACCTGCTTCTAGTTGCT
TTTGGAGGAGGGTTATCCTGGGGAGCAGTTGTTTTACAACAGGTAGAAAGTTAA

Upstream 100 bases:

>100_bases
AATTTTTTATTGCACCTCAGGGTCGCAGAAAGGGCTTAAATACTTAAAATAAAAGTTAGGGTATAAACTCTTTGAATAGT
ATACTAGCTTTTTTCTTTAT

Downstream 100 bases:

>100_bases
ATGACGAAAAAAATAGGATTTTTATTTCCAGGTCAAGGTAGTCAATACGTTGGTATGGGTAAAGATTTAGTAGAGAACTA
TCCAGAAGCAGAAAAAGTTT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MWLCVKKTRKASIWATGSYLPEKILSNSDLEQMVDTSDEWILTRTGIKERRIAAANEYTSIMGAKAAERAIQKAGLTKDQ
IECIIFSTSAPDYIFPSSAALAQAYLGIKDIPAFDCMAACTGYLYGLSVAKAYVESGMYNNVLLIAADKLSSFVNYKDRN
TCVLFGDGGAACIIGESRPGALEITNVNLGADGSVADLLSLPAGGSRVPASQETLEAGKHYIFMEGKEVFKHAVRRMESA
AKTCIAGAGIEESDIDWLVPHQANERIIDAIAKRFEIDEGKVFKTLCKYGNTAASSVCIALDELLQSHIIHAGEYLLLVA
FGGGLSWGAVVLQQVES

Sequences:

>Translated_337_residues
MWLCVKKTRKASIWATGSYLPEKILSNSDLEQMVDTSDEWILTRTGIKERRIAAANEYTSIMGAKAAERAIQKAGLTKDQ
IECIIFSTSAPDYIFPSSAALAQAYLGIKDIPAFDCMAACTGYLYGLSVAKAYVESGMYNNVLLIAADKLSSFVNYKDRN
TCVLFGDGGAACIIGESRPGALEITNVNLGADGSVADLLSLPAGGSRVPASQETLEAGKHYIFMEGKEVFKHAVRRMESA
AKTCIAGAGIEESDIDWLVPHQANERIIDAIAKRFEIDEGKVFKTLCKYGNTAASSVCIALDELLQSHIIHAGEYLLLVA
FGGGLSWGAVVLQQVES
>Mature_337_residues
MWLCVKKTRKASIWATGSYLPEKILSNSDLEQMVDTSDEWILTRTGIKERRIAAANEYTSIMGAKAAERAIQKAGLTKDQ
IECIIFSTSAPDYIFPSSAALAQAYLGIKDIPAFDCMAACTGYLYGLSVAKAYVESGMYNNVLLIAADKLSSFVNYKDRN
TCVLFGDGGAACIIGESRPGALEITNVNLGADGSVADLLSLPAGGSRVPASQETLEAGKHYIFMEGKEVFKHAVRRMESA
AKTCIAGAGIEESDIDWLVPHQANERIIDAIAKRFEIDEGKVFKTLCKYGNTAASSVCIALDELLQSHIIHAGEYLLLVA
FGGGLSWGAVVLQQVES

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=46.583850931677, Blast_Score=281, Evalue=4e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36299; Mature: 36299

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLCVKKTRKASIWATGSYLPEKILSNSDLEQMVDTSDEWILTRTGIKERRIAAANEYTS
CEEEECCCCCCEEEECCCCCHHHHHCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHH
IMGAKAAERAIQKAGLTKDQIECIIFSTSAPDYIFPSSAALAQAYLGIKDIPAFDCMAAC
HHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHH
TGYLYGLSVAKAYVESGMYNNVLLIAADKLSSFVNYKDRNTCVLFGDGGAACIIGESRPG
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCC
ALEITNVNLGADGSVADLLSLPAGGSRVPASQETLEAGKHYIFMEGKEVFKHAVRRMESA
EEEEEEEECCCCCCHHHHHHCCCCCCCCCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHH
AKTCIAGAGIEESDIDWLVPHQANERIIDAIAKRFEIDEGKVFKTLCKYGNTAASSVCIA
HHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHH
LDELLQSHIIHAGEYLLLVAFGGGLSWGAVVLQQVES
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MWLCVKKTRKASIWATGSYLPEKILSNSDLEQMVDTSDEWILTRTGIKERRIAAANEYTS
CEEEECCCCCCEEEECCCCCHHHHHCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHH
IMGAKAAERAIQKAGLTKDQIECIIFSTSAPDYIFPSSAALAQAYLGIKDIPAFDCMAAC
HHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHH
TGYLYGLSVAKAYVESGMYNNVLLIAADKLSSFVNYKDRNTCVLFGDGGAACIIGESRPG
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCC
ALEITNVNLGADGSVADLLSLPAGGSRVPASQETLEAGKHYIFMEGKEVFKHAVRRMESA
EEEEEEEECCCCCCHHHHHHCCCCCCCCCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHH
AKTCIAGAGIEESDIDWLVPHQANERIIDAIAKRFEIDEGKVFKTLCKYGNTAASSVCIA
HHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHH
LDELLQSHIIHAGEYLLLVAFGGGLSWGAVVLQQVES
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]