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The map label for this gene is ribC [H]

Identifier: 62184852

GI number: 62184852

Start: 229735

End: 230328

Strand: Direct

Name: ribC [H]

Synonym: CAB208

Alternate gene names: 62184852

Gene position: 229735-230328 (Clockwise)

Preceding gene: 62184843

Following gene: 62184853

Centisome position: 20.08

GC content: 40.57

Gene sequence:

>594_bases
ATGTTTTCTGGAATAGTGCAAGAACTCGGTAAAATATTTAGTATAGAACCGAGAGATGAAGGTTTAACGATAGGCGTGGA
GGTTTCTTCCTCCTGTATTTCAGGACTCGAAATCGGTTGTAGTGTTGCTATCGATGGCGTCTGTCTTACTGTAGTTAAAC
TTGAAGAGGGCGGTAAAATGTTTTTCGACATTATTCCCGAGACTCTTGCCTGTACGACAATAGGCGAGAAGGTAATAAAT
GATCGTGTAAATGTCGAACGATCTTTAAAAGTGAGCGATGAAATTGGTGGGCATAGCGTCTCTGGTCATGTTTCTGGTGT
CGGAGAGATTGTGCTTATAGAGAAAAATCGGTATTATTTTCGTGTGCCAAGTTCCTTATCTGTATACCTTTTTGAAAAAG
GATATATTGCTATCGATGGCATTAGTCTGACTATCGTCACTGTAGAAGAGGATGTGTGTTCGGTCGGATTGATCCCCGAA
ACATTATTTCGAACAACCTTAGGATATAAACGAGAAGGATCCAAAGTAAATATAGAGCCGGATATGGCGACCAAAACACA
AGTGGATACGTTAAGGCGTCTCTATCTTCGATAA

Upstream 100 bases:

>100_bases
AAAGACAGATTGCTTGATATAGTTTCGCTACCTTGGCGAAACGACAGCATTTTGTCGGAAAGCTGTTTTATTGTAAATAC
TAGATGCTCAGGATTTAATA

Downstream 100 bases:

>100_bases
ACAAACAAATATATGACTTATAAGTTACTCGATAGCGGTGAAGGGAAAAAGTTAGAAAGCTTTGGCCCCATAACTCTTAT
CCGCCCCTCTTGTACGGCAA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MFSGIVQELGKIFSIEPRDEGLTIGVEVSSSCISGLEIGCSVAIDGVCLTVVKLEEGGKMFFDIIPETLACTTIGEKVIN
DRVNVERSLKVSDEIGGHSVSGHVSGVGEIVLIEKNRYYFRVPSSLSVYLFEKGYIAIDGISLTIVTVEEDVCSVGLIPE
TLFRTTLGYKREGSKVNIEPDMATKTQVDTLRRLYLR

Sequences:

>Translated_197_residues
MFSGIVQELGKIFSIEPRDEGLTIGVEVSSSCISGLEIGCSVAIDGVCLTVVKLEEGGKMFFDIIPETLACTTIGEKVIN
DRVNVERSLKVSDEIGGHSVSGHVSGVGEIVLIEKNRYYFRVPSSLSVYLFEKGYIAIDGISLTIVTVEEDVCSVGLIPE
TLFRTTLGYKREGSKVNIEPDMATKTQVDTLRRLYLR
>Mature_197_residues
MFSGIVQELGKIFSIEPRDEGLTIGVEVSSSCISGLEIGCSVAIDGVCLTVVKLEEGGKMFFDIIPETLACTTIGEKVIN
DRVNVERSLKVSDEIGGHSVSGHVSGVGEIVLIEKNRYYFRVPSSLSVYLFEKGYIAIDGISLTIVTVEEDVCSVGLIPE
TLFRTTLGYKREGSKVNIEPDMATKTQVDTLRRLYLR

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=199, Percent_Identity=47.2361809045226, Blast_Score=156, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6319733, Length=207, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21516; Mature: 21516

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGIVQELGKIFSIEPRDEGLTIGVEVSSSCISGLEIGCSVAIDGVCLTVVKLEEGGKM
CCHHHHHHHHHHEECCCCCCCEEEEEEECCHHHCCCCCCEEEEECCEEEEEEEECCCCEE
FFDIIPETLACTTIGEKVINDRVNVERSLKVSDEIGGHSVSGHVSGVGEIVLIEKNRYYF
EEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEECCCCCCCEEEEEEECCCEEE
RVPSSLSVYLFEKGYIAIDGISLTIVTVEEDVCSVGLIPETLFRTTLGYKREGSKVNIEP
ECCCCEEEEEEECCEEEECCEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCEEEECC
DMATKTQVDTLRRLYLR
CCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MFSGIVQELGKIFSIEPRDEGLTIGVEVSSSCISGLEIGCSVAIDGVCLTVVKLEEGGKM
CCHHHHHHHHHHEECCCCCCCEEEEEEECCHHHCCCCCCEEEEECCEEEEEEEECCCCEE
FFDIIPETLACTTIGEKVINDRVNVERSLKVSDEIGGHSVSGHVSGVGEIVLIEKNRYYF
EEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEECCCCCCCEEEEEEECCCEEE
RVPSSLSVYLFEKGYIAIDGISLTIVTVEEDVCSVGLIPETLFRTTLGYKREGSKVNIEP
ECCCCEEEEEEECCEEEECCEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCEEEECC
DMATKTQVDTLRRLYLR
CCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]