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The map label for this gene is aspC [H]

Identifier: 62184652

GI number: 62184652

Start: 5450

End: 6643

Strand: Direct

Name: aspC [H]

Synonym: CAB005

Alternate gene names: 62184652

Gene position: 5450-6643 (Clockwise)

Preceding gene: 62184651

Following gene: 62184653

Centisome position: 0.48

GC content: 38.53

Gene sequence:

>1194_bases
ATGAGTTTTTTTCATCAATTACCCACGTTTGCTCCCGATTCTATTTTGGGTTTGCAAAAACTATTTTTAGAAGACGAGCG
AGAGGAGAAGGTCAATCTTGTTATAGGTTCTTATGAAGATCCTAACAAGGCTTATGGTGGCTTTTCGAGTGTCCGCAAGG
CGCAATTTTCATTGTTAGAAAACGAGATGAATAAAGGGTACTTACCTATTAGTGGGTTATTGTCTTTTAATCAGCAAATG
GAAAGTCTTGTTTTTGGTGATGATGTAAATCCGAGTTTTGTTGTTGGTGCCCAAGCTCTCGGGGGAACGGGAGCGTTGCA
TTTAGGTGCTAAGATTTTCGCCATGGCTCACCCTTCTGCTGCAGTATACATTCCCGAACAGACATGGGGAAACCATTTGA
GAATATTTGCTCAACAAGGTTTAGATGTTCTAAAATATCCTTATTATAGTTCAGAAAGTAAAACACTCGTTTTTGATGAG
ATGATTTCTGTATTGAAATCTGCTCCCAAGAACTCTTTAGTGCTTTTGCAATGTTGTTGTCATAATCCTACAGGAATGGA
CCTTGACGAGAACATGTGGACTCGTCTTGCAGAACTGATGAAAGAACGTCAGCTTCTTCCTTTTTTTGATACGGCGTATT
TAGGCTTTGGGTTAGGTATCGAAGAAGATAGAAAGCCTATAAAGATTTTTATAGATTCAGGGCATACTGTATTTGTAGCC
GCATGCGCAAGTAAGAATTTTTCTCTTTATGGGGAGCGTGTAGGCTATTTTGCTGCATATAGTCGGGTTGTTGATGATTT
AGATAAGATTTCTAGCTGTCTCGAAGAAAAAATACGAGGAGAGTATTCTTCACCACCTCGACATGGAGCGAAAATTGTTT
CTACAATTTTATCAGATGCCTCTTTAAAAACAGAATGGTTGGCAGAATTAGACACGATTCGTTGTTCTTTACAAAAAACA
CGCACGCGATTTGTTCAGGCTATGCGCAATCATATTGGTCATTCTTTTGATTTTATCCTATCTCAGAAAGGATTTTTTGG
TTACCCAGGATTTTCTTTAGAACAAGTCTTATTTTTAAGATTAGAAAAAGGTATTTACACAACCAGTGGAGCCAGGTTTA
ATCTCAACGGAATCACCGATAATAACATCGATCATGTAGTTCAGAGCTTTGCTGAGGCATACCAACAAGCTTAG

Upstream 100 bases:

>100_bases
TTGCGCTCTACCAATTGAGCTAATACCCCAAGTAGATAAAATTATCATGAGGTAAGGTTTAGAATCAATCTTTGTTACAA
TACGAAGGAATTTCTTTGGT

Downstream 100 bases:

>100_bases
TGTACTGAGTTTGATATAACATGATTTCGCTTTGTTGATTACATCTACTCATAATGATAGCGCAGATGCATATCTGCGCG
TATTTTTCATTCACATTACA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSFFHQLPTFAPDSILGLQKLFLEDEREEKVNLVIGSYEDPNKAYGGFSSVRKAQFSLLENEMNKGYLPISGLLSFNQQM
ESLVFGDDVNPSFVVGAQALGGTGALHLGAKIFAMAHPSAAVYIPEQTWGNHLRIFAQQGLDVLKYPYYSSESKTLVFDE
MISVLKSAPKNSLVLLQCCCHNPTGMDLDENMWTRLAELMKERQLLPFFDTAYLGFGLGIEEDRKPIKIFIDSGHTVFVA
ACASKNFSLYGERVGYFAAYSRVVDDLDKISSCLEEKIRGEYSSPPRHGAKIVSTILSDASLKTEWLAELDTIRCSLQKT
RTRFVQAMRNHIGHSFDFILSQKGFFGYPGFSLEQVLFLRLEKGIYTTSGARFNLNGITDNNIDHVVQSFAEAYQQA

Sequences:

>Translated_397_residues
MSFFHQLPTFAPDSILGLQKLFLEDEREEKVNLVIGSYEDPNKAYGGFSSVRKAQFSLLENEMNKGYLPISGLLSFNQQM
ESLVFGDDVNPSFVVGAQALGGTGALHLGAKIFAMAHPSAAVYIPEQTWGNHLRIFAQQGLDVLKYPYYSSESKTLVFDE
MISVLKSAPKNSLVLLQCCCHNPTGMDLDENMWTRLAELMKERQLLPFFDTAYLGFGLGIEEDRKPIKIFIDSGHTVFVA
ACASKNFSLYGERVGYFAAYSRVVDDLDKISSCLEEKIRGEYSSPPRHGAKIVSTILSDASLKTEWLAELDTIRCSLQKT
RTRFVQAMRNHIGHSFDFILSQKGFFGYPGFSLEQVLFLRLEKGIYTTSGARFNLNGITDNNIDHVVQSFAEAYQQA
>Mature_396_residues
SFFHQLPTFAPDSILGLQKLFLEDEREEKVNLVIGSYEDPNKAYGGFSSVRKAQFSLLENEMNKGYLPISGLLSFNQQME
SLVFGDDVNPSFVVGAQALGGTGALHLGAKIFAMAHPSAAVYIPEQTWGNHLRIFAQQGLDVLKYPYYSSESKTLVFDEM
ISVLKSAPKNSLVLLQCCCHNPTGMDLDENMWTRLAELMKERQLLPFFDTAYLGFGLGIEEDRKPIKIFIDSGHTVFVAA
CASKNFSLYGERVGYFAAYSRVVDDLDKISSCLEEKIRGEYSSPPRHGAKIVSTILSDASLKTEWLAELDTIRCSLQKTR
TRFVQAMRNHIGHSFDFILSQKGFFGYPGFSLEQVLFLRLEKGIYTTSGARFNLNGITDNNIDHVVQSFAEAYQQA

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4504067, Length=407, Percent_Identity=34.6437346437346, Blast_Score=235, Evalue=5e-62,
Organism=Homo sapiens, GI73486658, Length=385, Percent_Identity=34.025974025974, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI117414139, Length=351, Percent_Identity=27.0655270655271, Blast_Score=135, Evalue=9e-32,
Organism=Escherichia coli, GI1787159, Length=392, Percent_Identity=38.7755102040816, Blast_Score=281, Evalue=7e-77,
Organism=Escherichia coli, GI1790488, Length=396, Percent_Identity=36.8686868686869, Blast_Score=279, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=32.9113924050633, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI25147133, Length=396, Percent_Identity=31.8181818181818, Blast_Score=237, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI17569539, Length=403, Percent_Identity=30.272952853598, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI25147136, Length=214, Percent_Identity=32.7102803738318, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17569537, Length=402, Percent_Identity=25.1243781094527, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17550384, Length=255, Percent_Identity=29.4117647058824, Blast_Score=132, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6323055, Length=411, Percent_Identity=31.6301703163017, Blast_Score=235, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6322743, Length=435, Percent_Identity=30.3448275862069, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24580970, Length=395, Percent_Identity=33.6708860759494, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI24580972, Length=395, Percent_Identity=33.6708860759494, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI19920542, Length=385, Percent_Identity=34.2857142857143, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI19922362, Length=404, Percent_Identity=31.9306930693069, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24654046, Length=404, Percent_Identity=31.9306930693069, Blast_Score=230, Evalue=2e-60,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44442; Mature: 44311

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFHQLPTFAPDSILGLQKLFLEDEREEKVNLVIGSYEDPNKAYGGFSSVRKAQFSLLE
CCHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHCCCHHHHHHHHHHHHH
NEMNKGYLPISGLLSFNQQMESLVFGDDVNPSFVVGAQALGGTGALHLGAKIFAMAHPSA
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECHHCCCCCHHHHCCEEEEEECCCE
AVYIPEQTWGNHLRIFAQQGLDVLKYPYYSSESKTLVFDEMISVLKSAPKNSLVLLQCCC
EEEECCCCCCCCEEHHHHCCCHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCCEEEEEEEC
HNPTGMDLDENMWTRLAELMKERQLLPFFDTAYLGFGLGIEEDRKPIKIFIDSGHTVFVA
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEE
ACASKNFSLYGERVGYFAAYSRVVDDLDKISSCLEEKIRGEYSSPPRHGAKIVSTILSDA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
SLKTEWLAELDTIRCSLQKTRTRFVQAMRNHIGHSFDFILSQKGFFGYPGFSLEQVLFLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHEECCCCCCCCCCCHHHHHHHH
LEKGIYTTSGARFNLNGITDNNIDHVVQSFAEAYQQA
HHCCEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFFHQLPTFAPDSILGLQKLFLEDEREEKVNLVIGSYEDPNKAYGGFSSVRKAQFSLLE
CHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHCCCHHHHHHHHHHHHH
NEMNKGYLPISGLLSFNQQMESLVFGDDVNPSFVVGAQALGGTGALHLGAKIFAMAHPSA
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECHHCCCCCHHHHCCEEEEEECCCE
AVYIPEQTWGNHLRIFAQQGLDVLKYPYYSSESKTLVFDEMISVLKSAPKNSLVLLQCCC
EEEECCCCCCCCEEHHHHCCCHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCCEEEEEEEC
HNPTGMDLDENMWTRLAELMKERQLLPFFDTAYLGFGLGIEEDRKPIKIFIDSGHTVFVA
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEE
ACASKNFSLYGERVGYFAAYSRVVDDLDKISSCLEEKIRGEYSSPPRHGAKIVSTILSDA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
SLKTEWLAELDTIRCSLQKTRTRFVQAMRNHIGHSFDFILSQKGFFGYPGFSLEQVLFLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHEECCCCCCCCCCCHHHHHHHH
LEKGIYTTSGARFNLNGITDNNIDHVVQSFAEAYQQA
HHCCEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]