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The map label for this gene is purQ [H]

Identifier: 28572946

GI number: 28572946

Start: 913300

End: 913980

Strand: Reverse

Name: purQ [H]

Synonym: TW805

Alternate gene names: 28572946

Gene position: 913980-913300 (Counterclockwise)

Preceding gene: 28572947

Following gene: 28572945

Centisome position: 98.71

GC content: 46.84

Gene sequence:

>681_bases
TTGGTTAGAGTTGGCGTAGTTACATTCCCGGGATCGCTTGATGACAAGCAGACCTTGCGTGCCCTTTCTTTTGCTGGGTG
TGCAGCTGTTCAACTTTGGCATGCAAGCGATACGCTGTCTTCGGTTGACGCCGTTATCCTCCCAGGGGGTTTTAGTTATG
GCGACTATCTGCGCCCCGGCGCACTCGCAAGCCGCTCAAGGATTATGGTCAGGATTATTGAAGCTGCACATCAGGGTATG
CCTGTTTTGGGGATATGCAATGGCTTTCAGCTCTTGACTGAATCAAGATTGCTTCCGGGGGCATTTGTTGCAAACAAAGC
ATCACGGTTCGTATGTCTGGAACAGAGTCTAATTGTGGAGAATAATTCCACTCCATTTACCATGAATTTCTCTAAAAATC
AGAATGTTATTATCCCGATAAAAAATTCGGACGGATGTTATTTTGCTCAAACCGAGGATCTTGATCGTATTGAAAATGAG
GGGCGGGTTGTTCTTCGGTATGCTGGGTCTAACCCAAGTGGTTCGTCAAGAAATATTGCAGGTATTTGTAATGAACAGGG
GAATATTGTTGGCATGATGCCACATCCAGAGTATGCTGTTGAACCTGGCTTTGGTCCACCCGGGCTACACGGTGCCCCTG
TTTTTTCTGCCATTTCTTCATGGATTAACAACGCCCGATAG

Upstream 100 bases:

>100_bases
GACGTGCGAATTGGATTTTATCCGTGATCTTGCCAATGACCTGTTGATCAACCCGGTCATAGAGGATGTTGTTGATATCA
GGATCGAGGATGACTGAAAC

Downstream 100 bases:

>100_bases
GCATTGCATGATTTGTGTTAGACAGGAGAATAGCTTTTGCCGTATACCGCGACCGCTCCTCGGCCAACATTGTTTCTGGT
CTATGAGCCCGACTGAGGGT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MVRVGVVTFPGSLDDKQTLRALSFAGCAAVQLWHASDTLSSVDAVILPGGFSYGDYLRPGALASRSRIMVRIIEAAHQGM
PVLGICNGFQLLTESRLLPGAFVANKASRFVCLEQSLIVENNSTPFTMNFSKNQNVIIPIKNSDGCYFAQTEDLDRIENE
GRVVLRYAGSNPSGSSRNIAGICNEQGNIVGMMPHPEYAVEPGFGPPGLHGAPVFSAISSWINNAR

Sequences:

>Translated_226_residues
MVRVGVVTFPGSLDDKQTLRALSFAGCAAVQLWHASDTLSSVDAVILPGGFSYGDYLRPGALASRSRIMVRIIEAAHQGM
PVLGICNGFQLLTESRLLPGAFVANKASRFVCLEQSLIVENNSTPFTMNFSKNQNVIIPIKNSDGCYFAQTEDLDRIENE
GRVVLRYAGSNPSGSSRNIAGICNEQGNIVGMMPHPEYAVEPGFGPPGLHGAPVFSAISSWINNAR
>Mature_226_residues
MVRVGVVTFPGSLDDKQTLRALSFAGCAAVQLWHASDTLSSVDAVILPGGFSYGDYLRPGALASRSRIMVRIIEAAHQGM
PVLGICNGFQLLTESRLLPGAFVANKASRFVCLEQSLIVENNSTPFTMNFSKNQNVIIPIKNSDGCYFAQTEDLDRIENE
GRVVLRYAGSNPSGSSRNIAGICNEQGNIVGMMPHPEYAVEPGFGPPGLHGAPVFSAISSWINNAR

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=226, Percent_Identity=29.2035398230088, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321498, Length=179, Percent_Identity=28.4916201117318, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24260; Mature: 24260

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRVGVVTFPGSLDDKQTLRALSFAGCAAVQLWHASDTLSSVDAVILPGGFSYGDYLRPG
CEEEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCC
ALASRSRIMVRIIEAAHQGMPVLGICNGFQLLTESRLLPGAFVANKASRFVCLEQSLIVE
CCCHHHHHHHHEEHHHHCCCCEEEECCCHHHHHHCCCCCCHHHHCCCCEEEEEECEEEEE
NNSTPFTMNFSKNQNVIIPIKNSDGCYFAQTEDLDRIENEGRVVLRYAGSNPSGSSRNIA
CCCCCEEEEECCCCEEEEEEECCCCEEEECCCCHHHHCCCCEEEEEECCCCCCCCCCCEE
GICNEQGNIVGMMPHPEYAVEPGFGPPGLHGAPVFSAISSWINNAR
EEECCCCCEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MVRVGVVTFPGSLDDKQTLRALSFAGCAAVQLWHASDTLSSVDAVILPGGFSYGDYLRPG
CEEEEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCC
ALASRSRIMVRIIEAAHQGMPVLGICNGFQLLTESRLLPGAFVANKASRFVCLEQSLIVE
CCCHHHHHHHHEEHHHHCCCCEEEECCCHHHHHHCCCCCCHHHHCCCCEEEEEECEEEEE
NNSTPFTMNFSKNQNVIIPIKNSDGCYFAQTEDLDRIENEGRVVLRYAGSNPSGSSRNIA
CCCCCEEEEECCCCEEEEEEECCCCEEEECCCCHHHHCCCCEEEEEECCCCCCCCCCCEE
GICNEQGNIVGMMPHPEYAVEPGFGPPGLHGAPVFSAISSWINNAR
EEECCCCCEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA