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The map label for this gene is infC

Identifier: 28572755

GI number: 28572755

Start: 689959

End: 690507

Strand: Reverse

Name: infC

Synonym: TW608

Alternate gene names: 28572755

Gene position: 690507-689959 (Counterclockwise)

Preceding gene: 28572756

Following gene: 161501888

Centisome position: 74.57

GC content: 50.09

Gene sequence:

>549_bases
GTGGGCGAAAGTATTACCGCACCAGAAGTGCGGCTTATAAATAGCGATGGTGGTCCGTTGGGTGTTGTGTCCCGTTCGGT
TGCGCTTAGGCTGGCAGGTGAGGTTGGGTTGGACCTTGTTGAGGTTTCCCCATTTTCCAAGCCGCCAGTTGTAAAAATAA
TGGATTATGGGAAGTTTAGGTATGAGGCCTCCCAAAAAGCGAAGGAAGCTCGTCGCAGACAGAGTGGCGTTTCGGTCAAA
GAGGTGCGCTTCCGTCTCAAGATATGCGATAACGACTATGATGTCAAGCTTCGCAAGGCCATTTCTTTTCTCCAAGCCGG
CGATAAGGTAAAGGTTATGATACTTTTCCGGGGCCGTGAACAGTCTAGGCCGGAGCTTGGGGTGAAGCTTTTGAAGAAAT
TTGCTGATGATATTTCCGAGTTCGGGTCTGCCGATTCGCTTTCCAGAACCGACGGGCGCGGGATGGCTATCATGGTAAGC
CCTATAAAAAGCAAGACAATTGTTCGGGAAAAATCTTCGCATGCGCAAAAGGGTGACAAACAGCCGTGA

Upstream 100 bases:

>100_bases
GCCCGGATTCCTGCGTGTTTTGTCACCTTTCTGACGCCGCCGGTTTCCTTGTATTTATTCTGTTTGAGTTTGTTAGGGGG
ATGAAATAAACGAGCCTCGT

Downstream 100 bases:

>100_bases
ATGTAGCCGCATCCGTAAGTAGGTTTTGATTCACTTTGATGCTATAGTCTTCTTTGTATCTTAGGAGTGTTTGGTGCCAA
AACAGAAGACCCATTCGGGT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MGESITAPEVRLINSDGGPLGVVSRSVALRLAGEVGLDLVEVSPFSKPPVVKIMDYGKFRYEASQKAKEARRRQSGVSVK
EVRFRLKICDNDYDVKLRKAISFLQAGDKVKVMILFRGREQSRPELGVKLLKKFADDISEFGSADSLSRTDGRGMAIMVS
PIKSKTIVREKSSHAQKGDKQP

Sequences:

>Translated_182_residues
MGESITAPEVRLINSDGGPLGVVSRSVALRLAGEVGLDLVEVSPFSKPPVVKIMDYGKFRYEASQKAKEARRRQSGVSVK
EVRFRLKICDNDYDVKLRKAISFLQAGDKVKVMILFRGREQSRPELGVKLLKKFADDISEFGSADSLSRTDGRGMAIMVS
PIKSKTIVREKSSHAQKGDKQP
>Mature_181_residues
GESITAPEVRLINSDGGPLGVVSRSVALRLAGEVGLDLVEVSPFSKPPVVKIMDYGKFRYEASQKAKEARRRQSGVSVKE
VRFRLKICDNDYDVKLRKAISFLQAGDKVKVMILFRGREQSRPELGVKLLKKFADDISEFGSADSLSRTDGRGMAIMVSP
IKSKTIVREKSSHAQKGDKQP

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=163, Percent_Identity=44.1717791411043, Blast_Score=129, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_TROW8 (Q83HH0)

Other databases:

- EMBL:   BX251412
- RefSeq:   NP_789535.1
- ProteinModelPortal:   Q83HH0
- STRING:   Q83HH0
- GeneID:   1064814
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW608
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   KQMKFRL
- ProtClustDB:   PRK00028
- BioCyc:   TWHI218496:TW0580-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20111; Mature: 19979

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGESITAPEVRLINSDGGPLGVVSRSVALRLAGEVGLDLVEVSPFSKPPVVKIMDYGKFR
CCCCCCCCEEEEEECCCCCCHHHHHHHHHEEHHCCCCEEEEECCCCCCCEEEEECCCCHH
YEASQKAKEARRRQSGVSVKEVRFRLKICDNDYDVKLRKAISFLQAGDKVKVMILFRGRE
HHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCC
QSRPELGVKLLKKFADDISEFGSADSLSRTDGRGMAIMVSPIKSKTIVREKSSHAQKGDK
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHCCHHHHCCCCC
QP
CC
>Mature Secondary Structure 
GESITAPEVRLINSDGGPLGVVSRSVALRLAGEVGLDLVEVSPFSKPPVVKIMDYGKFR
CCCCCCCEEEEEECCCCCCHHHHHHHHHEEHHCCCCEEEEECCCCCCCEEEEECCCCHH
YEASQKAKEARRRQSGVSVKEVRFRLKICDNDYDVKLRKAISFLQAGDKVKVMILFRGRE
HHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCC
QSRPELGVKLLKKFADDISEFGSADSLSRTDGRGMAIMVSPIKSKTIVREKSSHAQKGDK
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHCCHHHHCCCCC
QP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12606174