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The map label for this gene is ftsW [C]

Identifier: 28572691

GI number: 28572691

Start: 578196

End: 579308

Strand: Reverse

Name: ftsW [C]

Synonym: TW543

Alternate gene names: 28572691

Gene position: 579308-578196 (Counterclockwise)

Preceding gene: 28572692

Following gene: 28572690

Centisome position: 62.56

GC content: 43.31

Gene sequence:

>1113_bases
ATGACAAAGCATAATAGGCTCATATCAGCAAATTATTTTTTATTATTGGCCAATGTGTTCGCACTGAATGCAATTGGGCT
GGTTATGGTTATATCGGCATCTACAGGCGTCAGTGATGATGGTGCTCGCTCGGTTATAAGCCAGATTATTTACACAGTTA
TCGGGTTTTTACTAATGTTTACCATTTCGGTTCTGCCCGAGCAGTTTTTTTTCCGATTTAGTAATATCTTTCTCATTGCT
GCGTGCATTTTGCAATCTGCTGTGCTGTCCCCACTTGGCGTAAACAGTGGGGGTAATACAAATTGGCTAAGATTTGGTCC
GATTACATTACAGCCGTCTGAGCTTTTGAAGCTTGCGGTGATTCTGTGGCTTGCAACAGGCCTGACGAAGAGACGCAGTA
CTTCGAGTGATTTGTCAAAGGGTGTTATACCGTCGTTTGTTGTGATTCTTGCGGTTTGTGGACTGGTATTTCTTGGCAAT
GACCTTGGGAATGTGTTGATTATTGTGATTATTTTCTTTGGGGTTATGATTTTTGCCAATATTCCTATGATCAGTCTTGC
ATTTCCCCTTGGCGTATTCTCTGGAATAGTATTTTTGGCCGCCACTTTGAGTCCGAATAGAATGGGGCGAATATTGAATT
TCTTGAATATAAGCTGTGACAAAGTGGACCAGCATTATTTGACGCTATGTTGGCAACCGATACAATCAGTGTGGGCTCTT
GCAAATGGAAATGTTGCGGGCGTTGGTTTAGGCAGGTCGGTGGCGAAGTGGAATTGGCTTCCGTCTGCTACAAGTGACTA
TATTTTTGCAATTCTTGGTGAAGAGTTAGGCTTTGTTGGTTCAATTTCCCTCATTCTGCTGTTTCTTTTTTTGGCTATTA
CTATGGTGAGGATTGCAAGAGATGCAAATGATCTTTTTGCGAGGTCTATTATCGGGGGTGTAATGTTTTGGCTTGTCGGG
CAGGCTCTTATAAATATCGCGGTTGTTCTAAGGTTTTTTCCGGTTTTGGGGGTTACCTTACCCTTTGTTTCTGCCGGAGG
CTCTGCCCTTACAACATCTATGATGGCTGTTGGGCTTGTTCTGGGGCTCATCCGCAGGTCTAGTCGCGCATAA

Upstream 100 bases:

>100_bases
TACTGTCACCGGGTGGTTCATCATTTGATCAGTTTGAGAGCTATGAGCATCGAGGCAATTGTTTTATAAATGCCGTGAAA
GATCTTGTCAAGCGTAAATA

Downstream 100 bases:

>100_bases
TGAGTAGGATTTTATTAGCAGGCGGCGGAACTGCGGGGCATGTAAATCCGCTGCTGGCGCTCGCAGATGTGCTGAAGGTA
TCTGGTCATGCTACATTTGC

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTKHNRLISANYFLLLANVFALNAIGLVMVISASTGVSDDGARSVISQIIYTVIGFLLMFTISVLPEQFFFRFSNIFLIA
ACILQSAVLSPLGVNSGGNTNWLRFGPITLQPSELLKLAVILWLATGLTKRRSTSSDLSKGVIPSFVVILAVCGLVFLGN
DLGNVLIIVIIFFGVMIFANIPMISLAFPLGVFSGIVFLAATLSPNRMGRILNFLNISCDKVDQHYLTLCWQPIQSVWAL
ANGNVAGVGLGRSVAKWNWLPSATSDYIFAILGEELGFVGSISLILLFLFLAITMVRIARDANDLFARSIIGGVMFWLVG
QALINIAVVLRFFPVLGVTLPFVSAGGSALTTSMMAVGLVLGLIRRSSRA

Sequences:

>Translated_370_residues
MTKHNRLISANYFLLLANVFALNAIGLVMVISASTGVSDDGARSVISQIIYTVIGFLLMFTISVLPEQFFFRFSNIFLIA
ACILQSAVLSPLGVNSGGNTNWLRFGPITLQPSELLKLAVILWLATGLTKRRSTSSDLSKGVIPSFVVILAVCGLVFLGN
DLGNVLIIVIIFFGVMIFANIPMISLAFPLGVFSGIVFLAATLSPNRMGRILNFLNISCDKVDQHYLTLCWQPIQSVWAL
ANGNVAGVGLGRSVAKWNWLPSATSDYIFAILGEELGFVGSISLILLFLFLAITMVRIARDANDLFARSIIGGVMFWLVG
QALINIAVVLRFFPVLGVTLPFVSAGGSALTTSMMAVGLVLGLIRRSSRA
>Mature_369_residues
TKHNRLISANYFLLLANVFALNAIGLVMVISASTGVSDDGARSVISQIIYTVIGFLLMFTISVLPEQFFFRFSNIFLIAA
CILQSAVLSPLGVNSGGNTNWLRFGPITLQPSELLKLAVILWLATGLTKRRSTSSDLSKGVIPSFVVILAVCGLVFLGND
LGNVLIIVIIFFGVMIFANIPMISLAFPLGVFSGIVFLAATLSPNRMGRILNFLNISCDKVDQHYLTLCWQPIQSVWALA
NGNVAGVGLGRSVAKWNWLPSATSDYIFAILGEELGFVGSISLILLFLFLAITMVRIARDANDLFARSIIGGVMFWLVGQ
ALINIAVVLRFFPVLGVTLPFVSAGGSALTTSMMAVGLVLGLIRRSSRA

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=354, Percent_Identity=30.7909604519774, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786853, Length=339, Percent_Identity=29.2035398230088, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 39844; Mature: 39713

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKHNRLISANYFLLLANVFALNAIGLVMVISASTGVSDDGARSVISQIIYTVIGFLLMF
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
TISVLPEQFFFRFSNIFLIAACILQSAVLSPLGVNSGGNTNWLRFGPITLQPSELLKLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCEEECHHHHHHHHH
ILWLATGLTKRRSTSSDLSKGVIPSFVVILAVCGLVFLGNDLGNVLIIVIIFFGVMIFAN
HHHHHHCCHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
IPMISLAFPLGVFSGIVFLAATLSPNRMGRILNFLNISCDKVDQHYLTLCWQPIQSVWAL
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ANGNVAGVGLGRSVAKWNWLPSATSDYIFAILGEELGFVGSISLILLFLFLAITMVRIAR
CCCCEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
DANDLFARSIIGGVMFWLVGQALINIAVVLRFFPVLGVTLPFVSAGGSALTTSMMAVGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LGLIRRSSRA
HHHHHHCCCC
>Mature Secondary Structure 
TKHNRLISANYFLLLANVFALNAIGLVMVISASTGVSDDGARSVISQIIYTVIGFLLMF
CCCCCEEHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
TISVLPEQFFFRFSNIFLIAACILQSAVLSPLGVNSGGNTNWLRFGPITLQPSELLKLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCEEECHHHHHHHHH
ILWLATGLTKRRSTSSDLSKGVIPSFVVILAVCGLVFLGNDLGNVLIIVIIFFGVMIFAN
HHHHHHCCHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
IPMISLAFPLGVFSGIVFLAATLSPNRMGRILNFLNISCDKVDQHYLTLCWQPIQSVWAL
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ANGNVAGVGLGRSVAKWNWLPSATSDYIFAILGEELGFVGSISLILLFLFLAITMVRIAR
CCCCEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
DANDLFARSIIGGVMFWLVGQALINIAVVLRFFPVLGVTLPFVSAGGSALTTSMMAVGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LGLIRRSSRA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]