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The map label for this gene is murG

Identifier: 28572690

GI number: 28572690

Start: 577126

End: 578196

Strand: Reverse

Name: murG

Synonym: TW542

Alternate gene names: 28572690

Gene position: 578196-577126 (Counterclockwise)

Preceding gene: 28572691

Following gene: 28572689

Centisome position: 62.44

GC content: 47.81

Gene sequence:

>1071_bases
ATGAGTAGGATTTTATTAGCAGGCGGCGGAACTGCGGGGCATGTAAATCCGCTGCTGGCGCTCGCAGATGTGCTGAAGGT
ATCTGGTCATGCTACATTTGCGCTTGGTACATCTGAGGGGATTGAAAGTCGCCTTGTACCAAATTCGGGTATCGATTTTT
TTACGATACCGAAGTTGCCCTTTCCCAGGAGGACCAGTAGACATATCTTGTGTTTTCCCTTTAAGTTTTTTTCTTCCGTC
AAGCTTGTTAGATCGATTCTTATTGAGCACAAGATTCAAGTGGTTGTCGGGTTTGGGGGATATGTGGCAGCTCCTGCCTA
TGCCGCTGCGATCAGCCTAAATATTCCATACGTAGTGCATGAGTCGAATGCCAGGCCTGGGTTGGCAAATCTTCTTGCTG
CGCATTTTGCAAAGTGTGTGGGTATTTCTGTGATAGGTGCCTTACCGTGCGGAAAACTTGTTGGAACTCCGATTAGGCGC
GATCTTACTGCGGCGGCTTCTTTTGATCCTGTTTTGGCAAAGGAGAAGCTTGGGTTGGACCCGGTGAGAAAACTTCTTCT
TGTTTTTGGTGGCTCACAGGGCAGCGCGAAGATTAACATGCATATGCGTGCGGCGTTGCCCAGAGTGCTCAAGTTATGCG
ATGAGAAGAATTATTTATGGCAAGTCTTGCATATAACCGGATACGGCGATTCTATTGATGTGAACATGCCTCATTATAGC
TCTGTGCGTTATATGGACAGTATGGGTTACGCCCTTTCTGCAGCTGACCTCGTTGTTAGTCGTGCGGGGTCCAGTACAGT
TGCAGAGTTGTGCACCTTTGGTATCCCGGCAATATATATCCCTTATCCATTTGGTAATGGTGAACAGAGGCGCAATGTCT
CTCATATGGAGAGCGCAGCGCGTATTATTCAGGAGAATGATCTTTCTCAGATACGTCTTGAAGACGAGCTCCTAGAGCTT
ATGACTGACGATGAACGGCGTGAGGCAATGTCCATTGCGGCAAAACGGTTTGCTATCTGTAATGCTGCCCAAAATACTGC
GAGCCTGATTGAGCTCGCACTTTCCTCTTAG

Upstream 100 bases:

>100_bases
TTACCTTACCCTTTGTTTCTGCCGGAGGCTCTGCCCTTACAACATCTATGATGGCTGTTGGGCTTGTTCTGGGGCTCATC
CGCAGGTCTAGTCGCGCATA

Downstream 100 bases:

>100_bases
GCATGGGGATTTATGCGAAGGACGTACCCCTTCCCGAATCAATAAATAGAGCTCACTTTTGTGGTATTGGCGGTTCTGGT
ATGTCCGCAGTTGCAAGGCT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSRILLAGGGTAGHVNPLLALADVLKVSGHATFALGTSEGIESRLVPNSGIDFFTIPKLPFPRRTSRHILCFPFKFFSSV
KLVRSILIEHKIQVVVGFGGYVAAPAYAAAISLNIPYVVHESNARPGLANLLAAHFAKCVGISVIGALPCGKLVGTPIRR
DLTAAASFDPVLAKEKLGLDPVRKLLLVFGGSQGSAKINMHMRAALPRVLKLCDEKNYLWQVLHITGYGDSIDVNMPHYS
SVRYMDSMGYALSAADLVVSRAGSSTVAELCTFGIPAIYIPYPFGNGEQRRNVSHMESAARIIQENDLSQIRLEDELLEL
MTDDERREAMSIAAKRFAICNAAQNTASLIELALSS

Sequences:

>Translated_356_residues
MSRILLAGGGTAGHVNPLLALADVLKVSGHATFALGTSEGIESRLVPNSGIDFFTIPKLPFPRRTSRHILCFPFKFFSSV
KLVRSILIEHKIQVVVGFGGYVAAPAYAAAISLNIPYVVHESNARPGLANLLAAHFAKCVGISVIGALPCGKLVGTPIRR
DLTAAASFDPVLAKEKLGLDPVRKLLLVFGGSQGSAKINMHMRAALPRVLKLCDEKNYLWQVLHITGYGDSIDVNMPHYS
SVRYMDSMGYALSAADLVVSRAGSSTVAELCTFGIPAIYIPYPFGNGEQRRNVSHMESAARIIQENDLSQIRLEDELLEL
MTDDERREAMSIAAKRFAICNAAQNTASLIELALSS
>Mature_355_residues
SRILLAGGGTAGHVNPLLALADVLKVSGHATFALGTSEGIESRLVPNSGIDFFTIPKLPFPRRTSRHILCFPFKFFSSVK
LVRSILIEHKIQVVVGFGGYVAAPAYAAAISLNIPYVVHESNARPGLANLLAAHFAKCVGISVIGALPCGKLVGTPIRRD
LTAAASFDPVLAKEKLGLDPVRKLLLVFGGSQGSAKINMHMRAALPRVLKLCDEKNYLWQVLHITGYGDSIDVNMPHYSS
VRYMDSMGYALSAADLVVSRAGSSTVAELCTFGIPAIYIPYPFGNGEQRRNVSHMESAARIIQENDLSQIRLEDELLELM
TDDERREAMSIAAKRFAICNAAQNTASLIELALSS

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=355, Percent_Identity=34.3661971830986, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_TROW8 (Q83HK1)

Other databases:

- EMBL:   BX251411
- RefSeq:   NP_789470.1
- ProteinModelPortal:   Q83HK1
- STRING:   Q83HK1
- GeneID:   1064745
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW542
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   PHGNGEQ
- PhylomeDB:   Q83HK1
- ProtClustDB:   PRK00726
- BioCyc:   TWHI218496:TW0515-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38421; Mature: 38290

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRILLAGGGTAGHVNPLLALADVLKVSGHATFALGTSEGIESRLVPNSGIDFFTIPKLP
CCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHCCCCCCCCCEEEECCCC
FPRRTSRHILCFPFKFFSSVKLVRSILIEHKIQVVVGFGGYVAAPAYAAAISLNIPYVVH
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHCEEEEEEECCCHHHCCHHHEEEEECCCEEEE
ESNARPGLANLLAAHFAKCVGISVIGALPCGKLVGTPIRRDLTAAASFDPVLAKEKLGLD
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHCCCCCHHHHHHCCHH
PVRKLLLVFGGSQGSAKINMHMRAALPRVLKLCDEKNYLWQVLHITGYGDSIDVNMPHYS
HHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEECCCCCCC
SVRYMDSMGYALSAADLVVSRAGSSTVAELCTFGIPAIYIPYPFGNGEQRRNVSHMESAA
CHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCHHHCCHHHHHHHH
RIIQENDLSQIRLEDELLELMTDDERREAMSIAAKRFAICNAAQNTASLIELALSS
HHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SRILLAGGGTAGHVNPLLALADVLKVSGHATFALGTSEGIESRLVPNSGIDFFTIPKLP
CEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHCCCCCCCCCEEEECCCC
FPRRTSRHILCFPFKFFSSVKLVRSILIEHKIQVVVGFGGYVAAPAYAAAISLNIPYVVH
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHCEEEEEEECCCHHHCCHHHEEEEECCCEEEE
ESNARPGLANLLAAHFAKCVGISVIGALPCGKLVGTPIRRDLTAAASFDPVLAKEKLGLD
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHCCCCCHHHHHHCCHH
PVRKLLLVFGGSQGSAKINMHMRAALPRVLKLCDEKNYLWQVLHITGYGDSIDVNMPHYS
HHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEECCCCCCC
SVRYMDSMGYALSAADLVVSRAGSSTVAELCTFGIPAIYIPYPFGNGEQRRNVSHMESAA
CHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCHHHCCHHHHHHHH
RIIQENDLSQIRLEDELLELMTDDERREAMSIAAKRFAICNAAQNTASLIELALSS
HHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12606174