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The map label for this gene is ruvC [H]

Identifier: 28572652

GI number: 28572652

Start: 542124

End: 542675

Strand: Reverse

Name: ruvC [H]

Synonym: TW503

Alternate gene names: 28572652

Gene position: 542675-542124 (Counterclockwise)

Preceding gene: 28572653

Following gene: 28572651

Centisome position: 58.61

GC content: 46.74

Gene sequence:

>552_bases
ATGCGAATAATGGCTGTTGATCCTGGCTTGACCAATTGTGGAGTGGCCGTTGTAAATGCGACCGGGCCTCTTTCTCTTGA
GCTCTTGGCGGTAAAAGTTTTTCATACCGATAGATCTTTGTCATTTGAAAATCGTATTGGAAAGATTGGTGATAGTCTTC
TATCAATGCTCGAGGAGTTTTCCCCGGATTTATTTGCGCTTGAAAAGGTGTTCGCGCAGCATAATTTGAGTACAGTGAGT
GGCGTTGCGGGTGTTATAGGCGTGGCGAGTTATCTATGTTACAAACATGGTACCCATATTGCGTTTCACACACCGAGCGA
AATAAAGGCCTCTATTTGTGGGTATGGAAACGCAAAGAAGGATCAAATTCGTAGCATGGTAAATAGGGTTTTTTTATCCC
AAGATATTCCACTCAGGCATGATGCGTCAGATGCTTTGGCCCTTGCTGTATGTTGCGCCAGGCGATATGCACTGCACAAT
GAGCATTTTACCGAGGCGAGGCTGCGATGGCTATCAGCACTCGGGGCCAGTTCGACAGAGCGGGGTCGGTAA

Upstream 100 bases:

>100_bases
CAGAGCAAAAATACGATCGGATTATTCGCATGATAGAAGCTCTCGAGGAGAGTGATGATGTTCAGGGTGTCTATACAAAT
CTTTCCGGGAAAGACCTCGC

Downstream 100 bases:

>100_bases
GTGTCTGTATATGCATTGCTTGCACCGGAGGGCTTGCTTTGATCGCGTCACTTTCTGGATTGTTGGAGGCTGTACGTCCC
GGAAGTGTTGTTGTGAACAT

Product: crossover junction endodeoxyribonuclease RuvC

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MRIMAVDPGLTNCGVAVVNATGPLSLELLAVKVFHTDRSLSFENRIGKIGDSLLSMLEEFSPDLFALEKVFAQHNLSTVS
GVAGVIGVASYLCYKHGTHIAFHTPSEIKASICGYGNAKKDQIRSMVNRVFLSQDIPLRHDASDALALAVCCARRYALHN
EHFTEARLRWLSALGASSTERGR

Sequences:

>Translated_183_residues
MRIMAVDPGLTNCGVAVVNATGPLSLELLAVKVFHTDRSLSFENRIGKIGDSLLSMLEEFSPDLFALEKVFAQHNLSTVS
GVAGVIGVASYLCYKHGTHIAFHTPSEIKASICGYGNAKKDQIRSMVNRVFLSQDIPLRHDASDALALAVCCARRYALHN
EHFTEARLRWLSALGASSTERGR
>Mature_183_residues
MRIMAVDPGLTNCGVAVVNATGPLSLELLAVKVFHTDRSLSFENRIGKIGDSLLSMLEEFSPDLFALEKVFAQHNLSTVS
GVAGVIGVASYLCYKHGTHIAFHTPSEIKASICGYGNAKKDQIRSMVNRVFLSQDIPLRHDASDALALAVCCARRYALHN
EHFTEARLRWLSALGASSTERGR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 19930; Mature: 19930

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIMAVDPGLTNCGVAVVNATGPLSLELLAVKVFHTDRSLSFENRIGKIGDSLLSMLEEF
CEEEEECCCCCCCCEEEEECCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
SPDLFALEKVFAQHNLSTVSGVAGVIGVASYLCYKHGTHIAFHTPSEIKASICGYGNAKK
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCH
DQIRSMVNRVFLSQDIPLRHDASDALALAVCCARRYALHNEHFTEARLRWLSALGASSTE
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
RGR
CCC
>Mature Secondary Structure
MRIMAVDPGLTNCGVAVVNATGPLSLELLAVKVFHTDRSLSFENRIGKIGDSLLSMLEEF
CEEEEECCCCCCCCEEEEECCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
SPDLFALEKVFAQHNLSTVSGVAGVIGVASYLCYKHGTHIAFHTPSEIKASICGYGNAKK
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCH
DQIRSMVNRVFLSQDIPLRHDASDALALAVCCARRYALHNEHFTEARLRWLSALGASSTE
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
RGR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA